메뉴 건너뛰기




Volumn 53, Issue 6, 2009, Pages 507-516

Effects of CP-532,623 and torcetrapib, cholesteryl ester transfer protein inhibitors, on arterial blood pressure

Author keywords

Atherosclerosis; Blood pressure; CETP inhibitor; Cholesterol; Hypertension

Indexed keywords

ALDOSTERONE; CHOLESTEROL ESTER TRANSFER PROTEIN INHIBITOR; CP 529 414; CP 532 623; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TORCETRAPIB; UNCLASSIFIED DRUG;

EID: 68249140219     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e3181a8184c     Document Type: Article
Times cited : (22)

References (27)
  • 1
    • 0024449985 scopus 로고
    • High-density lipoprotein-the clinical implications of recent studies
    • Gordon DJ, Rifkind BM. High-density lipoprotein-the clinical implications of recent studies. N Engl J Med. 1989;321:1311-1316.
    • (1989) N Engl J Med , vol.321 , pp. 1311-1316
    • Gordon, D.J.1    Rifkind, B.M.2
  • 2
    • 0037327033 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein: A novel target for raising HDL and inhibiting atherosclerosis
    • Barter PJ, BH Jr, Chapman MJ, et al. Cholesteryl ester transfer protein: a novel target for raising HDL and inhibiting atherosclerosis. Arterioscler Thromb Vasc Biol. 2003;23:160-167.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 160-167
    • Barter, P.J.1    H Jr., B.2    Chapman, M.J.3
  • 3
    • 1842765494 scopus 로고    scopus 로고
    • Increasing HDL cholesterol levels
    • Brewer HB Jr. Increasing HDL cholesterol levels. N Engl J Med. 2004; 350:1491-1494.
    • (2004) N Engl J Med , vol.350 , pp. 1491-1494
    • Brewer Jr., H.B.1
  • 4
    • 0032570684 scopus 로고    scopus 로고
    • Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits
    • DOI 10.1074/jbc.273.9.5033
    • Sugano M, Makino N, Sawada S, et al. Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits. J Biol Chem. 1998;273:5033-5036. (Pubitemid 28108660)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.9 , pp. 5033-5036
    • Sugano, M.1    Makino, N.2    Sawada, S.3    Otsuka, S.4    Watanabe, M.5    Okamoto, H.6    Kamada, M.7    Mizushima, A.8
  • 5
    • 0034644214 scopus 로고    scopus 로고
    • A cholesteryl ester transfer protein inhibitor attenuate atherosclerosis in rabbits
    • DOI 10.1038/35018119
    • Okamoto H, Yonemori F, Wakitani K, et al. A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature. 2000;406: 203-207. (Pubitemid 30469005)
    • (2000) Nature , vol.406 , Issue.6792 , pp. 203-207
    • Okamoto, H.1    Yonemori, F.2    Wakitani, K.3    Minowa, T.4    Maeda, K.5    Shinkai, H.6
  • 6
    • 34447266483 scopus 로고    scopus 로고
    • Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits
    • Morehouse LA, Sugarman ED, Bourassa PA, et al. Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits. J Lipid Res. 2007;48:1263-1272.
    • (2007) J Lipid Res , vol.48 , pp. 1263-1272
    • Morehouse, L.A.1    Sugarman, E.D.2    Bourassa, P.A.3
  • 7
    • 43449114204 scopus 로고    scopus 로고
    • Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin
    • de Haan W, de Vries-van der Weij J, van der Hoorn JW, et al. Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin. Circulation. 2008;117: 2515-2522.
    • (2008) Circulation , vol.117 , pp. 2515-2522
    • De Haan, W.1    De Vries-Van Der Weij, J.2    Van Der Hoorn, J.W.3
  • 8
    • 33644775588 scopus 로고    scopus 로고
    • Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of action
    • DOI 10.1194/jlr.M500349-JLR200
    • Clark RW, Ruggeri RB, Cunningham D, et al. Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of action. J Lipid Res. 2006;47:537-552. (Pubitemid 43345595)
    • (2006) Journal of Lipid Research , vol.47 , Issue.3 , pp. 537-552
    • Clark, R.W.1    Ruggeri, R.B.2    Cunningham, D.3    Bamberger, M.J.4
  • 10
    • 33750447972 scopus 로고    scopus 로고
    • Efficacy and Safety of Torcetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor, in Individuals with Below-Average High-Density Lipoprotein Cholesterol Levels on a Background of Atorvastatin
    • DOI 10.1016/j.jacc.2006.06.066, PII S0735109706019905
    • McKenney JM, Davidson MH, Shear CL, et al. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels on a background of atorvastatin. J Am Coll Cardiol. 2006;48:1782-1790. (Pubitemid 44648632)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.9 , pp. 1782-1790
    • McKenney, J.M.1    Davidson, M.H.2    Shear, C.L.3    Revkin, J.H.4
  • 14
    • 34447265547 scopus 로고    scopus 로고
