Mammary fibroblasts regulate morphogenesis of normal and tumorigenic breast epithelial cells by mechanical and paracrine signals

Cancer Letters

Volumn 325, Issue 2, 2012, Pages 175-188

  Lühr, Inke ^a   Friedl, Andreas ^b   Overath, Thorsten ^a   Tholey, Andreas ^a   Kunze, Thomas ^a   Hilpert, Felix ^a   Sebens, Susanne ^c   Arnold, Norbert ^a   Rösel, Frank ^a   Oberg, Hans Heinrich ^a   Maass, Nicolai ^d   Mundhenke, Christoph ^a   Jonat, Walter ^a   Bauer, Maret ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Acinar morphogenesis; Breast cancer; Mammary fibroblasts; Matrix compliance; Microenvironment

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; VIMENTIN;

ARTICLE; BREAST CARCINOMA; BREAST EPITHELIUM; BREAST FIBROBLAST; CANCER ASSOCIATED FIBROBLAST; CARCINOGENICITY; CARCINOMA CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CLINICAL ARTICLE; COCULTURE; CONTROLLED STUDY; EPITHELIUM CELL; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; MECHANOTRANSDUCTION; MORPHOGENESIS; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA CELL; TUMOR GROWTH;

BREAST; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL DIVISION; CELL SHAPE; CELLS, CULTURED; COCULTURE TECHNIQUES; COMPLIANCE; EPITHELIAL CELLS; EXTRACELLULAR MATRIX; FEMALE; FIBROBLASTS; HUMANS; MORPHOGENESIS; PARACRINE COMMUNICATION; PHENOTYPE; STRESS, MECHANICAL; STROMAL CELLS; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT;

EID: 84865624154     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.06.014     Document Type: Article

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