Evaluation of the antioxidant effects of resveratrol against hyperglycemia - Induced oxidative stress in Type 2 diabetic rat model

Journal of Applied Sciences Research

Volumn 8, Issue 3, 2012, Pages 1576-1584

  Atef, Azza A ^a   Ezz, Magda K ^a  

^a Ain Shams University   (Egypt)

Author keywords

Antioxidant enzymes; Oxidative stress; Resveratrol; Type 2 diabetes

Indexed keywords

EID: 84865976359     PISSN: 1816157X     EISSN: 1819544X     Source Type: Journal    
DOI: None     Document Type: Article

References (72)

1. Aebi, H., 1984. Catalase. In: Bergmeyer, H.U. (Ed). Methods of Enzymatic Analysis. Chemic. Academic Press Inc. Verlag, pp: 653-85.
2. Aggarwal, B.B., A. Bhardwaj, R.S. Aggarwal, et al., 2004. Role of resveratrol in prevention and therapy of cancer: pre-clinical and clinical studies. Anticancer Res., 24: 2783.
3. American Diabetes Association, 2008. Diagnosis and classification of diabetes mellitus. Diabetic care, 31: 555-560.
4. Atef, A.A., M.K. Ezz and N.K. Ibrahim, 2011. Resveratrol,a natural phtoalexin:a therabutic promise for metabolic disorders in streptozotocin - nicotinamide induced type 2 diabetic rats. EJB., 29(1): 175-194.
5. Ates, O., S. Cayli, E. Altinoz, et al., 2007. Neuroprotection by resveratrol against traumatic brain injury in rats. Mol. Cell. Biochem., 2294: 137-144.
6. Baker, H., O. Frankel, et al., 1980. Plasma α-tocopherol in man at various time intervals after ingesting free or acetylated to copherol. Nutr, Rep. Int., 21: 531-536.
7. Beauchamp and I. Fridovish, 1971. Superoxide dismutase: improved assays and assay applicable to acrylamide gels. Anal Biochem., 44(1): 276-287.
8. Bertelli, A.A., L. Giovannini, R. Stradi, et al., 1996. Kinetics of trans- and cis-resveratrol (3,4',5-trihydroxystilbene) after red wine oral administration in rats. Int. J. Clin. Pharmacol. Res., 16: 77-81.
9. Beutler, E., O. Duron and B.M. Kelly, 1963. Improved method for the determination of blood glutathione, J. Lab. Clin. Med., 61(5): 882-888.
10. Bhardwaj, A., G. Sethi, S. Vadhan-Raj, et al., 2007. Resveratrol inhibits proliferation, induces apoptosis and overcomes chemoresistance through down regulation of STAT 3 and nuclear factor-Kappa B- regulated anti-apoptotic and cell survival gene products in human myeloma cells. Blood, 109: 2293-2302.
11. Bhat, K.P., D. Lantvit, K. Christov, et al., 2001. Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. Cancer Res., 61: 7465-7463.
12. Bode, A.M., C.R. Yavarow, D.A. Fry and T. Vargas, 1993. Enzymatic basis for altered ascorbic acid and dehydroascorbic acid levels in diabetes. Biochem. Biophys. Res. Commun., 191: 1347-1353.
13. Brown, A.A. and F.B. Hu, 2001. Dietary modulation of endothelial function: implications for cardiovascular disease. Am. J. Clin. Nutr., 73: 673-686.
14. Ceriellio, A., N. Bortalotti, A. Grescentini, et al., 1998. Antioxidant defences are reduced during the oral glucose tolerance test in normal and non insulin-dependent diabetic subjects. Eur. J. Clin, Invest., 28: 329-33.
15. Chandra, A., A.A. Mahdi, S. Ahmed and R.K. Singh, 2007. Indian herbs result in hypoglycemic responses in streptozotocin-induced diabetic rats. Nutr. Res., 27(3): 161-168.
