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Volumn 8, Issue 4, 2009, Pages 304-306

Clinical trials for prion disease: difficult challenges, but hope for the future

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; FLUPIRTINE; MEPACRINE; PENICILLIN G;

EID: 62549158694     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(09)70050-X     Document Type: Letter
Times cited : (22)

References (11)
  • 1
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    • Shattuck lecture-neurodegenerative diseases and prions
    • Prusiner S.B. Shattuck lecture-neurodegenerative diseases and prions. N Engl J Med 344 (2001) 1516-1526
    • (2001) N Engl J Med , vol.344 , pp. 1516-1526
    • Prusiner, S.B.1
  • 2
    • 33749236787 scopus 로고    scopus 로고
    • A systematic review of prion therapeutics in experimental models
    • Trevitt C.R., and Collinge J. A systematic review of prion therapeutics in experimental models. Brain 129 (2006) 2241-2265
    • (2006) Brain , vol.129 , pp. 2241-2265
    • Trevitt, C.R.1    Collinge, J.2
  • 3
    • 62549163241 scopus 로고    scopus 로고
    • Intraventricular pentosan polysulfate in human prion diseases
    • Unit UKCS, ed. Edinburgh, UK
    • Bone I. Intraventricular pentosan polysulfate in human prion diseases. A study of experience in the United Kingdom. In: Unit UKCS, ed. Edinburgh, UK, 2006: 1-11.
    • (2006) A study of experience in the United Kingdom , pp. 1-11
    • Bone, I.1
  • 4
    • 0035859806 scopus 로고    scopus 로고
    • Acridine and phenothiazine derivatives as pharmacoptherapeutics for prion disease
    • Korth C., May B.C.H., Cohen F.E., and Prusiner S.B. Acridine and phenothiazine derivatives as pharmacoptherapeutics for prion disease. Proc Natl Acad Sci USA 98 (2001) 9836-9841
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9836-9841
    • Korth, C.1    May, B.C.H.2    Cohen, F.E.3    Prusiner, S.B.4
  • 5
    • 10744219944 scopus 로고    scopus 로고
    • Efficacy of flupirtine on cognitive function in patients with CJD: a double-blind study
    • Otto M., Cepek L., Ratzka P., et al. Efficacy of flupirtine on cognitive function in patients with CJD: a double-blind study. Neurology 62 (2004) 714-718
    • (2004) Neurology , vol.62 , pp. 714-718
    • Otto, M.1    Cepek, L.2    Ratzka, P.3
  • 6
    • 62149105940 scopus 로고    scopus 로고
    • Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial
    • Collinge J., Gorham M., Hudson F., et al. Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial. Lancet Neurol 8 (2009) 334-344
    • (2009) Lancet Neurol , vol.8 , pp. 334-344
    • Collinge, J.1    Gorham, M.2    Hudson, F.3
  • 7
    • 0014008905 scopus 로고
    • Quinacrine effects on the central nervous system
    • Engel G.L. Quinacrine effects on the central nervous system. JAMA 197 (1966) 505
    • (1966) JAMA , vol.197 , pp. 505
    • Engel, G.L.1
  • 8
    • 19944375077 scopus 로고    scopus 로고
    • Compassionate use of quinacrine in Creutzfeldt-Jakob disease fails to show significant effects
    • Haik S., Brandel J.P., Salomon D., et al. Compassionate use of quinacrine in Creutzfeldt-Jakob disease fails to show significant effects. Neurology 63 (2004) 2413-2415
    • (2004) Neurology , vol.63 , pp. 2413-2415
    • Haik, S.1    Brandel, J.P.2    Salomon, D.3
  • 9
    • 1542405248 scopus 로고    scopus 로고
    • Results of quinacrine administration to patients with Creutzfeldt-Jakob disease
    • Nakajima M., Yamada T., Kusuhara T., et al. Results of quinacrine administration to patients with Creutzfeldt-Jakob disease. Dement Geriatr Cogn Disord 17 (2004) 158-163
    • (2004) Dement Geriatr Cogn Disord , vol.17 , pp. 158-163
    • Nakajima, M.1    Yamada, T.2    Kusuhara, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.