Association between environmental exposure to benzene and oxidative damage to nucleic acids in children

Medicina del Lavoro

Volumn 103, Issue 5, 2012, Pages 324-337

  Andreoli, Roberta ^a,b   Protano, Roberta ^c   Manini, Paola ^a   De Palma, G ^d   Goldoni, M ^a,b   Petyx, Marta ^e   Rondinone, Bruna Maria ^e   Vitali, M ^c   Mutti, A ^a  

^a Nephrology and Health Sciences ^*  (Italy)

^b UNIVERSITY OF PARMA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF BRESCIA   (Italy)

^e DEPARTMENT OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE   (Italy)

Author keywords

Benzene exposure; Nucleic acid oxidation; S phenylmercapturic acid

Indexed keywords

8 HYDROXYGUANINE; 8 HYDROXYGUANOSINE; 8 OXO 7 HYDRODEOXYGUANOSINE; 8-HYDROXYGUANINE; 8-HYDROXYGUANOSINE; 8-OXO-7-HYDRODEOXYGUANOSINE; ACETYLCYSTEINE; BENZENE; BIOLOGICAL MARKER; COTININE; DEOXYGUANOSINE; DNA; DRUG DERIVATIVE; GUANINE; GUANOSINE; MUCONIC ACID; N ACETYL S PHENYLCYSTEINE; RNA; S-PHENYL-N-ACETYLCYSTEINE; SORBIC ACID;

AIR POLLUTANT; ARTICLE; CHILD; CLINICAL TRIAL; COMPARATIVE STUDY; DNA DAMAGE; DRUG EFFECT; ENVIRONMENTAL MONITORING; FEMALE; HUMAN; ITALY; MALE; MULTICENTER STUDY; OXIDATIVE STRESS; PASSIVE SMOKING; RURAL POPULATION; SUBURBAN POPULATION; URBAN POPULATION; URINE;

ACETYLCYSTEINE; AIR POLLUTANTS; BENZENE; BIOLOGICAL MARKERS; CHILD; COTININE; DEOXYGUANOSINE; DNA; DNA DAMAGE; ENVIRONMENTAL MONITORING; FEMALE; GUANINE; GUANOSINE; HUMANS; ITALY; MALE; OXIDATIVE STRESS; RNA; RURAL POPULATION; SORBIC ACID; SUBURBAN POPULATION; TOBACCO SMOKE POLLUTION; URBAN POPULATION;

