-
1
-
-
80053900941
-
Frequent pathway mutations of splicing machinery in myelodysplasia
-
Yoshida K, Sanada M, Shiraishi Y, Nowak D, Nagata Y, Yamamoto R et al. Frequent pathway mutations of splicing machinery in myelodysplasia. Nature 2011; 478: 64-69.
-
(2011)
Nature
, vol.478
, pp. 64-69
-
-
Yoshida, K.1
Sanada, M.2
Shiraishi, Y.3
Nowak, D.4
Nagata, Y.5
Yamamoto, R.6
-
2
-
-
84555192302
-
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
-
Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet 2011; 44: 53-57.
-
(2011)
Nat Genet
, vol.44
, pp. 53-57
-
-
Graubert, T.A.1
Shen, D.2
Ding, L.3
Okeyo-Owuor, T.4
Lunn, C.L.5
Shao, J.6
-
3
-
-
80054010617
-
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts
-
Papaemmanuil E, Cazzola M, Boultwood J, Malcovati L, Vyas P, Bowen D et al. Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts. N Engl J Med 2011; 365: 1384-1395.
-
(2011)
N Engl J Med
, vol.365
, pp. 1384-1395
-
-
Papaemmanuil, E.1
Cazzola, M.2
Boultwood, J.3
Malcovati, L.4
Vyas, P.5
Bowen, D.6
-
4
-
-
84855370035
-
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
-
Wang L, Lawrence MS, Wan Y, Stojanov P, Sougnez C, Stevenson K et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med 2011; 365: 2497-2506.
-
(2011)
N Engl J Med
, vol.365
, pp. 2497-2506
-
-
Wang, L.1
Lawrence, M.S.2
Wan, Y.3
Stojanov, P.4
Sougnez, C.5
Stevenson, K.6
-
5
-
-
79960036578
-
Wholegenome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
-
Puente XS, Pinyol M, Quesada V, Conde L, Ordonez GR, Villamor N et al. Wholegenome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature 2011; 475: 101-105.
-
(2011)
Nature
, vol.475
, pp. 101-105
-
-
Puente, X.S.1
Pinyol, M.2
Quesada, V.3
Conde, L.4
Ordonez, G.R.5
Villamor, N.6
-
6
-
-
84555171449
-
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
-
Quesada V, Conde L, Villamor N, Ordonez GR, Jares P, Bassaganyas L et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet 2011; 44: 47-52.
-
(2011)
Nat Genet
, vol.44
, pp. 47-52
-
-
Quesada, V.1
Conde, L.2
Villamor, N.3
Ordonez, G.R.4
Jares, P.5
Bassaganyas, L.6
-
7
-
-
79960353160
-
Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation
-
Fabbri G, Rasi S, Rossi D, Trifonov V, Khiabanian H, Ma J et al. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation. J Exp Med 2011; 208: 1389-1401.
-
(2011)
J Exp Med
, vol.208
, pp. 1389-1401
-
-
Fabbri, G.1
Rasi, S.2
Rossi, D.3
Trifonov, V.4
Khiabanian, H.5
Ma, J.6
-
8
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
Wahl MC, Will CL, Luhrmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 2009; 136: 701-718.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Luhrmann, R.3
-
9
-
-
0032570707
-
The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS
-
DOI 10.1074/jbc.273.9.4838
-
Hallier M, Lerga A, Barnache S, Tavitian A, Moreau-Gachelin F. The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS. J Biol Chem 1998; 273: 4838-4842. (Pubitemid 28108632)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.9
, pp. 4838-4842
-
-
Hallier, M.1
Lerga, A.2
Barnache, S.3
Tavitian, A.4
Moreau-Gachelin, F.5
-
10
-
-
27744492954
-
Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export
-
DOI 10.1074/jbc.M501725200
-
Hiriart E, Gruffat H, Buisson M, Mikaelian I, Keppler S, Meresse P et al. Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export. J Biol Chem 2005; 280: 36935-36945. (Pubitemid 41587776)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.44
, pp. 36935-36945
-
-
Hiriart, E.1
Gruffat, H.2
Buisson, M.3
Mikaelian, I.4
Keppler, S.5
Meresse, P.6
Mercher, T.7
