메뉴 건너뛰기




Volumn 183, Issue 3, 2009, Pages 2115-2121

Maternal exposure to secondhand cigarette smoke primes the lung for induction of phosphodiesterase-4D5 isozyme and exacerbated Th2 responses: Rolipram attenuates the airway hyperreactivity and muscarinic receptor expression but not lung inflammation and atopy

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC RECEPTOR; PHOSPHODIESTERASE IV; ROLIPRAM; CYTOKINE; ISOENZYME;

EID: 68149180520     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900826     Document Type: Article
Times cited : (51)

References (61)
  • 1
    • 0036580648 scopus 로고    scopus 로고
    • Effects of cigarette smoke on the immune system
    • Sopori, M. 2002. Effects of cigarette smoke on the immune system. Nat. Rev. Immunol. 2: 372-377. (Pubitemid 37328760)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.5 , pp. 372-377
    • Sopori, M.1
  • 2
    • 1842534366 scopus 로고    scopus 로고
    • Prenatal and Postnatal Environmental Tobacco Smoke Exposure and Children's Health
    • DiFranza, J. F., A. Aligne, and M. Weitzman. 2004. Prenatal and postnatal environmental tobacco smoke exposure and children's health. Pediatrics 113: 1007-1015. (Pubitemid 38437353)
    • (2004) Pediatrics , vol.113 , Issue.4 II , pp. 1007-1015
    • DiFranza, J.R.1    Aligne, C.A.2    Weitzman, M.3
  • 7
    • 0023270537 scopus 로고
    • Maternal smoking during pregnancy and lower respiratory tract illness in early life
    • Taylor, B., and J. Wadsworth. 1987. Maternal smoking during pregnancy and lower respiratory tract illness in early life. Arch. Dis. Child. 62: 786-791. (Pubitemid 17128825)
    • (1987) Archives of Disease in Childhood , vol.62 , Issue.8 , pp. 786-791
    • Taylor, B.1    Wadsworth, J.2
  • 8
    • 3042600119 scopus 로고    scopus 로고
    • Prenatal nicotine exposure increases connective tissue expression in foetal monkey pulmonary vessels
    • Sekhon, H. S., B. J. Proskocil, J. A. Clark, and E. R. Spindel. 2004. Prenatal nicotine exposure increases connective tissue expression in foetal monkey pulmonary vessels. Eur. Respir. J. 23: 906-915.
    • (2004) Eur. Respir. J. , vol.23 , pp. 906-915
    • Sekhon, H.S.1    Proskocil, B.J.2    Clark, J.A.3    Spindel, E.R.4
  • 10
    • 0028303924 scopus 로고
    • Maternal smoking during pregnancy as a predictor of lung function in children
    • Cunningham, J., D. W. Dockery, and F. E. Speizer. 1994. Maternal smoking during pregnancy as a predictor of lung function in children. Am. J. Epidemiol. 139: 1139-1152. (Pubitemid 24184408)
    • (1994) American Journal of Epidemiology , vol.139 , Issue.12 , pp. 1139-1152
    • Cunningham, J.1    Dockery, D.W.2    Speizer, F.E.3
  • 11
    • 0035964559 scopus 로고    scopus 로고
    • Smoking during pregnancy in the 1990s
    • Mathews, T. J. 2001. Smoking during pregnancy in the 1990s. Natl. Vital Stat. Rep. 49: 1-14.
    • (2001) Natl. Vital Stat. Rep. , vol.49 , pp. 1-14
    • Mathews, T.J.1
  • 14
    • 0017707071 scopus 로고
    • Extrinsic allergic alveolitis: A disease commoner in non-smokers
    • Warren, C. P. 1977. Extrinsic allergic alveolitis: a disease commoner in nonsmokers. Thorax 32: 567-569. (Pubitemid 8205842)
    • (1977) Thorax , vol.32 , Issue.5 , pp. 567-569
    • Warren, C.P.W.1
  • 15
    • 0024803939 scopus 로고
    • A meta-analysis of the role of smoking in inflammatory bowel disease
    • Calkins, B. M. 1989. A meta-analysis of the role of smoking in inflammatory bowel disease. Dig. Dis. Sci. 34: 1841-1854.
