-
1
-
-
33645081239
-
QT PRODACT: In vivo QT assay with a conscious monkey for assessment of the potential for drug-induced QT interval prolongation
-
Ando K., Hombo T., Kanno A., Ikeda H., Imaizumi M., Shimizu N., et al. QT PRODACT: In vivo QT assay with a conscious monkey for assessment of the potential for drug-induced QT interval prolongation. Journal of Pharmacological Sciences 2005, 99:487-500.
-
(2005)
Journal of Pharmacological Sciences
, vol.99
, pp. 487-500
-
-
Ando, K.1
Hombo, T.2
Kanno, A.3
Ikeda, H.4
Imaizumi, M.5
Shimizu, N.6
-
2
-
-
0001127258
-
An analysis of the time-relations of electrocardiograms
-
353-370
-
Bazett H.C. An analysis of the time-relations of electrocardiograms. Heart 1920, 7. 353-370.
-
(1920)
Heart
, vol.7
-
-
Bazett, H.C.1
-
3
-
-
68249140219
-
Effects of CP-532,623 and torcetrapib, cholesteryl ester transfer protein inhibitors, on arterial blood pressure
-
Blasi E., Bamberger M., Knight D., Engwall M., Wolk R., Winter S., et al. Effects of CP-532,623 and torcetrapib, cholesteryl ester transfer protein inhibitors, on arterial blood pressure. Journal of Cardiovascular Pharmacology 2009, 53:507-516.
-
(2009)
Journal of Cardiovascular Pharmacology
, vol.53
, pp. 507-516
-
-
Blasi, E.1
Bamberger, M.2
Knight, D.3
Engwall, M.4
Wolk, R.5
Winter, S.6
-
4
-
-
77953681386
-
Preclinical development of monoclonal antibodies: Considerations for the use of non-human primates
-
Chapman K., Pullen N., Coney L., Dempster M., Andrews L., Bajramovic J., et al. Preclinical development of monoclonal antibodies: Considerations for the use of non-human primates. MAbs 2009, 1:505-516.
-
(2009)
MAbs
, vol.1
, pp. 505-516
-
-
Chapman, K.1
Pullen, N.2
Coney, L.3
Dempster, M.4
Andrews, L.5
Bajramovic, J.6
-
5
-
-
68549134977
-
Assessment of two external telemetry systems (PhysioJacket and JET) in beagle dogs with telemetry implants
-
Chui R.W., Fosdick A., Conner R., Jiang J., Bruenner B.A., Vargas H.M. Assessment of two external telemetry systems (PhysioJacket and JET) in beagle dogs with telemetry implants. Journal of Pharmacological and Toxicological Methods 2009, 60:58-68.
-
(2009)
Journal of Pharmacological and Toxicological Methods
, vol.60
, pp. 58-68
-
-
Chui, R.W.1
Fosdick, A.2
Conner, R.3
Jiang, J.4
Bruenner, B.A.5
Vargas, H.M.6
-
7
-
-
77956060650
-
Normal prevalence of cardiac arrhythmias in 24h ECG recordings of chronically telemetered, healthy, freely moving beagle dogs
-
(Abstract)
-
Cools F., Gallacher D.J. Normal prevalence of cardiac arrhythmias in 24h ECG recordings of chronically telemetered, healthy, freely moving beagle dogs. Journal of Pharmacological and Toxicological Methods 2009, 60:235-236. (Abstract).
-
(2009)
Journal of Pharmacological and Toxicological Methods
, vol.60
, pp. 235-236
-
-
Cools, F.1
Gallacher, D.J.2
-
8
-
-
79960994810
-
ECG arrhythmias in non-implanted vs. telemetry-implanted dogs: Need for screening before and sufficient recovery time after implantation
-
Cools F., Janssens S., Vanlommel A., Teisman A., Towart R., Gallacher D.J. ECG arrhythmias in non-implanted vs. telemetry-implanted dogs: Need for screening before and sufficient recovery time after implantation. Journal of Pharmacological and Toxicological Methods 2011, 64:60-67.
