Generation of carbon monoxide releasing molecules (CO-RMs) as drug candidates for the treatment of acute liver injury: Targeting of CO-RMs to the liver

Organometallics

Volumn 31, Issue 16, 2012, Pages 5810-5822

  Marques, Ana R ^a,d   Kromer, Lukas ^b   Gallo, David J ^a,d   Penacho, Nuno ^a,d   Rodrigues, Sandra S ^a,d   Seixas, João D ^a,b,e   Bernardes, Gonçalo J L ^a,d,e   Reis, Patrícia M ^a,b,d   Otterbein, Sherrie L ^a,d   Ruggieri, Rachel A ^a,d   Gonçalves, Ana S G ^a,d   Gonçalves, Ana M L ^a,d   Matos, Marta N De ^a,d   Bento, Isabel ^b   Otterbein, Leo E ^a,c,d   Blättler, Walter A ^a,d   Romão, Carlos C ^a,b,d  

^a Alfama Inc   (Portugal)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c HARVARD MEDICAL SCHOOL   (United States)

^d 100 Cummings Center ^*  (United States)

^e ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LIVER FAILURE; ACUTE LIVER INJURY; BINDING AFFINITIES; BIOLOGICAL EFFECTS; CARBONYL COMPLEXES; CARRIER MOLECULES; DRUG CANDIDATES; IN-VIVO; LOW TOXICITY; NATURAL CO; THERAPEUTIC AGENTS;

BINDING ENERGY; CARBON DIOXIDE; CARBON MONOXIDE; CHEMICAL COMPOUNDS; HEMOGLOBIN; HISTOLOGY; MOLYBDENUM; ORGANOMETALLICS; TISSUE;

MOLECULES;

EID: 84865520405     PISSN: 02767333     EISSN: 15206041     Source Type: Journal    
DOI: 10.1021/om300360c     Document Type: Article

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