메뉴 건너뛰기




Volumn 109, Issue 36, 2012, Pages 14526-14531

A vaccine directed to B cells and produced by cell-free protein synthesis generates potent antilymphoma immunity

Author keywords

Bispecific antibody fragments; Immunotherapy; Tumor speci fic antigen

Indexed keywords

ALPHA CD19 IDIOTYPE; CANCER VACCINE; CD19 ANTIBODY; UNCLASSIFIED DRUG;

EID: 84865975048     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1211018109     Document Type: Article
Times cited : (41)

References (42)
  • 1
    • 0032529703 scopus 로고    scopus 로고
    • Anti-idiotype antibodies can induce long-term complete remissions in non-Hodgkin's lymphoma without eradicating the malignant clone
    • Davis TA, Maloney DG, Czerwinski DK, Liles TM, Levy R (1998) Anti-idiotype antibodies can induce long-term complete remissions in non-Hodgkin's lymphoma without eradicating the malignant clone. Blood 92:1184-1190. (Pubitemid 28369031)
    • (1998) Blood , vol.92 , Issue.4 , pp. 1184-1190
    • Davis, T.A.1    Maloney, D.G.2    Czerwinski, D.K.3    Liles, T.-M.4    Levy, R.5
  • 2
    • 14544301233 scopus 로고    scopus 로고
    • Clinical outcome of lymphoma patients after idiotype vaccination is correlated with humoral immune response and immunoglobulin G Fc receptor genotype
    • Weng WK, Czerwinski D, Timmerman J, Hsu FJ, Levy R (2004) Clinical outcome of lymphoma patients after idiotype vaccination is correlated with humoral immune response and immunoglobulin G Fc receptor genotype. J Clin Oncol 22:4717-4724.
    • (2004) J Clin Oncol , vol.22 , pp. 4717-4724
    • Weng, W.K.1    Czerwinski, D.2    Timmerman, J.3    Hsu, F.J.4    Levy, R.5
  • 3
    • 67651100890 scopus 로고    scopus 로고
    • Anti-idiotype antibody response after vaccination correlates with better overall survival in follicular lymphoma
    • Ai WZ, Tibshirani R, Taidi B, Czerwinski D, Levy R (2009) Anti-idiotype antibody response after vaccination correlates with better overall survival in follicular lymphoma. Blood 113:5743-5746.
    • (2009) Blood , vol.113 , pp. 5743-5746
    • Ai, W.Z.1    Tibshirani, R.2    Taidi, B.3    Czerwinski, D.4    Levy, R.5
  • 4
    • 79551649969 scopus 로고    scopus 로고
    • Upfront immunization with autologous recombinant idiotype Fab fragment without prior cytoreduction in indolent B-cell lymphoma
    • Navarrete MA, et al. (2011) Upfront immunization with autologous recombinant idiotype Fab fragment without prior cytoreduction in indolent B-cell lymphoma. Blood 117:1483-1491.
    • (2011) Blood , vol.117 , pp. 1483-1491
    • Navarrete, M.A.1
  • 5
    • 54249138398 scopus 로고    scopus 로고
    • Results of a phase 3 trial evaluating safety and efficacy of specific immunotherapy, recombinant idiotype (Id) conjugated to KLH (Id-KLH) with GM-CSF, compared to non-specific immunotherapy, KLH with GM-CSF, in patients with follicular non Hodgkin's lymphoma (FNHL)
    • Levy R, Robertson M, Leonard J, Vose J, Danney D (2008) Results of a phase 3 trial evaluating safety and efficacy of specific immunotherapy, recombinant idiotype (Id) conjugated to KLH (Id-KLH) with GM-CSF, compared to non-specific immunotherapy, KLH with GM-CSF, in patients with follicular non Hodgkin's lymphoma (FNHL). Ann Oncol 19(suppl 4):101-102.
