Indian herbs result in hypoglycemic responses in streptozotocin-induced diabetic rats

Nutrition Research

Volumn 27, Issue 3, 2007, Pages 161-168

  Chandra, Anu ^a   Mahdi, Abbas Ali ^a   Ahmad, Sohail ^b   Singh, Raj Kumar ^a  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b Government Unani Medical College   (India)

Author keywords

Antioxidant potential; Diabetes; Herbal hypoglycemic agents; Streptozotocin induced diabetic rats

Indexed keywords

AZADIRACHTA INDICA EXTRACT; CATALASE; GARLIC EXTRACT; GLIBENCLAMIDE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INSULIN; LIPID PEROXIDE; MOMORDICA CHARANTIA EXTRACT; OCIMUM SANCTUM EXTRACT; STREPTOZOCIN; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; AZADIRACHTA INDICA; BASIL; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; ENZYME REACTIVATION; GARLIC; HYPOGLYCEMIA; INDIA; LIPID PEROXIDATION; MALE; MOMORDICA CHARANTIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ALLIUM SATIVUM; AZADIRACHTA INDICA; MOMORDICA CHARANTIA; OCIMUM TENUIFLORUM; RATTUS; SATIVUM;

EID: 33947127110     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nutres.2006.12.008     Document Type: Article

References (53)

