Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo

Journal of Allergy and Clinical Immunology

Volumn 130, Issue 3, 2012, Pages

  Gundavarapu, Sravanthi ^a   Wilder, Julie A ^a   Mishra, Neerad C ^a   Rir Sima Ah, Jules ^a   Langley, Raymond J ^a   Singh, Shashi P ^a   Saeed, Ali Imran ^b   Jaramillo, Richard J ^a   Gott, Katherine M ^a   Peña Philippides, Juan Carlos ^a   Harrod, Kevin S ^a   McIntosh, J Michael ^c   Buch, Shilpa ^d   Sopori, Mohan L ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

acetylcholine; airway mucus; Cigarette smoke; nicotine; nicotinic acetylcholine receptors; aminobutyric acid receptors

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ACETYLCHOLINE; CIGARETTE SMOKE; INTERLEUKIN 13; NICOTINE; NICOTINIC RECEPTOR; PICROTOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS MUCUS; CONTROLLED STUDY; EPITHELIUM CELL; GENE SILENCING; HUMAN; HUMAN CELL; HYPERPLASIA; IN VITRO STUDY; IN VIVO STUDY; METAPLASIA; MUCOUS CELL; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84865676735     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.04.002     Document Type: Article

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