Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

Biochemical Journal

Volumn 446, Issue 3, 2012, Pages 383-394

  Kim, Kyubo ^a,b   Petrova, Youlia M ^a   Scott, Brenton L ^a   Nigam, Rupesh ^a   Agrawal, Anurag ^a,c   Evans, Christopher M ^a   Azzegagh, Zoulikha ^a   Gomez, Alejandra ^d   Rodarte, Elsa M ^a,d   Olkkonen, Vesa M ^e   Bagirzadeh, Rustam ^a   Piccotti, Lucia ^a   Ren, Binhui ^a   Yoon, Joo Heon ^b   McNew, James A ^f   Adachi, Roberto ^a   Tuvim, Michael J ^a   Dickey, Burton F ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Yonsei University College of Medicine   (South Korea)

^c CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^d ESCUELA DE MEDICINA Y CIENCIAS DE LA SALUD   (Mexico)

^e MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^f RICE UNIVERSITY   (United States)

Author keywords

Exocytosis; Mast cell; Mucin; Mucus; Munc18; Secretion

Indexed keywords

INITIATOR CASPASE; MUCIN; MUNC18B PROTEIN; PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; E BOX ELEMENT; ESSENTIAL GENE; GENE EXPRESSION; GLUCOCORTICOID RESPONSE ELEMENT; HETEROZYGOTE; MAST CELL; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESPIRATORY EPITHELIUM; SECRETORY CELL;

ANIMALS; DISEASE MODELS, ANIMAL; E-BOX ELEMENTS; EPITHELIAL CELLS; FEMALE; GENES, ESSENTIAL; LUNG; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUNC18 PROTEINS; PASSIVE CUTANEOUS ANAPHYLAXIS; RATS;

MUS;

EID: 84865589146     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120057     Document Type: Article

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