메뉴 건너뛰기




Volumn 7, Issue 8, 2012, Pages

A Novel Five Gene Signature Derived from Stem-Like Side Population Cells Predicts Overall and Recurrence-Free Survival in NSCLC

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AURKB GENE; BRRN1 GENE; CANCER PATIENT; CANCER RECURRENCE; CANCER RELAPSE; CANCER STEM CELL; CANCER SURVIVAL; CDK1 GENE; CELL ISOLATION; CELL POPULATION; CHROMOSOME CONDENSATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DOWN REGULATION; FUS GENE; GENE; GENE CONTROL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE OVEREXPRESSION; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; OVERALL SURVIVAL; PREDICTION; RECURRENCE FREE SURVIVAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTEMS BIOLOGY; TOP2A GENE; UPREGULATION;

EID: 84865600696     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043589     Document Type: Article
Times cited : (26)

References (55)
  • 3
    • 77950571895 scopus 로고    scopus 로고
    • Gene Expression-Based Prognostic Signatures in Lung Cancer: Ready for Clinical Use?
    • Subramanian J, Simon R, (2010) Gene Expression-Based Prognostic Signatures in Lung Cancer: Ready for Clinical Use? Journal of the National Cancer Institute 102: 464-474.
    • (2010) Journal of the National Cancer Institute , vol.102 , pp. 464-474
    • Subramanian, J.1    Simon, R.2
  • 4
    • 58149356243 scopus 로고    scopus 로고
    • Confirmation of Gene Expression-Based Prediction of Survival in Non-Small Cell Lung Cancer
    • Guo NL, Wan Y-W, Tosun K, Lin H, Msiska Z, et al. (2008) Confirmation of Gene Expression-Based Prediction of Survival in Non-Small Cell Lung Cancer. Clinical Cancer Research 14: 8213-8220.
    • (2008) Clinical Cancer Research , vol.14 , pp. 8213-8220
    • Guo, N.L.1    Wan, Y.-W.2    Tosun, K.3    Lin, H.4    Msiska, Z.5
  • 5
    • 33744502855 scopus 로고    scopus 로고
    • Cancer Biomarkers-An Invitation to the Table
    • Dalton WS, Friend SH, (2006) Cancer Biomarkers-An Invitation to the Table. Science 312: 1165-1168.
    • (2006) Science , vol.312 , pp. 1165-1168
    • Dalton, W.S.1    Friend, S.H.2
  • 6
    • 34248352185 scopus 로고    scopus 로고
    • Markers for early detection of cancer: Statistical guidelines for nested case-control studies
    • Baker SG, Kramer BS, Srivastava S, (2002) Markers for early detection of cancer: Statistical guidelines for nested case-control studies. BMC Medical Research Methodology 2.
    • (2002) BMC Medical Research Methodology , vol.2
    • Baker, S.G.1    Kramer, B.S.2    Srivastava, S.3
  • 7
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer DG, Kardia SLR, Huang C-C, Giordano TJ, Levin AM, et al. (2002) Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 8: 816-824.
    • (2002) Nat Med , vol.8 , pp. 816-824
    • Beer, D.G.1    Kardia, S.L.R.2    Huang, C.-C.3    Giordano, T.J.4    Levin, A.M.5
  • 9
    • 1542608359 scopus 로고    scopus 로고
    • Prognostic Model of Pulmonary Adenocarcinoma by Expression Profiling of Eight Genes As Determined by Quantitative Real-Time Reverse Transcriptase Polymerase Chain Reaction
    • Endoh H, Tomida S, Yatabe Y, Konishi H, Osada H, et al. (2004) Prognostic Model of Pulmonary Adenocarcinoma by Expression Profiling of Eight Genes As Determined by Quantitative Real-Time Reverse Transcriptase Polymerase Chain Reaction. Journal of Clinical Oncology 22: 811-819.
    • (2004) Journal of Clinical Oncology , vol.22 , pp. 811-819
    • Endoh, H.1    Tomida, S.2    Yatabe, Y.3    Konishi, H.4    Osada, H.5
  • 10
    • 33644844520 scopus 로고    scopus 로고
    • Microarray technology: beyond transcript profiling and genotype analysis
    • Hoheisel JD, (2006) Microarray technology: beyond transcript profiling and genotype analysis. Nat Rev Genet 7: 200-210.
