-
1
-
-
75149115045
-
Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: A summary report from the Honolulu-Asia aging study
-
White L. Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: a summary report from the Honolulu-Asia aging study. J Alzheimers Dis. 2009;18(3):713-725.
-
(2009)
J Alzheimers Dis.
, vol.18
, Issue.3
, pp. 713-725
-
-
White, L.1
-
2
-
-
70149097327
-
The neuropathology of probable Alzheimer disease and mild cognitive impairment
-
Schneider JA, Arvanitakis Z, Leurgans SE, Bennett DA. The neuropathology of probable Alzheimer disease and mild cognitive impairment. Ann Neurol. 2009;66(2):200-208.
-
(2009)
Ann Neurol.
, vol.66
, Issue.2
, pp. 200-208
-
-
Schneider, J.A.1
Arvanitakis, Z.2
Leurgans, S.E.3
Bennett, D.A.4
-
3
-
-
79956142378
-
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7(3):263-269.
-
(2011)
Alzheimers Dement
, vol.7
, Issue.3
, pp. 263-269
-
-
McKhann, G.M.1
Knopman, D.S.2
Chertkow, H.3
-
4
-
-
79956084514
-
The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7(3):270-279.
-
(2011)
Alzheimers Dement.
, vol.7
, Issue.3
, pp. 270-279
-
-
Albert, M.S.1
DeKosky, S.T.2
Dickson, D.3
-
5
-
-
79956098248
-
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Sperling RA, Aisen PS, Beckett LA, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7(3):280-292.
-
(2011)
Alzheimers Dement.
, vol.7
, Issue.3
, pp. 280-292
-
-
Sperling, R.A.1
Aisen, P.S.2
Beckett, L.A.3
-
6
-
-
77957951112
-
Revising the definition of Alzheimer's disease: A new lexicon
-
Dubois B, Feldman HH, Jacova C, et al. Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol. 2010;9(11):1118-1127.
-
(2010)
Lancet Neurol.
, vol.9
, Issue.11
, pp. 1118-1127
-
-
Dubois, B.1
Feldman, H.H.2
Jacova, C.3
-
7
-
-
80051553765
-
The dynamics of cortical and hippocampal atrophy in Alzheimer disease
-
Alzheimer's Disease Neuroimaging Initiative
-
Sabuncu MR, Desikan RS, Sepulcre J, et al Alzheimer's Disease Neuroimaging Initiative. The dynamics of cortical and hippocampal atrophy in Alzheimer disease. Arch Neurol. 2011;68(8):1040-1048.
-
(2011)
Arch Neurol
, vol.68
, Issue.8
, pp. 1040-1048
-
-
Sabuncu, M.R.1
Desikan, R.S.2
Sepulcre, J.3
-
8
-
-
66249125569
-
A meta-analysis of hippocampal atrophy rates in Alzheimer's disease
-
Barnes J, Bartlett JW, van de Pol LA, et al. A meta-analysis of hippocampal atrophy rates in Alzheimer's disease. Neurobiol Aging. 2009;30(11):1711-1723.
-
(2009)
Neurobiol Aging
, vol.30
, Issue.11
, pp. 1711-1723
-
-
Barnes, J.1
Bartlett, J.W.2
Van De Pol, L.A.3
-
9
-
-
79952712480
-
Hippocampal morphometry in population-based incident Alzheimer's disease and vascular dementia: The HAAS
-
Scher AI, Xu Y, Korf ES, et al. Hippocampal morphometry in population-based incident Alzheimer's disease and vascular dementia: the HAAS. J Neurol Neurosurg Psychiatry. 2011;82(4):373-376.
-
(2011)
J Neurol Neurosurg Psychiatry.
, vol.82
, Issue.4
, pp. 373-376
-
-
Scher, A.I.1
Xu, Y.2
Korf, E.S.3
-
10
-
-
79960942624
-
Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia
-
Ewers M, Sperling RA, Klunk WE, Weiner MW, Hampel H. Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia. Trends Neurosci. 2011;34(8):430-442.
-
(2011)
Trends Neurosci.
