Human fibroblasts as a relevant model to study signal transduction in affective disorders

Journal of Affective Disorders

Volumn 61, Issue 1-2, 2000, Pages 51-58

  Manier, D H ^a   Shelton, R C ^a   Ellis, T C ^a   Peterson, C S ^a   Eiring, A ^a   Sulser, F ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Beta adrenoceptors; CREB P; Cyclic AMP; Human fibroblasts; Isoproterenol; Luciferase activity; Major depression; Protein kinase A (PKA)

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ISOPRENALINE; LUCIFERASE;

AFFECTIVE NEUROSIS; ARTICLE; CONTROLLED STUDY; DEPRESSION; ENZYME SUBUNIT; FIBROBLAST; GENE ACTIVATION; GENE AMPLIFICATION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; REPORTER GENE; SIGNAL TRANSDUCTION;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEPRESSIVE DISORDER, MAJOR; FIBROBLASTS; GENE EXPRESSION; GENES, REPORTER; HUMANS; ISOPROTERENOL; LUCIFERASES; PHOSPHORYLATION; PROPANOLAMINES; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 0034545421     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0327(99)00190-1     Document Type: Article

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