EPR studies on the superoxide-scavenging capacity of the nutraceutical resveratrol

Molecular and Cellular Biochemistry

Volumn 313, Issue 1-2, 2008, Pages 187-194

  Jia, Zhenquan ^a   Zhu, Hong ^a   Misra, Bhaba R ^a   Mahaney, James E ^a   Li, Yunbo ^a   Misra, Hara P ^a  

^a EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

Author keywords

EPR; Oxygen consumption; Resveratrol; Superoxide; Xanthine oxidase

Indexed keywords

5 DIETHOXYPHOSPHORYL 5 METHYL 1 PYRROLINE 1 OXIDE; NUTRACEUTICAL; RESVERATROL; SUPEROXIDE; URIC ACID; XANTHINE; XANTHINE OXIDASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME INHIBITION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; OXYGEN CONSUMPTION; SCAVENGING SYSTEM;

DIETARY SUPPLEMENTS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICAL SCAVENGERS; OXYGEN CONSUMPTION; PYRROLES; SPIN LABELS; STILBENES; SUPEROXIDES; URIC ACID; XANTHINE; XANTHINE OXIDASE;

MORUS(ANGIOSPERM); VITACEAE;

EID: 44449129847     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-008-9756-y     Document Type: Article

References (33)

1. Fremont L (2000) Biological effects of resveratrol. Life Sci 66:663-673
2. Bradamante S, Barenghi L, Villa A (2004) Cardiovascular protective effects of resveratrol. Cardiovasc Drug Rev 22:169-188
3. Gusman J, Malonne H, Atassi G (2001) A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol. Carcinogenesis 22:1111-1117
4. Virgili M, Contestabile A (2000) Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats. Neurosci Lett 281:123-126
5. Jang M, Pezzuto JM (1998) Effects of resveratrol on 12-O-tetradecanoylphorbol-13-acetate-induced oxidative events and gene expression in mouse skin. Cancer Lett 134:81-89
6. Cao Z, Li Y (2004) Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: Protection against oxidative and electrophilic injury. Eur J Pharmacol 489:39-48
7. Freeman BA, Crapo JD (1982) Biology of disease: Free radicals and tissue injury. Lab Invest 47:412-426
8. Fantone JC, Ward PA (1985) Polymorphonuclear leukocyte-mediated cell and tissue injury: Oxygen metabolites and their relations to human disease. Hum Pathol 16:973-978
9. Kong LD, Wolfender JL, Cheng CH, Hostettmann K, Tan RX (1999) Xanthine oxidase inhibitors from Brandisia hancei. Planta Med 65:744-746
10. Floyd RA (1990) Role of oxygen free radicals in carcinogenesis and brain ischemia. Faseb J 4:2587-2597
11. Shigematsu S, Ishida S, Hara M, Takahashi N, Yoshimatsu H, Sakata T, Korthuis RJ (2003) Resveratrol, a red wine constituent polyphenol, prevents superoxide-dependent inflammatory responses induced by ischemia/ reperfusion, platelet-activating factor, or oxidants. Free Radic Biol Med 34:810-817
12. Leonard SS, Xia C, Jiang BH, Stinefelt B, Klandorf H, Harris GK, Shi X (2003) Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochem Biophys Res Commun 309:1017-1026
13. Reiter CD, Teng RJ, Beckman JS (2000) Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite. J Biol Chem 275:32460-32466
14. Li Y, Kuppusamy P, Zweir JL, Trush MA (1996) Role of Cu/Zn-superoxide dismutase in xenobiotic activation II. Biological effects resulting from the Cu/Zn-superoxide dismutase-accelerated oxidation of the benzene metabolite 1,4-hydroquinone. Mol Pharmacol 49:412-421
15. Li Y, Zhu H, Kuppusamy P, Roubaud V, Zweier JL, Trush MA (1998) Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem 273:2015-2023
16. Fridovich I (1970) Quantitative aspects of the production of superoxide anion radical by milk xanthine oxidase. J Biol Chem 245:4053-4057
17. Frejaville C, Karoui H, Tuccio B, Le Moigne F, Culcasi M, Pietri S, Lauricella R, Tordo P (1995) 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide: A new efficient phosphorylated nitrone for the in vitro and in vivo spin trapping of oxygen-centered radicals. J Med Chem 38:258-265
18. Zweier JL (1988) Measurement of superoxide-derived free radicals in the reperfused heart. Evidence for a free radical mechanism of reperfusion injury. J Biol Chem 263:1353-1357
19. Wattanapitayakul SK, Bauer JA (2001) Oxidative pathways in cardiovascular disease: Roles, mechanisms, and therapeutic implications. Pharmacol Ther 89:187-206
20. Griendling KK, FitzGerald GA (2003) Oxidative stress and cardiovascular injAry: Part II: animal and human studies. Circulation 108:2034-2040
21. Molavi B, Mehta JL (2004) Oxidative stress in cardiovascular disease: molecular basis of its deleterious effects, its detection, and therapeutic considerations. Curr Opin Cardiol 19:488-493
22. Kehrer JP (1993) Free radicals as mediators of tissue injury and disease. Crit Rev Toxicol 23:21-48
23. Cai L, Kang YJ (2001) Oxidative stress and diabetic cardiomyopathy: A brief review. Cardiovasc Toxicol 1:181-193
24. Datta K, Sinha S, Chattopadhyay P (2000) Reactive oxygen species in health and disease. Natl Med J India 13:304-310
25. Storey KB (1996) Oxidative stress: Animal adaptations in nature. Braz J Med Biol Res 29:1715-1733
26. Das S, Falchi M, Bertelli A, Maulik N, Das DK (2006) Attenuation of ischemia/reperfusion injury in rats by the anti-inflammatory action of resveratrol. Arzneimittelforschung 56:700-706
27. Valentine JS, Curtis AB (1975) A convenient preparation of solutions of superoxide anion and the reaction of superoxide anion with a copper(II) complex. J Am Chem Soc 97:224-226
28. Timmins GS, Liu KJ, Bechara EJ, Kotake Y, Swartz HM (1999) Trapping of free radicals with direct in vivo EPR detection: A comparison of 5,5-dimethyl-1-pyrroline- N -oxide and 5-diethoxyphosphoryl-5-methyl-1-pyrroline- N -oxide as spin traps for HO* and SO4*. Free Radic Biol Med 27:329-333
29. Delmas-Beauvieux MC, Peuchant E, Thomas MJ, Dubourg L, Pinto AP, Clerc M, Gin H (1998) The place of electron spin resonance methods in the detection of oxidative stress in type 2 diabetes with poor glycemic control. Clin Biochem 31:221-228
30. Lubrano V, Di Cecco P, Zucchelli GC (2006) Role of superoxide dismutase in vascular inflammation and in coronary artery disease. Clin Exp Med 6:84-88
31. Darley-Usmar V, White R (1997) Disruption of vascular signalling by the reaction of nitric oxide with superoxide: Implications for cardiovascular disease. Exp Physiol 82:305-316
32. Heunks LM, Vina J, van Herwaarden CL, Folgering HT, Gimeno A, Dekhuijzen PN (1999) Xanthine oxidase is involved in exercise-induced oxidative stress in chronic obstructive pulmonary disease. Am J Physiol 277:R1697-R1704
33. Battelli MG, Musiani S, Valgimigli M, Gramantieri L, Tomassoni F, Bolondi L, Stirpe F (2001) Serum xanthine oxidase in human liver disease. Am J Gastroenterol 96:1194-1199