Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic

Molecular Pharmaceutics

Volumn 9, Issue 9, 2012, Pages 2669-2676

  Thomas, Thommey P ^a,b   Huang, Baohua ^a,b   Choi, Seok Ki ^a,b   Silpe, Justin E ^c   Kotlyar, Alina ^a,b   Desai, Ankur M ^a,b   Zong, Hong ^a,b   Gam, Jeremy ^a,b   Joice, Melvin ^a,b   Baker, James R ^a,b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

cancer; dendrimer; drug delivery; methotrexate; nanoparticle

Indexed keywords

ANTINEOPLASTIC AGENT; DENDRIMER; DIHYDROFOLATE REDUCTASE; ESTERASE; FOLATE BINDING PROTEIN; FOLATE RECEPTOR; METHOTREXATE;

ARTICLE; CLICK CHEMISTRY; CYTOTOXICITY; DRUG CONJUGATION; DRUG SYNTHESIS; HUMAN; INTERNALIZATION; MOLECULARLY TARGETED THERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURFACE PLASMON RESONANCE;

BIOLOGICAL AVAILABILITY; CELL LINE, TUMOR; DENDRIMERS; ESTERASES; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; HUMANS; KB CELLS; METHOTREXATE; MOLECULAR TARGETED THERAPY; NEOPLASMS; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84865962110     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp3002232     Document Type: Article

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