-
1
-
-
84864167974
-
-
Genentech. AVASTIN prescribing information (6 January, date last accessed)
-
Genentech. AVASTIN prescribing information. http://www.gene.com/gene/products/information/pdf/avastin-prescribing.pdf (6 January 2010, date last accessed).
-
(2010)
-
-
-
2
-
-
84864170664
-
-
National Cancer Institute, US National Institutes of Health.(6 January, date last accessed)
-
National Cancer Institute, US National Institutes of Health. http://www.cancer.gov/clinicaltrials/search (6 January 2009, date last accessed).
-
(2009)
-
-
-
3
-
-
0042887615
-
An overview of targeted treatments in cancer
-
Abou-Jawde R, Choueiri T, Alemany C, Mekhail T. An overview of targeted treatments in cancer. Clin Ther 2003; 25(8): 2121-2137.
-
(2003)
Clin Ther
, vol.25
, Issue.8
, pp. 2121-2137
-
-
Abou-Jawde, R.1
Choueiri, T.2
Alemany, C.3
Mekhail, T.4
-
4
-
-
34548141828
-
Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab
-
Scappaticci FA, Skillings JR, Holden SN, et al. Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab. J Natl Cancer Inst 2007; 99(16): 1232-1239.
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.16
, pp. 1232-1239
-
-
Scappaticci, F.A.1
Skillings, J.R.2
Holden, S.N.3
-
5
-
-
77951269420
-
Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis of randomized controlled trials
-
Ranpura V, Hapani S, Chuang J, Wu S. Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis of randomized controlled trials. Acta Oncol 2010; 49(3): 287-297.
-
(2010)
Acta Oncol
, vol.49
, Issue.3
, pp. 287-297
-
-
Ranpura, V.1
Hapani, S.2
Chuang, J.3
Wu, S.4
-
6
-
-
42549099895
-
CONSORT for reporting randomised trials in journal and conference abstracts
-
Hopewell S, Clarke M, Moher D, et al. CONSORT for reporting randomised trials in journal and conference abstracts. Lancet 2008; 371(9609): 281-283.
-
(2008)
Lancet
, vol.371
, Issue.9609
, pp. 281-283
-
-
Hopewell, S.1
Clarke, M.2
Moher, D.3
-
7
-
-
0022992740
-
Meta-analysis in clinical trials
-
DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7(3): 177-188.
-
(1986)
Control Clin Trials
, vol.7
, Issue.3
, pp. 177-188
-
-
DerSimonian, R.1
Laird, N.2
-
8
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003; 327(7414): 557-560.
-
(2003)
BMJ
, vol.327
, Issue.7414
, pp. 557-560
-
-
Higgins, J.P.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
9
-
-
0028659004
-
Operating characteristics of a rank correlation test for publication bias
-
Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50(4): 1088-1101.
-
(1994)
Biometrics
, vol.50
, Issue.4
, pp. 1088-1101
-
-
Begg, C.B.1
Mazumdar, M.2
-
10
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315(7109): 629-634.
-
(1997)
BMJ
, vol.315
, Issue.7109
, pp. 629-634
-
-
Egger, M.1
Davey Smith, G.2
Schneider, M.3
Minder, C.4
-
11
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial
-
Escudier B, Pluzanska A, Koralewski P, et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007; 370(9605): 2103-2111.
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
-
12
-
-
66149147757
-
Initial safety report of NSABP C-08: a randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer
-
Allegra CJ, Yothers G, O'Connell MJ, et al. Initial safety report of NSABP C-08: a randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer. J Clin Oncol 2009; 27(20): 3385-3390.
-
(2009)
J Clin Oncol
, vol.27
, Issue.20
, pp. 3385-3390
-
-
Allegra, C.J.1
Yothers, G.2
O'Connell, M.J.3
-
13
-
-
62449124416
-
Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil
-
Reck M, von Pawel J, Zatloukal P, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol 2009; 27(8): 1227-1234.
-
(2009)
J Clin Oncol
, vol.27
, Issue.8
, pp. 1227-1234
-
-
Reck, M.1
von Pawel, J.2
Zatloukal, P.3
-
14
-
-
56749161699
-
Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206
-
Rini BI, Halabi S, Rosenberg JE, et al. Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206. J Clin Oncol 2008; 26(33): 5422-5428.
-
(2008)
J Clin Oncol
, vol.26
, Issue.33
, pp. 5422-5428
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
-
15
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study
-
Saltz LB, Clarke S, Diaz-Rubio E, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008; 26(12): 2013-2019.
-
(2008)
J Clin Oncol
, vol.26
, Issue.12
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
-
16
-
-
34248173883
-
Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200
-
Giantonio BJ, Catalano PJ, Meropol NJ, et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 2007; 25(12): 1539-1544.
-
(2007)
J Clin Oncol
, vol.25
, Issue.12
, pp. 1539-1544
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
-
17
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350(23): 2335-2342.
-
(2004)
N Engl J Med
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
18
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007; 357(26): 2666-2676.
-
(2007)
N Engl J Med
, vol.357
, Issue.26
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
19
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
Miller KD, Chap LI, Holmes FA, et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 2005; 23(4): 792-799.