, vol.34
, Issue.8
, pp. 430-442
-
-
Ewers, M.1
Sperling, R.A.2
Klunk, W.E.3
Weiner, M.W.4
Hampel, H.5
-
11
-
-
77954706306
-
Serial MRI and CSF biomarkers in normal aging, MCI, and AD
-
Alzheimer's Disease Neuroimaging Initiative
-
Vemuri P, Wiste HJ, Weigand SD, et al Alzheimer's Disease Neuroimaging Initiative. Serial MRI and CSF biomarkers in normal aging, MCI, and AD. Neurology. 2010;75(2):143-151.
-
(2010)
Neurology
, vol.75
, Issue.2
, pp. 143-151
-
-
Vemuri, P.1
Wiste, H.J.2
Weigand, S.D.3
-
12
-
-
79953041925
-
Characterizing Alzheimer's disease using a hypometabolic convergence index
-
Alzheimer's Disease Neuroimaging Initiative
-
Chen K, Ayutyanont N, Langbaum JB, et al Alzheimer's Disease Neuroimaging Initiative. Characterizing Alzheimer's disease using a hypometabolic convergence index. Neuroimage. 2011;56(1):52-60.
-
(2011)
Neuroimage
, vol.56
, Issue.1
, pp. 52-60
-
-
Chen, K.1
Ayutyanont, N.2
Langbaum, J.B.3
-
13
-
-
79952578268
-
Temporoparietal hypometabolism in frontotemporal lobar degeneration and associated imaging diagnostic errors
-
Womack KB, Diaz-Arrastia R, Aizenstein HJ, et al. Temporoparietal hypometabolism in frontotemporal lobar degeneration and associated imaging diagnostic errors. Arch Neurol. 2011;68(3):329-337.
-
(2011)
Arch Neurol.
, vol.68
, Issue.3
, pp. 329-337
-
-
Womack, K.B.1
Diaz-Arrastia, R.2
Aizenstein, H.J.3
-
14
-
-
79951520786
-
In vivo fibrillar beta-amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults
-
Sojkova J, Driscoll I, Iacono D, et al. In vivo fibrillar beta-amyloid detected using [11C]PiB positron emission tomography and neuropathologic assessment in older adults. Arch Neurol. 2011;68(2):232-240.
-
(2011)
Arch Neurol
, vol.68
, Issue.2
, pp. 232-240
-
-
Sojkova, J.1
Driscoll, I.2
Iacono, D.3
-
15
-
-
55949117032
-
Frequent amyloid deposition without significant cognitive impairment among the elderly
-
Aizenstein HJ, Nebes RD, Saxton JA, et al. Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol. 2008;65(11):1509-1517.
-
(2008)
Arch Neurol.
, vol.65
, Issue.11
, pp. 1509-1517
-
-
Aizenstein, H.J.1
Nebes, R.D.2
Saxton, J.A.3
-
16
-
-
77949300796
-
11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: A phase 2, double-blind, placebo-controlled, ascending-dose study
-
Rinne JO, Brooks DJ, Rossor MN, et al. 11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study. Lancet Neurol. 2010;9(4):363-372.
-
(2010)
Lancet Neurol.
, vol.9
, Issue.4
, pp. 363-372
-
-
Rinne, J.O.1
Brooks, D.J.2
Rossor, M.N.3
-
17
-
-
33644832047
-
42 in humans
-
DOI 10.1002/ana.20730
-
Fagan AM, Mintun MA, Mach RH, et al. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans. Ann Neurol. 2006;59(3):512-519. (Pubitemid 43358072)
-
(2006)
Annals of Neurology
, vol.59
, Issue.3
, pp. 512-519
-
-
Fagan, A.M.1
Mintun, M.A.2
Mach, R.H.3
Lee, S.-Y.4
Dence, C.S.5
Shah, A.R.6
LaRossa, G.N.7
Spinner, M.L.8
Klunk, W.E.9
Mathis, C.A.10
DeKosky, S.T.11
Morris, J.C.12
Holtzman, D.M.13
-
18
-
-
77949423619
-
Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
-
Blennow K, Hampel H, Weiner M, Zetterberg H. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat Rev Neurol. 2010;6(3):131-144.
