Synthesis of 2-amino-5-sulfanyl-1,3,4-thiadiazole derivatives and evaluation of their antidepressant and anxiolytic activity

Journal of Medicinal Chemistry

Volumn 44, Issue 6, 2001, Pages 931-936

  Clerici, F ^a   Pocar, D ^a   Guido, M ^b,d   Loche, A ^b   Perlini, V ^b   Brufani, M ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b G E T Laboratori di ricerca   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Homeopharm ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 SULFANYL 1,3,4 THIADIAZOLE DERIVATIVE; 5 (3 METHOXYBENZYLSULFANYL) 1,3,4 THIADIAZOL 2 YLAMINE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; DIAZEPAM; IMIPRAMINE; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; ATAXIA; AVOIDANCE BEHAVIOR; DEPRESSION; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PSYCHOPHARMACOLOGY; RAT; SEDATION; SOCIAL INTERACTION; TRANQUILIZING ACTIVITY;

AMNESIA; ANIMALS; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; AVOIDANCE LEARNING; DRUG SYNERGISM; ETHANOL; MALE; MICE; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; SOCIAL BEHAVIOR; STRUCTURE-ACTIVITY RELATIONSHIP; SULFIDES; THIADIAZOLES;

EID: 0035866653     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001027w     Document Type: Article

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