    • (2006) Nat Rev Genet , vol.7 , pp. 200-210
    • Hoheisel, J.D.1
  • 12
    • 20444457518 scopus 로고    scopus 로고
    • Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
    • Glinsky GV, Berezovska O, Glinskii AB, (2005) Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. The Journal of Clinical Investigation 115: 1503-1521.
    • (2005) The Journal of Clinical Investigation , vol.115 , pp. 1503-1521
    • Glinsky, G.V.1    Berezovska, O.2    Glinskii, A.B.3
  • 13
    • 33646353175 scopus 로고    scopus 로고
    • The challenges of gene expression microarrays for the study of human cancer
    • Tinker AV, Boussioutas A, Bowtell DDL, (2006) The challenges of gene expression microarrays for the study of human cancer. Cancer Cell 9: 333-339.
    • (2006) Cancer Cell , vol.9 , pp. 333-339
    • Tinker, A.V.1    Boussioutas, A.2    Bowtell, D.D.L.3
  • 14
    • 13444249852 scopus 로고    scopus 로고
    • Prediction of cancer outcome with microarrays: a multiple random validation strategy
    • Michiels S, Koscielny S, Hill C, (2005) Prediction of cancer outcome with microarrays: a multiple random validation strategy. The Lancet 365: 488-492.
    • (2005) The Lancet , vol.365 , pp. 488-492
    • Michiels, S.1    Koscielny, S.2    Hill, C.3
  • 15
    • 20044388557 scopus 로고    scopus 로고
    • From signatures to models: understanding cancer using microarrays
    • Segal E, Friedman N, Kaminski N, Regev A, Koller D, (2005) From signatures to models: understanding cancer using microarrays. Nat Genet 37: S38-S45.
    • (2005) Nat Genet , vol.37
    • Segal, E.1    Friedman, N.2    Kaminski, N.3    Regev, A.4    Koller, D.5
  • 17
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • Zhou S, Schuetz JD, Bunting KD, Colapietro A-M, Sampath J, et al. (2001) The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 7: 1028-1034.
    • (2001) Nat Med , vol.7 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3    Colapietro, A.-M.4    Sampath, J.5
  • 19
    • 34250306257 scopus 로고    scopus 로고
    • Side Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-like Cancer Cells
    • Ho MM, Ng AV, Lam S, Hung JY, (2007) Side Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-like Cancer Cells. Cancer Research 67: 4827-4833.
    • (2007) Cancer Research , vol.67 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 20
    • 49149129916 scopus 로고    scopus 로고
    • Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study
    • Shedden K, Taylor JMG, Enkemann SA, Tsao M-S, Yeatman TJ, et al. (2008) Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med 14: 822-827.
    • (2008) Nat Med , vol.14 , pp. 822-827
    • Shedden, K.1    Taylor, J.M.G.2    Enkemann, S.A.3    Tsao, M.-S.4    Yeatman, T.J.5
  • 21
    • 58149343905 scopus 로고    scopus 로고
    • Prediction of Recurrence-Free Survival in Postoperative Non-Small Cell Lung Cancer Patients by Using an Integrated Model of Clinical Information and Gene Expression
    • Lee E-S, Son D-S, Kim S-H, Lee J, Jo J, et al. (2008) Prediction of Recurrence-Free Survival in Postoperative Non-Small Cell Lung Cancer Patients by Using an Integrated Model of Clinical Information and Gene Expression. Clinical Cancer Research 14: 7397-7404.
    • (2008) Clinical Cancer Research , vol.14 , pp. 7397-7404
    • Lee, E.-S.1    Son, D.-S.2    Kim, S.-H.3    Lee, J.4    Jo, J.5
  • 22
    • 79960466223 scopus 로고    scopus 로고
    • Human SIRT1 associates with mitotic chromatin and contributes to chromosomal condensation
    • Fatoba ST, Okorokov AL, (2011) Human SIRT1 associates with mitotic chromatin and contributes to chromosomal condensation. Cell Cycle 10: 2317-2322.
    • (2011) Cell Cycle , vol.10 , pp. 2317-2322
    • Fatoba, S.T.1    Okorokov, A.L.2
  • 23
    • 79953239469 scopus 로고    scopus 로고
    • Aberrant chromosome morphology in human cells defective for Holliday junction resolution
    • Wechsler T, Newman S, West SC, (2011) Aberrant chromosome morphology in human cells defective for Holliday junction resolution. Nature 471: 642-646.
    • (2011) Nature , vol.471 , pp. 642-646
    • Wechsler, T.1    Newman, S.2    West, S.C.3
  • 24
    • 77957888616 scopus 로고    scopus 로고
    • Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation
    • Stevens J, Abdallah B, Regan S, Liu G, Bremer S, et al. (2010) Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation. Molecular Cytogenetics 3: 20.
