Autoradiographic localization of [3H]thiocolchicoside binding sites in the rat brain and spinal cord

Neuropharmacology

Volumn 40, Issue 8, 2001, Pages 1044-1049

  Balduini, Walter ^a   De Angelis, Valerio ^a   Mazzoni, Erika ^a   Depoortere, Henri ^b   Cattabeni, Flaminio ^c   Cimino, Mauro ^a  

^a UNIVERSITY OF URBINO   (Italy)

^b SANOFI   (France)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

GABA receptors; Glycine receptors; Radioreceptor binding; Rat; Spinal cord; Strychnine; Thiocolchicoside

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; MUSCIMOL; STRYCHNINE; THIOCOLCHICOSIDE; COLCHICINE; DRUG DERIVATIVE;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BRAIN; BRAIN CORTEX; CONTROLLED STUDY; DRUG BINDING; DRUG BINDING SITE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; SPINAL CORD DORSAL HORN; SYNAPTIC MEMBRANE; TISSUE DISTRIBUTION; ANIMAL; BINDING SITE; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; AUTORADIOGRAPHY; BINDING SITES; BRAIN; COLCHICINE; GAMMA-AMINOBUTYRIC ACID; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SPINAL CORD; STRYCHNINE; SYNAPTIC MEMBRANES;

EID: 0034743783     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00023-5     Document Type: Article

References (27)

1. 3H]thiocolchicoside binding sites in rat spinal cord and cerebral cortex
2. GABAergic terminals are presynaptic to primary afferent terminals in the substantia gelatinosa of the rat spinal cord
3. Muscimol binding in rat brain: Association with synaptic GABA receptors
4. Immunochemical identification of the alpha 1- and alpha 3-subunits of the GABAA-receptor in rat brain
5. Affinity of thiocolchicoside and thiocolchicoside analogues for the postsynaptic GABA receptor site
6. Le thiocolchicoside un agoniste des récepteurs GABAergiques
7. Laminar compartmentalization of GABAA-receptor subtypes in the spinal cord: An immunohistochemical study
8. Interaction of thiocolchicoside with [3H]strychnine binding sites in rat spinal cord and brainstem
9. Benzodiazepine receptors in the human spinal cord: A detailed anatomical and pharmacological study
10. Thiocolchicoside: A muscle relaxant devoid of sedative effect
11. Stereospecific interaction of bicuculline with specific [3H]strychnine binding to rat spinal cord synaptosomal membranes
12. Characterization of the binding of [3H]SR 95531, a GABAA antagonist, to rat brain membranes
13. Review of the toxicology, pharmacodynamics and pharmacokinetics of thiocolchicoside, a GABA-agonist muscle relaxant with anti-inflammatory and analgesic actions
14. GABAA-receptors: Drug binding profile and distribution of receptors containing the alpha 2-subunit in situ
15. Strychnine: A potent competitive antagonist of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons
16. Immunocytochemical localization of glutamate decarboxylase in rat spinal cord
17. gamma-Aminobutyric acid receptor binding in mammalian brain. Heterogeneity of binding sites
18. 3H]bicuculline methochloride binding to low-affinity gamma-aminobutyric acid receptor sites
19. GABAA receptor subtypes: Autoradiographic comparison of GABA, benzodiazepine, and convulsant binding sites in the rat central nervous system
20. High affinity GABA receptors - Autoradiographic localization
21. B receptors present on primary afferent terminals of the spinal cord?
22. A-benzodiazepine receptors produced in transfected cells
23. Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes
24. Antagonism of ligand-gated ion channel receptors: Two domains of the glycine receptor alpha subunit form the strychnine-binding site
25. CL 218872 binding to benzodiazepine receptors in rat spinal cord: Modulation by gamma-aminobutyric acid and evidence for receptor heterogeneity
26. Radiohistochemical localization of benzodiazepine receptors in rat brain
27. Multiple benzodiazepine receptor localization by light microscopic radiohistochemistry