-
(2010)
Nat Rev Neurol
, vol.6
, Issue.3
, pp. 131-144
-
-
Blennow, K.1
Hampel, H.2
Weiner, M.3
Zetterberg, H.4
-
19
-
-
35948933394
-
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
-
DOI 10.1038/nm1653, PII NM1653
-
Ray S, Britschgi M, Herbert C, et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med. 2007;13(11):1359-1362. (Pubitemid 350073592)
-
(2007)
Nature Medicine
, vol.13
, Issue.11
, pp. 1359-1362
-
-
Ray, S.1
Britschgi, M.2
Herbert, C.3
Takeda-Uchimura, Y.4
Boxer, A.5
Blennow, K.6
Friedman, L.F.7
Galasko, D.R.8
Jutel, M.9
Karydas, A.10
Kaye, J.A.11
Leszek, J.12
Miller, B.L.13
Minthon, L.14
Quinn, J.F.15
Rabinovici, G.D.16
Robinson, W.H.17
Sabbagh, M.N.18
So, Y.T.19
Sparks, D.L.20
Tabaton, M.21
Tinklenberg, J.22
Yesavage, J.A.23
Tibshirani, R.24
Wyss-Coray, T.25
more..
-
20
-
-
73349091534
-
A phase 2 multiple ascending dose trial of bapineuzumab inmild to moderate Alzheimer disease
-
Bapineuzumab 201 Clinical Trial Investigators
-
Salloway S, Sperling R, Gilman S, et al Bapineuzumab 201 Clinical Trial Investigators. A phase 2 multiple ascending dose trial of bapineuzumab inmild to moderate Alzheimer disease. Neurology. 2009;73(24):2061-2070.
-
(2009)
Neurology
, vol.73
, Issue.24
, pp. 2061-2070
-
-
Salloway, S.1
Sperling, R.2
Gilman, S.3
-
21
-
-
20344381835
-
Vitamin E and donepezil for the treatment of mild cognitive impairment
-
DOI 10.1056/NEJMoa050151
-
Petersen RC, Thomas RG, Grundman M, et al Alzheimer's Disease Cooperative Study Group. Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005;352(23):2379-2388. (Pubitemid 40958434)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.23
, pp. 2379-2388
-
-
Petersen, R.C.1
Thomas, R.G.2
Grundman, M.3
Bennett, D.4
Doody, R.5
Ferris, S.6
Galasko, D.7
Jin, S.8
Kaye, J.9
Levey, A.10
Pfeiffer, E.11
Sano, M.12
Van Dyck, C.H.13
Thal, L.J.14
-
22
-
-
33745266146
-
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
-
DOI 10.1038/sj.tpj.6500369, PII 6500369
-
Risner ME, Saunders AM, Altman JF, et al Rosiglitazone in Alzheimer's Disease Study Group. Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease. Pharmacogenomics J. 2006;6(4):246-254. (Pubitemid 44137951)
-
(2006)
Pharmacogenomics Journal
, vol.6
, Issue.4
, pp. 246-254
-
-
Risner, M.E.1
Saunders, A.M.2
Altman, J.F.B.3
Ormandy, G.C.4
Craft, S.5
Foley, I.M.6
Zvartau-Hind, M.E.7
Hosford, D.A.8
Roses, A.D.9
-
23
-
-
79960817113
-
Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer's Association Research Roundtable Workgroup
-
Sperling RA, Jack CR Jr, Black SE, et al. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup. Alzheimers Dement. 2011;7(4):367-385.
-
(2011)
Alzheimers Dement.
, vol.7
, Issue.4
, pp. 367-385
-
-
Sperling, R.A.1
Jack Jr., C.R.2
Black, S.E.3
-
24
-
-
84862777153
-
Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: A retrospective analysis
-
Sperling R, Salloway S, Brooks DJ, et al. Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. Lancet Neurol. 2012;11(3):241-249.
-
(2012)
Lancet Neurol.
