Plasma phospholipid polyunsaturated fatty acids and homocysteine in Chinese type 2 diabetes patients

Asia Pacific Journal of Clinical Nutrition

Volumn 21, Issue 3, 2012, Pages 394-399

  Huang, Tao ^a,b   Asimi, Sailimuhan ^a,b   Lou, Dajun ^c   Li, Duo ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b APCNS Centre of Nutrition and Food Safety   (China)

^c Shaoxing Hospital   (China)

Author keywords

Homocysteine; Monounsaturated fatty acids; n 3 polyunsaturated fatty acid; Phospholipids; Type 2 diabetes

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PHOSPHOLIPID; UNSATURATED FATTY ACID;

ADULT; AGED; ALGORITHM; ARTICLE; BLOOD; CHEMISTRY; CHINA; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; HYPERHOMOCYSTEINEMIA; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTPATIENT DEPARTMENT; PREVALENCE;

ADULT; AGED; ALGORITHMS; CHINA; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FATTY ACIDS, UNSATURATED; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; HYPERHOMOCYSTEINEMIA; MALE; MIDDLE AGED; OUTPATIENT CLINICS, HOSPITAL; PHOSPHOLIPIDS; PREVALENCE; VITAMIN B 12;

EID: 84865578325     PISSN: 09647058     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Hays NP, Galassetti PR, Coker RH. Prevention and treatment of type 2 diabetes: current role of lifestyle, natural product, and pharmacological interventions. Pharmacol Ther. 2008;118:181-91.
2. Fsadni P, Fsadni C, Fava S, Montefort S. Correlation of worldwide incidence of type 1 diabetes (Diamond) with prevalence of asthma and atopic eczema (ISAAC). Clin Respir J. 2011;6:18-25.
3. Galan P, de Bree A, Mennen L, Potier de Courcy G, Preziozi P, Bertrais S, Castetbon K, Hercberg S. Background and rationale of the SU.FOL.OM3 study: double-blind randomized placebo-controlled secondary prevention trial to test the impact of supplementation with folate, vitamin B6 and B12 and/or omega-3 fatty acids on the prevention of recurrent ischemic events in subjects with atherosclerosis in the coronary or cerebral arteries. J Nutr Health Aging. 2003;7:428-35.
4. Slatter DA, Bolton CH, Bailey AJ. The importance of lipidderived malondialdehyde in diabetes mellitus. Diabetologia. 2000;43:550-7.
5. Vollset SE, Refsum H, Tverdal A, Nygard O, Nordrehaug JE, Tell GS, Ueland PM. Plasma total homocysteine and cardiovascular and noncardiovascular mortality: the Hordaland Homocysteine Study. Am J Clin Nutr. 2001;74: 130-6.
6. Ndrepepa G, Kastrati A, Braun S, Koch W, Kolling K, Mehilli J, Schomig A. Circulating homocysteine levels in patients with type 2 diabetes mellitus. Nutr Metab Cardiovasc Dis. 2008;18:66-73.
7. Emoto M, Kanda H, Shoji T, Kawagishi T, Komatsu M, Mori K et al. Impact of insulin resistance and nephropathy on homocysteine in type 2 diabetes. Diabetes Care. 2001;24: 533-8.
8. Folsom AR, Nieto FJ, McGovern PG, Tsai MY, Malinow MR, Eckfeldt JH, Hess DL, Davis CE. Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) study. Circulation. 1998;98:204-10.
9. Mazza A, Bossone E, Mazza F, Distante A. Reduced serum homocysteine levels in type 2 diabetes. Nutr Metab Cardiovasc Dis. 2005;15:118-24.
10. De Caterina R, Madonna R, Bertolotto A, Schmidt EB. n-3 fatty acids in the treatment of diabetic patients: biological rationale and clinical data. Diabetes Care. 2007;30:1012-26.
11. Li D, Sinclair A, Wilson A, Nakkote S, Kelly F, Abedin L, Mann N, Turner A. Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men. Am J Clin Nutr. 1999;69:872-82.
12. Huang T, Wahlqvist ML, Xu T, Xu A, Zhang A, Li D. Increased plasma n-3 polyunsaturated fatty acid is associated with improved insulin sensitivity in type 2 diabetes in China. Mol Nutr Food Res. 2010;54(Suppl 1): S112-9.
13. Huang T, Bhulaidok S, Cai Z, Xu T, Xu F, Wahlqvist ML, Li D. Plasma phospholipids n-3 polyunsaturated fatty acid is associated with metabolic syndrome. Mol Nutr Food Res. 2010;54:1628-35.
14. Li D, Yu XM, Xie HB, Zhang YH, Wang Q, Zhou XQ, Yu P, Wang LJ. Platelet phospholipid n-3 PUFA negatively associated with plasma homocysteine in middle-aged and geriatric hyperlipaemia patients. Prostaglandins Leukot Essent Fatty Acids. 2007;76:293-7.
15. Li D, Mann NJ, Sinclair AJ. A significant inverse relationship between concentrations of plasma homocysteine and phospholipid docosahexaenoic acid in healthy male subjects. Lipids. 2006;41:85-9.
16. Pooya S, Jalali MD, Jazayery AD, Saedisomeolia A, Eshraghian MR, Toorang F. The efficacy of omega-3 fatty acid supplementation on plasma homocysteine and malondialdehyde levels of type 2 diabetic patients. Nutr Metab Cardiovasc Dis. 2010;20:326-31.
