Structure of a β-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-κB signaling

Glycoconjugate Journal

Volumn 29, Issue 5-6, 2012, Pages 365-377

  Fang, Jianping ^a   Wang, Ying ^a   Lv, Xiaofen ^a   Shen, Xiaokun ^a   Ni, Xinyan ^a   Ding, Kan ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

glucan.; Biological response modifier.; Dectin 1; Grifola frondosa.

Indexed keywords

BETA GLUCAN; CONCANAVALIN A; CYCLOPHOSPHAMIDE; DECTIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; PROTEIN KINASE SYK; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANION EXCHANGE CHROMATOGRAPHY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARBOHYDRATE ANALYSIS; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PHAGOCYTOSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOSE RESPONSE; DRUG DETERMINATION; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; FEMALE; GRIFOLA FRONDOSA; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; INTRACELLULAR SIGNALING; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN BINDING; SARCOMA; TUMOR REGRESSION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BETA-GLUCANS; CARBOHYDRATE SEQUENCE; CELL LINE, TUMOR; FRUITING BODIES, FUNGAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GRIFOLA; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED ICR; NF-KAPPA B; PHAGOCYTOSIS; POLYSACCHARIDES; PROTEIN-TYROSINE KINASES; SARCOMA; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

GRIFOLA FRONDOSA; MUS;

EID: 84865716564     PISSN: 02820080     EISSN: 15734986     Source Type: Journal    
DOI: 10.1007/s10719-012-9416-z     Document Type: Article

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