-
(2005)
J Clin Oncol
, vol.23
, Issue.4
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
-
20
-
-
65549150854
-
Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer
-
Van Cutsem E, Vervenne WL, Bennouna J, et al. Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer. J Clin Oncol 2009; 27(13): 2231-2237.
-
(2009)
J Clin Oncol
, vol.27
, Issue.13
, pp. 2231-2237
-
-
Van Cutsem, E.1
Vervenne, W.L.2
Bennouna, J.3
-
21
-
-
0037208589
-
Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
-
Kabbinavar F, Hurwitz HI, Fehrenbacher L, et al. Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003; 21(1): 60-65.
-
(2003)
J Clin Oncol
, vol.21
, Issue.1
, pp. 60-65
-
-
Kabbinavar, F.1
Hurwitz, H.I.2
Fehrenbacher, L.3
-
22
-
-
20544478429
-
Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial
-
Kabbinavar FF, Schulz J, McCleod M, et al. Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial. J Clin Oncol 2005; 23(16): 3697-3705.
-
(2005)
J Clin Oncol
, vol.23
, Issue.16
, pp. 3697-3705
-
-
Kabbinavar, F.F.1
Schulz, J.2
McCleod, M.3
-
23
-
-
36048982143
-
Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non small-cell lung cancer
-
Herbst RS, O'Neill VJ, Fehrenbacher L, et al. Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non small-cell lung cancer. J Clin Oncol 2007; 25(30): 4743-4750.
-
(2007)
J Clin Oncol
, vol.25
, Issue.30
, pp. 4743-4750
-
-
Herbst, R.S.1
O'Neill, V.J.2
Fehrenbacher, L.3
-
24
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-smallcell lung cancer
-
Johnson DH, Fehrenbacher L, Novotny WF, et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-smallcell lung cancer. J Clin Oncol 2004; 22(11): 2184-2191.
-
(2004)
J Clin Oncol
, vol.22
, Issue.11
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
25
-
-
59249096067
-
Capecitabine and irinotecan with and without bevacizumab for advanced colorectal cancer patients
-
Moehler M, Sprinzl MF, Abdelfattah M, et al. Capecitabine and irinotecan with and without bevacizumab for advanced colorectal cancer patients. World J Gastroenterol 2009; 15(4): 449-456.
-
(2009)
World J Gastroenterol
, vol.15
, Issue.4
, pp. 449-456
-
-
Moehler, M.1
Sprinzl, M.F.2
Abdelfattah, M.3
-
26
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006; 355(24): 2542-2550.
-
(2006)
N Engl J Med
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
27
-
-
66149133167
-
International multi-centre randomised Phase II/III study of capecitabine (Cap), bevacizumab (Bev) and mitomycin C (MMC) as first-line treatment for metastatic colorectal cancer (mCRC): final safety analysis of the AGITG MAX trial
-
Price T, Gebski V, van Hazel G, et al. International multi-centre randomised Phase II/III study of capecitabine (Cap), bevacizumab (Bev) and mitomycin C (MMC) as first-line treatment for metastatic colorectal cancer (mCRC): final safety analysis of the AGITG MAX trial. Proc Am Soc Clin Oncol 2008; 26 (15 Suppl): 4029.
-
(2008)
Proc Am Soc Clin Oncol
, vol.26
, Issue.15 SUPPL.
, pp. 4029
-
-
Price, T.1
Gebski, V.2
van Hazel, G.3
-
28
-
-
54249120945
-
Randomized, double-blind, placebo-controlled, phase III study of bevacizumab with docetaxel or docetaxel with placebo as firstline therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO
-
abs
-
Miles D, Chan A, Romieu G, et al. Randomized, double-blind, placebo-controlled, phase III study of bevacizumab with docetaxel or docetaxel with placebo as firstline therapy for patients with locally recurrent or metastatic breast cancer (mBC): AVADO. Proc Am Soc Clin Oncol 2008; 26 (15 Suppl): abs LBA1011.
-
(2008)
Proc Am Soc Clin Oncol
, vol.26
, Issue.15 SUPPL.
-
-
Miles, D.1
Chan, A.2
Romieu, G.3
-
29
-
-
35548941394
-
A double-blind, placebo-controlled, randomized phase III trial of gemcitabine (G) plus bevacizumab (B) versus gemcitabine plus placebo (P) in patients (pts) with advanced pancreatic cancer (PC): a preliminary analysis of Cancer and Leukemia Group B (CALGB)
-
Kindler H, Niedzwiecki D, Hollis D, et al. A double-blind, placebo-controlled, randomized phase III trial of gemcitabine (G) plus bevacizumab (B) versus gemcitabine plus placebo (P) in patients (pts) with advanced pancreatic cancer (PC): a preliminary analysis of Cancer and Leukemia Group B (CALGB). Proc Am Soc Clin Oncol 2007; 25 (18 Suppl): 4508.
-
(2007)
Proc Am Soc Clin Oncol
, vol.25
, Issue.18 SUPPL.