EID: 84865782087     PISSN: 00257818     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. ACGIH 2010: American Conference of Governmental Industrial Hygienists (ACGIH) TLVs and BEIs based on the documentation of the threshold limit values for chemical substances and physical agents and biological indices ACGIH, Cincinnati, OH 2010
2. Andreoli R, Manini P, De Palma G, et al: Quantitative determination of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8- dihydroguanosine, and their non-oxidized forms: daily concentration profile in healthy volunteers. Biomarkers 2009; 15: 221-231
3. Andreoli R, Mutti A, Goldoni M, et al: Reference ranges of urinary biomarkers of oxidized guanine in (2'- deoxy)ribonucleotides and nucleic acids. Free Radic Biol Med 2011; 50: 254-261
4. Avogbe PH, Ayi-Fanou L, Autrup H, et al: Ultrafine particulate matter and high-level benzene urban air pollution in relation to oxidative DNA damage. Carcinogenesis 2005; 26: 613-620
5. Barreto G, Madureira D, Capani F, et al: The role of cathecols and free radicals in benzene toxicity: an oxidative DNA damage pathway. Environ Mol Mutagen 2009; 50: 771-780
6. Benowitz NL, Perez-Stable EJ, Fong I, et al: Ethnic differences in N-glucuronidation of nicotine and cotinine. J Pharmacol Exp Ther 1999; 291: 1196-1203
7. Bessho T, Tano K, Kasai H, et al: Evidence for two DNA repair enzymes for 8-hydroxyguanine (7,8-dihydro- 8-oxoguanine) in human cells. J Biol Chem 1993; 268: 19416-19421
8. Bono R, Traversi D, Maestri L, et al: Urban air and tobacco smoke in benzene exposure in a cohort of traffic police-men. Chem Biol Interact 2005; 153-154: 239- 242
9. Buthbumrung N, Mahidol C, Navasumrit P, et al: Oxidative DNA damage and influence of genetic polymorphisms among urban and rural schoolchildren exposed to benzene. Chemico-Biological Interactions 2008; 172: 185-194
10. Campo L, Cattaneo A, Consonni D, et al: Urinary methyl tert-butyl ether and benzene as biomarkers of exposure to urban traffic. Environment International 2011; 37: 404-411
11. Cooke MS, Evans MD, Dizdaroglu M, Lunec J: Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J 2003; 17: 1195-1214
12. Darrall KG, Figgins JA, Brown RD, Phillips GF. Determination of benzene and associated volatile compounds in mainstream cigarette smoke. Analyst 1998; 123: 1095-1101
13. Domino EF, Hornbach E, Demana T: The nicotine content of common vegetables. N Engl J Med 1993; 329: 437
14. Dor F, Dab W, Empereur-Bissonnet P, Zmirou D. Validity of biomarkers in environmental health studies: the case of PAHs and benzene. Crit Rev Toxicol 1999; 29: 129-68
15. Effect of air pollution on children's health and development, WHO 2005.
16. European Commission, 1997: European Commission Council Directive 97/42/EC of 27 June 1997 amending for the first time Directive 90/394/EEC on protecting workers from risks related to exposure to carcinogens at work [Sixth Individual Directive according to Art. 16(1) of Directive 89/391/EEC]. Official Journal of the European Communities No. L179, 08.07.1997 European Commission, Brussels, Belgium
17. European Commission, 2005: EU Fuel Quality Monitoring- 2004 Summary Report. Final report produced for the DG Environment Nikolas Hill, AEA Technology Environment, December. Brussels, Belgium: European Commission; 2005. Available on line at: http://ec.europa.eu/environment/air/pdf/fqm-summary -2004.pdf [last accessed 12 June 2010])
18. European Commission. Directive 2000/69/EC of the European Parliament and of the Council of 16 November 2000 relating to limit values for benzene and carbon monoxide in ambient air. 2000, Brussels, Belgium: European Commission. Available online at: http://eurlex. europa.eu/LexUriServ/LexUriServ.do?uri= CELEX: 32000L0069:EN:NOT. Accessed on 26-3-2012
19. Evans MD, Cooke MS: Factors contributing to the outcome of oxidative damage to nucleic acids. BioEssays 2004; 26: 533-542
20. Evans MD, Olinski R, Loft S, Cooke MS: European Standards Committee on Urinary (DNA) Lesion Analysis Toward consensus in the analysis of urinary 8-oxo7,8- dihydro-2 -deoxyguanosine as a noninvasive biomarker of oxidative stress. FASEB J 2010; 24: 1249-1260
21. Fracasso ME, Doria D, Bartolucci GB, et al: Low air levels of benzene: correlation between biomarkers of exposure and genotoxic effects. Toxicol Lett 2010; 192: 22-28
22. Fustinoni S, Campo L, Satta G, et al: Environmental and lifestyle factors affect benzene uptake biomonitoring of residents near a petrochemical plant. Environment International 2012; 39: 2-7
23. Fustinoni S, Consonni D, Campo L, et al: Monitoring low benzene exposure: comparative evaluation of urinary biomarkers, influence of cigarette smoking, and genetic polymorphisms. Cancer Epidemiol Biomarkers Prev 2005; 14: 2237-2244