-
(2011)
Journal of Pharmacological and Toxicological Methods
, vol.64
, pp. 60-67
-
-
Cools, F.1
Janssens, S.2
Vanlommel, A.3
Teisman, A.4
Towart, R.5
Gallacher, D.J.6
-
9
-
-
84934988760
-
Evaluation of cardiac conduction disturbances using jacketed external telemetry (JET) in conscious non-human primates (NHP)
-
Derakhchan K., Chui R.W., Vargas H.M. Evaluation of cardiac conduction disturbances using jacketed external telemetry (JET) in conscious non-human primates (NHP). Journal of Pharmacological and Toxicological Methods 2011, 64:e46.
-
(2011)
Journal of Pharmacological and Toxicological Methods
, vol.64
-
-
Derakhchan, K.1
Chui, R.W.2
Vargas, H.M.3
-
10
-
-
33947181047
-
Prevalence of perioperative arrhythmias in 50 young, healthy dogs
-
Duerr F.M., Carr A.P., Duke T., Shmon C.L., Monnet E. Prevalence of perioperative arrhythmias in 50 young, healthy dogs. Canadian Veterinary Journal 2007, 48:169-177.
-
(2007)
Canadian Veterinary Journal
, vol.48
, pp. 169-177
-
-
Duerr, F.M.1
Carr, A.P.2
Duke, T.3
Shmon, C.L.4
Monnet, E.5
-
11
-
-
33644534168
-
Electrocardiogram, hemodynamics, and core body temperatures of the normal freely moving cynomolgus monkey by remote telemetry
-
Gauvin D.V., Tilley L.P., Smith F.W., Baird T.J. Electrocardiogram, hemodynamics, and core body temperatures of the normal freely moving cynomolgus monkey by remote telemetry. Journal of Pharmacological and Toxicological Methods 2006, 53:140-151.
-
(2006)
Journal of Pharmacological and Toxicological Methods
, vol.53
, pp. 140-151
-
-
Gauvin, D.V.1
Tilley, L.P.2
Smith, F.W.3
Baird, T.J.4
-
12
-
-
63749108888
-
Spontaneous arrhythmias recorded in three experimentally- and drug-naïve laboratory species (canine, primate, swine) during standard pre-study screening
-
Gauvin D.V., Tilley L.P., Smith F.W.K., Baird T.J. Spontaneous arrhythmias recorded in three experimentally- and drug-naïve laboratory species (canine, primate, swine) during standard pre-study screening. Journal of Pharmacological and Toxicological Methods 2009, 59:57-61.
-
(2009)
Journal of Pharmacological and Toxicological Methods
, vol.59
, pp. 57-61
-
-
Gauvin, D.V.1
Tilley, L.P.2
Smith, F.W.K.3
Baird, T.J.4
-
13
-
-
22444435916
-
Non-drug-related electrocardiographic features in animal models in safety pharmacology
-
Hamlin R.L. Non-drug-related electrocardiographic features in animal models in safety pharmacology. Journal of Pharmacological and Toxicological Methods 2005, 52:60-76.
-
(2005)
Journal of Pharmacological and Toxicological Methods
, vol.52
, pp. 60-76
-
-
Hamlin, R.L.1
-
14
-
-
48149097711
-
The cardiovascular and pharmacokinetic profile of dofetilide in conscious telemetered beagle dogs and cynomolgus monkeys
-
Haushalter T.M., Friedrichs G.S., Reynolds D.L., Barecki-Roach M., Pastino G., Hayes R., et al. The cardiovascular and pharmacokinetic profile of dofetilide in conscious telemetered beagle dogs and cynomolgus monkeys. British Journal of Pharmacology 2008, 154:1457-1464.
-
(2008)
British Journal of Pharmacology
, vol.154
, pp. 1457-1464
-
-
Haushalter, T.M.1
Friedrichs, G.S.2
Reynolds, D.L.3
Barecki-Roach, M.4
Pastino, G.5
Hayes, R.6
-
15
-
-
0028578687
-
Relationship between QaT and RR intervals in rats, guinea pigs, rabbits, and primates
-
Hayes E., Pugsley M.K., Penz W.P., Adaikan G., Walker M.J.A. Relationship between QaT and RR intervals in rats, guinea pigs, rabbits, and primates. Journal of Pharmacological and Toxicological Methods 1994, 32:201-207.
