Oxidative stress and glutathione response in tissue cultures from persons with major depression

Journal of Psychiatric Research

Volumn 46, Issue 10, 2012, Pages 1326-1332

  Gibson, Sara A ^a   Korade, Željka ^a,b   Shelton, Richard C ^c  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Glutathione; Glutathione reductase; Human dermal fibroblasts; Major depression; Oxidative stress; Protein carbonylation

Indexed keywords

AMITRIPTYLINE; DROSPIRENONE PLUS ETHINYLESTRADIOL; ESCITALOPRAM; EXENDIN 4; GALACTOSE; GLUCOSE; GLUTATHIONE; GLUTATHIONE REDUCTASE; HYDROCHLOROTHIAZIDE; LISINOPRIL; TOPIRAMATE; TRIAMTERENE; VENLAFAXINE; VERAPAMIL; ZIPRASIDONE;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; HUMAN; HUMAN TISSUE; MAJOR DEPRESSION; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; SKIN BIOPSY; TISSUE CULTURE; TREATMENT RESPONSE;

EID: 84865560008     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2012.06.008     Document Type: Article

References (56)

1. Akin D., Manier D.H., Sanders-Bush E., Shelton R.C. Decreased serotonin 5-HT2A receptor-stimulated phosphoinositide signaling in fibroblasts from melancholic depressed patients. Neuropsychopharmacology 2004, 29:2081-2087.
2. American Psychiatric A Diagnostic and statistical manual of mental disorders 1994, D.C., Washington. 4th ed.
3. Andreazza A.C., Kauer-Sant'anna M., Frey B.N., Bond D.J., Kapczinski F., Young L.T., et al. Oxidative stress markers in bipolar disorder: a meta-analysis. Journal of Affective Disorders 2008, 111:135-144.
4. Beavo J.A., Bechtel P.J., Krebs E.G. Activation of protein kinase by physiological concentrations of cyclic AMP. Proceedings of the National Academy of Sciences of the United States of America 1974, 71:3580-3583.
5. Beavo J.A., Bechtel P.J., Krebs E.G. Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle. Methods in Enzymology 1974, 38:299-308.
6. Calabrese V., Cornelius C., Leso V., Trovato A., Ventimiglia B., Cavallaro M., et al. Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes. Biochimica et Biophysica Acta 2011.
7. Cho S., Shin M.H., Kim Y.K., Seo J.E., Lee Y.M., Park C.H., et al. Effects of infrared radiation and heat on human skin aging in vivo. Journal of Investigative Dermatology Symposium Proceedings 2009, 14:15-19.
8. Cumurcu B.E., Ozyurt H., Etikan I., Demir S., Karlidag R. Total antioxidant capacity and total oxidant status in patients with major depression: impact of antidepressant treatment. Psychiatry and Clinical Neurosciences 2009, 63:639-645.
9. del Hoyo P., García-Redondo A., de Bustos F., Molina J.A., Sayed Y., Alonso-Navarro H., et al. Oxidative stress in skin fibroblasts cultures of patients with Huntington's disease. Neurochemical Research 2006, 31:1103-1109.
10. Dringen R. Metabolism and functions of glutathione in brain. Progress in Neurobiology 2000, 62:649-671.
11. Dringen R., Gutterer J.M., Hirrlinger J. Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. European Journal of Biochemistry 2000, 267:4912-4916.
12. Dwivedi Y., Rizavi H.S., Shukla P.K., Lyons J., Faludi G., Palkovits M., et al. Protein kinase A in postmortem brain of depressed suicide victims: altered expression of specific regulatory and catalytic subunits. Biological Psychiatry 2004, 55:234-243.
13. Fantozzi D.A., Harootunian A.T., Wen W., Taylor S.S., Feramisco J.R., Tsien R.Y., et al. Thermostable inhibitor of cAMP-dependent protein kinase enhances the rate of export of the kinase catalytic subunit from the nucleus. Journal of Biological Chemistry 1994, 269:2676-2686.
14. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured clinical interview for DSM-IV-TR axis I disorders, research version, patient edition, with psychotic screen. (SCID-I/P W/Psy SCREEN) 2009, Biometrics Research, New York Psychiatric Institute, New York, NY.
