메뉴 건너뛰기




Volumn 124, Issue 3, 2012, Pages 425-438

NF-κB contributes to the detrimental effects of social isolation after experimental stroke

Author keywords

Isolation; Middle cerebral artery occlusion; Neuroinflammation; NF kappaB; Pair housing

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; PYRROLIDINE DITHIOCARBAMATE;

EID: 84865862712     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-012-0990-8     Document Type: Article
Times cited : (64)

References (57)
  • 1
    • 20444400792 scopus 로고    scopus 로고
    • Social isolation and outcomes post stroke
    • DOI 10.1212/01.WNL.0000163510.79351.AF
    • Boden-Albala B, Litwak E, Elkind MS, Rundek T, Sacco RL (2005) Social isolation and outcomes post stroke. Neurology 64(11):1888-1892 (Pubitemid 40800702)
    • (2005) Neurology , vol.64 , Issue.11 , pp. 1888-1892
    • Boden-Albala, B.1    Litwak, E.2    Elkind, M.S.V.3    Rundek, T.4    Sacco, R.L.5
  • 2
    • 34250325140 scopus 로고    scopus 로고
    • Living alone following first-ever stroke: A prospective study in Turkey identifying the risk factors and evaluating their effects
    • Boru UT, Ozturk E, Tasdemir M, Sur H (2007) Living alone following first-ever stroke: a prospective study in Turkey identifying the risk factors and evaluating their effects. NZ Med J 120(1255):U2559
    • (2007) NZ Med J , vol.120 , Issue.1255
    • Boru, U.T.1    Ozturk, E.2    Tasdemir, M.3    Sur, H.4
  • 3
    • 70349186097 scopus 로고    scopus 로고
    • Alone in the crowd: The structure and spread of loneliness in a large social network
    • Cacioppo JT, Fowler JH, Christakis NA (2009) Alone in the crowd: the structure and spread of loneliness in a large social network. J Pers Soc Psychol 97(6):977-991
    • (2009) J Pers Soc Psychol , vol.97 , Issue.6 , pp. 977-991
    • Cacioppo, J.T.1    Fowler, J.H.2    Christakis, N.A.3
  • 7
    • 69449100713 scopus 로고    scopus 로고
    • Physical activity: One of the easiest ways to protect the brain?
    • Deplanque D, Bordet R (2009) Physical activity: one of the easiest ways to protect the brain? J Neurol Neurosurg Psychiatry 80(9):942
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , Issue.9 , pp. 942
    • Deplanque, D.1    Bordet, R.2
  • 8
    • 33750283385 scopus 로고    scopus 로고
    • Prior TIA, lipid-lowering drug use, and physical activity decrease ischemic stroke severity
    • DOI 10.1212/01.wnl.0000240057.71766.71, PII 0000611420061024000020
    • Deplanque D, Masse I, Lefebvre C, Libersa C, Leys D, Bordet R (2006) Prior TIA, lipid-lowering drug use, and physical activity decrease ischemic stroke severity. Neurology 67(8):1403-1410 (Pubitemid 44632064)
    • (2006) Neurology , vol.67 , Issue.8 , pp. 1403-1410
    • Deplanque, D.1    Masse, I.2    Lefebvre, C.3    Libersa, C.4    Leys, D.5    Bordet, R.6
  • 9
    • 33845217662 scopus 로고    scopus 로고
    • The Relative Strength of C-Reactive Protein and Lipid Levels as Determinants of Ischemic Stroke Compared With Coronary Heart Disease in Women
    • DOI 10.1016/j.jacc.2006.09.030, PII S0735109706025174
    • Everett BM, Kurth T, Buring JE, Ridker PM (2006) The relative strength of C-reactive protein and lipid levels as determinants of ischemic stroke compared with coronary heart disease in women. J Am Coll Cardiol 48(11):2235-2242 (Pubitemid 44855447)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.11 , pp. 2235-2242
    • Everett, B.M.1    Kurth, T.2    Buring, J.E.3    Ridker, P.M.4
  • 11
    • 27344460060 scopus 로고    scopus 로고
    • Alpha-Tocopherol attenuates NFkappaB activation and pro-inflammatory cytokine production in brain and improves recovery from lipopolysaccharide- induced sickness behavior
