Interferon-β-armed oncolytic adenovirus induces both apoptosis and necroptosis in cancer cells

Acta Biochimica et Biophysica Sinica

Volumn 44, Issue 9, 2012, Pages 737-745

  Huang, Hongling ^a   Xiao, Tian ^a   He, Lingfeng ^c   Ji, Hongbin ^a   Liu, Xin Yuan ^b  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b ZHEJIANG SCI TECH UNIVERSITY   (China)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

apoptosis; cell cycle arrest; IFN ; necroptosis; synergism

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; ATM PROTEIN; BETA INTERFERON; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DOXORUBICIN; GREEN FLUORESCENT PROTEIN; ONCOLYTIC VIRUS; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

ADENOVIRUS; APOPTOSIS; ARTICLE; CELL CYCLE CHECKPOINT; CELL CYCLE S PHASE; CELL STRAIN HEK293; CELL STRAIN MCF 7; CELL SURVIVAL; CONFOCAL MICROSCOPY; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MUTATION; NECROSIS; NEOPLASM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; WESTERN BLOTTING;

ADENOVIRIDAE; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; DNA-BINDING PROTEINS; DOXORUBICIN; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; INTERFERON-BETA; MCF-7 CELLS; MICROSCOPY, CONFOCAL; MUTATION; NECROSIS; NEOPLASMS; ONCOLYTIC VIRUSES; PROTEIN-SERINE-THREONINE KINASES; S PHASE; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ADENOVIRIDAE; ATAXIA TELANGIECTASIA;

EID: 84865578619     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gms060     Document Type: Article

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