    • (2008) Ann Oncol , vol.19 , Issue.SUPPL. 4 , pp. 101-102
    • Levy, R.1    Robertson, M.2    Leonard, J.3    Vose, J.4    Danney, D.5
  • 6
    • 67649961713 scopus 로고    scopus 로고
    • Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma
    • Freedman A, et al. (2009) Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma. J Clin Oncol 27: 3036-3043.
    • (2009) J Clin Oncol , vol.27 , pp. 3036-3043
    • Freedman, A.1
  • 7
    • 79958264390 scopus 로고    scopus 로고
    • Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma
    • Schuster SJ, et al. (2011) Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma. J Clin Oncol 29: 2787-2794.
    • (2011) J Clin Oncol , vol.29 , pp. 2787-2794
    • Schuster, S.J.1
  • 8
    • 56149108713 scopus 로고    scopus 로고
    • Sulfhydryl-based tumor antigen-carrier protein conjugates stimulate superior antitumor immunity against B cell lymphomas
    • Betting DJ, Kafi K, Abdollahi-Fard A, Hurvitz SA, Timmerman JM (2008) Sulfhydryl-based tumor antigen-carrier protein conjugates stimulate superior antitumor immunity against B cell lymphomas. J Immunol 181:4131-4140.
    • (2008) J Immunol , vol.181 , pp. 4131-4140
    • Betting, D.J.1    Kafi, K.2    Abdollahi-Fard, A.3    Hurvitz, S.A.4    Timmerman, J.M.5
  • 9
    • 34447623566 scopus 로고    scopus 로고
    • B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node
    • Carrasco YR, Batista FD (2007) B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node. Immunity 27:160- 171.
    • (2007) Immunity , vol.27 , pp. 160-171
    • Carrasco, Y.R.1    Batista, F.D.2
  • 10
    • 34548044827 scopus 로고    scopus 로고
    • Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells
    • DOI 10.1038/ni1494, PII NI1494
    • Phan TG, Grigorova I, Okada T, Cyster JG (2007) Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells. Nat Immunol 8:992-1000. (Pubitemid 47300014)
    • (2007) Nature Immunology , vol.8 , Issue.9 , pp. 992-1000
    • Phan, T.G.1    Grigorova, I.2    Okada, T.3    Cyster, J.G.4
  • 11
    • 67649221652 scopus 로고    scopus 로고
    • Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
    • Phan TG, Green JA, Gray EE, Xu Y, Cyster JG (2009) Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. Nat Immunol 10:786-793.
    • (2009) Nat Immunol , vol.10 , pp. 786-793
    • Phan, T.G.1    Green, J.A.2    Gray, E.E.3    Xu, Y.4    Cyster, J.G.5
  • 12
    • 5044252309 scopus 로고    scopus 로고
    • Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells
    • DOI 10.1093/intimm/dxh142
    • Ferguson AR, Youd ME, Corley RB (2004) Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells. Int Immunol 16: 1411-1422. (Pubitemid 39341554)
    • (2004) International Immunology , vol.16 , Issue.10 , pp. 1411-1422
    • Ferguson, A.R.1    Youd, M.E.2    Corley, R.B.3
  • 13
    • 0034693949 scopus 로고    scopus 로고
    • Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex
    • Gretz JE, Norbury CC, Anderson AO, Proudfoot AE, Shaw S (2000) Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex. J Exp Med 192:1425-1440.
    • (2000) J Exp Med , vol.192 , pp. 1425-1440
    • Gretz, J.E.1    Norbury, C.C.2    Anderson, A.O.3    Proudfoot, A.E.4    Shaw, S.5
  • 14
    • 60149086845 scopus 로고    scopus 로고
    • Conduits mediate transport of low-molecular-weight antigen to lymph node follicles
    • Roozendaal R, et al. (2009) Conduits mediate transport of low-molecular-weight antigen to lymph node follicles. Immunity 30:264-276.
