Nano chitosan peptide as a potential therapeutic carrier for retinal delivery to treat age-related macular degeneration

Molecular Vision

Volumn 18, Issue , 2012, Pages 2300-2308

  Jayaraman, Melamangalam S ^a   Bharali, Dhruba J ^a   Sudha, Thangirala ^a   Mousa, Shaker A ^a  

^a ALBANY COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN; NANOPARTICLE; PROTEIN TYROSINE KINASE; SERINE; THREONINE; TYROSINE;

AMINO ACID SEQUENCE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIGHT SCATTERING; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PRIORITY JOURNAL; RETINA CELL; RETINA MACULA AGE RELATED DEGENERATION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

BIOLOGICAL TRANSPORT; CELL LINE; CHITOSAN; DRUG CARRIERS; EPITHELIAL CELLS; HUMANS; MACULAR DEGENERATION; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR STRUCTURE; NANOSTRUCTURES; OLIGOPEPTIDES; PROTEIN-TYROSINE KINASES; RETINAL PIGMENT EPITHELIUM; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WATER;

EID: 84865814615     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Friedman DS, O'Colmain BJ, Munoz B, Tomany SC, McCarty C, de Jong PT, Nemesure B, Mitchell P, Kempen J. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 2004; 122:564-72. [PMID: 15078675]
2. de Jong PT. Age-related macular degeneration. N Engl J Med 2006; 355:1474-85. [PMID: 17021323]
3. Richter C. Insight into age-related macular degeneration: new vision in sight. Cell Death Differ 2001; 8:207-9. [PMID: 11319602]
4. Lu L, Hackett SF, Mincey A, Lai H, Campochiaro PA. Effects of different types of oxidative stress in RPE cells. J Cell Physiol 2006; 206:119-25. [PMID: 15965958]
5. Wong WT, Kam W, Cunningham D, Harrington M, Hammel K, Meyerle CB, Cukras C, Chew EY, Sadda SR, Ferris FL. Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial. Invest Ophthalmol Vis Sci 2010; 51:6131-9. [PMID: 20574018]
6. Primo SA. Implantable miniature telescope: lessons learned. Optometry 2010; 81:86-93. [PMID: 20152782]
7. Hudson HL, Lane SS, Heier JS, Stulting RD, Singerman L, Lichter PR, Sternberg P, Chang DF. Implantable miniature telescope for the treatment of visual acuity loss resulting from end-stage age-related macular degeneration: 1-year results. Ophthalmology 2006; 113:1987-2001. [PMID: 16989902]
8. Laude A, Cackett PD, Vithana EN, Yeo IY, Wong D, Koh AH, Wong TY, Aung T. Polypoidal choroidal vasculopathy and neovascular age-related macular degeneration: same or different disease? Prog Retin Eye Res 2010; 29:19-29. [PMID: 19854291]
9. Brown SB, Mellish KJ. Verteporfin: a milestone in opthalmology and photodynamic therapy. Expert Opin Pharmacother 2001; 2:351-61. [PMID: 11336591]
10. Hunt DW, Margaron P. Status of therapies in development for the treatment of age-related macular degeneration. IDrugs 2003; 6:464-9. [PMID: 12789601]
11. Ferrara N, Damico L, Shams N, Lowman H, Kim R. Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration. Retina 2006; 26:859-70. [PMID: 17031284]
12. Colquitt JL, Jones J, Tan SC, Takeda A, Clegg AJ, Price A. Ranibizumab and pegaptanib for the treatment of agerelated macular degeneration: a systematic review and economic evaluation. Health Technol Assess 2008; 12:iiiiv. [PMID: 18462575]
13. Waisbourd M, Goldstein M, Loewenstein A. National survey of the ophthalmic use of anti-vascular endothelial growth factor drugs in Israel. Isr Med Assoc J 2011; 13:141-6. [PMID: 21608333]
14. Meyer CH, Holz FG. Preclinical aspects of anti-VEGF agents for the treatment of wet AMD: ranibizumab and bevacizumab. Eye (Lond) 2011; 25:661-72. [PMID: 21455242]
15. Cashman SM, Bowman L, Christofferson J, Kumar-Singh R. Inhibition of choroidal neovascularization by adenovirusmediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD. Invest Ophthalmol Vis Sci 2006; 47:3496-504. [PMID: 16877421]
16. Paolicelli P, de la Fuente M, Sanchez A, Seijo B, Alonso MJ. Chitosan nanoparticles for drug delivery to the eye. Expert Opin Drug Deliv 2009; 6:239-53. [PMID: 19290841]
17. Thrimawithana TR, Young S, Bunt CR, Green C, Alany RG. Drug delivery to the posterior segment of the eye. Drug Discov Today 2011; 16:270-7. [PMID: 21167306]
18. Gaudana R, Ananthula HK, Parenky A, Mitra AK. Ocular drug delivery. AAPS J 2010; 12:348-60. [PMID: 20437123]
19. Han HD, Mangala LS, Lee JW, Shahzad MM, Kim HS, Shen D, Nam EJ, Mora EM, Stone RL, Lu C, Lee SJ, Roh JW, Nick AM, Lopez-Berestein G, Sood AK. Targeted gene silencing using RGD-labeled chitosan nanoparticles. Clin Cancer Res 2010; 16:3910-22. [PMID: 20538762]
