Modulation of the immune system by human milk and infant formula containing nucleotides

Pediatrics

Volumn 101, Issue 2, 1998, Pages 242-249

  Pickering, Larry K ^a,e   Granoff, Dan M ^b   Erickson, Julie Reed ^c   Masor, Marc L ^d   Cordle, Christopher T ^d   Schaller, Joseph P ^d   Winship, Timothy R ^d   Paule, Charles L ^d   Hilty, Milo D ^d  

^a CHILDREN S HOSPITAL OF THE KING S DAUGHTERS   (United States)

^b CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d ABBOTT LABORATORIES   (United States)

^e CENTER FOR PEDIATRIC RESEARCH   (United States)

Author keywords

Antibody; Breast milk; Diphtheria; H influenzae b; Human milk; Immune development; Immune response; Infant formula; Nucleotides; Polio; Vaccine response

Indexed keywords

DIPHTHERIA TOXOID; DIPHTHERIA VACCINE; HAEMOPHILUS INFLUENZAE TYPE B VACCINE; NUCLEOTIDE; ORAL POLIOMYELITIS VACCINE;

ANTIBODY RESPONSE; ARTICLE; ARTIFICIAL MILK; BOTTLE FEEDING; BREAST FEEDING; BREAST MILK; CLINICAL TRIAL; CONTROLLED STUDY; DIPHTHERIA; FEMALE; HAEMOPHILUS INFLUENZAE TYPE B; HUMAN; HUMAN EXPERIMENT; IMMUNIZATION; IMMUNOMODULATION; IMMUNOREACTIVITY; MALE; NEWBORN; NORMAL HUMAN; POLIOMYELITIS; PRIORITY JOURNAL;

BOTTLE FEEDING; BREAST FEEDING; FOOD, FORTIFIED; HUMANS; IMMUNE SYSTEM; IMMUNOGLOBULINS; INFANT; INFANT FOOD; INFANT, NEWBORN; MILK, HUMAN; NUCLEOTIDES; SINGLE-BLIND METHOD; VACCINES;

EID: 0031908146     PISSN: 00314005     EISSN: None     Source Type: Journal    
DOI: 10.1542/peds.101.2.242     Document Type: Article

References (58)