    • (2010) Molecular Cytogenetics , vol.3 , pp. 20
    • Stevens, J.1    Abdallah, B.2    Regan, S.3    Liu, G.4    Bremer, S.5
  • 26
    • 0037941536 scopus 로고    scopus 로고
    • Gene expression phenotypic models that predict the activity of oncogenic pathways
    • Huang E, Ishida S, Pittman J, Dressman H, Bild A, et al. (2003) Gene expression phenotypic models that predict the activity of oncogenic pathways. Nat Genet 34: 226-230.
    • (2003) Nat Genet , vol.34 , pp. 226-230
    • Huang, E.1    Ishida, S.2    Pittman, J.3    Dressman, H.4    Bild, A.5
  • 27
    • 33747878451 scopus 로고    scopus 로고
    • Gene Expression Signatures for Predicting Prognosis of Squamous Cell and Adenocarcinomas of the Lung
    • Raponi M, Zhang Y, Yu J, Chen G, Lee G, et al. (2006) Gene Expression Signatures for Predicting Prognosis of Squamous Cell and Adenocarcinomas of the Lung. Cancer Research 66: 7466-7472.
    • (2006) Cancer Research , vol.66 , pp. 7466-7472
    • Raponi, M.1    Zhang, Y.2    Yu, J.3    Chen, G.4    Lee, G.5
  • 28
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild AH, Yao G, Chang JT, Wang Q, Potti A, et al. (2006) Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 439: 353-357.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3    Wang, Q.4    Potti, A.5
  • 29
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S, (2005) Tumour stem cells and drug resistance. Nat Rev Cancer 5: 275-284.
    • (2005) Nat Rev Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 30
    • 4944265743 scopus 로고    scopus 로고
    • Study design considerations in clinical outcome research of lung cancer using microarray analysis
    • Yang P, Sun Z, Aubry MC, Kosari F, Bamlet W, et al. (2004) Study design considerations in clinical outcome research of lung cancer using microarray analysis. Lung Cancer 46: 215-226.
    • (2004) Lung Cancer , vol.46 , pp. 215-226
    • Yang, P.1    Sun, Z.2    Aubry, M.C.3    Kosari, F.4    Bamlet, W.5
  • 32
    • 43049165453 scopus 로고    scopus 로고
    • The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
    • Mani SA, Guo W, Liao M-J, Eaton EN, Ayyanan A, et al. (2008) The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells. Cell 133: 704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.-J.3    Eaton, E.N.4    Ayyanan, A.5
  • 33
    • 84855162618 scopus 로고    scopus 로고
    • The EMT Status in the Primary Tumor Does Not Predict Postoperative Recurrence or Disease-free Survival in Lung Adenocarcinoma
    • Chikaishi Y, Uramoto H, Tanaka F, (2011) The EMT Status in the Primary Tumor Does Not Predict Postoperative Recurrence or Disease-free Survival in Lung Adenocarcinoma. Anticancer Research 31: 4451-4456.
    • (2011) Anticancer Research , vol.31 , pp. 4451-4456
    • Chikaishi, Y.1    Uramoto, H.2    Tanaka, F.3
  • 34
    • 78149447865 scopus 로고    scopus 로고
    • A Comparative Analysis of Gene-Expression Data of Multiple Cancer Types
    • Xu K, Cui J, Olman V, Yang Q, Puett D, et al. (2010) A Comparative Analysis of Gene-Expression Data of Multiple Cancer Types. PLoS ONE 5: e13696.
    • (2010) PLoS ONE , vol.5
    • Xu, K.1    Cui, J.2    Olman, V.3    Yang, Q.4    Puett, D.5
  • 37
    • 33646409018 scopus 로고    scopus 로고
    • Altered Expression Pattern of Topoisomerase IIa in Ovarian Tumor Epithelial and Stromal Cells after Platinum-Based Chemotherapy
    • Chekerov R, Klamany I, Zafrakasz M, Konsgen D, Mustea A, et al. (2006) Altered Expression Pattern of Topoisomerase IIa in Ovarian Tumor Epithelial and Stromal Cells after Platinum-Based Chemotherapy. Neoplasia 8: 38-45.