    • DOI 10.1016/j.jneuroim.2005.08.003, PII S0165572805003322
    • Godbout JP, Berg BM, Krzyszton C, Johnson RW (2005) Alphatocopherol attenuates NFkappaB activation and pro-inflammatory cytokine production in brain and improves recovery from lipopolysaccharide-induced sickness behavior. J Neuroimmunol 169 (1-2):97-105 (Pubitemid 41527095)
    • (2005) Journal of Neuroimmunology , vol.169 , Issue.1-2 , pp. 97-105
    • Godbout, J.P.1    Berg, B.M.2    Krzyszton, C.3    Johnson, R.W.4
  • 12
    • 80053913025 scopus 로고    scopus 로고
    • Association between social isolation and inflammatory markers in depressed and non-depressed individuals: Results from the MONICA/KORA study
    • Hafner S, Emeny RT, Lacruz ME, Baumert J, Herder C, Koenig W, Thorand B, Ladwig KH, Investigators KS (2011) Association between social isolation and inflammatory markers in depressed and non-depressed individuals: results from the MONICA/KORA study. Brain Behav Immun 25(8):1701-1707
    • (2011) Brain Behav Immun , vol.25 , Issue.8 , pp. 1701-1707
    • Hafner, S.1    Emeny, R.T.2    Lacruz, M.E.3    Baumert, J.4    Herder, C.5    Koenig, W.6    Thorand, B.7    Ladwig, K.H.8
  • 13
    • 0037293748 scopus 로고    scopus 로고
    • Loneliness and pathways to disease
    • DOI 10.1016/S0889-1591(02)00073-9, PII S0889159102000739
    • Hawkley LC, Cacioppo JT (2003) Loneliness and pathways to disease. Brain Behav Immun 17(Suppl 1):S98-S105 (Pubitemid 36298520)
    • (2003) Brain, Behavior, and Immunity , vol.17 , Issue.1 SUPPL.
    • Hawkley, L.C.1    Cacioppo, J.T.2
  • 14
    • 33644872215 scopus 로고    scopus 로고
    • Social isolation and the inflammatory response: Sex differences in the enduring effects of a prior stressor
    • Hermes GL, Rosenthal L, Montag A, McClintock MK (2006) Social isolation and the inflammatory response: sex differences in the enduring effects of a prior stressor. Am J Physiol Regul Integr Comp Physiol 290(2):R273-R282
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290 , Issue.2
    • Hermes, G.L.1    Rosenthal, L.2    Montag, A.3    McClintock, M.K.4
  • 15
    • 77955071715 scopus 로고    scopus 로고
    • Social relationships and mortality risk: A meta-analytic review
    • Holt-Lunstad J, Smith TB, Layton JB (2010) Social relationships and mortality risk: a meta-analytic review. PLoS Med 7(7): e1000316
    • (2010) PLoS Med , vol.7 , Issue.7
    • Holt-Lunstad, J.1    Smith, T.B.2    Layton, J.B.3
  • 16
    • 0023808877 scopus 로고
    • Social relationships and health
    • House JS, Landis KR, Umberson D (1988) Social relationships and health. Science 241(4865):540-545
    • (1988) Science , vol.241 , Issue.4865 , pp. 540-545
    • House, J.S.1    Landis, K.R.2    Umberson, D.3
  • 18
    • 71549168952 scopus 로고    scopus 로고
    • Social contact influences histological and behavioral outcomes following cerebral ischemia
    • Karelina K, Norman GJ, Zhang N, DeVries AC (2009) Social contact influences histological and behavioral outcomes following cerebral ischemia. Exp Neurol 220(2):276-282
    • (2009) Exp Neurol , vol.220 , Issue.2 , pp. 276-282
    • Karelina, K.1    Norman, G.J.2    Zhang, N.3    Devries, A.C.4
  • 22
    • 77249129746 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior
    • Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS (2010) Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proc Natl Acad Sci USA 107(6):2669-2674
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.6 , pp. 2669-2674
    • Koo, J.W.1    Russo, S.J.2    Ferguson, D.3    Nestler, E.J.4    Duman, R.S.5