Bernard, O.A.8
Sergeant, A.9
Manet, E.10
-
11
-
-
14344280044
-
Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia
-
DOI 10.1073/pnas.101001498
-
Mercher T, Coniat MB, Monni R, Mauchauffe M, Nguyen Khac F, Gressin L et al. Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia. Proc Natl Acad Sci USA 2001; 98: 5776-5779. (Pubitemid 32435718)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.10
, pp. 5776-5779
-
-
Mercher, T.1
Coniat, M.B.-L.2
Monni, R.3
Mauchauffe, M.4
Khac, F.N.5
Gressin, L.6
Mugneret, F.7
Leblanc, T.8
Dastugue, N.9
Berger, R.10
Bernard, O.A.11
-
12
-
-
33845984008
-
RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway
-
DOI 10.1074/jbc.M608745200
-
Lindtner S, Zolotukhin AS, Uranishi H, Bear J, Kulkarni V, Smulevitch S et al. RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway. J Biol Chem 2006; 281: 36915-36928. (Pubitemid 46042160)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.48
, pp. 36915-36928
-
-
Lindtner, S.1
Zolotukhin, A.S.2
Uranishi, H.3
Bear, J.4
Kulkarni, V.5
Smulevitch, S.6
Samiotaki, M.7
Panayotou, G.8
Felber, B.K.9
Pavlakis, G.N.10
-
13
-
-
0034941166
-
Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia
-
DOI 10.1038/90054
-
Ma Z, Morris SW, Valentine V, Li M, Herbrick JA, Cui X et al. Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet 2001; 28: 220-221. (Pubitemid 32626023)
-
(2001)
Nature Genetics
, vol.28
, Issue.3
, pp. 220-221
-
-
Ma, Z.1
Morris, S.W.2
Valentine, V.3
Li, M.4
Herbrick, J.A.5
Cui, X.6
Bouman, D.7
Li, Y.8
Mehta, P.K.9
Nizetic, D.10
Kaneko, Y.11
Chan, G.C.F.12
Chan, L.C.13
Squire, J.14
Scherer, S.W.15
Hitzler, J.K.16
-
14
-
-
67649435612
-
Nuclear pore proteins and cancer
-
Xu S, Powers MA. Nuclear pore proteins and cancer. Semin Cell Dev Biol 2009; 20: 620-630.
-
(2009)
Semin Cell Dev Biol
, vol.20
, pp. 620-630
-
-
Xu, S.1
Powers, M.A.2
-
15
-
-
83455220210
-
NUP98 gene fusions and hematopoietic malignancies: Common themes and new biologic insights
-
Gough SM, Slape CI, Aplan PD. NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights. Blood 2011; 118: 6247-6257.
-
(2011)
Blood
, vol.118
, pp. 6247-6257
-
-
Gough, S.M.1
Slape, C.I.2
Aplan, P.D.3
-
16
-
-
77953800169
-
Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1
-
Ren Y, Seo HS, Blobel G, Hoelz A. Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1. Proc Natl Acad Sci USA 2010; 107: 10406-10411.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 10406-10411
-
-
Ren, Y.1
Seo, H.S.2
Blobel, G.3
Hoelz, A.4
-
17
-
-
33748657386
-
Nup214 is required for CRM1-dependent nuclear protein export in vivo
-
DOI 10.1128/MCB.00342-06
-
Hutten S, Kehlenbach RH. Nup214 is required for CRM1-dependent nuclear protein export in vivo. Mol Cell Biol 2006; 26: 6772-6785. (Pubitemid 44387628)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.18
, pp. 6772-6785
-
-
Hutten, S.1
Kehlenbach, R.H.2
-
18
-
-
14644431836
-
Mammalian Polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1
-
DOI 10.1101/gad.1284605
-
Isono K, Mizutani-Koseki Y, Komori T, Schmidt-Zachmann MS, Koseki H. Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1. Genes Dev 2005; 19: 536-541. (Pubitemid 40314986)
-
(2005)
Genes and Development
, vol.19
, Issue.5
, pp. 536-541
-
-
Isono, K.1
Mizutani-Koseki, Y.2
Komori, T.3
Schmidt-Zachmann, M.S.4
Koseki, H.5
-
19
-
-
80051589767
-
Selfrenewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia
-
Kikushige Y, Ishikawa F, Miyamoto T, Shima T, Urata S, Yoshimoto G et al. Selfrenewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia. Cancer Cell 2011; 20: 246-259.