1. McCarty P., and Zimmet P. Diabetes 1994-2010: global estimate and projections. Diabetes Care 20 (1997) 1785-1790
2. Leahy J.L. Pathogenesis of type 2 diabetes mellitus. Arch Med Res 36 (2005) 197-209
3. La Selva M., Beltramo E., Passera P., Porta M., and Molinatti G.M. The role of endothelium in the pathogenesis of diabetic microangiopathy. Acta Diabetol 30 (1993) 190-200
4. Devi G., Falco A., and Patrono C. Lipid peroxidation in diabetic mellitus. Antioxid Redox Signal 7 (2005) 256-268
5. Lapolla A., and Fedele D. Oxidative stress and diabetes: role in the development of chronic complications. Minerva Endocrinol 18 3 (1993) 99-108
6. Leonid E.F., and Philipson L.H. Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic β-cells?. Diabetes 53 (2004) 1942-1948
7. Fabryova L., and Cagan S. Free oxygen radicals in atherosclerosis and diabetes mellitus. Bratisl Lek Listy 96 1 (1995) 23-29
8. Scott J.A., and King G.L. Oxidative stress and antioxidant treatment in diabetes. Ann N Y Acad Sci 1031 (2004) 204-213
9. Jabeen R., and Saleemudin M. Polyclonal antibodies inhibit the glycation-induced inactivation of bovine Cu, Zn-superoxide dismutase. Biotechnol Appl Biochem 43 (2006) 49-53
10. Segal K.R. Type 2 diabetes and disease management: exploring the connections. Dis Manag 7 Suppl (2004) s11-s22
11. Marles R.J., and Farnsworth N.R. Antidiabetic plants and their active constituents. Phytomedicine 2 (1995) 133-189
12. Alarcon-Aguilara F.J., Roman-Ramos R., Perez-Gutierrez S., Aguilar-Contreras A., Contreras-Weber C.C., and Flores-Saenz J.L. Study of the antihyperglycemic effect of plants used as antidiabetic. J Ethnopharmacol 61 2 (1998) 101-110
13. Platel K., and Srinivasan K. Plant foods in the management of diabetes mellitus: vegetables as potential hypoglycemic agents. Die Nahrung 41 2 (1997) 68-74
14. Khan A., and Safdar M. Role of nutrients, spices and natural products in diabetes mellitus. Pakistan J Nutr 2 (2003) 1-12
15. Zacharis N.T., Sepastian K.L., Babu P., and Augusti K.T. Hypoglycemic and hypolipidemic effects of garlic in sucrose fed rabbits. Indian J Physiol Pharmacol 24 (1980) 151-153
16. Satyanarayan K., Murty D., Narayana Rai D., Krishna Rao D., and Gopalakrishna Murty L.B. A preliminary study on hypoglycemic and antihyperglycemic effects of Azadirachta indica. Indian J Pharm 10 3 (1978) 247-250
17. Karunanayake E.H., Jeevathayaparan S., and Tennekoon K.H. Effect of Momordica charantia fruit juice on streptozotocin-induced diabetes in rats. J Ethnopharmacol 30 (1990) 199-204
18. Luthy N., and Ortelio M. A study of a possible oral hypoglycemic factor in Albahaca morada (O. sanctum). Ohio J Sci 64 3 (1964) 222-224
19. Sheela C.G., and Augusti A.T. Antidiabetic effects of onion and garlic sulfoxide amino acids in rats. Planta Med 61 4 (1996) 356-357
20. Shibib B.A., Khan L.A., and Rahman R. Hypoglycemic activity of Coccinia indica and Momordica charantia in diabetic rats: depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1,6-bisphosphatase and elevation of both liver and red cell shunt enzyme glucose-6-phosphate dehydrogenase. Biochem J 292 (1993) 267-270
21. Thai medicinal plants, recommended for primary health care system. Ed. by R. Norman, Farnsworth NF, Bunyapraphatsara N. Published by Prachachon Co Ltd Compute and Graphic Art, Bangkok, Thailand. 1992, pp-10-34 and 183-187.
22. In: Schmutterer H. (Ed). The neem tree, source of unique natural products for integrated pest management, medicine, industry and other purposes (1995), VCH Publishers Inc., New York (USA) 35-89
23. Chevallier A. The encyclopedia of medicinal plants. A practical reference guide to over 550 key herbs and their medicinal uses. In: Chevallier A. (Ed) (1996), Dorling Kindersley Ltd., London (UK) 234
24. Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissue by thio-barbituric acid reaction. Anal Biochem 95 (1979) 258-357
25. Aebi H., and Suter H. Positive function of reduced glutathione (GSH) against the effect of peroxidative substances and of irradiation in the red cell. In: Flohe L., and Benhar H.C. (Eds). Glutathione (1974), Georg Thieme, Stuttgart 192-199
26. Tinder P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann Clin Biochem 6 (1969) 24-30
27. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 193 (1951) 265-275
28. McCord J.M., and Fridovich I. SOD enzyme function for erythrocuprein. J Biol Chem 224 (1969) 6049-6055
29. Beutler E., and Kelley B.M. The effect of sodium nitrate on red cell glutathione. Experientia 19 (1967) 96-97
30. Paglia D.E., and Valentine W.N. Studies on the qualitative and quantitative characterization of erythrocyte GPx. J Lab Clin Med 20 (1967) 150-168
31. Hazelton G.A., and Lang C.A. GSH content of tissue in aging mouse. Biochem J 188 (1980) 25-30
32. In: Woodson R.F. (Ed). Statistical methods for the analysis of biochemical data (1987), Wiley, Chichester 315
33. Khosla P., Bhanwra S., Singh J., Seth S., and Srivastava R.K. A study of hypoglycemic effects of Azadirachta indica (neem) in normal and alloxan diabetic rabbits. Indian J Physiol Pharmacol 44 1 (2000) 69-74
34. Davis S.N., and Granner D.K. Insulin, oral hypoglycemic agents and the pharmacology of endocrine pancreas. In: Hardman J.G., Limberd L.E., Malinoff P.B., Ruddon R.W., and Gilman A.G. (Eds). Goodman and Gilman's the pharmacological basis of therapeutics. 9th ed. (1996), McGraw Hill, New York 1487-1518
35. Seshiah V. Oral antidiabetic drugs. In: Seshiah V., Ganesen V.S., and Hasinarayanan C.V. (Eds). A handbook of diabetic mellitus (1998), Diabetic Education and Research Foundation, Chennai (India) 43-45
36. Sharma M.K., Khare A.K., and Feroz H. Effect of neem oil on blood sugar levels of normal, hyperglycemic and diabetic animals. Indian Med Gaz (1983) 380-383
37. Srinivasan K. Plant foods in the management of diabetes mellitus: spices as beneficial ant diabetic food adjuncts. Int J Food Sci Nutr 56 6 (2005) 399-416
38. Hannan J.M.A., Marenah L., Ali L., Rokeya B., Flatt P.R., and Abdel-Wahab Y.H.A. Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic β-cells. J Endocrinol 189 (2006) 127-136
39. Gallou G., Ruelland A., Legras B., Maugendre D., Allanic H., and Cloarec L. Plasma malondialdehyde in type 1 and type 2 diabetic patients. Clin Chim Acta 214 (1993) 227-234
40. Mahdi A.A., Chandra A., Singh R.K., Shukla S., Mishra L.C., and Ahmad S. Effect of herbal hypoglycemic agents on oxidative stress and anti-oxidant status in diabetic rats. Indian J Clin Biochem 18 2 (2003) 8-15
41. Zigler J.S., and Hess H.H. Evidence of initiation by lipid peroxidation products. Exp Eye Res 41 (1985) 67-76
42. Irshad M., and Chaudhuri P.S. Oxidant-antioxidant system: role and significance in human body. Indian J Exp Biol 40 (2002) 1233-1239
43. Vendemiale G., Grattagliano I., and Altomare E. An update on the role of free radicals and antioxidant defense in human disease. Int J Clin Lab Res 29 2 (1999) 49-55
44. Crouch R., Kimsey G., Priest D.G., Sarda A., and Buse M.G. Effect of streptozotocin on erythrocytes and retinal superoxide dismutase. Diabetologia 15 (1978) 53-57
45. Slater T.F. Free radical mediated mechanism in tissue injury. Biochem J 222 (1984) 1-15
46. Hayakawa M., and Kuzuya E. Free radicals and diabetes mellitus, Nippon Ronen Igakkau Zasshi-Japanese. J Geriatr 27 (1990) 149-204
47. Godin D.V., Wohaieb S.A., Garnetti M.E., and Goumenioule A.D. Antioxidants enzyme alterations in experimental clinical diabetes. Mol Cell Biochem 84 (1988) 278-280
48. Marklund S.L., Holme E., and Hellner L. Superoxide dismutase in extracellular fluids. Proc Natl Acad Sci U S A 79 (1982) 7634-7638
49. Uzel N., Sivas A., and Uysal M. Erythrocytes lipid peroxidation and glutathione peroxidase in patients with diabetes mellitus. Horm Metab Res 19 (1987) 89-90
50. Ndahinana J., Dorchy H., and Vertongen F. Erythrocyte and plasma antioxidant activity in diabetes mellitus type 1. Presse Med 25 (1996) 188-192
51. Faure P., Benhamou P.Y., Perard A., Halimi S., and Roussel A.M. Lipid peroxidation in insulin dependent diabetic patients with early retina degenerative lesions. Effect of an oral zinc supplementation. Eur J Clin Nutr 49 (1995) 282-288
52. Lang C.A., Wu W., Chen T., and Mills B.J. Blood glutathione: a biochemical index of life span enhancement in the diet restricted Lobund-Wistar rat. Prog Clin Biol Res 287 (1989) 241-246
53. Shan X.Q., and Jones D.P. Glutathione dependent protection against oxidative injury. Pharmacol Ther 47 (1990) 61-71