20. Kumar A, Jena PK, Behera S, Lockey RF, Mohapatra S. Multifunctional magnetic nanoparticles for targeted delivery. Nanomedicine 2010; 6:64-9. [PMID: 19446653]
21. de Campos AM, Diebold Y, Carvalho EL, Sanchez A, Alonso MJ. Chitosan nanoparticles as new ocular drug delivery systems: in vitro stability, in vivo fate, and cellular toxicity. Pharm Res 2004; 21:803-10. [PMID: 15180338]
22. Enríquez de Salamanca A, Diebold Y, Calonge M, Garcia-Vazquez C, Callejo S, Vila A, Alonso MJ. Chitosan nanoparticles as a potential drug delivery system for the ocular surface: toxicity, uptake mechanism and in vivo tolerance. Invest Ophthalmol Vis Sci 2006; 47:1416-25. [PMID: 16565375]
23. Mochizuki M, Yamagata N, Philp D, Hozumi K, Watanabe T, Kikkawa Y, Kadoya Y, Kleinman HK, Nomizu M. Integrin-dependent cell behavior on ECM peptide-conjugated chitosan membranes. Biopolymers 2007; 88:122-30. [PMID: 17236208]
24. Alonso MJ, Sanchez A. The potential of chitosan in ocular drug delivery. J Pharm Pharmacol 2003; 55:1451-63. [PMID: 14713355]
25. Rajendran NN, Natrajan R, Kumar RS, Selvaraj S. Acyclovirloaded chitosan nanoparticles for ocular delivery. Asian J Pharmaceutics 2010; 4:220-6.
26. Feng W, Yasumura D, Matthes MT, LaVail MM, Vollrath D. Mertk triggers uptake of photoreceptor outer segments during phagocytosis by cultured retinal pigment epithelial cells. J Biol Chem 2002; 277:17016-22. [PMID: 11861639]
27. Mallavarapu M, Finnemann SC. Neural retina and MerTKindependent apical polarity of alphavbeta5 integrin receptors in the retinal pigment epithelium. Adv Exp Med Biol 2010; 664:123-31. [PMID: 20238010]
28. Qin S, Rodrigues GA. Roles of alphavbeta5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis. Exp Eye Res 2012; 94:63-70. [PMID: 22138557]
29. Artçanuthurry V, Grelac F, Maclouf J, Martin-Cramer E, Levy-Toledano S. Serine/threonine dephosphorylation may be involved in tyrosine phosphorylation: a new mode of signal transduction in platelets. Semin Thromb Hemost 1996; 22:317-26. [PMID: 8944416]
30. Taylor SS, Radzio-Andzelm E, Hunter T. How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein-tyrosine kinase. FASEB J 1995; 9:1255-66. [PMID: 7557015]
31. Onoda T, Iinuma H, Sasaki Y, Hamada M, Isshiki K, Naganawa H, Takeuchi T, Tatsuta K, Umezawa K. Isolation of a novel tyrosine kinase inhibitor, lavendustin A, from Streptomyces griseolavendus. J Nat Prod 1989; 52:1252-7. [PMID: 2614420]
32. Dung TH, Lee SR, Han SD, Kim SJ, Ju YM, Kim MS, Yoo H. Chitosan-TPP nanoparticle as a release system of antisense oligonucleotide in the oral environment. J Nanosci Nanotechnol 2007; 7:3695-9. [PMID: 18047039]
33. Gaspar VM, Sousa F, Queiroz JA, Correia IJ. Formulation of chitosan-TPP-pDNA nanocapsules for gene therapy applications. Nanotechnology 2011; 22:015101. [PMID: 21135452]
34. Quan H, Zhu F, Han X, Xu Z, Zhao Y, Miao Z. Mechanism of anti-angiogenic activities of chitooligosaccharides may be through inhibiting heparanase activity. Med Hypotheses 2009; 73:205-6. [PMID: 19342181]
35. Yamagata N, Hozumi K, Kikkawa Y, Nomizu M. Peptide Mosaic Chitosan Membranes Promote Diverse Biological Functions. 4th International Peptide Symposium in conjunction with the 7th Australian Peptide Conference and the 2nd Asia-Pacific International Peptide Symposium; 2007 Oct 21-25; Cairns, Australia.
36. Zhang P, Nelson S, Summer WR, Spitzer JA. Serine/threonine phosphorylation in cellular signaling for alveolar macrophage phagocytic response to endotoxin. Shock 2000; 13:34-40. [PMID: 10638667]
37. Szeto HH. Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J 2006; 8:E521-31. [PMID: 17025271]
38. Vi L, de Lasa C, DiGuglielmo GM, Dagnino L. Integrinlinked kinase is required for TGF-beta1 induction of dermal myofibroblast differentiation. J Invest Dermatol 2011; 131:586-93. [PMID: 21150927]
39. Wang Z, Dillon J, Gaillard ER. Antioxidant properties of melanin in retinal pigment epithelial cells. Photochem Photobiol 2006; 82:474-9. [PMID: 16613501]
40. Seagle BL, Rezai KA, Kobori Y, Gasyna EM, Rezaei KA, Norris JR Jr. Melanin photoprotection in the human retinal pigment epithelium and its correlation with light-induced cell apoptosis. Proc Natl Acad Sci USA 2005; 102:8978-83. [PMID: 15951427]
41. Schraermeyer U, Kopitz J, Peters S, Henke-Fahle S, Blitgen-Heinecke P, Kokkinou D, Schwarz T, Bartz-Schmidt KU. Tyrosinase biosynthesis in adult mammalian retinal pigment epithelial cells. Exp Eye Res 2006; 83:315-21. [PMID: 16579986]