-
(2011)
Cancer Cell
, vol.20
, pp. 246-259
-
-
Kikushige, Y.1
Ishikawa, F.2
Miyamoto, T.3
Shima, T.4
Urata, S.5
Yoshimoto, G.6
-
20
-
-
79960062301
-
TET2 Inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron C, Couronne L, Della Valle V, Lopez CK, Plo I, Wagner-Ballon O et al. TET2 Inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 2011; 20: 25-38.
-
(2011)
Cancer Cell
, vol.20
, pp. 25-38
-
-
Quivoron, C.1
Couronne, L.2
Della Valle, V.3
Lopez, C.K.4
Plo, I.5
Wagner-Ballon, O.6
-
21
-
-
84855718050
-
TET2 and DNMT3A mutations in human t-cell lymphoma
-
Couronne L, Bastard C, Bernard OA. TET2 and DNMT3A Mutations in Human T-Cell Lymphoma. N Engl J Med 2012; 366: 95-96.
-
(2012)
N Engl J Med
, vol.366
, pp. 95-96
-
-
Couronne, L.1
Bastard, C.2
Bernard, O.A.3
-
22
-
-
84860767817
-
SF3B1 mutations in myelodysplastic syndromes: Clinical associations and prognostic implications
-
e-pub ahead of print 8 November 2011
-
Damm F, Thol F, Kosmider O, Kade S, Loffeld P, Dreyfus F et al. SF3B1 mutations in myelodysplastic syndromes: clinical associations and prognostic implications. Leukemia 2011; e-pub ahead of print 8 November 2011.
-
(2011)
Leukemia
-
-
Damm, F.1
Thol, F.2
Kosmider, O.3
Kade, S.4
Loffeld, P.5
Dreyfus, F.6
-
23
-
-
84855841586
-
SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value
-
Patnaik MM, Lasho TL, Hodnefield JM, Knudson RA, Ketterling RP, Garcia-Manero G et al. SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value. Blood 2011; 119: 569-572.
-
(2011)
Blood
, vol.119
, pp. 569-572
-
-
Patnaik, M.M.1
Lasho, T.L.2
Hodnefield, J.M.3
Knudson, R.A.4
Ketterling, R.P.5
Garcia-Manero, G.6
-
24
-
-
84857994411
-
SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts
-
Visconte V, Makishima H, Jankowska A, Szpurka H, Traina F, Jerez A et al. SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts. Leukemia 2011; 26: 542-545.
-
(2011)
Leukemia
, vol.26
, pp. 542-545
-
-
Visconte, V.1
Makishima, H.2
Jankowska, A.3
Szpurka, H.4
Traina, F.5
Jerez, A.6
-
25
-
-
83455234787
-
Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
-
Malcovati L, Papaemmanuil E, Bowen DT, Boultwood J, Della Porta MG, Pascutto C et al. Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms. Blood 2011; 118: 6239-6246.
-
(2011)
Blood
, vol.118
, pp. 6239-6246
-
-
Malcovati, L.1
Papaemmanuil, E.2
Bowen, D.T.3
Boultwood, J.4
Della Porta, M.G.5
Pascutto, C.6
-
26
-
-
84255160977
-
Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: Association with progression and fludarabine-refractoriness
-
Rossi D, Bruscaggin A, Spina V, Rasi S, Khiabanian H, Messina M et al. Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness. Blood 2011; 118: 6904-6908.
-
(2011)
Blood
, vol.118
, pp. 6904-6908
-
-
Rossi, D.1
Bruscaggin, A.2
Spina, V.3
Rasi, S.4
Khiabanian, H.5
Messina, M.6
-
27
-
-
84859597590
-
Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
-
Makishima H, Visconte V, Sakaguchi H, Jankowska AM, Abu Kar S, Jerez A et al. Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis. Blood 2012; 119: 3203-3210.
-
(2012)
Blood
, vol.119
, pp. 3203-3210
-
-
Makishima, H.1
Visconte, V.2
Sakaguchi, H.3
Jankowska, A.M.4
Abu Kar, S.5
Jerez, A.6
-
28
-
-
84859856420
-
Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes
-
Thol F, Kade S, Schlarmann C, Loffeld P, Morgan M, Krauter J et al. Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes. Blood 2012; 119: 3578-3584.
-
(2012)
Blood
, vol.119
, pp. 3578-3584
-
-
Thol, F.1
Kade, S.2
Schlarmann, C.3
Loffeld, P.4
Morgan, M.5
Krauter, J.6
-
29
-
-
84859595800
-
Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes
-
Damm F, Kosmider O, Gelsi-Boyer V, Renneville A, Carbuccia N, Hidalgo-Curtis C et al. Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes. Blood 2012; 119: 3211-3218.