15. Floreani M., Napoli E., Martinuzzi A., Pantano G., De Riva V., Trevisan R., et al. Antioxidant defences in cybrids harboring mtDNA mutations associated with Leber's hereditary optic neuropathy. FEBS Journal 2005, 272:1124-1135.
16. Gawryluk J.W., Wang J.F., Andreazza A.C., Shao L., Young L.T. Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders. International Journal of Neuropsychopharmacology 2011, 14:123-130.
17. Giorgi C., Agnoletto C., Baldini C., Bononi A., Bonora M., Marchi S., et al. Redox control of protein kinase C: cell- and disease-specific aspects. Antioxidants & Redox Signaling 2010, 13:1051-1085.
18. Gysin R., Kraftsik R., Sandell J., Bovet P., Chappuis C., Conus P., et al. Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:16621-16626.
19. Gysin R., Riederer I.M., Cuénod M., Do K.Q., Riederer B.M. Skin fibroblast model to study an impaired glutathione synthesis: consequences of a genetic polymorphism on the proteome. Brain Research Bulletin 2009, 79:46-52.
20. Halliwell B. Reactive oxygen species in living systems: source, biochemistry, and role in human disease. American Journal of Medicine 1991, 91:14S-22S.
21. Heck D.E., Vetrano A.M., Mariano T.M., Laskin J.D. UVB light stimulates production of reactive oxygen species: unexpected role for catalase. Journal of Biological Chemistry 2003, 278:22432-22436.
22. Humphries K.M., Juliano C., Taylor S.S. Regulation of cAMP-dependent protein kinase activity by glutathionylation. Journal of Biological Chemistry 2002, 277:43505-43511.
23. Humphries K.M., Deal M.S., Taylor S.S. Enhanced dephosphorylation of cAMP-dependent protein kinase by oxidation and thiol modification. Journal of Biological Chemistry 2005, 280:2750-2758.
24. Humphries K.M., Pennypacker J.K., Taylor S.S. Redox regulation of cAMP-dependent protein kinase signaling: kinase versus phosphatase inactivation. Journal of Biological Chemistry 2007, 282:22072-22079.
25. Jeon Y.H., Heo Y.S., Kim C.M., Hyun Y.L., Lee T.G., Ro S., et al. Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development. Cellular and Molecular Life Sciences 2005, 62:1198-1220.
26. Kessler R.C., Chiu W.T., Demler O., Merikangas K.R., Walters E.E. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry 2005, 62:617-627.
27. Khanzode S.D., Dakhale G.N., Khanzode S.S., Saoji A., Palasodkar R. Oxidative damage and major depression: the potential antioxidant action of selective serotonin re-uptake inhibitors. Redox Report 2003, 8:365-370.
28. Kodydková J., Vávrová L., Zeman M., Jirák R., Macásek J., Stanková B., et al. Antioxidative enzymes and increased oxidative stress in depressive women. Clinical Biochemistry 2009, 42:1368-1374.
29. Mahadik S.P., Mukherjee S. Free radical pathology and antioxidant defense in schizophrenia: a review. Schizophrenia Research 1996, 19:1-17.
30. Manier D.H., Eiring A., Shelton R.C., Sulser F. Beta-adrenoceptor-linked protein kinase A (PKA) activity in human fibroblasts from normal subjects and from patients with major depression. Neuropsychopharmacology 1996, 15:555-561.
31. Manier D.H., Shelton R.C., Ellis T.C., Peterson C.S., Eiring A., Sulser F. Human fibroblasts as a relevant model to study signal transduction in affective disorders. Journal of Affective Disorders 2000, 61:51-58.
32. Marroquin L.D., Hynes J., Dykens J.A., Jamieson J.D., Will Y. Circumventing the Crabtree effect: replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants. Toxicological Sciences 2007, 97:539-547.
33. Meinkoth J.L., Alberts A.S., Went W., Fantozzi D., Taylor S.S., Hagiwara M., et al. Signal transduction through the cAMP-dependent protein kinase. Molecular and Cellular Biochemistry 1993, 127-128:179-186.
34. Ng F., Berk M., Dean O., Bush A.I. Oxidative stress in psychiatric disorders: evidence base and therapeutic implications. International Journal of Neuropsychopharmacology 2008, 11:851-876.