1. Dewey KG, Heinig MJ, Nommsen-Rivers LA. Differences in morbidity between breast-fed and formula-fed infants. J Pediatr. 1995;126:696-702
2. Pickering LK, Morrow AL. Factors in human milk that protect against diarrhea disease. Infection. 1993;21:355-357
3. Feachem RG, Koblinsky MA. Interventions for the control of diarrhoeal diseases among young children: promotion of breastfeeding. Bull World Health Organ. 1984;62:271-291
4. Glass RI, Svennerholm A, Stoll BJ, et al. Milk antibodies protect breast-fed children against cholera. N Engl J Med. 1983;30:1389-1392
5. Ruiz-Palacios GM, Calva JJ, Pickering LK, et al. Protection of breastfed infants against Campylobacter diarrhea by antibodies in human milk. Pediatrics. 1990;116:707-713
6. Cravioto A, Tello A, Villafan H, Ruiz J, del Vedova S, Neeser JR. Inhibition of localized adhesion of enteropathogenic Escherichia coli to HEp-2 cells by immunoglobulin and oligosaccharide fractions of human colostrum and breast milk. J Infect Dis. 1991;163:1247-1255
7. Cruz CR, Gil L, Cano F, Caceres P, Pareja G. Breast milk anti-Escherichia coli heat-labile toxin IgA antibodies protect against toxin induced infantile diarrhea. Acta Paediatr Scand. 1988;77:658-662
8. Hayani KC, Guerrero ML, Morrow AL, et al. Concentration of milk secretory immunoglobulin A against Shigella virulence plasmid-associated antigens as a predictor of symptom status in Shigella-infected breastfed infants. Pediatrics. 1992;121:852-856
9. Miotti PG, Gilman RH, Pickering LK, Ruiz-Palacios G, Park HS, Yolken RH. Prevalence of serum and milk antibodies to Giardia lamblia in different populations of lactating women. J Infect Dis. 1985;152: 1025-1031
10. Walterspiel JN, Morrow AL, Guerrero NM, Ruiz-Palacios GM, Pickering LK. Protective effect of secretary anti-Giardia lamblia antibodies in human milk against diarrhea. Pediatrics. 1994;93:28-31
11. Costa-Carvalho BT, Bertipaglia A, Solé D, Naspitz CK, Scaletsky KA. Detection of immunoglobulin (IgG and IgA) anti-outer-membrane proteins of enteropathogenic Escherichia coli (EPEC) in saliva, colostrum, breast milk, serum, cord blood and amniotic fluid. Study of inhibition of localized adherence of EPEC to HeLa cells. Acta Paediatr. 1994;83: 870-873
12. Newburg DS, Pickering LK, McCluer RH, Cleary TG. Fucosylated oligosaccharides of human milk protect suckling mice from heat-stable enterotoxin of Escherichia coli. J Infect Dis. 1990;162:1075-1080
13. Newburg DS, Ashkenazi S, Cleary TG. Human milk contains the Shiga toxin and Shigalike toxin receptor glycolipid Gb3. J Infect Dis. 1992;166: 832-836
14. Yolken RH, Peterson JA, Vonderfecht SL, et al. Human milk mucin inhibits rotavirus replication and prevents experimental gastroenteritis. J Clin Invest. 1992;90:1984-1991
15. Chiba Y, Minagawa T, Mito K, et al. Effect of breast-feeding on responses of systemic interferon and virus-specific lymphocyte transformation in infants with respiratory syncytial infection. J Med Virol. 1987;21:7-14
16. Pabst HF, Spady DW. Effect of breast-feeding on antibody response to conjugate vaccines. Lancet. 1990;336:269-270
17. Hahn-Zoric M, Fulconis F, Minoli I, et al. Antibody responses to parenteral and oral vaccines are impaired by conventional and low protein formula as compared to breastfeeding. Acta Paediatr Scand. 1990;79: 1137-1142
18. Carver JD, Pimentel B, Cox WI, Barness LA. Dietary nucleotide effects upon immune function in infants. Pediatrics. 1991;88:359-363
19. Pelton SI, Barnett ED, Cabrai HJ, Klein JO. Lymphocyte phenotypes in breast and formula fed infants; potential implication for regulation of response to Haemophilus polysaccharide conjugate vaccine (HCV). ICAAC Abstracts. 1995;G55:168
20. Fitzsimmons SP, Evans MK, Pearce CL, Sheridan MJ, Wientzen R, Cole MF. Immunoglobulin A subclasses in infants' saliva and in saliva and milk from their mothers. J Pediatr. 1994;124:566-573
21. Stephens S, Brenner MK, Duffy SW, Lakhani PK, Kennedy CR, Farrant J. The effect of breast-feeding on proliferation by infant lymphocytes in vitro. Pediatr Res. 1986;20:227-231
22. Kulkarni SS, Bhateley DC, Zander AR, et al. Functional impairment of T-lymphocytes in mouse radiation chimeras by a nucleotide-free diet. Exp Hematol 1984;12:694-699
23. Van Buren CT, Kulkarni AD, Schandle VB, Rudolph FB. The influence of dietary nucleotides on cell-mediated immunity. Transplantation. 1983b;36:350-352
24. Kulkarni AD, Fanslow WC, Rudolph FB, Van Buren CT. Modulation of delayed hypersensirivity in mice by dietary nucleotide restriction. Transplantation. 1987;44:847-849
25. Pizzini RP, Kumar S, Kulkarni AD, Rudolph FB, VanBuren CT. Dietary nucleotides reverse malnutrition and starvation-induced immunosuppression. Arch Surg. 1990;125:86-90
26. Kulkarni AD, Fanslow WC, Rudolph FB, Van Buren CT. Effect of dietary nucleotides on response to bacterial infections. JPEN. 1986b;10: 169-171
27. Fanslow WC, Kulkarni AD, Van Buren CT, Rudolph FB. Effect of nucleotide restriction and supplementation on resistance to experimental candidiasis. JPEN. 1988;12:49-52
28. Van Buren CT, Kulkarni AD, Fanslow WC, Rudolph FB. Dietary nucleotides, a requirement for helper/inducer T lymphocytes. Transplantation. 1985;40:694-697