-
(2012)
Blood
, vol.119
, pp. 3211-3218
-
-
Damm, F.1
Kosmider, O.2
Gelsi-Boyer, V.3
Renneville, A.4
Carbuccia, N.5
Hidalgo-Curtis, C.6
-
30
-
-
84861082246
-
Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms reveals recurrent SRSF2 mutations which are associated with adverse outcome
-
e-pub ahead of print 19 March 2012
-
Zhang SJ, Rampal R, Manshouri T, Patel J, Mensah N, Kayserian A et al. Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms reveals recurrent SRSF2 mutations which are associated with adverse outcome. Blood 2012; e-pub ahead of print 19 March 2012.
-
(2012)
Blood
-
-
Zhang, S.J.1
Rampal, R.2
Manshouri, T.3
Patel, J.4
Mensah, N.5
Kayserian, A.6
-
32
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
DOI 10.1038/nature06734, PII NATURE06734
-
Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 2008; 452: 230-233. (Pubitemid 351380249)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
33
-
-
80052223272
-
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming
-
Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK et al. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell 2011; 147: 132-146.
-
(2011)
Cell
, vol.147
, pp. 132-146
-
-
Gabut, M.1
Samavarchi-Tehrani, P.2
Wang, X.3
Slobodeniuc, V.4
O'Hanlon, D.5
Sung, H.K.6
-
36
-
-
79957543093
-
More than a splicing code: Integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation
-
Luco RF, Misteli T. More than a splicing code: integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation. Curr Opin Genet Dev 2011; 21: 366-372.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 366-372
-
-
Luco, R.F.1
Misteli, T.2
-
37
-
-
77149175671
-
Regulation of alternative splicing by histone modifications
-
Luco RF, Pan Q, Tominaga K, Blencowe BJ, Pereira-Smith OM, Misteli T. Regulation of alternative splicing by histone modifications. Science 2010; 327: 996-1000.
-
(2010)
Science
, vol.327
, pp. 996-1000
-
-
Luco, R.F.1
Pan, Q.2
Tominaga, K.3
Blencowe, B.J.4
Pereira-Smith, O.M.5
Misteli, T.6
-
38
-
-
0034812915
-
Human STAGa complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo
-
DOI 10.1128/MCB.21.20.6782-6795.2001
-
Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK et al. Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo. Mol Cell Biol 2001; 21: 6782-6795. (Pubitemid 32911240)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.20
, pp. 6782-6795
-
-
Martinez, E.1
Palhan, V.B.2
Tjernberg, A.3
Lymar, E.S.4
Gamper, A.M.5
Kundu, T.K.6
Chait, B.T.7
Roeder, R.G.8
-
39
-
-
80053597137
-
A Pre-mRNA degradation pathway that selectively targets intron-containing genes requires the nuclear poly(A)-binding protein
-
Lemieux C, Marguerat S, Lafontaine J, Barbezier N, Bahler J, Bachand F. A Pre-mRNA degradation pathway that selectively targets intron-containing genes requires the nuclear poly(A)-binding protein. Mol Cell 2011; 44: 108-119.
-
(2011)
Mol Cell
, vol.44
, pp. 108-119
-
-
Lemieux, C.1
Marguerat, S.2
Lafontaine, J.3
Barbezier, N.4
Bahler, J.5
Bachand, F.6
-
40
-
-
0028061671
-
Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit
-
Jenny A, Hauri HP, Keller W. Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit. Mol Cell Biol 1994; 14: 8183-8190. (Pubitemid 24373567)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.12
, pp. 8183-8190
-
-
Jenny, A.1
Hauri, H.-P.2
Keller, W.3
-
41
-
-
79954598438
-
A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export
-
Montpetit B, Thomsen ND, Helmke KJ, Seeliger MA, Berger JM, Weis K. A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export. Nature 2011; 472: 238-242.