  • 23
    • 19344365429 scopus 로고    scopus 로고
    • Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: Systematic review and meta-analysis
    • DOI 10.1016/S1474-4422(05)70099-5, PII S1474442205700995
    • Kuo HK, Yen CJ, Chang CH, Kuo CK, Chen JH, Sorond F (2005) Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis. Lancet Neurol 4(6):371-380 (Pubitemid 40720034)
    • (2005) Lancet Neurology , vol.4 , Issue.6 , pp. 371-380
    • Kuo, H.-K.1    Yen, C.-J.2    Chang, C.-H.3    Kuo, C.-K.4    Chen, J.-H.5    Sorond, F.6
  • 24
    • 0025910956 scopus 로고
    • Isolation accelerates reproductive senescence and alters its predictors in female rats
    • LeFevre J, McClintock MK (1991) Isolation accelerates reproductive senescence and alters its predictors in female rats. Horm Behav 25(2):258-272
    • (1991) Horm Behav , vol.25 , Issue.2 , pp. 258-272
    • Lefevre, J.1    McClintock, M.K.2
  • 25
    • 33746395171 scopus 로고    scopus 로고
    • Thrombolysis beyond the three-hour time window
    • DOI 10.1080/10641960600549371, PII T688Q5721X517208
    • Leys D, Deplanque D (2006) Thrombolysis beyond the threehour time window. Clin Exp Hypertens 28(3-4):313-316 (Pubitemid 44178505)
    • (2006) Clinical and Experimental Hypertension , vol.28 , Issue.3-4 , pp. 313-316
    • Leys, D.1    Deplanque, D.2
  • 26
    • 78149357102 scopus 로고    scopus 로고
    • Effects of metformin in experimental stroke
    • Li J, Benashski SE, Venna VR, McCullough LD (2010) Effects of metformin in experimental stroke. Stroke 41(11):2645-2652
    • (2010) Stroke , vol.41 , Issue.11 , pp. 2645-2652
    • Li, J.1    Benashski, S.E.2    Venna, V.R.3    McCullough, L.D.4
  • 28
    • 1842664163 scopus 로고    scopus 로고
    • Chronic behavioral testing after focal ischemia in the mouse: Functional recovery and the effects of gender
    • DOI 10.1016/j.expneurol.2004.01.004, PII S0014488604000135
    • Li X, Blizzard KK, Zeng Z, DeVries AC, Hurn PD, McCullough LD (2004) Chronic behavioral testing after focal ischemia in the mouse: functional recovery and the effects of gender. Exp Neurol 187(1):94-104 (Pubitemid 38470016)
    • (2004) Experimental Neurology , vol.187 , Issue.1 , pp. 94-104
    • Li, X.1    Blizzard, K.K.2    Zeng, Z.3    DeVries, A.C.4    Hurn, P.D.5    McCullough, L.D.6
  • 29
    • 65549170958 scopus 로고    scopus 로고
    • Sex differences in caspase activation after stroke
    • Liu F, Li Z, Li J, Siegel C, Yuan R, McCullough LD (2009) Sex differences in caspase activation after stroke. Stroke 40(5):1842-1848
    • (2009) Stroke , vol.40 , Issue.5 , pp. 1842-1848
    • Liu, F.1    Li, Z.2    Li, J.3    Siegel, C.4    Yuan, R.5    McCullough, L.D.6
  • 30
  • 31
    • 61649086903 scopus 로고    scopus 로고
    • TTC, fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion
    • Liu F, Schafer DP, McCullough LD (2009) TTC, fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion. J Neurosci Methods 179(1): 1-8
    • (2009) J Neurosci Methods , vol.179 , Issue.1 , pp. 1-8
    • Liu, F.1    Schafer, D.P.2    McCullough, L.D.3
  • 32
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20:84-91 (Pubitemid 19040218)
    • (1989) Stroke , vol.20 , Issue.1 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 35
    • 33646010041 scopus 로고    scopus 로고
    • Roles for NF-kappaB in nerve cell survival, plasticity, and disease
    • Mattson MP, Meffert MK (2006) Roles for NF-kappaB in nerve cell survival, plasticity, and disease. Cell Death Differ 13(5): 852-860
    • (2006) Cell Death Differ , vol.13 , Issue.5 , pp. 852-860
    • Mattson, M.P.1    Meffert, M.K.2