    • (1989) Dig. Dis. Sci. , vol.34 , pp. 1841-1854
    • Calkins, B.M.1
  • 16
    • 0030065436 scopus 로고    scopus 로고
    • Beneficial effects of nicotine and cigarette smoking: The real, the possible, and the spurious
    • Baron, J. A. 1996. Beneficial effects of nicotine and cigarette smoking: the real, the possible, and the spurious. Br. Med. Bull. 52: 58-73.
    • (1996) Br. Med. Bull. , vol.52 , pp. 58-73
    • Baron, J.A.1
  • 17
    • 0028711158 scopus 로고
    • Smoking: Adverse effects on outcome for plastic surgical patients
    • Netscher, D. T., and J. Clamon. 1994. Smoking: adverse effects on outcome for plastic surgical patients. Plast. Surg. Nurs. 14: 205-210.
    • (1994) Plast. Surg. Nurs. , vol.14 , pp. 205-210
    • Netscher, D.T.1    Clamon, J.2
  • 19
    • 8944255151 scopus 로고    scopus 로고
    • Skin prick test reactivity to common aeroallergens in relation to total IgE, respiratory symptoms, and smoking in a general population sample of northern Italy
    • Baldacci, S., P. Modena, L. Carrozi, M. Pedreschi, M. Vellutini, P. Biavati, M. Simoni, T. Sapigni, G. Viegi, P. Paoletti, and C. Giuntini. 1996. Skin prick test reactivity to common aeroallergens in relation to total IgE, respiratory symptoms, and smoking in a general population sample of northern Italy. Allergy 51: 149-156.
    • (1996) Allergy , vol.51 , pp. 149-156
    • Baldacci, S.1    Modena, P.2    Carrozi, L.3    Pedreschi, M.4    Vellutini, M.5    Biavati, P.6    Simoni, M.7    Sapigni, T.8    Viegi, G.9    Paoletti, P.10    Giuntini, C.11
  • 20
    • 0028892556 scopus 로고
    • Cigarette smoking and incidence of chronic bronchitis and asthma in women
    • Troisi, R. J., F. E. Speizer, B. Rosner, D. Trichopoulos, and W. C. Willett. 1995. Cigarette smoking and incidence of chronic bronchitis and asthma in women. Chest 108: 1557-1561.
    • (1995) Chest , vol.108 , pp. 1557-1561
    • Troisi, R.J.1    Speizer, F.E.2    Rosner, B.3    Trichopoulos, D.4    Willett, W.C.5
  • 27
    • 0026663744 scopus 로고
    • A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE
    • Kurup, V. P., S. Mauze, H. Choi, B. W. Seymour, and R. L. Coffman. 1992. A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE. J. Immunol. 148: 3783-3788.
    • (1992) J. Immunol. , vol.148 , pp. 3783-3788
    • Kurup, V.P.1    Mauze, S.2    Choi, H.3    Seymour, B.W.4    Coffman, R.L.5
  • 28
    • 0037092564 scopus 로고    scopus 로고
    • Cigarette smoke-induced airway hyperresponsiveness is not dependent on elevated immunoglobulin and eosinophilic inflammation in a mouse model of allergic airway disease
    • Barrett, E. G., J. Wilder, T. H. March, T. Espindola, and D. E. Bice. 2002. Cigarette smoke-induced airway hyperresponsiveness is not dependent on elevated immunoglobulin and eosinophilic inflammation in a mouse model of allergic airway disease. Am. J. Respir. Crit. Care Med. 165: 1410-1418.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.165 , pp. 1410-1418
    • Barrett, E.G.1    Wilder, J.2    March, T.H.3    Espindola, T.4    Bice, D.E.5
  • 29
    • 22844432825 scopus 로고    scopus 로고
    • Aspergillus antigens: Which are important?
