Intestinal and systemic immune development and response to vaccination are unaffected by dietary (1,3/1,6)-β-D-glucan supplementation in neonatal piglets

Clinical and Vaccine Immunology

Volumn 19, Issue 9, 2012, Pages 1499-1508

  Hester, Shelly N ^a   Comstock, Sarah S ^a   Thorum, Shannon C ^a   Monaco, Marcia H ^a   Pence, Brandt D ^a   Woods, Jeffrey A ^a   Donovana, Sharon M ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1,3 GLUCAN; BETA 1,6 GLUCAN; CYTOKINE; INFLUENZA VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; ASCENDING COLON; BODY WEIGHT; CELL PROLIFERATION; CONTROLLED STUDY; CRYPT CELL; CYTOKINE PRODUCTION; DIET SUPPLEMENTATION; GASTROINTESTINAL IMMUNE SYSTEM; ILEUM; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOLOGICAL PARAMETERS; INFLUENZA; INFLUENZA VACCINATION; INTESTINAL IMMUNE SYSTEM; INTESTINE MUCOSA; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGAN SIZE; ORGAN WEIGHT; ORGANOGENESIS; PHENOTYPE; PIGLET; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMALL INTESTINE; SYSTEMIC IMMUNE SYSTEM; T LYMPHOCYTE; TREATMENT OUTCOME; VACCINATION REACTION;

ANIMALS; ANIMALS, NEWBORN; BIOMETRY; BODY WEIGHT; CELL PROLIFERATION; CYTOKINES; DIET; GLUCANS; IMMUNOLOGIC FACTORS; INFLUENZA VACCINES; INTESTINES; SWINE; T-LYMPHOCYTES; VACCINATION;

EID: 84865976331     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00338-12     Document Type: Article

References (49)