, vol.11
, Issue.3
, pp. 241-249
-
-
Sperling, R.1
Salloway, S.2
Brooks, D.J.3
-
25
-
-
78651297619
-
Meta-analysis of the association between variants in SORL1 and Alzheimer disease
-
Genetic and Environmental Risk in Alzheimer Disease 1 Consortium
-
Reitz C, Cheng R, Rogaeva E, et al; Genetic and Environmental Risk in Alzheimer Disease 1 Consortium. Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Arch Neurol. 2011;68(1):99-106.
-
(2011)
Arch Neurol
, vol.68
, Issue.1
, pp. 99-106
-
-
Reitz, C.1
Cheng, R.2
Rogaeva, E.3
-
26
-
-
79955464911
-
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
-
Naj AC, Jun G, Beecham GW, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011;43(5):436-441.
-
(2011)
Nat Genet.
, vol.43
, Issue.5
, pp. 436-441
-
-
Naj, A.C.1
Jun, G.2
Beecham, G.W.3
-
27
-
-
77957909886
-
Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes
-
Alzheimer's Disease Genetics Consortium
-
Jun G, Naj AC, Beecham GW, et al Alzheimer's Disease Genetics Consortium. Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol. 2010;67(12):1473-1484.
-
(2010)
Arch Neurol
, vol.67
, Issue.12
, pp. 1473-1484
-
-
Jun, G.1
Naj, A.C.2
Beecham, G.W.3
-
29
-
-
81855185515
-
Phenotypic signatures of genetic frontotemporal dementia
-
Rohrer JD, Warren JD. Phenotypic signatures of genetic frontotemporal dementia. Curr Opin Neurol. 2011;24(6):542-549.
-
(2011)
Curr Opin Neurol.
, vol.24
, Issue.6
, pp. 542-549
-
-
Rohrer, J.D.1
Warren, J.D.2
-
30
-
-
80052282557
-
Genetic contributors to frontotemporal lobar degeneration: Beyond monogenic disease
-
Borroni B, Pilotto A, Bianchi M, Gilberti N, Padovani A. Genetic contributors to frontotemporal lobar degeneration: beyond monogenic disease. Mini Rev Med Chem. 2011;11(11):988-1001.
-
(2011)
Mini Rev Med Chem.
, vol.11
, Issue.11
, pp. 988-1001
-
-
Borroni, B.1
Pilotto, A.2
Bianchi, M.3
Gilberti, N.4
Padovani, A.5
-
31
-
-
79952685399
-
Lanctôt K. Memantine in dementia: A review of the current evidence
-
Herrmann N, Li A, Lanctôt K. Memantine in dementia: a review of the current evidence. Expert Opin Pharmacother. 2011;12(5):787-800.
-
(2011)
Expert Opin Pharmacother.
, vol.12
, Issue.5
, pp. 787-800
-
-
Herrmann, N.1
Li, A.2
-
32
-
-
84855613853
-
Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: A pilot clinical trial
-
Craft S, Baker LD, Montine TJ, et al. Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial. Arch Neurol. 2012;69(1):29-38.
-
(2012)
Arch Neurol.
, vol.69
, Issue.1
, pp. 29-38
-
-
Craft, S.1
Baker, L.D.2
Montine, T.J.3
-
33
-
-
58149497521
-
Biochemistry and molecular biology of amyloid beta-protein and the mechanism of Alzheimer's disease
-
Selkoe DJ. Biochemistry and molecular biology of amyloid beta-protein and the mechanism of Alzheimer's disease. Handb Clin Neurol. 2008;89:245-260.
-
(2008)
Handb Clin Neurol
, vol.89
, pp. 245-260
-
-
Selkoe, D.J.1
-
34
-
-
45149105232
-
Substrate-targeting gamma-secretase modulators
-
Kukar TL, Ladd TB, Bann MA, et al. Substrate-targeting gamma-secretase modulators. Nature. 2008;453(7197):925-929.
-
(2008)
Nature.
, vol.453
, Issue.7197
, pp. 925-929
-
-
Kukar, T.L.1
Ladd, T.B.2
Bann, M.A.3
-
35
-
-
72549105935
-
Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: A randomized controlled trial
-
Tarenflurbil Phase 3 Study Group
-
Green RC, Schneider LS, Amato DA, et al; Tarenflurbil Phase 3 Study Group. Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial. JAMA. 2009;302(23):2557-2564.