  • 36
    • 0038268485 scopus 로고    scopus 로고
    • Estrogen and ischemic neuroprotection: An integrated view
    • DOI 10.1016/S1043-2760(03)00076-6
    • McCullough LD, Hurn PD (2003) Estrogen and ischemic neuroprotection: an integrated view. Trends Endocrinol Metab TEM 14(5):228-235 (Pubitemid 36841481)
    • (2003) Trends in Endocrinology and Metabolism , vol.14 , Issue.5 , pp. 228-235
    • McCullough, L.D.1    Hurn, P.D.2
  • 37
    • 48149093475 scopus 로고    scopus 로고
    • A functional genomic fingerprint of chronic stress in humans: Blunted glucocorticoid and increased NF-kappaB signaling
    • Miller GE, Chen E, Sze J, Marin T, Arevalo JM, Doll R, Ma R, Cole SW (2008) A functional genomic fingerprint of chronic stress in humans: blunted glucocorticoid and increased NF-kappaB signaling. Biol Psychiatry 64(4):266-272
    • (2008) Biol Psychiatry , vol.64 , Issue.4 , pp. 266-272
    • Miller, G.E.1    Chen, E.2    Sze, J.3    Marin, T.4    Arevalo, J.M.5    Doll, R.6    Ma, R.7    Cole, S.W.8
  • 39
    • 47649096803 scopus 로고    scopus 로고
    • Strong neuroprotection by inhibition of NFkappaB after neonatal hypoxia-ischemia involves apoptotic mechanisms but is independent of cytokines
    • Nijboer CH, Heijnen CJ, Groenendaal F, May MJ, van Bel F, Kavelaars A (2008) Strong neuroprotection by inhibition of NFkappaB after neonatal hypoxia-ischemia involves apoptotic mechanisms but is independent of cytokines. Stroke 39(7):2129-2137
    • (2008) Stroke , vol.39 , Issue.7 , pp. 2129-2137
    • Nijboer, C.H.1    Heijnen, C.J.2    Groenendaal, F.3    May, M.J.4    Van Bel, F.5    Kavelaars, A.6
  • 40
    • 33646164881 scopus 로고    scopus 로고
    • Antioxidant pyrrolidine dithiocarbamate activates Akt-GSK signaling and is neuroprotective in neonatal hypoxia-ischemia
    • Nurmi A, Goldsteins G, Närväinen J, Pihlaja R, Ahtoniemi T, Gröhn O, Koistinaho J (2006) Antioxidant pyrrolidine dithiocarbamate activates Akt-GSK signaling and is neuroprotective in neonatal hypoxia-ischemia. Free Radic Biol Med 40(10):1776-1784
    • (2006) Free Radic Biol Med , vol.40 , Issue.10 , pp. 1776-1784
    • Nurmi, A.1    Goldsteins, G.2    Närväinen, J.3    Pihlaja, R.4    Ahtoniemi, T.5    Gröhn, O.6    Koistinaho, J.7
  • 42
    • 7244259205 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate inhibits translocation of nuclear factor kappa-B in neurons and protects against brain ischaemia with a wide therapeutic time window
    • DOI 10.1111/j.1471-4159.2004.02756.x
    • Nurmi A, Vartiainen N, Pihlaja R, Goldsteins G, Yrjanheikki J, Koistinaho J (2004) Pyrrolidine dithiocarbamate inhibits translocation of nuclear factor kappa-B in neurons and protects against brain ischaemia with a wide therapeutic time window. J Neurochem 91(3):755-765 (Pubitemid 39431168)
    • (2004) Journal of Neurochemistry , vol.91 , Issue.3 , pp. 755-765
    • Nurmi, A.1    Vartiainen, N.2    Pihlaja, R.3    Goldsteins, G.4    Yrjanheikki, J.5    Koistinaho, J.6
  • 43
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl HL (1999) Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18(49):6853-6866
    • (1999) Oncogene , vol.18 , Issue.49 , pp. 6853-6866
    • Pahl, H.L.1
  • 46
    • 0030834399 scopus 로고    scopus 로고
    • Hypercortisolism associated with social subordinance or social isolation among wild baboons
    • Sapolsky RM, Alberts SC, Altmann J (1997) Hypercortisolism associated with social subordinance or social isolation among wild baboons. Arch Gen Psychiatry 54(12):1137-1143 (Pubitemid 27524379)
    • (1997) Archives of General Psychiatry , vol.54 , Issue.12 , pp. 1137-1143