    • (2006) Neoplasia , vol.8 , pp. 38-45
    • Chekerov, R.1    Klamany, I.2    Zafrakasz, M.3    Konsgen, D.4    Mustea, A.5
  • 39
    • 33748595550 scopus 로고    scopus 로고
    • Topoisomerase IIα gene amplification in gastric carcinomas: correlation with the HER2 gene. An immunohistochemical, immunoblotting, and multicolor fluorescence in situ hybridization study
    • Kanta SY, Yamane T, Dobashi Y, Mitsui F, Kono K, et al. (2006) Topoisomerase IIα gene amplification in gastric carcinomas: correlation with the HER2 gene. An immunohistochemical, immunoblotting, and multicolor fluorescence in situ hybridization study. Human Pathology 37: 1333-1343.
    • (2006) Human Pathology , vol.37 , pp. 1333-1343
    • Kanta, S.Y.1    Yamane, T.2    Dobashi, Y.3    Mitsui, F.4    Kono, K.5
  • 40
    • 3843082080 scopus 로고    scopus 로고
    • Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes
    • Tanaka T, Tanimoto K, Otani K, Satoh K, Ohtaki M, et al. (2004) Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes. International Journal of Cancer 111: 617-626.
    • (2004) International Journal of Cancer , vol.111 , pp. 617-626
    • Tanaka, T.1    Tanimoto, K.2    Otani, K.3    Satoh, K.4    Ohtaki, M.5
  • 41
    • 45749140422 scopus 로고    scopus 로고
    • Gene Expression Signature of Cigarette Smoking and Its Role in Lung Adenocarcinoma Development and Survival
    • Landi MT, Dracheva T, Rotunno M, Figueroa JD, Liu H, et al. (2008) Gene Expression Signature of Cigarette Smoking and Its Role in Lung Adenocarcinoma Development and Survival. PLoS ONE 3: e1651.
    • (2008) PLoS ONE , vol.3
    • Landi, M.T.1    Dracheva, T.2    Rotunno, M.3    Figueroa, J.D.4    Liu, H.5
  • 46
    • 67649662201 scopus 로고    scopus 로고
    • WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
    • Nguyen DX, Chiang AC, Zhang XHF, Kim JY, Kris MG, et al. (2009) WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis. Cell 138: 51-62.
    • (2009) Cell , vol.138 , pp. 51-62
    • Nguyen, D.X.1    Chiang, A.C.2    Zhang, X.H.F.3    Kim, J.Y.4    Kris, M.G.5
  • 49
    • 79959956046 scopus 로고    scopus 로고
    • The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors
    • Marotta LLC, Almendro V, Marusyk A, Shipitsin M, Schemme J, et al. (2011) The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors. The Journal of Clinical Investigation 121: 2723-2735.
    • (2011) The Journal of Clinical Investigation , vol.121 , pp. 2723-2735
    • Marotta, L.L.C.1    Almendro, V.2    Marusyk, A.3    Shipitsin, M.4    Schemme, J.5
  • 50
    • 79952717245 scopus 로고    scopus 로고
    • Genomic and Epigenomic Integration Identifies a Prognostic Signature in Colon Cancer
    • Yi JM, Dhir M, Van Neste L, Downing SR, Jeschke J, et al. (2011) Genomic and Epigenomic Integration Identifies a Prognostic Signature in Colon Cancer. Clinical Cancer Research 17: 1535-1545.
    • (2011) Clinical Cancer Research , vol.17 , pp. 1535-1545
    • Yi, J.M.1    Dhir, M.2    Van Neste, L.3    Downing, S.R.4    Jeschke, J.5
  • 51
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2-ΔΔCT Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2-ΔΔCT Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 52
    • 33747885673 scopus 로고    scopus 로고
    • Bioconductor: An Open Source Framework for Bioinformatics and Computational Biology
    • In: Alan K, Brian O, editors, Academic Press
    • Reimers M, Carey VJ (2006) Bioconductor: An Open Source Framework for Bioinformatics and Computational Biology. In: Alan K, Brian O, editors. Methods in Enzymology: Academic Press. pp. 119-134.
    • (2006) Methods in Enzymology , pp. 119-134
    • Reimers, M.1    Carey, V.J.2
  • 53
    • 40449141013 scopus 로고    scopus 로고
    • What is principal component analysis?
    • Ringner M, (2008) What is principal component analysis? Nat Biotech 26: 303-304.
    • (2008) Nat Biotech , vol.26 , pp. 303-304
    • Ringner, M.1
  • 55
    • 84855199947 scopus 로고    scopus 로고
    • R, Development Core Team, R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0
    • R, Development Core Team (2008) A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0.
    • (2008) A language and environment for statistical computing


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.