-
(2009)
JAMA
, vol.302
, Issue.23
, pp. 2557-2564
-
-
Green, R.C.1
Schneider, L.S.2
Amato, D.A.3
-
36
-
-
77951086901
-
Safety and changes in plasma and cerebrospinal fluid amyloid beta after a single administration of an amyloid beta monoclonal antibody in subjects with Alzheimer disease
-
Siemers ER, Friedrich S, Dean RA, et al. Safety and changes in plasma and cerebrospinal fluid amyloid beta after a single administration of an amyloid beta monoclonal antibody in subjects with Alzheimer disease. Clin Neuropharmacol. 2010;33(2):67-73.
-
(2010)
Clin Neuropharmacol
, vol.33
, Issue.2
, pp. 67-73
-
-
Siemers, E.R.1
Friedrich, S.2
Dean, R.A.3
-
37
-
-
83455243383
-
Evaluating semagacestat, a gamma-secretase inhibitor, in a phase III trial
-
doi:10.1016/j.jalz.2011.05.2355
-
Siemers E, Henley D, Sundell K, et al. Evaluating semagacestat, a gamma-secretase inhibitor, in a phase III trial. Alzheimer's & Dementia. 2011;7(4):S484-S485. doi:10.1016/j.jalz.2011.05.2355.
-
(2011)
Alzheimer's & Dementia
, vol.7
, Issue.4
-
-
Siemers, E.1
Henley, D.2
Sundell, K.3
-
38
-
-
0842309491
-
Beta-Secretase inhibition for the treatment of Alzheimer's disease - Promise and challenge
-
DOI 10.1016/j.tips.2003.12.004
-
Citron M. Beta-secretase inhibition for the treatment of Alzheimer's disease - promise and challenge. Trends Pharmacol Sci. 2004;25(2):92-97. (Pubitemid 38183395)
-
(2004)
Trends in Pharmacological Sciences
, vol.25
, Issue.2
, pp. 92-97
-
-
Citron, M.1
-
39
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer disease-like pathology in the PDAPP mouse
-
DOI 10.1038/22124
-
Schenk D, Barbour R, Dunn W, et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 1999;400(6740):173-177. (Pubitemid 29327547)
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guldo, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
40
-
-
14244255355
-
Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage
-
Wilcock DM, Rojiani A, Rosenthal A, et al. Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage. J Neuroinflammation. 2004;1(1):24.
-
(2004)
J Neuroinflammation.
, vol.1
, Issue.1
, pp. 24
-
-
Wilcock, D.M.1
Rojiani, A.2
Rosenthal, A.3
-
41
-
-
20944448555
-
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial
-
DOI 10.1212/01.WNL.0000159740.16984.3C
-
Gilman S, Koller M, Black RS, et al; AN1792(QS-21)-201 Study Team. Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial. Neurology. 2005;64(9):1553-1562. (Pubitemid 40617691)
-
(2005)
Neurology
, vol.64
, Issue.9
, pp. 1553-1562
-
-
Gilman, S.1
Koller, M.2
Black, R.S.3
Jenkins, L.4
Griffith, S.G.5
Fox, N.C.6
Eisner, L.7
Kirby, L.8
Boada, R.M.9
Forette, F.10
Orgogozo, J.-M.11
-
42
-
-
64549152492
-
Long-term follow-up of patients immunized with AN1792: Reduced functional decline in antibody responders
-
AN1792 (QS-21)-251 Study Team
-
Vellas B, Black R, Thal LJ, et al; AN1792 (QS-21)-251 Study Team. Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders. Curr Alzheimer Res. 2009;6(2):144-151.