16. Chen, S. and P. Schopfer, 1999. Hydroxyl radical production in physiological reactions. A novel function of peroxidase. Eur. J. Biochem., 260: 726-735.
17. Chow, C.K., 1991. Vitamin E and oxidative stress. Free Radic. Biol. Med., 11: 215-232.
18. Das, D.K. and N. Maulik, 2006. Resveratrol in cardioprotection: A therapeutic promise of alternative medicine. Mol. Interven., 6(1): 36-45.
19. Das, S., C.G. Fraga and D.K. Das, 2006. Cardioprotective effect of resveratrol via HO-1 expression involves p 38 map kinase and P1-kinase signaling, but does not involve NF Kappa B. Free rad, 40: 1066-1075.
20. Davi, G., A. Falco, C. Patrono, 2005. Lipid peroxidation in diabetes mellitus. Antioxid. Redox. Signal, 7: 256-268.
21. Djahansouzi, S., J.H. Braesen, K. Koenig, et al., 2001. The effect of pharmacological doses of different antioxidants on oxidation parameters and atherogenesis in hyperlipidaemic rabbits. Atherosclerosis, 154: 387-398.
22. Goldberg, D.M., J. Yan, G.J. Soleas, 2003. Absorption of three wine- related polyphenols in three different matrices by healthy subjects Clin. Biochem., 36: 79-87.
23. Halliwell, B. and J.M.C. Gutteridge, 1994. Lipid peroxidation, oxygen radicals, cell damage and antioxidant theraby. Lancet, 344: 1396-7.
24. Hattori, R., H. Otani, N. Maulik and D.K. Das, 2002. Pharmacological preconditioning with resveratrol: role of nitic oxid .Am.J.Physiol.Heart physiol., 282(6): H1988-95.
25. Honing, M.L., P.J. Morrison, D.J. Banga, et al., 1998. Nitric oxide availability in diabetes mellitus. Diabetes. Metab. Rev., 14: 241-249.
26. Jennings, P.E., N.A. Scott, A.R. Saniabadi and J.J. Blech, 1992. Effect of Gliclazide on platelet reactivity and free radicals in type 11 diabetic patients. Clinical Assessment Metabolism, 41: 36-39.
27. Jessup, W., R.T. Dean, C.V. de Whalley, et al., 1990. The role of oxidative modification and antioxidants in LDL metabolism and atherosclerosis. Adv. Exp. Med. Biol., 264: 139-142.
28. Jia, Z., J. Zhu, B.R. Misra, et al., 2008. EPR studies on the super oxide-scavenging capacity of the nutraceutical resveratrol. Mol. Cell. Biochem., 313: 187-194.
29. Kaleem, M., M. Asif, O.U. Ahmed and B. Bano, 2006. Antidiabetic and antioxidant activity of Annona Squamosa extract in strepto-zotocin-induced diabetic rats. Singapore Med J., 47(8): 670-675.
30. Kaneto, H., D. Kawamori, T.A. Matsuoka, et al., 2005. Oxidative stress and pancreatic beta-cell dysfunction. Am. J. Ther., 12: 529-533.
31. Kimoto, K., K. Suzuki, T. Kizaki, et al., 2003. Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide. Biochem. Biophy. Res. Commun., 303: 112-119.
32. Lamattina, L., C. Garcia-Mata, M. Graziano and G. Pagnussat, 2003. Nitric oxide, The varsality of an extensive signal molecule. Ann. Rev. Plant. Biol., 54: 109-136.
33. Leonard, S.S., C. Xia, B.H. Jiang, et al., 2003. Resveratrol scavenges reactive oxygen species and effects radical-induced cellular response. Biochem. Res. Common., 309: 1017.
34. Leung, P.S. and Y.C. Chan, 2009. Role of oxidative stress in pancreatic inflammation. Antioxid. Redox. Signal., 11: 135-165.
35. Liedias, F., B. Rangel and W. Hansberg, 1998. Oxidation of catalase by siglet oxygen. J. Biol. Chem., 273: 10630-10637.