    • Sapolsky, R.M.1    Alberts, S.C.2    Altmann, J.3
  • 49
    • 33751011580 scopus 로고    scopus 로고
    • Social isolation stress and neuroactive steroids
    • DOI 10.1016/j.euroneuro.2006.03.004, PII S0924977X06000514
    • Serra M, Sanna E, Mostallino MC, Biggio G (2007) Social isolation stress and neuroactive steroids. Eur Neuropsychopharmacol 17(1):1-11 (Pubitemid 44751406)
    • (2007) European Neuropsychopharmacology , vol.17 , Issue.1 , pp. 1-11
    • Serra, M.1    Sanna, E.2    Mostallino, M.C.3    Biggio, G.4
  • 50
    • 0028804551 scopus 로고
    • Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses
    • Sha WC, Liou HC, Tuomanen EI, Baltimore D (1995) Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses. Cell 80(2):321-330
    • (1995) Cell , vol.80 , Issue.2 , pp. 321-330
    • Sha, W.C.1    Liou, H.C.2    Tuomanen, E.I.3    Baltimore, D.4
  • 52
    • 33750208494 scopus 로고    scopus 로고
    • Interleukin-1-induced NF-kappaB recruitment to the oxytocin receptor gene inhibits RNA polymerase II - Promoter interactions in cultured human myometrial cells
    • DOI 10.1093/molehr/gal067
    • Soloff MS, Izban MG, Cook DL Jr, Jeng YJ, Mifflin RC (2006) Interleukin-1-induced NF-kappaB recruitment to the oxytocin receptor gene inhibits RNA polymerase II-promoter interactions in cultured human myometrial cells. Mol Hum Reprod 12(10): 619-624 (Pubitemid 44605608)
    • (2006) Molecular Human Reproduction , vol.12 , Issue.10 , pp. 619-624
    • Soloff, M.S.1    Izban, M.G.2    Cook, D.L.3    Jeng, Y.-J.4    Mifflin, R.C.5
  • 53
    • 84856145980 scopus 로고    scopus 로고
    • Stress and social isolation increase vulnerability to stroke
    • Stuller KA, Jarrett B, Devries AC (2011) Stress and social isolation increase vulnerability to stroke. Exp Neurol 233(1):33-39
    • (2011) Exp Neurol , vol.233 , Issue.1 , pp. 33-39
    • Stuller, K.A.1    Jarrett, B.2    Devries, A.C.3
  • 55
    • 5644249564 scopus 로고    scopus 로고
    • Infarct volume quantification in mouse focal cerebral ischemia: A comparison of triphenyltetrazolium chloride and cresyl violet staining techniques
    • DOI 10.1016/j.jneumeth.2004.04.029, PII S0165027004001748
    • Türeyen K, Vemuganti R, Sailor KA, Dempsey RJ (2004) Infarct volume quantification in mouse focal cerebral ischemia: a comparison of triphenyltetrazolium chloride and cresyl violet staining techniques. J Neurosci Methods 139(2):203-207 (Pubitemid 39370846)
    • (2004) Journal of Neuroscience Methods , vol.139 , Issue.2 , pp. 203-207
    • Tureyen, K.1    Vemuganti, R.2    Sailor, K.A.3    Dempsey, R.J.4
  • 56
    • 84855559622 scopus 로고    scopus 로고
    • Preconditioning induces sustained neuroprotection by downregulation of adenosine 50-monophosphate-activated protein kinase
    • Venna VR, Li J, Benashski SE, Tarabishy S, McCullough LD (2012) Preconditioning induces sustained neuroprotection by downregulation of adenosine 50-monophosphate-activated protein kinase. Neuroscience 10(201):280-287
    • (2012) Neuroscience , vol.10 , Issue.201 , pp. 280-287
    • Venna, V.R.1    Li, J.2    Benashski, S.E.3    Tarabishy, S.4    McCullough, L.D.5
  • 57
    • 84856227309 scopus 로고    scopus 로고
    • "Won't You Be my Neighbor?": Deciphering the mechanisms of neuroprotection induced by social interaction
    • Venna VR, McCullough LD (2011) "Won't You Be my Neighbor?": deciphering the mechanisms of neuroprotection induced by social interaction. Stroke 42(12):3329-3330
    • (2011) Stroke , vol.42 , Issue.12 , pp. 3329-3330
    • Venna, V.R.1    McCullough, L.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.