-
(2011)
Nature
, vol.472
, pp. 238-242
-
-
Montpetit, B.1
Thomsen, N.D.2
Helmke, K.J.3
Seeliger, M.A.4
Berger, J.M.5
Weis, K.6
-
42
-
-
35449007714
-
The DDX3 subfamily of the DEAD box helicases: Divergent roles as unveiled by studying different organisms and in vitro assays
-
DOI 10.2174/092986707782023677
-
Rosner A, Rinkevich B. The DDX3 subfamily of the DEAD box helicases: divergent roles as unveiled by studying different organisms and in vitro assays. Curr Med Chem 2007; 14: 2517-2525. (Pubitemid 47618039)
-
(2007)
Current Medicinal Chemistry
, vol.14
, Issue.23
, pp. 2517-2525
-
-
Rosner, A.1
Rinkevich, B.2
-
43
-
-
33947726050
-
CRM1-mediated nuclear export: to the pore and beyond
-
DOI 10.1016/j.tcb.2007.02.003, PII S096289240700030X
-
Hutten S, Kehlenbach RH. CRM1-mediated nuclear export: to the pore and beyond. Trends Cell Biol 2007; 17: 193-201. (Pubitemid 46507806)
-
(2007)
Trends in Cell Biology
, vol.17
, Issue.4
, pp. 193-201
-
-
Hutten, S.1
Kehlenbach, R.H.2
-
44
-
-
79951494668
-
Initial genome sequencing and analysis of multiple myeloma
-
Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC et al. Initial genome sequencing and analysis of multiple myeloma. Nature 2011; 471: 467-472.
-
(2011)
Nature
, vol.471
, pp. 467-472
-
-
Chapman, M.A.1
Lawrence, M.S.2
Keats, J.J.3
Cibulskis, K.4
Sougnez, C.5
Schinzel, A.C.6
-
45
-
-
58149236691
-
The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities
-
Schaeffer D, Tsanova B, Barbas A, Reis FP, Dastidar EG, Sanchez-Rotunno M et al. The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities. Nat Struct Mol Biol 2009; 16: 56-62.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 56-62
-
-
Schaeffer, D.1
Tsanova, B.2
Barbas, A.3
Reis, F.P.4
Dastidar, E.G.5
Sanchez-Rotunno, M.6
-
46
-
-
79960065233
-
XUTs are a class of Xrn1-sensitive antisense regulatory non-coding RNA in yeast
-
van Dijk EL, Chen CL, d'Aubenton-Carafa Y, Gourvennec S, Kwapisz M, Roche V et al. XUTs are a class of Xrn1-sensitive antisense regulatory non-coding RNA in yeast. Nature 2011; 475: 114-117.
-
(2011)
Nature
, vol.475
, pp. 114-117
-
-
Van Dijk, E.L.1
Chen, C.L.2
D'Aubenton-Carafa, Y.3
Gourvennec, S.4
Kwapisz, M.5
Roche, V.6
-
47
-
-
84862776906
-
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
-
Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 2012; 481: 506-510.
-
(2012)
Nature
, vol.481
, pp. 506-510
-
-
Ding, L.1
Ley, T.J.2
Larson, D.E.3
Miller, C.A.4
Koboldt, D.C.5
Welch, J.S.6
-
48
-
-
81555205691
-
Leucine-rich repeat kinase 2 (LRRK2) cellular biology: A review of recent advances in identifying physiological substrates and cellular functions
-
Drolet RE, Sanders JM, Kern JT. Leucine-rich repeat kinase 2 (LRRK2) cellular biology: a review of recent advances in identifying physiological substrates and cellular functions. J Neurogenet 2011; 25: 140-151.
-
(2011)
J Neurogenet
, vol.25
, pp. 140-151
-
-
Drolet, R.E.1
Sanders, J.M.2
Kern, J.T.3
-
49
-
-
80053198659
-
Molecular dissection of the 5q deletion in myelodysplastic syndrome
-
Ebert BL. Molecular dissection of the 5q deletion in myelodysplastic syndrome. Semin Oncol 2011; 38: 621-626.
-
(2011)
Semin Oncol
, vol.38
, pp. 621-626
-
-
Ebert, B.L.1
-
50
-
-
82755192848
-
Biological validation that SF3b is a target of the antitumor macrolide pladienolide
-
Yokoi A, Kotake Y, Takahashi K, Kadowaki T, Matsumoto Y, Minoshima Y et al. Biological validation that SF3b is a target of the antitumor macrolide pladienolide. FEBS J 2011; 278: 4870-4880.
