Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity

Toxicology in Vitro

Volumn 23, Issue 6, 2009, Pages 1179-1187

  Yoshikawa, Yukitaka ^a   Hosomi, Hiroko ^a   Fukami, Tatsuki ^a   Nakajima, Miki ^a   Yokoi, Tsuyoshi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

CYP3A4; Cytotoxicity; Reactive oxygen species; RNA interference; Superoxide dismutase 2

Indexed keywords

ADENOVIRUS VECTOR; ALBENDAZOLE; CARBAMAZEPINE; CYTOCHROME P450 3A4; DANTROLENE; DAPSONE; FLUTAMIDE; ISONIAZID; MANGANESE SUPEROXIDE DISMUTASE; NIFEDIPINE; REACTIVE OXYGEN METABOLITE; ROSIGLITAZONE; SHORT HAIRPIN RNA; SULFAMETHOXAZOLE; TRAZODONE; TROGLITAZONE; ZIDOVUDINE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER MITOCHONDRION; LIVER TOXICITY; MITOCHONDRIAL TOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; RNA INTERFERENCE;

ADENOVIRIDAE; ANIMALS; CELL LINE; CELL SURVIVAL; CYTOCHROME P-450 ENZYME SYSTEM; DRUG EVALUATION, PRECLINICAL; GENETIC VECTORS; HUMANS; LIPID PEROXIDATION; MICE; OXIDATIVE STRESS; PHARMACEUTICAL PREPARATIONS; RATS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SUPEROXIDE DISMUTASE;

ADENOVIRIDAE; RATTUS;

EID: 68049090823     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.05.024     Document Type: Article

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