29. Kulkarni A, Fanslow W, Higley H, Pizzini R, Rudolph F, Van Buren C. Expression of immune cell surface markers in vivo and immune competence in mice by dietary nucleotides. Transplant Proc. 1989;21:121-124
30. Rudolph FB, Kukarni AD, Schandle VB, Van Buren CT. Involvement of dietary nucleotides in T lymphocyte function. Adv Exp Med. 1984;165: 175-178
31. Rudolph FB, Fanslow WC, Kulkarni AD, Kulkarni SS, VanBuren CT. Effect of dietary nucleotides on lymphocyte maturation. Adv Exp Med Biol. 1986;195A:497-501
32. Jyonouchi H, Zhang-Shanbhag L, Tomita Y, Yokoyama H. Nucleotide-free diet impairs T-helper cell functions in antibody production in response to T-dependent antigens in normal C57B1/6 mice. J Nutr. 1994;124:475-484
33. Uauy R, Stringel G, Thomas R, et al. Effect of dietary nucleoside on growth and maturation of the developing gut in the rat. J Pediatr Gastroenterol Nutr. 1990;10:497-503
34. Carver J, Bustamante S, Novak D, Barness L. Dietary nucleoside may act as growth factors in liver and intestine. FASEB J. 1993;4:A643
35. Bueno J, Torres M, Almendros A, et al. Effect of dietary nucleotides on small intestinal repair after diarrhoea. Histological and ultrastructural changes. Gut. 1994;35:926-933
36. Ogoshi S, Mizobuchi S, Iwasa M, Tamlya T. Effect of a nucleoside-nucleotide mixture on protein metabolism in rats after seventy percent hepatectomy. Nutrition. 1989;5:173-178
37. Brunser O, Espinoza J, Araya M, Cruchet S, Gil A. Effect of dietary nucleotide supplementation on diarrhoeal disease in infants. Acta Paediatr Scand. 1994;83:188-191
38. Janas LM, Picciano MF. The nucleotide profile of human milk. Pediatr Res. 1982;16:659-662
39. Gil A, Uauy R. Nucleotides and related compounds in human and bovine milks. In: Jensen RG, ed: Handbook of Milk Composition. San Diego, CA: Academic Press; 1995:436-464
40. Wheeler JG, Steiner D. Evaluation of humoral responsiveness in children. Pediatr Infect Dis J. 1992;11:304-310
41. Leach JL, Baxter JH, Molitor BE, Ramstack MD, Masor ML. Total potentially available nucleosides of human milk by stage of lactation. Am J Clin Nutr. 1995;61:1224-1230
42. Committee on Infectious Diseases. Report on the Committee on Infectious Diseases. 22nd ed. Elk Grove Village, IL: American Academy of Pediatrics; 1991
43. Fahey JL, McKelvey EM. Quantitative determination of serum immunoglobulins in antibody-agar plates. J Immunol. 1965;94:84-90
44. Mancini G, Carbonara AO, Heremans JF. Immunochemical quantitation of antigens by single radial immunodiffusion. Int J Imnnmochem. 1965; 2:235-254
45. Hamilton RH. Human IgG subclass measurements in the clinical laboratory. Clin Chem. 1987;33:1707-1725
46. Sedgwick AK, Ballow M, Sparks K, Tilton RC. Rapid quantitative microenzyme-linked immunosorbent assay for tetanus antibodies. J Clin Microbiol. 1983;18:104-109
47. Granoff DM, Holmes SJ, Belshe RB, et al. Effect of carrier protein priming on antibody responses to Haemophilus influenzae type b conjugate vaccines in infants. JAMA. 1994;272:1116-1121
48. Granoff DM, Holmes SJ, Osterholm MT, et al. Induction of immunologic memory in infants primed with Haemophilus influenzae type b conjugate vaccines. J Infect Dis. 1993;168:663-671
49. Gruss AD, Spier-Michl IB, Gotschlich EC. A method for a radioimmunoassay using microtiter plates allowing simultaneous determination of antibodies to two non crossreactive antigens. Immunochemistry. 1978;15: 777-780
50. Faden H, Modlin JF, Thorns ML, McBean AM, Ogra PL. Comparative evaluation of immunization with live attenuated and enhanced-potency inactivated trivalent poliovirus vaccines in childhood: systemic and local immune responses. J Infect Dis. 1990;162:1291-1297
51. Albrecht P, van Steenis G, van Wezel AL, Salk J. Standardization of poliovirus neutralizing antibody tests. Rev Infect Dis. 1984;6(suppl): S540-S544
52. Amir J, Scott MG, Nahm MH, Granoff DM. Bactericidal and opsonic activity of IgG1 and IgG2 anticapsular antibodies to Haemophilus influenzae type b. J Infect Dis. 1990;162:163-171
53. Lucas AH, Granoff DM. Functional differences in idiotypically defined IgG1 anti-polysaccharide antibodies elicited by vaccination with Haemophilus influenzae type b polysaccharide-protein conjugates. J Immunol. 1995;154:4195-4202
54. Käyhry H, Peltola H, Karanko V, Mäkelä PH. The protective level of serum antibodies to the capsular polysaccharide of Haemophilus influenzae type b. J Infect Dis. 1993;147:1100
55. Wilson CB. Developmental immunology and role of host defenses in neonatal susceptibility. In: Lamsback W, ed. Infectious Diseases of the Fetus and Newborn Infants. Philadelphia, PA: WB Saunders Co; 1990: 17-67
56. Carver JD, Walker WA. The role of nucleotides in human nutrition. Nutritional Biochemistry. 1995;6:58-72
57. World Health Organization Collaborative Study Group on Oral Polio-virus Vaccine. Factors affecting the immunogenicity of oral poliovirus vaccine: a prospective evaluation in Brazil and the Gambia. J Infect Dis. 1995;171:1097-1106
58. Scheifele D, Bjornson GJ, Guasparini R, Friesen B, Meekison W. Breast-feeding and antibody responses to routine vaccination in infants. Lancet. 1992;340:1406.