    • Kurup, V. P. 2005. Aspergillus antigens: which are important? Med. Mycol. 43(Suppl. 1): S189-S196.
    • (2005) Med. Mycol. , vol.43 , Issue.SUPPL. 1
    • Kurup, V.P.1
  • 30
    • 0023270906 scopus 로고
    • Aspergillus fumigatus-specific antibodies in allergic bronchopulmonary aspergillosis and aspergilloma: Evidence for a polyclonal antibody response
    • Brummund, W., A. Resnick, J. N. Fink, and V. P. Kurup. 1987. Aspergillus fumigatus-specific antibodies in allergic bronchopulmonary aspergillosis and aspergilloma: evidence for a polyclonal antibody response. J. Clin. Microbiol. 25: 5-9.
    • (1987) J. Clin. Microbiol. , vol.25 , pp. 5-9
    • Brummund, W.1    Resnick, A.2    Fink, J.N.3    Kurup, V.P.4
  • 31
    • 34247525096 scopus 로고    scopus 로고
    • Expression of cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormone-stimulated activities in immature rat sertoli cells
    • Levallet, G., J. Levallet, H. Bouraima-Lelong, and P. J. Bonnamy. 2007. Expression of cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormone-stimulated activities in immature rat sertoli cells. Biol. Reprod. 76: 794-803.
    • (2007) Biol. Reprod. , vol.76 , pp. 794-803
    • Levallet, G.1    Levallet, J.2    Bouraima-Lelong, H.3    Bonnamy, P.J.4
  • 33
    • 0036785044 scopus 로고    scopus 로고
    • A reevaluation of the validity of unrestrained plethysmography in mice
    • Lundblad, L. K., C. G. Irvin, A. Adler, and J. H. Bates. 2002. A reevaluation of the validity of unrestrained plethysmography in mice. J. Appl. Physiol. 93: 1198-1207.
    • (2002) J. Appl. Physiol. , vol.93 , pp. 1198-1207
    • Lundblad, L.K.1    Irvin, C.G.2    Adler, A.3    Bates, J.H.4
  • 34
    • 50849122094 scopus 로고    scopus 로고
    • Neutrophilic airway inflammation and association with bacterial lipopolysaccharide in children with asthma and wheezing
    • Hauk, P. J., M. Krawiec, J. Murphy, J. Boguniewicz, A. Schiltz, E. Goleva, A. H. Liu, and D. Y. Leung. 2008. Neutrophilic airway inflammation and association with bacterial lipopolysaccharide in children with asthma and wheezing. Pediatr. Pulmonol. 43: 916-923.
    • (2008) Pediatr. Pulmonol. , vol.43 , pp. 916-923
    • Hauk, P.J.1    Krawiec, M.2    Murphy, J.3    Boguniewicz, J.4    Schiltz, A.5    Goleva, E.6    Liu, A.H.7    Leung, D.Y.8
  • 35
    • 0033870189 scopus 로고    scopus 로고
    • Immunopathology of allergy and asthma in childhood
    • Jones, C. A., and P. G. Holt. 2000. Immunopathology of allergy and asthma in childhood. Am. J. Respir. Crit. Care Med. 162: S36-S39.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.162
    • Jones, C.A.1    Holt, P.G.2
  • 36
    • 34748842665 scopus 로고    scopus 로고
    • Triggers of IgE class switching and allergy development
    • Poulsen, L. K., and L. Hummelshoj. 2007. Triggers of IgE class switching and allergy development. Ann. Med. 39: 440-456.
    • (2007) Ann. Med. , vol.39 , pp. 440-456
    • Poulsen, L.K.1    Hummelshoj, L.2
  • 37
    • 0036104682 scopus 로고    scopus 로고
    • Animal models of allergic bronchopulmonary aspergillosis
    • Kurup, V. P., and G. Grunig. 2002. Animal models of allergic bronchopulmonary aspergillosis. Mycopathologia 153: 165-177.