    • (2009) Immunity , vol.30 , pp. 264-276
    • Roozendaal, R.1
  • 15
    • 0034097043 scopus 로고    scopus 로고
    • Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex
    • DOI 10.1146/annurev.immunol.18.1.393
    • Fearon DT, Carroll MC (2000) Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex. Annu Rev Immunol 18:393-422. (Pubitemid 30365386)
    • (2000) Annual Review of Immunology , vol.18 , pp. 393-422
    • Fearon, D.T.1    Carroll, M.C.2
  • 16
    • 38449099301 scopus 로고    scopus 로고
    • Development of cell-free protein synthesis platforms for disulfide bonded proteins
    • DOI 10.1002/bit.21567
    • Goerke AR, Swartz JR (2008) Development of cell-free protein synthesis platforms for disulfide bonded proteins. Biotechnol Bioeng 99:351-367. (Pubitemid 351158284)
    • (2008) Biotechnology and Bioengineering , vol.99 , Issue.2 , pp. 351-367
    • Goerke, A.R.1    Swartz, J.R.2
  • 17
    • 34147092704 scopus 로고    scopus 로고
    • Cell-free production of scFv fusion proteins: An efficient approach for personalized lymphoma vaccines
    • DOI 10.1182/blood-2006-07-030593
    • Kanter G, et al. (2007) Cell-free production of scFv fusion proteins: an efficient approach for personalized lymphoma vaccines. Blood 109:3393-3399. (Pubitemid 46572528)
    • (2007) Blood , vol.109 , Issue.8 , pp. 3393-3399
    • Kanter, G.1    Yang, J.2    Voloshin, A.3    Levy, S.4    Swartz, J.R.5    Levy, R.6
  • 19
    • 0027315755 scopus 로고
    • Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma
    • Tao MH, Levy R (1993) Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma. Nature 362:755-758.
    • (1993) Nature , vol.362 , pp. 755-758
    • Tao, M.H.1    Levy, R.2
  • 20
    • 0029845387 scopus 로고    scopus 로고
    • DNA immunization induces protective immunity against B-cell lymphoma
    • DOI 10.1038/nm0996-1038
    • Syrengelas AD, Chen TT, Levy R (1996) DNA immunization induces protective immunity against B-cell lymphoma. Nat Med 2:1038-1041. (Pubitemid 26306846)
    • (1996) Nature Medicine , vol.2 , Issue.9 , pp. 1038-1041
    • Syrengelas, A.D.1    Chen, T.T.2    Levy, R.3
  • 22
    • 0032998424 scopus 로고    scopus 로고
    • Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity
    • DOI 10.1038/6995
    • Biragyn A, Tani K, Grimm MC, Weeks S, Kwak LW (1999) Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity. Nat Biotechnol 17:253-258. (Pubitemid 29122633)
    • (1999) Nature Biotechnology , vol.17 , Issue.3 , pp. 253-258
    • Biragyn, A.1    Tani, K.2    Grimm, M.C.3    Weeks, S.4    Kwak, L.W.5
  • 23
    • 34548821867 scopus 로고    scopus 로고
    • Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences
    • DOI 10.1182/blood-2006-06-032938
    • Fredriksen AB, Bogen B (2007) Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences. Blood 110:1797-1805. (Pubitemid 47443890)
    • (2007) Blood , vol.110 , Issue.6 , pp. 1797-1805
    • Fredriksen, A.B.1    Bogen, B.2
  • 24
    • 4644274938 scopus 로고    scopus 로고
    • Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo
    • DOI 10.1182/blood-2004-02-0637
    • Biragyn A, et al. (2004) Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo. Blood 104:1961-1969. (Pubitemid 39297844)
    • (2004) Blood , vol.104 , Issue.7 , pp. 1961-1969
    • Biragyn, A.1    Ruffini, P.A.2    Coscia, M.3    Harvey, L.K.4    Neelapu, S.S.5    Baskar, S.6    Wang, J.-M.7    Kwak, L.W.8
  • 25
  • 26
    • 0030593030 scopus 로고    scopus 로고
    • C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
    • Dempsey PW, Allison ME, Akkaraju S, Goodnow CC, Fearon DT (1996) C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity. Science 271:348-350.