    • Torcetrapib and carotid intimamedia thickness in mixed dyslipidemia (RADIANCE 2 study): A randomized, double-blind trial
    • Bots ML, Visseren FL, Evans GW, et al. Torcetrapib and carotid intimamedia thickness in mixed dyslipidemia (RADIANCE 2 study): a randomized, double-blind trial. Lancet. 2007;370:153-160.
    • (2007) Lancet , vol.370 , pp. 153-160
    • Bots, M.L.1    Visseren, F.L.2    Evans, G.W.3
  • 17
    • 54349100968 scopus 로고    scopus 로고
    • Pharmacokinetics, metabolism, and excretion of torcetrapib, a cholesteryl ester transfer protein inhibitor, in humans
    • Dalvie D, Chen W, Zhang C, et al. Pharmacokinetics, metabolism, and excretion of torcetrapib, a cholesteryl ester transfer protein inhibitor, in humans. Drug Metab Dispos. 2008;36:2185-2198.
    • (2008) Drug Metab Dispos , vol.36 , pp. 2185-2198
    • Dalvie, D.1    Chen, W.2    Zhang, C.3
  • 18
    • 12144287356 scopus 로고    scopus 로고
    • Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein
    • Clark RW, Sutfin TA, Ruggeri RB, et al. Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein. Arterioscler, Thromb Vasc Biol. 2004;24:490-497.
    • (2004) Arterioscler, Thromb Vasc Biol , vol.24 , pp. 490-497
    • Clark, R.W.1    Sutfin, T.A.2    Ruggeri, R.B.3
  • 20
    • 61349154804 scopus 로고    scopus 로고
    • Mechanistic studies of blood pressure in rats treated with a series of cholesteryl ester transfer protein inhibitors
    • DePasquale M, Cadelina G, Knight DR, et al. Mechanistic studies of blood pressure in rats treated with a series of cholesteryl ester transfer protein inhibitors. Drug Dev Res. 2009;70:35-48.
    • (2009) Drug Dev Res , vol.70 , pp. 35-48
    • Depasquale, M.1    Cadelina, G.2    Knight, D.R.3
  • 21
    • 48149106322 scopus 로고    scopus 로고
    • Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone
    • Forrest MJ, Bloomfield D, Briscoe RJ, et al. Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone. Br J Pharmacol. 2008;154: 1465-1473.
    • (2008) Br J Pharmacol , vol.154 , pp. 1465-1473
    • Forrest, M.J.1    Bloomfield, D.2    Briscoe, R.J.3
  • 22
    • 58149386896 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis. Insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation)
    • Nicholls SJ, Tuzcu EM, Brennan DM, et al. Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis. Insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation). Circulation. 2008;118:2506-2514.
    • (2008) Circulation , vol.118 , pp. 2506-2514
    • Nicholls, S.J.1    Tuzcu, E.M.2    Brennan, D.M.3
  • 23
    • 58149380516 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein inhibitor torcetrapib and off-target toxicity. A pooled analysis of the rating atherosclerotic disease change by imaging with a new CETP inhibitor (RADIANCE) trials
    • CIRCULATIONAHA. 108.772665
    • Vergeer M, Bots ML, van Leuven SI, et al. Cholesteryl ester transfer protein inhibitor torcetrapib and off-target toxicity. A pooled analysis of the rating atherosclerotic disease change by imaging with a new CETP inhibitor (RADIANCE) trials. Circulation. 2008:CIRCULATIONAHA. 108.772665.
    • (2008) Circulation
    • Vergeer, M.1    Bots, M.L.2    Van Leuven, S.I.3
  • 25
    • 0037035459 scopus 로고    scopus 로고
    • Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study
    • de Grooth GJ, Kuivenhoven JA, Stalenhoef AFH, et al. Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study. Circulation. 2002;105:2159-2165.
    • (2002) Circulation , vol.105 , pp. 2159-2165
    • De Grooth, G.J.1    Kuivenhoven, J.A.2    Stalenhoef, A.F.H.3
  • 26
    • 33750477286 scopus 로고    scopus 로고
    • Efficacy and Safety of Torcetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor, in Individuals with Below-Average High-Density Lipoprotein Cholesterol Levels
    • DOI 10.1016/j.jacc.2006.06.067, PII S0735109706019917
    • Davidson MH, McKenney JM, Shear CL, et al. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels. J Am Coll Cardiol. 2006;48:1774-1781. (Pubitemid 44648633)
    • (2006) Journal of the American College of Cardiology , vol.48 , Issue.9 , pp. 1774-1781
    • Davidson, M.H.1    McKenney, J.M.2    Shear, C.L.3    Revkin, J.H.4
  • 27
    • 66449084532 scopus 로고    scopus 로고
    • Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein (CETP) inhibition
    • Hu X, Dietz JD, Xia C, et al. Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein (CETP) inhibition. Endocrinology. 2009;150:2211-2219.
    • (2009) Endocrinology , vol.150 , pp. 2211-2219
    • Hu, X.1    Dietz, J.D.2    Xia, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.