    • (2002) Mycopathologia , vol.153 , pp. 165-177
    • Kurup, V.P.1    Grunig, G.2
  • 38
    • 33745218112 scopus 로고    scopus 로고
    • Muscarinic receptor signaling in the pathophysiology of asthma and COPD
    • Gosens, R., J. Zaagsma, H. Meurs, and A. J. Halayko. 2006. Muscarinic receptor signaling in the pathophysiology of asthma and COPD. Respir. Res. 7: 73-88.
    • (2006) Respir. Res. , vol.7 , pp. 73-88
    • Gosens, R.1    Zaagsma, J.2    Meurs, H.3    Halayko, A.J.4
  • 40
    • 0032600823 scopus 로고    scopus 로고
    • The role of cigarette smoke in the pathogenesis of asthma and as a trigger for acute symptoms
    • Floreani, A. A., and S. I. Rennard. 1999. The role of cigarette smoke in the pathogenesis of asthma and as a trigger for acute symptoms. Curr. Opin. Pulm. Med. 5: 38-46.
    • (1999) Curr. Opin. Pulm. Med. , vol.5 , pp. 38-46
    • Floreani, A.A.1    Rennard, S.I.2
  • 41
    • 24744452430 scopus 로고    scopus 로고
    • Second-hand smoke increases nitric oxide and alters the IgE response in a murine model of allergic aspergillosis
    • Seymour, B. W., J. L. Peake, K. E. Pinkerton, V. P. Kurup, and L. J. Gershwin. 2005. Second-hand smoke increases nitric oxide and alters the IgE response in a murine model of allergic aspergillosis. Clin. Dev. Immunol. 12: 113-124.
    • (2005) Clin. Dev. Immunol. , vol.12 , pp. 113-124
    • Seymour, B.W.1    Peake, J.L.2    Pinkerton, K.E.3    Kurup, V.P.4    Gershwin, L.J.5
  • 42
    • 77957185270 scopus 로고
    • Effect of chronic cigarette smoke exposure on lung clearance of tracer particles inhaled by rats
    • Finch, G. L., K. J. Nikula, B. T. Chen, E. B. Barr, I. Y. Chang, and C. H. Hobbs. 1995. Effect of chronic cigarette smoke exposure on lung clearance of tracer particles inhaled by rats. Fundam. Appl. Toxicol. 24: 76-85.
    • (1995) Fundam. Appl. Toxicol. , vol.24 , pp. 76-85
    • Finch, G.L.1    Nikula, K.J.2    Chen, B.T.3    Barr, E.B.4    Chang, I.Y.5    Hobbs, C.H.6
  • 43
    • 52949103280 scopus 로고    scopus 로고
    • Can the anti-inflammatory potential of PDE4 inhibitors be realized: Guarded optimism or wishful thinking?
    • Giembycz, M. A. 2008. Can the anti-inflammatory potential of PDE4 inhibitors be realized: guarded optimism or wishful thinking? Br. J. Pharmacol. 155: 288-290.
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 288-290
    • Giembycz, M.A.1
  • 44
    • 52949140176 scopus 로고    scopus 로고
    • PDE4 inhibitors: Current status
    • Spina, D. 2008. PDE4 inhibitors: current status. Br. J. Pharmacol. 155: 308-315.
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 308-315
    • Spina, D.1
  • 45
    • 0142230947 scopus 로고    scopus 로고
    • Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19- 8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD)
    • Grootendorst, D. C., S. A. Gauw, N. Benschop, P. J. Sterk, P. S. Hiemstra, and K. F. Rabe. 2003. Efficacy of the novel phosphodiesterase-4 inhibitor BAY 19- 8004 on lung function and airway inflammation in asthma and chronic obstructive pulmonary disease (COPD). Pulm. Pharmacol. Ther. 16: 341-347.