-
(1994)
Journal of Pharmacological and Toxicological Methods
, vol.32
, pp. 201-207
-
-
Hayes, E.1
Pugsley, M.K.2
Penz, W.P.3
Adaikan, G.4
Walker, M.J.A.5
-
16
-
-
77956059818
-
Left thoracotomy surgical approach for chronic instrumentation in dogs and monkeys providing high-quality electrocardiogram signals
-
Henriques T.A., Beck T.W., Douglas C.L., Jones H.M., Kremer J.J., Kruzich P.J., et al. Left thoracotomy surgical approach for chronic instrumentation in dogs and monkeys providing high-quality electrocardiogram signals. Journal of Pharmacological and Toxicological Methods 2010, 62:136-142.
-
(2010)
Journal of Pharmacological and Toxicological Methods
, vol.62
, pp. 136-142
-
-
Henriques, T.A.1
Beck, T.W.2
Douglas, C.L.3
Jones, H.M.4
Kremer, J.J.5
Kruzich, P.J.6
-
17
-
-
84865655443
-
ICH E14 Expert working group (efficacy) of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH)
-
ICH E14 Expert working group (efficacy) of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). Clinical evaluation of QT/QTc interval prolongation and proarrhythmia potential for non-antiarrhythmic drugs 2005.
-
(2005)
Clinical evaluation of QT/QTc interval prolongation and proarrhythmia potential for non-antiarrhythmic drugs
-
-
-
19
-
-
84862777353
-
Circadian rhythms govern cardiac repolarization and arrhythmogenesis
-
Jeyaraj D., Haldar S.M., Wan X., McCauley M.D., Ripperger J.A., Hu K., et al. Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature 2012, 483:96-99.
-
(2012)
Nature
, vol.483
, pp. 96-99
-
-
Jeyaraj, D.1
Haldar, S.M.2
Wan, X.3
McCauley, M.D.4
Ripperger, J.A.5
Hu, K.6
-
20
-
-
84873089837
-
Comparison of ECG signals and arrhythmia detection using jacketed external telemetry and implanted telemetry in monkeys
-
Kremer J.J., Foley C.M., Xiang Z., Lemke E., Sarazan R.D., Osinski M.A., et al. Comparison of ECG signals and arrhythmia detection using jacketed external telemetry and implanted telemetry in monkeys. Journal of Pharmacological and Toxicological Methods 2011, 64:e47.
-
(2011)
Journal of Pharmacological and Toxicological Methods
, vol.64
-
-
Kremer, J.J.1
Foley, C.M.2
Xiang, Z.3
Lemke, E.4
Sarazan, R.D.5
Osinski, M.A.6
-
21
-
-
84861481556
-
Best practice in the conduct of key nonclinical cardiovascular assessments in drug development: Current recommendations from the Safety Pharmacology Society
-
Leishman D.J., Beck T.W., Dybdal N., Gallacher D.J., Guth B.D., Holbrook M., Roche B., Wallis R.M. Best practice in the conduct of key nonclinical cardiovascular assessments in drug development: Current recommendations from the Safety Pharmacology Society. Journal of Pharmacological and Toxicological Methods 2012, 65:93-101.
-
(2012)
Journal of Pharmacological and Toxicological Methods
, vol.65
, pp. 93-101
-
-
Leishman, D.J.1
Beck, T.W.2
Dybdal, N.3
Gallacher, D.J.4
Guth, B.D.5
Holbrook, M.6
Roche, B.7
Wallis, R.M.8
-
22
-
-
0027546516
-
Characterization of cardiac alterations in nonsedated cynomolgus monkeys
-
Macallum G.E., Houston B.J. Characterization of cardiac alterations in nonsedated cynomolgus monkeys. American Journal of Veterinary Research 1993, 54:327-332.