36. Lowry, O.H., N.J. Rosebrough, A.I. Farr and R.J. Randall, 1951. Protein measurement with the folin phenol reagent J. Biol. Chem., 193: 269-275.
37. Martin, A.C., R.A. Sanders and J.B.III Watkins, 2003. Diabetes, oxidative stress and antioxidants: A review. J. Biochem. Mol. Toxicol., 17: 24-38.
38. Markus, M.A. and B.J. Morris, 2008. Resveratrol in prevention and treatment of common clinical conditions of aging. Clin. Interv. Aging., 3: 331-339.
39. Masiello, P., C. Broca, R. Gross, et al., 1998. Experimental NIDDM: Development of a new model in adult rats administered streptozotocin and nicotinamide. Diabetes, 47: 224-229.
40. McCord, J.M., B.B. Keele and I. Fridorich, 1976. An enzyme based theory of obligate anaerobiosis? The Physiological functions of superoxide dismutase. Proc. Nath. Acad. Sci. USA., 68: 1024.
41. Melov, S., 2002. Animal models of oxidative stress, aging and therapeutic antioxidant interventions. Int. J. Biochem. Cell. Biol., 34: 1395-1400.
42. Mendez, J.D. and F. Balderas, 2001. Regulation of hyperglycemia and dyslipidemia by exogenous L-arginine in diabetic rats. Biochem., 83: 453-458.
43. Miranda, M., M.G. Espey and D.A. Wink, 2001. A rapid simple spectrophotometric method for simultaneous detection of nitrate and nitrite, Nitric Oxide, 5: 62-71.
44. Nayak, S.S. and T.N. Pattabiraman, 1981. A new colorimetric method for the estimation of glycosylated hemoglobin. Clin. Chem. Acta., 109: 267-274.
45. Palsamy, P. and S. Subramanian, 2008. Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced diabetic rats.Biomedicine-Phamacotherapy, 62: 598-605.
46. Pandey, K.B. and S.I. Rizvi, 2010a. Antioxidative action of resveratrol: implications for human health. Arab. J. Chem., 6: 1-6.
47. Pandey, K.B. and S.I. Rizvi, 2010b. Resveratrol may protect plasma proteins from oxidation under conditions of oxidative stress in vitro. J. Braz. Chem. Soc., 21: 909-913.
48. Pari, L. and S. Suman, 2010. Antihyperglycemic and antilipidperoxi-dative effects of flavanoid natringin in streptozotocin-nicotinamide induced diabetic rats. Int. J. Biol. Med. Res., 1(4): 206-210.
49. Penumasthsa, S.V., M. Thirunavukkarasu, L. Zhan, et al., 2008. Resveratrol enhances GLUT-4 translocation to the cawealar lipid raft fractions through AMPK/AKT/ENOS signaling pathway in diabetic myocardium. J. Cell. Mol. Med., 12(6A): 2350-2361.
50. Punitha, I.S.R., K. Rajendra, A. Shirwaikar and A. Shiwaikar, 2005. Alcoholic stem extract of cascinium fenestratum regulates carbohydrate metabolism and improves antioxidant status in streptozotocin nicotine amide induced diabetic rats. Evid Based Complement Alternate Med., 2(3): 375-381.
51. Rizvi, S.I. and P.K. Maurya, 2007. Markers of oxidative stress in erythrocytes during aging in humans. Ann. N.Y. Acad. Sci., 1100: 373-382.
52. Rizvi, S.I. and M.A. Zaid, 2001. Intracellular reduced glutathione content in normal and Type 2 diabetic erythrocytes: Effect of insulin and (-) Epicatechin. J. Physiol. Pharmacol., 52: 483-488.
53. Roe, J.H. and C.A. Kuether, 1943 Detection of ascorbic acid in whole blood and urine through 2,4 DNPH derivatives of dehydroascorbic acid. J. Biol. Chem., 147: 399-407.