24. Imbriani M, Ghittori S: Gases and organic solvents in urine as biomarkers of occupational exposure: a review. Int. Arch Occup Environ Health 2005; 78: 1-19
25. International Agency for Research on Cancer: Benzene. Some Industrial Chemicals and Dyestuffs. Lyon, 1982 (IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, no 29)
26. Kroll MH, Chesler R, Hagengruber C, et al: Automated determination of urinary creatinine without sample dilution: theory and practice. Clin Chem 1986; 32: 446-452
27. Lan Q, Zhang L, Li G, Vermeulen, et al: Hematotoxicity in workers exposed to low levels of benzene. Science 2004 Dec 3; 306: 1774-1776
28. Loft S, Poulsen HE: Cancer risk and oxidative DNA damage in man. J Mol Med 1996; 74: 297-312
29. Loft S, Poulsen HE: Markers of oxidative damage to DNA: antioxidants and molecular damage. Methods Enzymol 1999; 300: 166-184
30. Lovreglio P, D'Errico MN, Fustinoni S, et al: Biomarkers of internal dose for assessment of environmental exposure to benzene. J Environ Monit 2011; 13: 2921- 2928
31. Manini P, De Palma G, Andreoli R, et al: Biological monitoring of low benzene exposure in Italian traffic policemen.Toxicol Lett 2008; 181: 25-30
32. Manini P, De Palma G, Andreoli R, et al: Environmental and biological monitoring of benzene exposure in a cohort of Italian taxi drivers. Toxicol Lett 2006; 167: 142-151
33. Manini P, De Palma G, Andreoli R, et al: Occupational exposure to low levels of benzene: biomarkers of exposure and nucleic acid oxidation and their modulation by polymorphic xenobiotic metabolizing enzymes. Toxicol Lett 2010; 193(3): 229-235
34. Nunomura A, Honda K, Takeda A, et al: Oxidative damage to RNA in neurodegenerative diseases. J Biomed Biotechnol 2006; 82323
35. Olinski R, Siomek A, Rozalski R, et al: Oxidative damage to DNA and antioxidant status in aging and agerelated diseases. Acta Biochim Pol 2007; 54: 11-26
36. Pérez-Stable EJ, Herrera B, Jacob P 3rd, Benowitz NL: Nicotine metabolism and intake in black and white smokers. JAMA 1988; 280: 152-156
37. Pilger A, Rudiger HW: 8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures. Int Arch Occup Environ Health 2006; 80: 1-15
38. Protano C, Andreoli R, Manini P, et al: A tobacco-related carcinogen: assessing the impact of smoking behaviours of cohabitants on benzene exposure in children. Tob Control 2012; 21: 325-329
39. Protano C, Andreoli R, Manini P, Vitali M: How home-smoking habits affect children: a cross-sectional study using urinary cotinine measurement in Italy. Int J Public Health 2012 March 21 [Epub ahead of print]
40. Protano C, Guidotti M,Manini P, et al: Benzene exposure in childhood: Role of living environments and assessment of available tools. Environment International 2010; 36: 779-787
41. Shigenaga MK, Gimeno CJ, Ames BN: Urinary 8-hydroxy- 2- deoxyguanosine as a biological marker of in vivo oxidative DNA damage. Proc Natl Acad Sci USA 1989; 86: 9697-9701
42. SIMLII: Linee guida per il monitoraggio biologico. Mutti A (coordinatore), De Palma G, Manini P, et al. Pavia: PI-ME Editrice, 2006
43. Smith MT: Advances in understanding benzene health effects and susceptibility. Annu Rev Public Health 2010; 31: 133-148
44. Sørensen M, Skov H, Autrup, H, et al: Urban benzene exposure and oxidative DNA damage: influence of genetic polymorphisms in metabolism genes. Sci Total Environ 2003; 309: 69-80
45. Staessen JA, Nawrot T, Hond ED, et al: Renal function, cytogenetic measurements, and sexual development in adolescents in relation to environmental pollutants: a feasibility study of biomarkers. Lancet 2001; 357: 1660-1669
46. Svecova V, Rossner P Jr, Dostal M, et al: Urinary 8-oxodeoxyguanosine levels in children exposed to air pollutants. Mutation Research 2009; 662: 37-43
47. Tsuzuki T, Egashira A, Igarashi H, et al: Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGuoTPase. Proc Natl Acad Sci USA 2001; 98: 11456-11461
48. US Environmental Protection Agency (US EPA), 1998. Carcinogenic effects of benzene: An update. EPA/600/P-97/001F. Washington DC: Office of Research and Development. http://www.epa.gov/ncea/ pdfs/benzenef.pdf. Available at: http://whqlibdoc.who. int/publications/2007/9789241563413-eng.pdf [last accessed 24 January 2012]
49. Vitali M, Ensabella F, Stella D, et al: Exposure to organic solvents among handicraft car painters: a pilot study in Italy. Ind Health 2006; 44: 310-317
50. Weimann A, Belling D, Poulsen HE: Quantification of 8-oxoguanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry. Nucleic Acids Res 2002; 30: E7