Scanning tunneling microscopy reveals single-molecule insights into the self-assembly of amyloid fibrils

ACS Nano

Volumn 6, Issue 8, 2012, Pages 6882-6889

  Kalashnyk, Nataliya ^a,d   Nielsen, Jakob T ^a   Nielsen, Erik H ^a   Skrydstrup, Troels ^a   Otzen, Daniel E ^b   Lægsgaard, Erik ^a   Wang, Chen ^c   Besenbacher, Flemming ^a   Nielsen, Niels Chr ^a   Linderoth, Trolle R ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

^d UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Au(111); biomolecular adsorption; molecular self assembly; peptides; restrained molecular dynamics modeling; scanning tunneling microscopy

Indexed keywords

AMYLOID FIBRIL; AU(1 1 1 ); BIOMOLECULAR ADSORPTION; CONFORMATIONAL HETEROGENEITY; FIBRIL FORMATION; FIBRIL GROWTH; FIBRIL STRUCTURE; GOLD SURFACES; IDEALIZED MODELS; INTERMOLECULAR INTERACTIONS; INTRAMOLECULAR INTERACTIONS; MOLECULAR DYNAMICS MODELING; MOLECULAR SELF ASSEMBLY; PROTEIN MISFOLDING; SINGLE-MOLECULE; STRUCTURAL INFORMATION; SURFACE SCIENCE; TETRA PEPTIDE; VACUUM CONDITION;

ADSORPTION; GLYCOPROTEINS; MOLECULAR DYNAMICS; MOLECULES; PEPTIDES; SCANNING TUNNELING MICROSCOPY; SELF ASSEMBLY;

CONFORMATIONS;

AMYLOID; MULTIPROTEIN COMPLEX;

ARTICLE; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DIMERIZATION; METHODOLOGY; MOLECULAR IMAGING; PROTEIN BINDING; PROTEIN CONFORMATION; SCANNING TUNNELING MICROSCOPY; ULTRASTRUCTURE;

AMYLOID; BINDING SITES; COMPUTER SIMULATION; DIMERIZATION; MICROSCOPY, SCANNING TUNNELING; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR IMAGING; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84865594280     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn301708d     Document Type: Article

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