Decreased serotonin 5-HT2A receptor-stimulated phosphoinositide signalling in fibroblasts from melancholic deppresed patients

Neuropsychopharmacology

Volumn 29, Issue 11, 2004, Pages 2081-2087

  Akin, Demet ^a   Manier, D Hal ^a   Sanders Bush, Elaine ^a   Shelton, Richard C ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

5 HT2A; Depression; Fibroblast; Melancholia; Phosphatidylinositol; Phosphoinositide; Receptors; Serotonin

Indexed keywords

1 ALPHA LYSOPHOSPHATIDIC ACID; BRADYKININ; LYSERGIDE; LYSOPHOSPHATIDIC ACID; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPASE C; PHOSPHOLIPASE C BETA1; PROTEIN; PROTEIN GALPHAQ11; PROTEIN GQ; SEROTONIN 2A RECEPTOR; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPRESSION; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HYDROLYSIS; MALE; MELANCHOLIA; MOOD DISORDER; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADULT; AGED; CELLS, CULTURED; DEPRESSIVE DISORDER; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FIBROBLASTS; HUMANS; MALE; MIDDLE AGED; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN; SIGNAL TRANSDUCTION;

EID: 8444238234     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300505     Document Type: Article

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