-
(1993)
American Journal of Veterinary Research
, vol.54
, pp. 327-332
-
-
Macallum, G.E.1
Houston, B.J.2
-
23
-
-
77951612629
-
Evaluation of ventricular arrhythmias in early clinical pharmacology trials and potential consequences for later development
-
Min S.S., Turner J.R., Nada A., DiMino T.L., Hynie I., Kleiman R., et al. Evaluation of ventricular arrhythmias in early clinical pharmacology trials and potential consequences for later development. American Heart Journal 2010, 159:716-729.
-
(2010)
American Heart Journal
, vol.159
, pp. 716-729
-
-
Min, S.S.1
Turner, J.R.2
Nada, A.3
DiMino, T.L.4
Hynie, I.5
Kleiman, R.6
-
25
-
-
33645063232
-
QT PRODACT: Inter-facility variability in electrocardiographic and hemodynamic parameters in conscious dogs and monkeys
-
Sasaki H., Shimizu N., Suganami H., Yamamoto K. QT PRODACT: Inter-facility variability in electrocardiographic and hemodynamic parameters in conscious dogs and monkeys. Journal of Pharmacological Science 2005, 99:513-522.
-
(2005)
Journal of Pharmacological Science
, vol.99
, pp. 513-522
-
-
Sasaki, H.1
Shimizu, N.2
Suganami, H.3
Yamamoto, K.4
-
26
-
-
77956235290
-
Primate models for cardiovascular drug research and development
-
Shen Y.T. Primate models for cardiovascular drug research and development. Current Opinion in Investigational Drugs 2010, 11:1025-1029.
-
(2010)
Current Opinion in Investigational Drugs
, vol.11
, pp. 1025-1029
-
-
Shen, Y.T.1
-
27
-
-
33847174126
-
Different species require different correction factors for the QT interval
-
Soloviev M.V., Hamlin R.L., Barrett R.M., Chengelis C.P., Schaefer G.J. Different species require different correction factors for the QT interval. Cardiovascular Toxicology 2006, 6:145-157.
-
(2006)
Cardiovascular Toxicology
, vol.6
, pp. 145-157
-
-
Soloviev, M.V.1
Hamlin, R.L.2
Barrett, R.M.3
Chengelis, C.P.4
Schaefer, G.J.5
-
28
-
-
48149111313
-
Sensitive and reliable proarrhythmia in vivo animal models for predicting drug-induced torsades de pointes in patients with remodeled hearts
-
Sugiyama A. Sensitive and reliable proarrhythmia in vivo animal models for predicting drug-induced torsades de pointes in patients with remodeled hearts. British Journal of Pharmacology 2008, 154:1528-1537.
-
(2008)
British Journal of Pharmacology
, vol.154
, pp. 1528-1537
-
-
Sugiyama, A.1
-
30
-
-
77952484146
-
Spontaneous findings in the heart of Mauritian-origin cynomolgus macaques (Macaca fascicularis)
-
Vidal J.D., Drobatz L.S., Holliday D.F., Geiger L.E., Thomas H.C. Spontaneous findings in the heart of Mauritian-origin cynomolgus macaques (Macaca fascicularis). Toxicologic Pathology 2010, 38:297-302.
-
(2010)
Toxicologic Pathology
, vol.38
, pp. 297-302
-
-
Vidal, J.D.1
Drobatz, L.S.2
Holliday, D.F.3
Geiger, L.E.4
Thomas, H.C.5
-
31
-
-
85047679058
-
The Lambeth Conventions: Guidelines for the study of arrhythmias in ischaemia, infarction, and reperfusion
-
Walker M.J.A., Curtis M.J., Hearse D.J., Campbell R.W.F., Janse M.J., Yellon D.M., et al. The Lambeth Conventions: Guidelines for the study of arrhythmias in ischaemia, infarction, and reperfusion. Cardiovascular Research 1988, 22:447-455.
-
(1988)
Cardiovascular Research
, vol.22
, pp. 447-455
-
-
Walker, M.J.A.1
Curtis, M.J.2
Hearse, D.J.3
Campbell, R.W.F.4
Janse, M.J.5
Yellon, D.M.6
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