54. Sadruddin, S. and R. Arora, 2009. Resveratrol biology and therapeutic implications. J. Cardiometab. Syndr., 4: 102-106.
55. Satheesh, M.A. and L. Pari, 2004. Antioxidant effect of Boerhavia diffusa L. in tissues of alloxan induced diabetic rats. Indian J. Exp. Biol., 42(10): 989-992.
56. Scott, N.A., P.E. Jennings, J. Brown and J.J. Belch, 1992. Gliclazide: A general free radical scavenger. Eur. J. Pharmacol., 208: 175-177.
57. Seven, A., S. Güzel, O. Seymen, et al., 2004. Effects of vitamin E supplementation on oxidative stress in streptozotocin induced diabetic rats; investigation of liver and plasma. Yonsei Medical. Journal, 45(4): 703-710.
58. Shima, K., M. Zhu and M. Kuwajima, 1998. A role of nicotinamide induced increase in pancreatic B-cell mason blood glucose control after discontinuation of the treatment in partially pancreatectomized OLETF rats. Diabetes Res. Clin. Pract., 41: 1-8.
59. Spinas, A.G., 1999. The dual role of nitric oxide in islet B-cells. New Physiol. Sci., 14: 49.
60. Su, H., L. Hung and J. Chen, 2006. Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats. Am. J. Physiol. Endocrinol. Metab., 290: E1339-E1346.
61. Sun, F., K. Iwaguchi, R. Shudo, et al., 1999. Change in tissue concentration of lipid peroxides, vitamin C and vitamin E in rats with streptozotocine induced diabetes. Clin. Sci. (London), 96: 185-190.
62. Thompson, K.H., D.V. Godin and M. Lee, 1992. Tissue antioxidant status in streptozotocin-induced diabetes in rats. Effect of dietary manganese deficiency. Biol. Trace. Element Res., 35: 213-224.
63. Trinder, P., 1969. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Am. J. Clin. Biochem., 6: 24-33.
64. Uchiyama, M. and M. Mihara, 1978. Determination of malondialdhyde precursor in tissues by thiobarbituric acid test. Analy. Biochem., 86: 271-278.
65. Ursini, F., M. Maiorino, R. Brigeluis-Flahe, et al., 1995. Diversity of glutathione peroxidase. Methods in enzymology, 252: 38-53.
66. Wang, L., O. Ma, X. Chen, M. Sha and Z. Ma, 2008. Effect of resveratrol on calcium regulation in rats with severe acute pancreatitis. Eur. J. Pharmacol., 580: 271-276.
67. Wiernsperger, N.F., 2003. Oxidative stress as a therapeutic target in diabetes: revisiting the contravery, Diabetes Meta, 29(6): 579-585.
68. Xiong, Y., Y.S. Fu and H. Zhou, 2003. Elevated levels of serum endogenous inhibitor of nitric oxide synthase and metabolic control in rats with streptozotocin-induced diabetes. J. Cardiovasc. Pharmacol., 42: 191-196.
69. Yen, G.G., P.D. Duh, C.W. Lin, 2003. Effect of resveratrol and 4-hexylresoainol on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes. Free Radic. Res., 37: 509-514.
70. Young, I.S., S. Tate, J.H. Lightbody, et al., 1995. The effects of desferrioxamine and ascorbate on oxidative stress in the streptozotocin diabetic rats. Free. Rad. Biol. Med., 18: 833-840.
71. Young, I.S., J.J. Torney and E.R. Trimble, 1992. The effect of ascorbate supplementation on oxidative stress in the streptozotocin diabetic rats. Free Rad. Biol. Med., 13: 41-46.
72. Yu, B.P., 1994. Cellular defenses against damage from reactive oxygen species. Physiol Rev., 74: 136-162.