-
(2011)
FEBS J
, vol.278
, pp. 4870-4880
-
-
Yokoi, A.1
Kotake, Y.2
Takahashi, K.3
Kadowaki, T.4
Matsumoto, Y.5
Minoshima, Y.6
-
51
-
-
80052269038
-
Analysis of the coding genome of diffuse large B-cell lymphoma
-
Pasqualucci L, Trifonov V, Fabbri G, Ma J, Rossi D, Chiarenza A et al. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet 2011; 43: 830-837.
-
(2011)
Nat Genet
, vol.43
, pp. 830-837
-
-
Pasqualucci, L.1
Trifonov, V.2
Fabbri, G.3
Ma, J.4
Rossi, D.5
Chiarenza, A.6
-
52
-
-
80052029516
-
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
-
Morin RD, Mendez-Lago M, Mungall AJ, Goya R, Mungall KL, Corbett RD et al. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature 2011; 476: 298-303.
-
(2011)
Nature
, vol.476
, pp. 298-303
-
-
Morin, R.D.1
Mendez-Lago, M.2
Mungall, A.J.3
Goya, R.4
Mungall, K.L.5
Corbett, R.D.6
-
53
-
-
75749124332
-
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
-
Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet 2010; 42: 181-185.
-
(2010)
Nat Genet
, vol.42
, pp. 181-185
-
-
Morin, R.D.1
Johnson, N.A.2
Severson, T.M.3
Mungall, A.J.4
An, J.5
Goya, R.6
-
54
-
-
78650454078
-
Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
-
Sneeringer CJ, Scott MP, Kuntz KW, Knutson SK, Pollock RM, Richon VM et al. Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas. Proc Natl Acad Sci USA 2010; 107: 20980-20985.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20980-20985
-
-
Sneeringer, C.J.1
Scott, M.P.2
Kuntz, K.W.3
Knutson, S.K.4
Pollock, R.M.5
Richon, V.M.6
-
55
-
-
79952167230
-
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
-
Yap DB, Chu J, Berg T, Schapira M, Cheng SW, Moradian A et al. Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Blood 2011; 117: 2451-2459.
-
(2011)
Blood
, vol.117
, pp. 2451-2459
-
-
Yap, D.B.1
Chu, J.2
Berg, T.3
Schapira, M.4
Cheng, S.W.5
Moradian, A.6
-
56
-
-
79952430906
-
Inactivating mutations of acetyltransferase genes in B-cell lymphoma
-
Pasqualucci L, Dominguez-Sola D, Chiarenza A, Fabbri G, Grunn A, Trifonov V et al. Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature 2011; 471: 189-195.
-
(2011)
Nature
, vol.471
, pp. 189-195
-
-
Pasqualucci, L.1
Dominguez-Sola, D.2
Chiarenza, A.3
Fabbri, G.4
Grunn, A.5
Trifonov, V.6
-
57
-
-
77953973940
-
Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
-
Pasini D, Malatesta M, Jung HR, Walfridsson J, Willer A, Olsson L et al. Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes. Nucleic Acids Res 2010; 38: 4958-4969.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 4958-4969
-
-
Pasini, D.1
Malatesta, M.2
Jung, H.R.3
Walfridsson, J.4
Willer, A.5
Olsson, L.6
-
58
-
-
78650012116
-
Cooperative epigenetic modulation by cancer amplicon genes
-
Rui L, Emre NC, Kruhlak MJ, Chung HJ, Steidl C, Slack G et al. Cooperative epigenetic modulation by cancer amplicon genes. Cancer Cell 2010; 18: 590-605.
-
(2010)
Cancer Cell
, vol.18
, pp. 590-605
-
-
Rui, L.1
Emre, N.C.2
Kruhlak, M.J.3
Chung, H.J.4
Steidl, C.5
Slack, G.6
-
61
-
-
77449089365
-
A new genetic lesion in B-CLL: A NOTCH1 PEST domain mutation
-
Di Ianni M, Baldoni S, Rosati E, Ciurnelli R, Cavalli L, Martelli MF et al. A new genetic lesion in B-CLL: a NOTCH1 PEST domain mutation. Br J Haematol 2009; 146: 689-691.
-
(2009)
Br J Haematol
, vol.146
, pp. 689-691
-
-
Di Ianni, M.1
Baldoni, S.2
Rosati, E.3
Ciurnelli, R.4
Cavalli, L.5
Martelli, M.F.6
-
62
-
-
84857763426
-
Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma
-
Kridel R, Meissner B, Rogic S, Boyle M, Telenius A, Woolcock B et al. Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma. Blood 2012; 119: 1963-1971.
