The effect of thiocolchicoside on cerebral vasospasm following experimental subarachnoid hemorrhage in the rabbit

Acta Neurochirurgica

Volumn 154, Issue 8, 2012, Pages 1431-1436

  Kertmen, Hayri ^a   Gürer, Bora ^a   Yilmaz, Erdal Resit ^a   Arikok, Ata Türker ^a   Demirci, Adnan ^a   Gökyaprak, Salih Metin ^b   Sekerci, Zeki ^a  

^a DISKAPI YILDIRIM BEYAZIT TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b MINISTRY OF HEALTH   (Turkey)

Author keywords

GABA; Rabbit; Subarachnoid hemorrhage; Thiocolchicoside; Vasospasm

Indexed keywords

MUSCORIL; THIOCOLCHICOSIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL WALL THICKNESS; ARTICLE; BASILAR ARTERY; BRAIN VASOSPASM; CONTROLLED STUDY; DRUG EFFECT; DRUG RESPONSE; EXPERIMENTAL RABBIT; GABAERGIC TRANSMISSION; HISTOLOGY; MALE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SUBARACHNOID HEMORRHAGE;

ANIMALS; BASILAR ARTERY; COLCHICINE; DISEASE MODELS, ANIMAL; MALE; MUSCLE, SMOOTH, VASCULAR; RABBITS; SUBARACHNOID HEMORRHAGE; VASOSPASM, INTRACRANIAL;

EID: 84865774723     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-012-1420-3     Document Type: Article

References (22)

1. Alborch E, Torregrosa G, Terrasa JC, Estrada C (1984) GABA receptors mediate cerebral vasodilation in the unanesthetized goat. Brain Res 321:103-110 (Pubitemid 15176899)
2. Anwar N, Mason DF (1982) Two actions of gamma-aminobutyric acid on the responses of the isolated basilar artery from the rabbit. Br J Pharmacol 75:177-181 (Pubitemid 12200766)
3. Artusi M, Santi P, Colombo P, Junginger HE (2003) Buccal delivery of thiocolchicoside: In vitro and in vivo permeation studies. Int J Pharm 250:203-213 (Pubitemid 35447950)
4. Balduini W, Cimino M, Depoortere H, Cattabeni F (1999) Characterization of [3H]thiocolchicoside binding sites in rat spinal cord and cerebral cortex. Eur J Pharmacol 376:149-157 (Pubitemid 29320180)
5. Balduini W, De Angelis V, Mazzoni E, Depoortere H, Cattabeni F, Cimino M (2001) Autoradiographic localization of [3H]thiocolchicoside binding sites in the rat brain and spinal cord. Neuropharmacology 40:1044-1049 (Pubitemid 32530611)
6. Belen D, Besalti O, Yiitkanli K, Kösemehmetolu K, Simsek S, Bolay H (2007) Leflunomide prevents vasospasm secondary to subarachnoid haemorrhage. Acta Neurochir 149:1041-1047 (Pubitemid 47547153)
7. Biziere K, Huguet F, Narcisse G, Breteau M (1981) Affinity of thiocolchicoside and thiocolchicoside analogues for the postsynaptic GABA receptor site. Eur J Pharmacol 75:167-168 (Pubitemid 11026502)
8. Carta M, Murru L, Botta P, Talani G, Sechi G, De Riu P, Sanna E, Biggio G (2006) The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system. Neuropharmacology 51:805-815 (Pubitemid 44308341)
9. Cetas JS, Lee DR, Alkayed NJ, Wang R, Iliff JJ, Heinricher MM (2009) Brainstem control of cerebral blood flow and application to acute vasospasm following experimental subarachnoid hemorrhage. Neuroscience 163:719-729
10. Cimino M, Marini P, Cattabeni F (1996) Interaction of thiocolchicoside with [3H]strychnine binding sites in rat spinal cord and brainstem. Eur J Pharmacol 318:201-204 (Pubitemid 27033224)
11. Edvinsson L, Krause DN (1979) Pharmacological characterization of GABA receptors mediating vasodilation of verebral arteries in vitro. Brain Res 173:89-97 (Pubitemid 9242073)
12. Fujiwara M, Muramatsu I (1975) Gamma-aminobutyric acid receptor on vascular smooth muscle of dog cerebral arteries. Br J Pharmacol 55:561-562
13. Gelmi ML, Fontana G, Pocar D, Pontremoli G, Pellegrino S, Bombardelli E, Riva A, Balduini W, Carloni S, Cimino M (2007) Novel 3-O-glycosyl-3- demethylthiocolchicines as ligands for glycine and gamma-aminobutyric acid receptors. Med Chem 50:2245-2248 (Pubitemid 46683077)
14. Imai H, Okuno T, Wu JY, Lee TJ (1991) GABAergic innervation in cerebral blood vessels: An immunohistochemical demonstration of L-glutamic acid decarboxylase and GABA transaminase. J Cereb Blood Flow Metab 11:129-134
15. Janbroers JM (1987) Review of the toxicology, pharmacodynamics and pharmacokinetics of thiocolchicoside, a GABA-agonist muscle relaxant with anti-inflammatory and analgesic action. Acta Ther 13:221-250 (Pubitemid 17057153)
16. Kassell NF, Sasaki T, Colohan AR, Nazar G (1985) Cerebral vasospasm following aneurysmal subarachnoid hemorrhage. Stroke 16:562-572 (Pubitemid 15007226)
17. Kolias AG, Sen J, Belli A (2009) Pathogenesis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage: Putative mechanisms and novel approaches. J Neurosci Res 87:1-11
18. Krause DN, Wong E, Degener P, Roberts E (1980) GABA receptors in bovine cerebral blood vessels: Binding studies with [3H] muscimol. Brain Res 185:51-57 (Pubitemid 10128655)
19. Marbacher S, Fandino J, Kitchen ND (2010) Standard intracranial in vivo animal models of delayed cerebral vasospasm. Br J Neurosurg 24:415-434
20. Perucca E, Poitou P, Pifferi G (1995) Comparative pharmacokinetics and bioavailability of two oral formulations of thiocolchicoside, a GABA-mimetic muscle relaxant drug, in normal volunteers. Eur J Drug Metab Pharmacokinet 24:301-305 (Pubitemid 26128619)
21. Schousboe A (1999) Pharmacologic and therapeutic aspects of the developmentally regulated expression of GABA(A) and GABA(B) receptors: Cerebellar granule cells as a model system. Neurochem Int 34:373-377 (Pubitemid 29240633)
22. Vorkapic P, Bevan JA, Bevan RD (1991) Two indices of functional damage of the artery wall parallel the time course of irreversible narrowing in experimental vasospasm in the rabbit. Blood Vessel 28:179-182