    • (2003) Pulm. Pharmacol. Ther. , vol.16 , pp. 341-347
    • Grootendorst, D.C.1    Gauw, S.A.2    Benschop, N.3    Sterk, P.J.4    Hiemstra, P.S.5    Rabe, K.F.6
  • 46
    • 44449126768 scopus 로고    scopus 로고
    • Roflumilast: An oral, once-daily selective PDE-4 inhibitor for the management of COPD and asthma
    • Field, S. K. 2008. Roflumilast: an oral, once-daily selective PDE-4 inhibitor for the management of COPD and asthma. Expert Opin. Investig. Drugs 17: 811-818.
    • (2008) Expert Opin. Investig. Drugs , vol.17 , pp. 811-818
    • Field, S.K.1
  • 47
    • 0034612334 scopus 로고    scopus 로고
    • Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D
    • Hansen, G., S. Jin, D. T. Umetsu, and M. Conti. 2000. Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D. Proc. Natl. Acad. Sci. USA 97: 6751-6756.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6751-6756
    • Hansen, G.1    Jin, S.2    Umetsu, D.T.3    Conti, M.4
  • 48
    • 33748620914 scopus 로고    scopus 로고
    • Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma
    • Deng, Y. M., Q. M. Xie, H. F. Tang, J. G. Sun, J. F. Deng, J. Q. Chen, and S. Y. Yang. 2006. Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma. Eur. J. Pharmacol. 547: 125-135.
    • (2006) Eur. J. Pharmacol. , vol.547 , pp. 125-135
    • Deng, Y.M.1    Xie, Q.M.2    Tang, H.F.3    Sun, J.G.4    Deng, J.F.5    Chen, J.Q.6    Yang, S.Y.7
  • 49
    • 33745911590 scopus 로고    scopus 로고
    • Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors
    • Wollin, L., D. S. Bundschuh, A. Wohlsen, D. Marx, and R. Beume. 2006. Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors. Pulm. Pharmacol. Ther. 19: 343-352.
    • (2006) Pulm. Pharmacol. Ther. , vol.19 , pp. 343-352
    • Wollin, L.1    Bundschuh, D.S.2    Wohlsen, A.3    Marx, D.4    Beume, R.5
  • 50
    • 14744285888 scopus 로고    scopus 로고
    • Histone acetylation and deacetylation: Importance in inflammatory lung diseases
    • Barnes, P. J., I. M. Adcock, and K. Ito. 2005. Histone acetylation and deacetylation: importance in inflammatory lung diseases. Eur. Respir. J. 25: 552-563.
    • (2005) Eur. Respir. J. , vol.25 , pp. 552-563
    • Barnes, P.J.1    Adcock, I.M.2    Ito, K.3
  • 51
    • 33745099273 scopus 로고    scopus 로고
    • Histone deacetylation: An important mechanism in inflammatory lung diseases
    • Adcock, I. M., K. Ito, and P. J. Barnes. 2005. Histone deacetylation: an important mechanism in inflammatory lung diseases. COPD 2: 445-455.
    • (2005) COPD , vol.2 , pp. 445-455
    • Adcock, I.M.1    Ito, K.2    Barnes, P.J.3
  • 52
    • 36749030752 scopus 로고    scopus 로고
    • cAMP-specific phosphodiesterase-4D5 (PDE4D5) provides a paradigm for understanding the unique nonredundant roles that PDE4 isoforms play in shaping compartmentalized cAMP cell signalling
    • Lynch, M. J., G. S. Baillie, and M. D. Houslay. 2007. cAMP-specific phosphodiesterase-4D5 (PDE4D5) provides a paradigm for understanding the unique nonredundant roles that PDE4 isoforms play in shaping compartmentalized cAMP cell signalling. Biochem. Soc. Trans. 35: 938-941.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 938-941
    • Lynch, M.J.1    Baillie, G.S.2    Houslay, M.D.3
  • 53
    • 27344449614 scopus 로고    scopus 로고
    • Keynote review: Phosphodiesterase-4 as a therapeutic target
    • Houslay, M. D., P. Schafer, and K. Y. Zhang. 2005. Keynote review: phosphodiesterase-4 as a therapeutic target. Drug Discov. Today 10: 1503-1519.