17. Huang T, Wahlqvist ML, Li D. Docosahexaenoic acid decreases plasma homocysteine via regulating enzyme activity and mRNA expression involved in methionine metabolism. Nutrition. 2010;26:112-9.
18. Huang T, Tucker K, Lee Y, Crott J, Parnell L, Shen J, Smith C, Ordovas J, Li D, Lai C. MAT1A variants modulate the effect of dietary fatty acids on plasma homocysteine concentrations. Nutr Metab Cardiovasc Dis. 2010; 22:362-8.
19. Huang T, Tucker KL, Lee YC, Crott JW, Parnell LD, Shen J, Smith CE, Ordovas JM, Li D, Lai CQ. Methylenetetrahydrofolate reductase variants associated with hypertension and cardiovascular disease interact with dietary polyunsaturated Fatty acids to modulate plasma homocysteine in puerto rican adults. J Nutr. 2011;141:654-9.
20. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15:539-53.
21. Vizcaino G, Diez-Ewald M, Herrmann FH, Schuster G, Torres-Guerra E, Arteaga-Vizcaino M. Homocysteinemia and its relationship with the methylentetrahydrofolate reductase polymorphism in various ethnic groups from western Venezuela. Invest Clin. 2005;46:347-55.
22. Li D, Xu T, Takase H, Tokimitsu I, Zhang P, Wang Q, Yu X, Zhang A. Diacylglycerol-induced improvement of whole-body insulin sensitivity in type 2 diabetes mellitus: a long-term randomized, double-blind controlled study. Clin Nutr. 2008;27:203-11.
23. Mann NJ, Li D, Sinclair AJ, Dudman NP, Guo XW, Elsworth GR, Wilson AK, Kelly FD. The effect of diet on plasma homocysteine concentrations in healthy male subjects. Eur J Clin Nutr. 1999;53:895-9.
24. Huang T, Yuan G, Zhang Z, Zou Z, Li D. Cardiovascular pathogenesis in hyperhomocysteinemia. Asia Pac J Clin Nutr. 2008;17:8-16.
25. Li D. Chemistry behind Vegetarianism. J Agric Food Chem. 2011;59:777-84.
26. Tessari P, Coracina A, Kiwanuka E, Vedovato M, Vettore M, Valerio A, Zaramella M, Garibotto G. Effects of insulin on methionine and homocysteine kinetics in type 2 diabetes with nephropathy. Diabetes. 2005;54(10):2968-2976.
27. Jacobs RL, House JD, Brosnan ME, Brosnan JT. Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat. Diabetes. 1998;47: 1967-70.
28. Ratnam S, Maclean KN, Jacobs RL, Brosnan ME, Kraus JP, Brosnan JT. Hormonal regulation of cystathionine betasynthase expression in liver. J Biol Chem. 2002;277:42912-8.
29. Dicker-Brown A, Fonseca VA, Fink LM, Kern PA. The effect of glucose and insulin on the activity of methylene tetrahydrofolate reductase and cystathionine-beta-synthase: studies in hepatocytes. Atherosclerosis. 2001;158:297-301.
30. Burr ML, Fehily AM, Gilbert JF, Rogers S, Holliday RM, Sweetnam PM, Elwood PC, Deadman NM. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet. 1989;2:757-61.
31. Huang T, Sinclair AJ, Shen LR, Yang B, Li D. Comparative Effects of Tuna Oil and Salmon Oil on Liver Lipid Metabolism and Fatty Acid Concentrations in Rats. Journal of Food Lipids. 2009;16:436-51.
32. Appel LJ, Miller ER, 3rd, Seidler AJ, Whelton PK. Does supplementation of diet with 'fish oil' reduce blood pressure? A meta-analysis of controlled clinical trials. Arch Int Med. 1993;153:1429-38.
33. Zeman M, Zak A, Vecka M, Tvrzicka E, Pisarikova A, Stankova B. N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination. J Nutr Biochem. 2006;17:379-84.
34. Grundt H, Nilsen DW, Mansoor MA, Hetland O, Nordoy A. Reduction in homocysteine by n-3 polyunsaturated fatty acids after 1 year in a randomised double-blind study following an acute myocardial infarction: no effect on endothelial adhesion properties. Pathophysiol Haemost Thromb. 2003;33:88-95.
35. Olszewski AJ, McCully KS. Fish oil decreases serum homocysteine in hyperlipemic men. Coron Artery Dis. 1993; 4:53-60.
36. Huang T, Zheng JS, Chen Y, Yang B, Wahlqvist ML, Li D. High consumption of n-3 polyunsaturated fatty acids decrease plasma homocysteine: a meta-analysis of randomized placebo-controlled trials. Nutrition. 2011;27: 863-7.
37. Piolot A, Blache D, Boulet L, Fortin LJ, Dubreuil D, Marcoux C, Davignon J, Lussier-Cacan S. Effect of fish oil on LDL oxidation and plasma homocysteine concentrations in health. J Lab Clin Med. 2003;141:41-9.
38. Durand P, Prost M, Loreau N, Lussier-Cacan S, Blache D. Impaired homocysteine metabolism and atherothrombotic disease. Lab Invest. 2001;81:645-72.
39. Saedisomeolia A, Wood LG, Garg ML, Gibson PG, Wark PA. Lycopene enrichment of cultured airway epithelial cells decreases the inflammation induced by rhinovirus infection and lipopolysaccharide. J Nutr Biochem. 2009;20:577-85.