Tualang honey protects keratinocytes from ultraviolet radiation-induced inflammation and DNA damage

Photochemistry and Photobiology

Volumn 88, Issue 5, 2012, Pages 1198-1204

  Ahmad, Israr ^a   Jimenez, Hugo ^a   Yaacob, Nik Soriani ^c   Yusuf, Nabiha ^a,b,c  

^a BIRMINGHAM VA MEDICAL CENTER   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c SCHOOL OF MEDICAL SCIENCES   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

8 OXO 7 HYDRODEOXYGUANOSINE; 8-OXO-7-HYDRODEOXYGUANOSINE; ANTIINFLAMMATORY AGENT; BIOLOGICAL MARKER; DEOXYGUANOSINE; DRUG DERIVATIVE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PYRIMIDINE DIMER;

ANIMAL; CELL LINE; CHEMISTRY; CONFERENCE PAPER; CYTOLOGY; DNA DAMAGE; DNA REPAIR; DRUG EFFECT; GENE EXPRESSION; GENETICS; HONEY; INFLAMMATION; KERATINOCYTE; METABOLISM; MOUSE; PATHOLOGY; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; SKIN TUMOR; ULTRAVIOLET RADIATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL MARKERS; CELL LINE; DEOXYGUANOSINE; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION; HONEY; I-KAPPA B PROTEINS; INFLAMMATION; KERATINOCYTES; MICE; NF-KAPPA B; PYRIMIDINE DIMERS; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

MURINAE;

EID: 84865972530     PISSN: 00318655     EISSN: 17511097     Source Type: Journal    
DOI: 10.1111/j.1751-1097.2012.01100.x     Document Type: Conference Paper

References (35)