1. Akramiene D, Kondrotas A, Didziapetriene J, Kevelaitis E. 2007. Effects of beta-glucans on the immune system. Medicina (Kaunas) 43:597-606.
2. Babicek K, Cechova I, Simon RR, Harwood M, Cox DJ. 2007. Toxicological assessment of a particulate yeast (1,3/1,6)-beta-D-glucan in rats. Food Chem. Toxicol. 45:1719-1730. (Pubitemid 47102509)
3. Baran J, Allendorf DJ, Hong F, Ross GD. 2007. Oral beta-glucan adjuvant therapy converts nonprotective Th2 response to protective Th1 cell-mediated immune response in mammary tumor-bearing mice. Folia Histochem. Cytobiol. 45:107-114. (Pubitemid 46939307)
4. Bauer E, Williams BA, Smidt H, Verstegen MW, Mosenthin R. 2006. Influence of the gastrointestinal microbiota on development of the immune system in young animals. Curr. Issues Intest. Microbiol. 7:35-51.
5. Blaschek W, Kasbauer J, Kraus J, Franz G. 1992. Pythium aphanidermatum: culture, cell-wall composition, and isolation and structure of antitumour storage and solubilised cell-wall (1-3),(1-6)-beta-D-glucans. Carbohydr. Res. 231:293-307.
6. Bogomolov SV, Zhirova SN, Kostinov MP. 2008. Cytokine profile and level of antibodies after administration of split-vaccine against influenza to adults. Zh. Mikrobiol. Epidemiol. Immunobiol. 5:57-61. (In Russian.)
7. Bohn JA, BJ. 1995. (1,3)-B-D-glucans as biological response modifiers: a review of structure-functional activity relationships. Carbohydr. Polym. 28:3.
8. Borca MV, Gudmundsdottir I, Fernandez-Sainz IJ, Holinka LG, Risatti GR. 2008. Patterns of cellular gene expression in swine macrophages infected with highly virulent classical swine fever virus strain Brescia. Virus Res. 138:89-96.
9. Bourne FJ. 1973. The immunoglobulin system of the suckling pig. Proc. Nutr. Soc. 32:205-215.
10. Collado-Romero M, Arce C, Ramirez-Boo M, Carvajal A, Garrido JJ. 2010. Quantitative analysis of the immune response upon Salmonella typhimurium infection along the porcine intestinal gut. Vet. Res. 41:23.
11. Cross GG, et al. 2001. Immunostimulant oxidized beta-glucan conjugates. Int. Immunopharmacol. 1:539-550.
12. Decuypere J, Dierick N, Boddez S. 1998. The potentials for immunostimulatory substances (B-1,3/1,6-glucans) in pig nutrition. J. Anim. Feed Sci. 7(Suppl. 1):259.
13. Descroix K, Ferrieres V, Jamois F, Yvin JC, Plusquellec D. 2006. Recent progress in the field of beta-(1,3)-glucans and new applications. Mini Rev. Med. Chem. 6:1341-1349. (Pubitemid 44890541)
14. Desselberger U, et al. 2009. Rotaviruses and rotavirus vaccines. Br. Med. Bull. 90:37-51.
15. Fabre I, Bruneteau M, Ricci P, Michel G. 1984. Isolation and structural studies of glucans from Phytophthora parasitica. Eur. J. Biochem. 142:99-103.
16. Goodridge HS, Wolf AJ, Underhill DM. 2009. Beta-glucan recognition by the innate immune system. Immunol. Rev. 230:38-50.
17. Hahn TW, Lohakare JD, Lee SL, Moon WK, Chae BJ. 2006. Effects of supplementation of beta-glucans on growth performance, nutrient digestibility, and immunity in weanling pigs. J. Anim. Sci. 84:1422-1428. (Pubitemid 43844894)
18. Helgeland L, Vaage JT, Rolstad B, Midtvedt T, Brandtzaeg P. 1996. Microbial colonization influences composition and T-cell receptor V beta repertoire of intraepithelial lymphocytes in rat intestine. Immunology. 89:494-501. (Pubitemid 26419648)
19. Hiss S, Sauerwein H. 2003. Influence of dietary ss-glucan on growth performance, lymphocyte proliferation, specific immune response and haptoglobin plasma concentrations in pigs. J. Anim. Physiol. Anim. Nutr. (Berl.) 87:2-11. (Pubitemid 36280833)
20. Jung K, et al. 2004. Antiviral effect of Saccharomyces cerevisiae betaglucan to swine influenza virus by increased production of interferon-gamma and nitric oxide. J. Vet. Med. B Infect. Dis. Vet. Public Health 51:72-76. (Pubitemid 38484946)
21. Kaplan JL, Shi HN, Walker WA. 2011. The role of microbes in developmental immunologic programming. Pediatr. Res. 69:465-472.
22. Kelly D, Coutts AG. 2000. Early nutrition and the development of immune function in the neonate. Proc. Nutr. Soc. 59:177-185. (Pubitemid 30604737)
23. Kelly D, King T, Aminov R. 2007. Importance of microbial colonization of the gut in early life to the development of immunity. Mutat. Res. 622: 58-69. (Pubitemid 47211174)
24. Keylock KT, et al. 2007. Higher antibody, but not cell-mediated, responses to vaccination in high physically fit elderly. J. Appl. Physiol. 102: 1090-1098. (Pubitemid 46377036)
