Directed evolution of the peroxidase activity of a de novo-designed protein

Protein Engineering, Design and Selection

Volumn 25, Issue 9, 2012, Pages 445-451

  Patel, Shona C ^a,c   Hecht, Michael H ^b  

^a Princeton University   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

binary code; directed evolution; peroxidase; protein design; synthetic biology

Indexed keywords

BIOCHEMICAL CHARACTERIZATION; COMBINATORIAL LIBRARY; DIRECTED EVOLUTION; FOLDED PROTEINS; HEME COFACTOR; HEME PROTEINS; NONPOLAR AMINO ACIDS; PEROXIDASE; PEROXIDASE ACTIVITIES; PROTEIN DESIGN; PURIFIED PROTEIN; RANDOM MUTAGENESIS; SYNTHETIC BIOLOGY;

BINARY CODES; BINARY SEQUENCES; BIOLOGY; ENZYME ACTIVITY; PORPHYRINS;

PROTEINS;

HEMOPROTEIN; PEROXIDASE;

AMINO ACID SEQUENCE; ARTICLE; COLOR; CONTROLLED STUDY; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ENGINEERING; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; DIRECTED MOLECULAR EVOLUTION; ESCHERICHIA COLI; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE LIBRARY; PEROXIDASE; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; TRANSFORMATION, GENETIC;

EID: 84865772972     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzs025     Document Type: Article

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