Occupational exposure to low levels of benzene: Biomarkers of exposure and nucleic acid oxidation and their modulation by polymorphic xenobiotic metabolizing enzymes

Toxicology Letters

Volumn 193, Issue 3, 2010, Pages 229-235

  Manini, Paola ^a   De Palma, Giuseppe ^b   Andreoli, Roberta ^a   Mozzoni, Paola ^a   Poli, Diana ^a   Goldoni, Matteo ^a   Petyx, Marta ^c   Apostoli, Pietro ^b   Mutti, Antonio ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c ISPESL   (Italy)

Author keywords

8 Oxo 7,8 dihydro 2 deoxyguanosine; 8 Oxo 7,8 dihydroguanine; 8 Oxo 7,8 dihydroguanosine; Genetic polymorphisms; S Phenylmercapturic acid; t,t Muconic acid

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 HYDROXYGUANINE; 8 OXO 7,8 DIHYDROGUANOSINE; ACETYLCYSTEINE DERIVATIVE; BENZENE; BIOLOGICAL MARKER; COTININE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; GUANOSINE DERIVATIVE; MUCONIC ACID; N ACETYL S PHENYLCYSTEINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG;

ADULT; AGE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATIONAL STUDY; ENZYME ACTIVITY; FEMALE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; ITALY; LIQUID CHROMATOGRAPHY; MALE; NUCLEIC ACID METABOLISM; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEX DIFFERENCE; SMOKING HABIT; TANDEM MASS SPECTROMETRY; URINARY EXCRETION; XENOBIOTIC METABOLISM;

ACETYLCYSTEINE; ADULT; BENZENE; BIOLOGICAL MARKERS; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; MIDDLE AGED; NAD(P)H DEHYDROGENASE (QUINONE); NUCLEIC ACIDS; OCCUPATIONAL EXPOSURE; OXIDATION-REDUCTION; POLYMORPHISM, GENETIC; REGRESSION ANALYSIS; SORBIC ACID; XENOBIOTICS;

EID: 77249165476     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.01.013     Document Type: Article

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