An inhibitor of phospholipase A 2 group IIA modulates adipocyte signaling and protects against diet-induced metabolic syndrome in rats

Diabetes

Volumn 61, Issue 9, 2012, Pages 2320-2329

  Iyer, Abishek ^a   Lim, Junxian ^a   Poudyal, Hemant ^a   Reid, Robert C ^a   Suen, Jacky Y ^a   Webster, Julie ^b   Prins, Johannes B ^b   Whitehead, Jonathan P ^b   Fairlie, David P ^a   Brown, Lindsay ^a,c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b MATER MEDICAL RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF SOUTHERN QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

5 (4 BENZYLOXYPHENYL)(PHENYLHEPTANOYLAMINO)PENTANOIC ACID; ANTIOBESITY AGENT; CARBOHYDRATE; KH 064; LIPOPOLYSACCHARIDE; MESSENGER RNA; PALMITIC ACID; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 GROUP II; PHOSPHOLIPASE A2 GROUP IIA; PHOSPHOLIPASE A2 INHIBITOR; PROSTAGLANDIN E2; SATURATED FATTY ACID; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE; 5 (4 BENZYLOXYPHENYL) 4S (7 PHENYLHEPTANOYLAMINO)PENTANOIC ACID; 5-(4-BENZYLOXYPHENYL)-4S-(7-PHENYLHEPTANOYLAMINO)PENTANOIC ACID; CALCIUM INDEPENDENT PHOSPHOLIPASE A2; PLA2G16 PROTEIN, RAT; PLA2G2A PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CARDIOVASCULAR DISEASE; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; ENZYME RELEASE; GENE; GLUCOSE INTOLERANCE; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; INSULIN SENSITIVITY; INTRAABDOMINAL FAT; INTRACELLULAR SIGNALING; LIPID DIET; LIPOLYSIS; MACROPHAGE; METABOLIC SYNDROME X; NONHUMAN; OBESITY; PLA2G2A GENE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG ANTAGONISM; INSULIN RESISTANCE; MALE; MAST CELL; MONOCYTE; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION (PROCESS); SIGNAL TRANSDUCTION; T LYMPHOCYTE; WISTAR RAT;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; CELL LINE; DIET, HIGH-FAT; DINOPROSTONE; GLUCOSE INTOLERANCE; GROUP II PHOSPHOLIPASES A2; HUMANS; INSULIN RESISTANCE; LIPOLYSIS; MACROPHAGES; MALE; MAST CELLS; METABOLIC SYNDROME X; MICE; MONOCYTES; OBESITY; PENTANOIC ACIDS; PHOSPHOLIPASES A2, CALCIUM-INDEPENDENT; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR SUPPRESSOR PROTEINS;

EID: 84865512175     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-1179     Document Type: Article

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