3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells

Toxicology

Volumn 255, Issue 3, 2009, Pages 140-150

  Asare, Nana ^a   Låg, Marit ^a   Lagadic Gossmann, Dominique ^b,c   Rissel, Mary ^b,c   Schwarze, Per ^a   Holme, Jørn A ^a  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b INSERM   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

Author keywords

3 Aminofluoranthene; 3 Nitrofluoranthene; Apoptosis; Cell signalling; Necroptosis

Indexed keywords

3 AMINOFLUORANTHENE; 3 NITROFLUORANTHENE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AMINO ACID DECARBOXYLASE; BENZYLOXYCARBONYLVALYLALANYLASPARTYLFLUOROMETHYLKETONE; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOHEXIMIDE; CYTOCHROME P450 1A1; FLUORANTHENE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE SYNTHASE; PROPIDIUM IODIDE; PROTEIN INHIBITOR; PROTEIN NEC 1; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL PROLIFERATION; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME METABOLISM; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; FLUORENES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MITOGEN-ACTIVATED PROTEIN KINASES; NECROSIS;

EID: 58149156276     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.10.021     Document Type: Article

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