25. Kojima T, Tabata K, Itoh W, Yanaki T. 1986. Molecular weight dependence of the antitumor activity of schizophyllan. Agric. Biol. Chem. 50:231.
26. Kournikakis B, Mandeville R, Brousseau P, Ostroff G. 2003. Anthrax-protective effects of yeast beta 1,3 glucans. MedGenMed 5:1.
27. Lalor MK, et al. 2010. Complex cytokine profiles induced by BCG vaccination in UK infants. Vaccine 28:1635-1641.
28. Li J, et al. 2005. Effects of beta-glucan extracted from Saccharomyces cerevisiae on humoral and cellular immunity in weaned piglets. Arch. Anim. Nutr. 59:303-312. (Pubitemid 43205606)
29. Mueller A, et al. 2000. The influence of glucan polymer structure and solution conformation on binding to (1→3)-beta-D-glucan receptors in a human monocyte-like cell line. Glycobiology 10:339-346. (Pubitemid 30184604)
30. Nygard AB, Jorgensen CB, Cirera S, Fredholm M. 2007. Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR. BMC Mol. Biol. 8:67.
31. Ogra SS, Weintraub D, Ogra PL. 1977. Immunologic aspects of human colostrum and milk. III. Fate and absorption of cellular and soluble components in the gastrointestinal tract of the newborn. J. Immunol. 119:245-248. (Pubitemid 8141146)
32. Pabst HF, Spady DW. 1990. Effect of breast-feeding on antibody response to conjugate vaccine. Lancet 336:269-270. (Pubitemid 20229122)
33. Pence BD, Hester SN, Donovan SM, Woods JA. 2012. Dietary whole glucan particles do not affect antibody or cell-mediated immune responses to influenza virus vaccination in mice. Immunol. Invest. 41:275-289.
34. Pickering LK, et al. 1998. Modulation of the immune system by human milk and infant formula containing nucleotides. Pediatrics. 101:242-249. (Pubitemid 28076657)
35. Price KL, et al. 2010. Use of Saccharomyces cerevisiae fermentation product on growth performance and microbiota of weaned pigs during Salmonella infection. J. Anim. Sci. 88:3896-3908.
36. Sabirov A, Casey JR, Murphy TF, Pichichero ME. 2009. Breast-feeding is associated with a reduced frequency of acute otitis media and high serum antibody levels against NTHi and outer membrane protein vaccine antigen candidate P6. Pediatr. Res. 66:565-570.
37. Saito H, et al. 1991. Relationship between conformation and biological response for (1-3)-beta-D-glucans in the activation of coagulation factor G from limulus amebocyte lysate and host-mediated antitumor activity. Demonstration of single-helix conformation as a stimulant. Carbohydr. Res. 217:181-190.
38. Schaller JP, et al. 2004. Effect of dietary ribonucleotides on infant immune status. Part 1. Humoral responses. Pediatr. Res. 56:883-890. (Pubitemid 39552769)
39. Seijelid R, Bogwald J, Lundwall A. 1981. Glycan stimulation of macrophages in vitro. Exp. Cell Res. 131:121.
40. Sonck E, Stuyven E, Goddeeris B, Cox E. 2009. Identification of the porcine C-type lectin dectin-1. Vet. Immunol. Immunopathol. 130:131-134.
41. Sonck E, Stuyven E, Goddeeris B, Cox E. 2010. The effect of beta-glucans on porcine leukocytes. Vet. Immunol. Immunopathol. 135:199-207.
42. Stuyven E, et al. 2009. Effect of beta-glucans on an ETEC infection in piglets. Vet. Immunol. Immunopathol. 128:60-66.
43. Stuyven E, Van den Broeck W, Nauwynck H, Goddeeris BM, Cox E. 2010. Oral administration of beta-1,3/1,6-glucan Macrogard fails to enhance the mucosal immune response following oral F4 fimbrial immunisation in gnotobiotic pigs. Vet. Immunol. Immunopathol. 137:291-297.
44. Suzuki I, Hashimoto K, Ohno N, Tanaka H, Yadomae T. 1989. Immunomodulation by orally administered beta-glucan in mice. Int. J. Immunopharmacol. 11:761-769. (Pubitemid 19252363)
45. Takemae N, et al. 2011. Swine influenza virus infection in different age groups of pigs in farrow-to-finish farms in Thailand. Virol. J. 8:537.
46. Willment JA, Gordon S, Brown GD. 2001. Characterization of the human beta-glucan receptor and its alternatively spliced isoforms. J. Biol. Chem. 276:43818-43823.
47. Xiao Z, Trincado CA, Murtaugh MP. 2004. Beta-glucan enhancement of T cell IFNgamma response in swine. Vet. Immunol. Immunopathol. 102: 315-320. (Pubitemid 39422653)
48. Zanetti M. 1992. Ontogeny of the immune system and the invisible frontier to immune regulation. Int. Rev. Immunol. 8:209-218.
49. Zuckermann FA, Husmann RJ. 1996. Functional and phenotypic analysis of porcine peripheral blood CD4/CD8 double-positive T cells. Immunology 87:500-512. (Pubitemid 26100194)