-
(2012)
Blood
, vol.119
, pp. 1963-1971
-
-
Kridel, R.1
Meissner, B.2
Rogic, S.3
Boyle, M.4
Telenius, A.5
Woolcock, B.6
-
63
-
-
80555129351
-
Oncogenic and tumor suppressor functions of Notch in cancer: It's NOTCH what you think
-
Lobry C, Oh P, Aifantis I. Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think. J Exp Med 2011; 208: 1931-1935.
-
(2011)
J Exp Med
, vol.208
, pp. 1931-1935
-
-
Lobry, C.1
Oh, P.2
Aifantis, I.3
-
64
-
-
45149123052
-
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
-
DOI 10.1084/jem.20080277
-
Thompson BJ, Jankovic V, Gao J, Buonamici S, Vest A, Lee JM et al. Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7. J Exp Med 2008; 205: 1395-1408. (Pubitemid 351831495)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.6
, pp. 1395-1408
-
-
Thompson, B.J.1
Jankovic, V.2
Gao, J.3
Buonamici, S.4
Vest, A.5
Lee, J.M.6
Zavadil, J.7
Nimer, S.D.8
Aifantis, I.9
-
65
-
-
84855854025
-
Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
-
Rossi D, Rasi S, Fabbri G, Spina V, Fangazio M, Forconi F et al. Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia. Blood 2012; 119: 521-529.
-
(2012)
Blood
, vol.119
, pp. 521-529
-
-
Rossi, D.1
Rasi, S.2
Fabbri, G.3
Spina, V.4
Fangazio, M.5
Forconi, F.6
-
66
-
-
77958567414
-
NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL
-
Sportoletti P, Baldoni S, Cavalli L, Del Papa B, Bonifacio E, Ciurnelli R et al. NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL. Br J Haematol 2010; 151: 404-406.
-
(2010)
Br J Haematol
, vol.151
, pp. 404-406
-
-
Sportoletti, P.1
Baldoni, S.2
Cavalli, L.3
Del Papa, B.4
Bonifacio, E.5
Ciurnelli, R.6
-
67
-
-
84855860383
-
NOTCH1 mutations in CLL associated with trisomy 12
-
Balatti V, Bottoni A, Palamarchuk A, Alder H, Rassenti LZ, Kipps TJ et al. NOTCH1 mutations in CLL associated with trisomy 12. Blood 2012; 119: 329-331.
-
(2012)
Blood
, vol.119
, pp. 329-331
-
-
Balatti, V.1
Bottoni, A.2
Palamarchuk, A.3
Alder, H.4
Rassenti, L.Z.5
Kipps, T.J.6
-
68
-
-
84857739865
-
NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL
-
Del Giudice I, Rossi D, Chiaretti S, Marinelli M, Tavolaro S, Gabrielli S et al. NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL. Haematologica 2011; 97: 437-441.
-
(2011)
Haematologica
, vol.97
, pp. 437-441
-
-
Del Giudice, I.1
Rossi, D.2
Chiaretti, S.3
Marinelli, M.4
Tavolaro, S.5
Gabrielli, S.6
-
69
-
-
79551686422
-
Oncogenically active MYD88 mutations in human lymphoma
-
Ngo VN, Young RM, Schmitz R, Jhavar S, Xiao W, Lim KH et al. Oncogenically active MYD88 mutations in human lymphoma. Nature 2011; 470: 115-119.
-
(2011)
Nature
, vol.470
, pp. 115-119
-
-
Ngo, V.N.1
Young, R.M.2
Schmitz, R.3
Jhavar, S.4
Xiao, W.5
Lim, K.H.6
-
71
-
-
84860782819
-
SF3B1 mutations in primary myelofibrosis: Clinical histopathology and genetic correlates among 155 patients
-
e-pub ahead of print 8 November 2011 doi:10.1038/leu.2011.320
-
Lasho TL, Finke CM, Hanson CA, Jimma T, Knudson RA, Ketterling RP et al. SF3B1 mutations in primary myelofibrosis: clinical, histopathology and genetic correlates among 155 patients. Leukemia 2011; e-pub ahead of print 8 November 2011; doi:10.1038/leu.2011.320.
-
(2011)
Leukemia
-
-
Lasho, T.L.1
Finke, C.M.2
Hanson, C.A.3
Jimma, T.4
Knudson, R.A.5
Ketterling, R.P.6
|