Synthesis and anticancer activity of 5-(3-indolyl)-1,3,4-thiadiazoles

European Journal of Medicinal Chemistry

Volumn 45, Issue 10, 2010, Pages 4664-4668

  Kumar, Dalip ^a   Maruthi Kumar, N ^a   Chang, Kuei Hua ^b   Shah, Kavita ^b  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^b PURDUE UNIVERSITY   (United States)

Author keywords

1,3,4 Thiadiazole; Anticancer agents; Indolyl azoles; Indolyl heterocycles

Indexed keywords

2 (3,4 DIMETHOXYPHENYL) 5 1H INDOL 3 YL 1,3,4 THIADIAZOLE; 2 (4 CHLOROPHENYL) 5 1H INDOL 3 YL 1,3,4 THIADIAZOLE; 2 (4 DIMETHYLAMINOPHENYL) 5 1H INDOL 3 YL 1,3,4 THIADIAZOLE; 2 (5 BROMO 3 INDOLYL) 5 (3,4,5 TRIMETHOXYPHENYL) 1,3,4 THIADIAZOLE; 2 1H INDOL 3 YL 5 (3 PYRIDYL) 1,3,4 THIADIAZOLE; 2 1H INDOL 3 YL 5 (3,4,5 TRIMETHOXYPHENYL) 1,3,4 THIADIAZOLE; 2 1H INDOL 3 YL 5 (4 PYRIDYL) 1,3,4 THIADIAZOLE; 2 1H INDOL 3 YL 5 PHENYL 1,3,4 THIADIAZOLE; 2 [4 (BENZYLOXY) 3 METHOXYPHENYL] 5 1H INDOL 3 YL 1,3,4 THIADIAZOLE; 2 [4 (BENZYLOXY) 5 (5 BROMO 3 INDOLYL) 3 METHOXYPHENYL] 1,3,4 THIADIAZOLE; 2 BENZYL 5 1H INDOL 3 YL 1,3,4 THIADIAZOLE; 3 INDOLECARBOXYLIC ACID; 5 (5 BROMO 3 INDOLYL) 2 (4 DIMETHYLAMINOPHENYL) 1,3,4 THIADIAZOLE; 5 1H INDOL 3 YL 2 (3,4 METHYLENEDIOXYPHENYL) 1,3,4 THIADIAZOLE; CARBOXYLIC ACID DERIVATIVE; HYDRAZIDE; LAWESSON REAGENT; REAGENT; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; INDOLES; MALE; PANCREATIC NEOPLASMS; PROSTATIC NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES;

EID: 77956189883     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.07.023     Document Type: Article

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