-
(2009)
Curr Alzheimer Res
, vol.6
, Issue.2
, pp. 144-151
-
-
Vellas, B.1
Black, R.2
Thal, L.J.3
-
43
-
-
47149112621
-
42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
-
DOI 10.1016/S0140-6736(08)61075-2, PII S0140673608610752
-
Holmes C, Boche D, Wilkinson D, et al. Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet. 2008;372(9634):216-223. (Pubitemid 351978111)
-
(2008)
The Lancet
, vol.372
, Issue.9634
, pp. 216-223
-
-
Holmes, C.1
Boche, D.2
Wilkinson, D.3
Yadegarfar, G.4
Hopkins, V.5
Bayer, A.6
Jones, R.W.7
Bullock, R.8
Love, S.9
Neal, J.W.10
Zotova, E.11
Nicoll, J.A.12
-
44
-
-
77951893095
-
Beneficial effect of human antiamyloid-beta active immunization on neurite morphology and tau pathology
-
Serrano-Pozo A, William CM, Ferrer I, et al. Beneficial effect of human antiamyloid-beta active immunization on neurite morphology and tau pathology. Brain. 2010;133(pt 5):1312-1327.
-
(2010)
Brain.
, vol.133
, Issue.PART 5
, pp. 1312-1327
-
-
Serrano-Pozo, A.1
William, C.M.2
Ferrer, I.3
-
45
-
-
33645013015
-
Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease
-
DOI 10.1212/01.WNL.0000198762.41312.E1, PII 0000611420060228000036
-
Siemers ER, Quinn JF, Kaye J, et al. Effects of a gamma-secretase inhibitor in a randomized study of patients with Alzheimer disease. Neurology. 2006;66(4):602-604. (Pubitemid 43739900)
-
(2006)
Neurology
, vol.66
, Issue.4
, pp. 602-604
-
-
Siemers, E.R.1
Quinn, J.F.2
Kaye, J.3
Farlow, M.R.4
Porsteinsson, A.5
Tariot, P.6
Zoulnouni, P.7
Galvin, J.E.8
Holtzman, D.M.9
Knopman, D.S.10
Satterwhite, J.11
Gonzales, C.12
Dean, R.A.13
May, P.C.14
-
46
-
-
70049083865
-
18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease
-
Relkin NR, Szabo P, Adamiak B, et al. 18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease. Neurobiol Aging. 2009;30(11):1728-1736.
-
(2009)
Neurobiol Aging.
, vol.30
, Issue.11
, pp. 1728-1736
-
-
Relkin, N.R.1
Szabo, P.2
Adamiak, B.3
-
47
-
-
85027951959
-
DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation
-
Lambracht-Washington D, Qu BX, Fu M, et al. DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation. Cell Mol Neurobiol. 2011;31(6):867-874.
-
(2011)
Cell Mol Neurobiol.
, vol.31
, Issue.6
, pp. 867-874
-
-
Lambracht-Washington, D.1
Qu, B.X.2
Fu, M.3
-
48
-
-
34547735385
-
Nerve growth factor gene delivery: Animal models to clinical trials
-
DOI 10.1002/dneu.20510
-
Tuszynski MH. Nerve growth factor gene delivery: animal models to clinical trials. Dev Neurobiol. 2007;67(9):1204-1215. (Pubitemid 47229868)
-
(2007)
Developmental Neurobiology
, vol.67
, Issue.9
, pp. 1204-1215
-
-
Tuszynski, M.H.1
-
49
-
-
79952182383
-
Potential therapeutic uses of BDNF in neurological and psychiatric disorders
-
Nagahara AH, Tuszynski MH. Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nat Rev Drug Discov. 2011;10(3):209-219.
-
(2011)
Nat Rev Drug Discov.
, vol.10
, Issue.3
, pp. 209-219
-
-
Nagahara, A.H.1
Tuszynski, M.H.2
-
50
-
-
62149105940
-
Safety and efficacy of quinacrine in human prion disease (PRION-1 study): A patient-preference trial
-
Collinge J, Gorham M, Hudson F, et al. Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial. Lancet Neurol. 2009;8(4):334-344.
-
(2009)
Lancet Neurol
, vol.8
, Issue.4
, pp. 334-344
-
-
Collinge, J.1
Gorham, M.2
Hudson, F.3
-
51
-
-
62549158694
-
Clinical trials for prion disease: Difficult challenges, but hope for the future
-
Geschwind MD. Clinical trials for prion disease: difficult challenges, but hope for the future. Lancet Neurol. 2009;8(4):304-306.
-
(2009)
Lancet Neurol.
, vol.8
, Issue.4
, pp. 304-306
-
-
Geschwind, M.D.1
|