    • (1996) Science , vol.271 , pp. 348-350
    • Dempsey, P.W.1    Allison, M.E.2    Akkaraju, S.3    Goodnow, C.C.4    Fearon, D.T.5
  • 27
    • 0031954004 scopus 로고    scopus 로고
    • Enhanced molecular mimicry of CEA using photoaffinity crosslinked C3d peptide
    • DOI 10.1038/nbt0598-458
    • Lou D, Kohler H (1998) Enhanced molecular mimicry of CEA using photoaffinity crosslinked C3d peptide. Nat Biotechnol 16:458-462. (Pubitemid 28211199)
    • (1998) Nature Biotechnology , vol.16 , Issue.5 , pp. 458-462
    • Lou, D.1    Kohler, H.2
  • 28
    • 0034804363 scopus 로고    scopus 로고
    • Fusion of C3d molecule with bovine rotavirus VP7 or bovine herpesvirus type 1 glycoprotein D inhibits immune responses following DNA immunization
    • DOI 10.1016/S0165-2427(01)00369-5, PII S0165242701003695
    • Suradhat S, et al. (2001) Fusion of C3d molecule with bovine rotavirus VP7 or bovine herpesvirus type 1 glycoprotein D inhibits immune responses following DNA immunization. Vet Immunol Immunopathol 83:79-92. (Pubitemid 32927187)
    • (2001) Veterinary Immunology and Immunopathology , vol.83 , Issue.1-2 , pp. 79-92
    • Suradhat, S.1    Braun, R.P.2    Lewis, P.J.3    Babiuk, L.A.4    Griebel, P.J.5    Baca-Estrada, M.E.6
  • 29
    • 27744568318 scopus 로고    scopus 로고
    • Genetic fusion of three tandem copies of murine C3d sequences to diphtheria toxin fragment B elicits a decreased fragment B-specific antibody response
    • DOI 10.1016/j.imlet.2005.06.020, PII S0165247805001549
    • Gor DO, Ding X, Li Q, Greenspan NS (2006) Genetic fusion of three tandem copies of murine C3d sequences to diphtheria toxin fragment B elicits a decreased fragment B-specific antibody response. Immunol Lett 102:38-49. (Pubitemid 41606038)
    • (2006) Immunology Letters , vol.102 , Issue.1 , pp. 38-49
    • Gor, D.O.1    Ding, X.2    Li, Q.3    Greenspan, N.S.4
  • 30
    • 0027511485 scopus 로고
    • Antibody-induced modulation and intracellular transport of CD10 and CD19 antigens in human B-cell lines: An immunofluorescence and immunoelectron microscopy study
    • Pulczynski S, Boesen AM, Jensen OM (1993) Antibody-induced modulation and intracellular transport of CD10 and CD19 antigens in human B-cell lines: An immunofluorescence and immunoelectron microscopy study. Blood 81:1549-1557. (Pubitemid 23083834)
    • (1993) Blood , vol.81 , Issue.6 , pp. 1549-1557
    • Pulczynski, S.1    Boesen, A.M.2    Jensen, O.M.3
  • 31
    • 51049120495 scopus 로고    scopus 로고
    • Differential cellular internalization of anti-CD19 and -CD22 immunotoxins results in different cytotoxic activity
    • Du X, Beers R, Fitzgerald DJ, Pastan I (2008) Differential cellular internalization of anti-CD19 and -CD22 immunotoxins results in different cytotoxic activity. Cancer Res 68:6300-6305.