35. Oliver C.N. Inactivation of enzymes and oxidative modification of proteins by stimulated neutrophils. Archives of Biochemistry and Biophysics 1987, 253:62-72.
36. Pandey G.N., Dwivedi Y., Pandey S.C., Conley R.R., Roberts R.C., Tamminga C.A. Protein kinase C in the postmortem brain of teenage suicide victims. Neuroscience Letters 1997, 228:111-114.
37. Pandey G.N., Dwivedi Y., Kumari R., Janicak P.G. Protein kinase C in platelets of depressed patients. Biological Psychiatry 1998, 44:909-911.
38. Perera T., Lisanby S.H., Sackheim H.A. Protein kinase A in major depression: the link between hypothalamic-pituitary-adrenal axis hyperactivity and neurogenesis. CNS Spectrums 2001, 6:565-568. 571-572.
39. Perez J., Tardito D., Racagni G., Smeraldi E., Zanardi R. cAMP signaling pathway in depressed patients with psychotic features. Molecular Psychiatry 2002, 7:208-212.
40. Rahman I., Kode A., Biswas S.K. Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nature Protocols 2006, 1:3159-3165.
41. Sarandol A., Sarandol E., Eker S.S., Erdinc S., Vatansever E., Kirli S. Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative-antioxidative systems. Human Psychopharmacology 2007, 22:67-73.
42. Schmidt H.D., Shelton R.C., Duman R.S. Functional biomarkers of depression: diagnosis, treatment, and pathophysiology. Neuropsychopharmacology 2011, 36:2375-2394.
43. Schuliga M., Chouchane S., Snow E.T. Upregulation of glutathione-related genes and enzyme activities in cultured human cells by sublethal concentrations of inorganic arsenic. Toxicological Sciences 2002, 70:183-192.
44. Shelton R.C., Tomarken A.J. Can recovery from depression be achieved?. Psychiatric Services 2001, 52:1469-1478.
45. Shelton R.C., Mainer D.H., Sulser F. cAMP-dependent protein kinase activity in major depression. American Journal of Psychiatry 1996, 153:1037-1042.
46. Shelton R.C., Hal Manier D., Lewis D.A. Protein kinases A and C in post-mortem prefrontal cortex from persons with major depression and normal controls. International Journal of Neuropsychopharmacology 2009, 12:1223-1232.
47. Shelton R.C., Sanders-Bush E., Manier D.H., Lewis D.A. Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A. Neuroscience 2009, 158:1406-1415.
48. Soltaninassab S.R., Sekhar K.R., Meredith M.J., Freeman M.L. Multi-faceted regulation of gamma-glutamylcysteine synthetase. Journal of Cellular Physiology 2000, 182:163-170.
49. Stadtman E.R. Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions. Annual Review of Biochemistry 1993, 62:797-821.
50. Tabatabaie T., Floyd R.A. Susceptibility of glutathione peroxidase and glutathione reductase to oxidative damage and the protective effect of spin trapping agents. Archives of Biochemistry and Biophysics 1994, 314:112-119.
51. Taylor S.S., Knighton D.R., Zheng J., Ten Eyck L.F., Sowadski J.M. cAMP-dependent protein kinase and the protein kinase family. Faraday Discussions 1992, 143-152.
52. Teyssier J.R., Ragot S., Chauvet-Gélinier J.C., Trojak B., Bonin B. Expression of oxidative stress-response genes is not activated in the prefrontal cortex of patients with depressive disorder. Psychiatry Research 2011, 186:244-247.
53. Wen W., Harootunian A.T., Adams S.R., Feramisco J., Tsien R.Y., Meinkoth J.L., et al. Heat-stable inhibitors of cAMP-dependent protein kinase carry a nuclear export signal. Journal of Biological Chemistry 1994, 269:32214-32220.
54. Yanik M., Erel O., Kati M. The relationship between potency of oxidative stress and severity of depression. Acta Neuropsychiatrica 2004, 200-203.
55. Yumru M., Savas H.A., Kalenderoglu A., Bulut M., Celik H., Erel O. Oxidative imbalance in bipolar disorder subtypes: a comparative study. Progress in Neuropsychopharmacology & Biological Psychiatry 2009, 33:1070-1074.
56. Zafir A., Ara A., Banu N. Invivo antioxidant status: a putative target of antidepressant action. Progress in Neuropsychopharmacology & Biological Psychiatry 2009, 33:220-228.