    • (2005) Drug Discov. Today , vol.10 , pp. 1503-1519
    • Houslay, M.D.1    Schafer, P.2    Zhang, K.Y.3
  • 54
    • 0141445980 scopus 로고    scopus 로고
    • PDE4D plays a critical role in the control of airway smooth muscle contraction
    • Mehats, C., S.-L. C. Jin, J. Wahlstrom, E. Law, D. L. Umetsu, and M. Conti. 2003. PDE4D plays a critical role in the control of airway smooth muscle contraction. FASEB J. 17: 1831-1841.
    • (2003) FASEB J. , vol.17 , pp. 1831-1841
    • Mehats, C.1    Jin, S.-L.C.2    Wahlstrom, J.3    Law, E.4    Umetsu, D.L.5    Conti, M.6
  • 55
    • 0031774720 scopus 로고    scopus 로고
    • International Union of Pharmacology. XVII. Classification of muscaranic acetylcholine receptors
    • Caulfield, M. P., and N. J. M. Birdsall. 1998. International Union of Pharmacology. XVII. Classification of muscaranic acetylcholine receptors. Pharmacol. Rev. 50: 279-290.
    • (1998) Pharmacol. Rev. , vol.50 , pp. 279-290
    • Caulfield, M.P.1    Birdsall, N.J.M.2
  • 56
    • 0032561331 scopus 로고    scopus 로고
    • Muscaranic receptor subtype in the porcine lung during postnatal development
    • Hislop, A. A., J. C. Mak, J. A. Reader, P. J. Barnes, and S. G. Haworth. 1998. Muscaranic receptor subtype in the porcine lung during postnatal development. Eur. J. Pharmacol. 359: 211-221.
    • (1998) Eur. J. Pharmacol. , vol.359 , pp. 211-221
    • Hislop, A.A.1    Mak, J.C.2    Reader, J.A.3    Barnes, P.J.4    Haworth, S.G.5
  • 57
    • 0029897315 scopus 로고    scopus 로고
    • Neuromodulation of transduction and signal processing in the end organs of taste
    • Nagai, T., D. J. Kim, R. J. Delay, and S. D. Roper. 1996. Neuromodulation of transduction and signal processing in the end organs of taste. Chem. Senses 21: 353-365.
    • (1996) Chem. Senses , vol.21 , pp. 353-365
    • Nagai, T.1    Kim, D.J.2    Delay, R.J.3    Roper, S.D.4
  • 58
    • 33748117796 scopus 로고    scopus 로고
    • Interleukin-6: Discovery of a pleiotropic cytokine
    • Kishimoto, T. 2006. Interleukin-6: discovery of a pleiotropic cytokine. Arthritis Res. Ther. 8(Suppl. 2): S2.
    • (2006) Arthritis Res. Ther. , vol.8 , Issue.SUPPL. 2
    • Kishimoto, T.1
  • 60
    • 0035719959 scopus 로고    scopus 로고
    • Eotaxin and the attraction of eosinophils to the asthmatic lung
    • Conroy, D. M., and T. J. Williams. 2001. Eotaxin and the attraction of eosinophils to the asthmatic lung. Respir. Res. 2: 150-156.
    • (2001) Respir. Res. , vol.2 , pp. 150-156
    • Conroy, D.M.1    Williams, T.J.2
  • 61
    • 56749183895 scopus 로고    scopus 로고
    • Epigenetic mechanisms in health and disease
    • Van der Maarel, S. M. 2008. Epigenetic mechanisms in health and disease. Ann. Rheum. Dis. 67(Suppl. 3): iii97-100.
    • (2008) Ann. Rheum. Dis. , vol.67 , Issue.SUPPL. 3
    • Van Der Maarel, S.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.