    • (2008) Cancer Res , vol.68 , pp. 6300-6305
    • Du, X.1    Beers, R.2    Fitzgerald, D.J.3    Pastan, I.4
  • 34
    • 0023156634 scopus 로고
    • Idiotype vaccination against murine B cell lymphoma. Inhibition of tumor immunity by free idiotype protein
    • Kaminski MS, Kitamura K, Maloney DG, Levy R (1987) Idiotype vaccination against murine B cell lymphoma. Inhibition of tumor immunity by free idiotype protein. J Immunol 138:1289-1296. (Pubitemid 17017921)
    • (1987) Journal of Immunology , vol.138 , Issue.4 , pp. 1289-1296
    • Kaminski, M.S.1    Kitamura, K.2    Maloney, D.G.3    Levy, R.4
  • 35
    • 0024236110 scopus 로고
    • Alternative V(kappa) gene rearrangements in a murine B cell lymphoma. An explanation for idiotypic heterogeneity
    • DOI 10.1084/jem.168.5.1607
    • Carroll WL, Starnes CO, Levy R, Levy S (1988) Alternative V kappa gene rearrangements in a murine B cell lymphoma. An explantation for idiotypic heterogeneity. J Exp Med 168:1607-1620. (Pubitemid 19023250)
    • (1988) Journal of Experimental Medicine , vol.168 , Issue.5 , pp. 1607-1620
    • Carroll, W.L.1    Starnes, C.O.2    Levy, R.3    Levy, S.4
  • 36
    • 0028268506 scopus 로고
    • Natural antibody and complement-mediated antigen processing and presentation by B lymphocytes
    • Thornton BP, Větvicka V, Ross GD (1994) Natural antibody and complement-mediated antigen processing and presentation by B lymphocytes. J Immunol 152:1727-1737.
    • (1994) J Immunol , vol.152 , pp. 1727-1737
    • Thornton, B.P.1    Větvicka, V.2    Ross, G.D.3
  • 37
    • 12444297666 scopus 로고    scopus 로고
    • The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
    • DOI 10.1016/j.immuni.2004.11.013, PII S1074761304003759
    • Sixt M, et al. (2005) The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity 22:19-29. (Pubitemid 40143448)
    • (2005) Immunity , vol.22 , Issue.1 , pp. 19-29
    • Sixt, M.1    Kanazawa, N.2    Selg, M.3    Samson, T.4    Roos, G.5    Reinhardt, D.P.6    Pabst, R.7    Lutz, M.B.8    Sorokin, L.9
  • 38
    • 54049088585 scopus 로고    scopus 로고
    • Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes"
    • De Groot AS, et al. (2008) Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes". Blood 112:3303-3311.
    • (2008) Blood , vol.112 , pp. 3303-3311
    • De Groot, A.S.1
  • 39
    • 53449093328 scopus 로고    scopus 로고
    • Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1
    • Ding C, Wang L, Marroquin J, Yan J (2008) Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1. Blood 112:2817-2825.
    • (2008) Blood , vol.112 , pp. 2817-2825
    • Ding, C.1    Wang, L.2    Marroquin, J.3    Yan, J.4
  • 40
    • 40449141768 scopus 로고    scopus 로고
    • Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice
    • DiLillo DJ, et al. (2008) Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice. J Immunol 180:361-371.
    • (2008) J Immunol , vol.180 , pp. 361-371
    • DiLillo, D.J.1
  • 41
    • 70149096297 scopus 로고    scopus 로고
    • Attenuated antibody reaction for the primary antigen but not for the recall antigen of influenza vaccination in patients with non-Hodgkin B-cell lymphoma after the administration of rituximab-CHOP
    • Takata T, et al. (2009) Attenuated antibody reaction for the primary antigen but not for the recall antigen of influenza vaccination in patients with non-Hodgkin B-cell lymphoma after the administration of rituximab-CHOP. J Clin Exp Hematop 49:9-13.
    • (2009) J Clin Exp Hematop , vol.49 , pp. 9-13
    • Takata, T.1
  • 42
    • 70449701405 scopus 로고    scopus 로고
    • Cell-free production of Gaussia princeps luciferase - Antibody fragment bioconjugates for ex vivo detection of tumor cells
    • Patel KG, et al. (2009) Cell-free production of Gaussia princeps luciferase - antibody fragment bioconjugates for ex vivo detection of tumor cells. Biochem Biophys Res Commun 390:971-976.
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 971-976
    • Patel, K.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.