1. Kovach, B. T., H. H. Sams, and, T. Stasko, (2005) Systemic strategies for chemoprevention of skin cancers in transplant recipients. Clin. Transplant. 19, 726-734. (Pubitemid 41748724)
2. Fisher, M. S., and, M. L. Kripke, (1982) Suppressor T lymphocytes control the development of primary skin cancers in ultraviolet-irradiated mice. Science 4, 1133-1134. (Pubitemid 12063276)
3. Kripke, M. L., (1974) Antigenicity of murine skin tumors induced by ultraviolet light. J. Natl Cancer Inst. 53, 1333-1336.
4. Berneburg, M., and, J. Krutmann, (2000) Photoimmunology, DNA repair and photocarcinogenesis. J. Photochem. Photobiol. B 54, 87-93. (Pubitemid 30224073)
5. D'Errico, M., T. Lemma, A. Calcagnile, L. Proietti De Santis, and, E. Dogliotti, (2007) Cell type and DNA damage specific response of human skin cells to environmental agents. Mutat. Res. 3, 37-47. (Pubitemid 44909215)
6. Campbell, C., A. G. Quinn, B. Angus, P. M. Farr, and, J. L. Rees, (1993) Wavelength specific patterns of p53 induction in human skin following exposure to UV radiation. Cancer Res. 15, 2697-2699. (Pubitemid 23180497)
7. Latonen, L., and, M. Laiho, (2005) Cellular UV damage responses - Functions of tumor suppressor p53. Biochim. Biophys. Acta 25, 71-89. (Pubitemid 40982559)
8. Devary, Y., C. Rosette, J. A. DiDonato, and, M. Karin, (1993) NF-kappa B activation by ultraviolet light not dependent on a nuclear signal. Science 10, 1442-1445. (Pubitemid 23334264)
9. Rittié, L., and, G. J. Fisher, (2002) UV-light-induced signal cascades and skin aging. Ageing Res. Rev. 1, 705-720. (Pubitemid 38344146)
10. Halliday, G. M., (2005) Inflammation, gene mutation and photoimmunosuppression in response to UVR-induced oxidative damage contributes to photocarcinogenesis. Mutat. Res. 1, 107-120. (Pubitemid 40313436)
11. Nishigori, C., Y. Hattori, and, S. Toyokuni, (2004) Role of reactive oxygen species in skin carcinogenesis. Antioxid. Redox Signal. 6, 561-570. (Pubitemid 38625376)
12. Peus, D., R. A. Vasa, A. Beyerle, A. Meves, C. Krautmacher, and, M. R. Pittelkow, (1999) UVB activates ERK1/2 and p38 signaling pathways via reactive oxygen species in cultured keratinocytes. J. Invest. Dermatol. 112, 751-756. (Pubitemid 29220718)
13. Muthusamy, V., and, T. J. Piva, (2010) The UV response of the skin: A review of the MAPK, NFkappaB and TNFalpha signal transduction pathways. Arch. Dermatol. Res. 302, 5-17.
14. Mori, E., A. Takahashi, K. Kitagawa, S. Kakei, D. Tsujinaka, M. Unno, S. Nishikawa, K. Ohnishi, M. Hatoko, N. Murata, M. Watanabe, Y. Furusawa, and, T. Ohnishi, (2008) Time course and spacial distribution of UV effects on human skin in organ culture. J. Radiat. Res. (Tokyo) 49, 269-277. (Pubitemid 351744279)
15. Ryu, H. C., C. Kim, J. Y. Kim, J. H. Chung, and, J. H. Kim, (2010) UVB radiation induces apoptosis in keratinocytes by activating a pathway linked to "BLT2-reactive oxygen species. J. Invest. Dermatol. 130, 1095-1106.
16. Averbeck, M., S. Beilharz, M. Bauer, C. Gebhardt, A. Hartmann, K. Hochleitner, F. Kauer, U. Voith, J. C. Simon, and, C. Termeer, (2006) In situ profiling and quantification of cytokines released during ultraviolet B-induced inflammation by combining dermal microdialysis and protein microarrays. Exp. Dermatol. 15, 447-454.
17. Quan, T., Z. Qin, W. Xia, Y. Shao, J. J. Voorhees, and, G. J. Fisher, (2009) Matrix-degrading metalloproteinases in photoaging. J. Investig. Dermatol. Symp. Proc. 14, 20-24.
18. Von Thaler, A. K., Y. Kamenisch, and, M. Berneburg, (2010) The role of ultraviolet radiation in melanomagenesis. Exp. Dermatol. 19, 81-88.
19. Aljadi, A. M., and, M. Y. Kamaruddin, (2004) Evaluation of the phenolic contents and antioxidant capacities of two Malaysian floral honeys. Food Chem. 85, 513-518. (Pubitemid 38142496)
20. Gheldof, N., X.-H. Wang, and, N. J. Engeseth, (2002) Identification and quantification of antioxidant components of honeys from various floral sources. J. Agric. Food. Chem. 50, 5870-5877. (Pubitemid 35155307)
21. Ainul Hafiza, A. H., N. Yusof, and, A. Maimon, (2005) Potential of Malaysian local honey as an antibacterial agent. Sains Malays. 34, 17-20.
22. Ghazali, F. C., (2009) Morphological characterization study of Malaysian honey - A VPSEM, EDX randomised attempt. Ann. Microscopy 9, 93-102.
23. Kassim, M., M. Achoui, M. R. Mustafa, M. A. Mohd, and, K. M. Yusoff, (2010) Ellagic acid, phenolic acids, and flavonoids in Malaysian honey extracts demonstrate in vitro anti-inflammatory activity. J. Nutr. Res. 30, 650-659.
24. Mitchell, D. L., B. Volkmer, E. W. Breitbart, M. Byrom, M. G. Lowery, and, R. Greinert, (2001) Identification of a non-dividing subpopulation of mouse and human epidermal cells exhibiting high levels of persistent ultraviolet photodamage. J. Invest. Dermatol. 117, 590-595. (Pubitemid 32955585)
25. Adhami, V. M., F. Afaq, and, N. Ahmad, (2003) Suppression of ultraviolet B exposure-mediated activation of NF-kappaB in normal human keratinocytes by resveratrol. Neoplasia 5, 74-82. (Pubitemid 36151060)
26. Pupe, A., R. Moison, P. De Haes, G. B. van Henegouwen, L. Rhodes, H. Degreef, and, M. Garmyn, (2002) Eicosapentaenoic acid, a n-3 polyunsaturated fatty acid differentially modulates TNF-alpha, IL-1alpha, IL-6 and PGE2 expression in UVB-irradiated human keratinocytes. J. Invest. Dermatol. 118 (4), 692-698. (Pubitemid 34309991)
27. Chang, E. J., J. K. Kundu, L. Liu, J. W. Shin, and, Y. J. Surh, (2011) Ultraviolet B radiation activates NF-κB and induces iNOS expression in HR-1 hairless mouse skin: Role of IκB kinase-β. Mol. Carcinog. 50, 310-317.
28. Van Dross, R. T., X. Hong, S. Essengue, S. M. Fischer, and, J. C. Pelling, (2007) Modulation of UVB-induced and basal cyclooxygenase-2 (COX-2) expression by apigenin in mouse keratinocytes: Role of USF transcription factors. Mol. Carcinog. 46 (4), 303-314. (Pubitemid 46608889)
29. Herschman, H. R., (1994) Regulation of prostaglandin synthase-1 and prostaglandin synthase-2. Cancer Metastasis Rev. 13, 241-256.
30. De Gruijl, F. R., and, H. Rebel, (2008) Early events in UV carcinogenesis - DNA damage, target cells and mutant p53 foci. Photochem. Photobiol. 84, 382-387. (Pubitemid 351421390)
31. Bowden, G. T., (2004) Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling. Nat. Rev. Cancer 4, 23-35. (Pubitemid 38082151)
32. Afaq, F., V. M. Adhami, and, H. Mukhtar, (2005) Photochemoprevention of ultraviolet B signaling and photocarcinogenesis. Mutat. Res. 571, 153-173. (Pubitemid 40313439)
33. Syazana, M. S. N., A. S. Halim, S. H. Gan, and, S. Shamsuddin, (2011) Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. BMC Complement. Altern. Med. 11, 82-89.
34. Chiang, Y. M., C. P. Lo, Y. P. Chen, S. Y. Wang, N. S. Yang, Y. H. Kuo, and, L. F. Shyur, (2005) Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br. J. Pharmacol. 146, 352-363.
35. Karin, M., (2008) The IkappaB kinase - A bridge between inflammation and cancer. Cell Res. 18, 334-342. (Pubitemid 351333897)