, pp. 4508
-
-
Kindler, H.1
Niedzwiecki, D.2
Hollis, D.3
-
30
-
-
40749158416
-
Final analysis of a multi-center, double-blind, placebo-controlled, randomized phase II trial of gemcitabine/ cisplatin (GC) plus bevacizumab (B) or placebo (P) in patients (pts) with malignant mesothelioma (MM)
-
Karrison T, Kindler H, Gandara D, et al. Final analysis of a multi-center, double-blind, placebo-controlled, randomized phase II trial of gemcitabine/ cisplatin (GC) plus bevacizumab (B) or placebo (P) in patients (pts) with malignant mesothelioma (MM). Proc Am Soc Clin Oncol 2007; 25 (18 Suppl): 7526.
-
(2007)
Proc Am Soc Clin Oncol
, vol.25
, Issue.18 SUPPL.
, pp. 7526
-
-
Karrison, T.1
Kindler, H.2
Gandara, D.3
-
31
-
-
57049112847
-
Gemcitabine: vascular toxicity and prothrombotic potential
-
Dasanu CA. Gemcitabine: vascular toxicity and prothrombotic potential. Expert Opin Drug Saf 2008; 7(6): 703-716.
-
(2008)
Expert Opin Drug Saf
, vol.7
, Issue.6
, pp. 703-716
-
-
Dasanu, C.A.1
-
32
-
-
66949158016
-
Fluoropyrimidine-associated cardiotoxicity: revisited
-
Saif MW, Shah MM, Shah AR. Fluoropyrimidine-associated cardiotoxicity: revisited. Expert Opin Drug Saf 2009; 8(2): 191-202.
-
(2009)
Expert Opin Drug Saf
, vol.8
, Issue.2
, pp. 191-202
-
-
Saif, M.W.1
Shah, M.M.2
Shah, A.R.3
-
33
-
-
0034111118
-
Thromboembolic events during chemotherapy for germ cell cancer: a cohort study and review of the literature
-
Weijl NI, Rutten MF, Zwinderman AH, et al. Thromboembolic events during chemotherapy for germ cell cancer: a cohort study and review of the literature. J Clin Oncol 2000; 18(10): 2169-2178.
-
(2000)
J Clin Oncol
, vol.18
, Issue.10
, pp. 2169-2178
-
-
Weijl, N.I.1
Rutten, M.F.2
Zwinderman, A.H.3
-
34
-
-
52649099592
-
Cisplatin-associated thrombosis
-
Jafri M, Protheroe A. Cisplatin-associated thrombosis. Anticancer Drugs 2008; 19(9): 927-929.
-
(2008)
Anticancer Drugs
, vol.19
, Issue.9
, pp. 927-929
-
-
Jafri, M.1
Protheroe, A.2
-
35
-
-
0026026353
-
Cardiotoxicity of interferon. A review of 44 cases
-
Sonnenblick M, Rosin A. Cardiotoxicity of interferon. A review of 44 cases. Chest 1991; 99(3): 557-561.
-
(1991)
Chest
, vol.99
, Issue.3
, pp. 557-561
-
-
Sonnenblick, M.1
Rosin, A.2
-
36
-
-
75649143725
-
Targeted therapies: sunitinib in RCC-expanded access equals expanded benefit?
-
Choueiri TK, Atkins MB. Targeted therapies: sunitinib in RCC-expanded access equals expanded benefit? Nat Rev Clin Oncol 2009; 6(12): 679-680.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, Issue.12
, pp. 679-680
-
-
Choueiri, T.K.1
Atkins, M.B.2
-
37
-
-
70350743324
-
Diagnosis and initial treatment of venous thromboembolism in patients with cancer
-
Streiff MB. Diagnosis and initial treatment of venous thromboembolism in patients with cancer. J Clin Oncol 2009; 27(29): 4889-4894.
-
(2009)
J Clin Oncol
, vol.27
, Issue.29
, pp. 4889-4894
-
-
Streiff, M.B.1
-
38
-
-
0036910386
-
The role of hydrogen peroxide in endothelial proliferative responses
-
Stone JR, Collins T. The role of hydrogen peroxide in endothelial proliferative responses. Endothelium 2002; 9(4): 231-238.
-
(2002)
Endothelium
, vol.9
, Issue.4
, pp. 231-238
-
-
Stone, J.R.1
Collins, T.2
-
39
-
-
0035895711
-
Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
-
Zachary I, Gliki G. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc Res 2001; 49(3): 568-581.
-
(2001)
Cardiovasc Res
, vol.49
, Issue.3
, pp. 568-581
-
-
Zachary, I.1
Gliki, G.2
-
40
-
-
33748429741
-
Mechanisms of endothelial response to oxidative aggression: protective role of autologous VEGF and induction of VEGFR2 by H2O2
-
Gonzalez-Pacheco FR, Deudero JJ, Castellanos MC, et al. Mechanisms of endothelial response to oxidative aggression: protective role of autologous VEGF and induction of VEGFR2 by H2O2. Am J Physiol Heart Circ Physiol 2006; 291(3): H1395-H1401.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
, Issue.3
-
-
Gonzalez-Pacheco, F.R.1
Deudero, J.J.2
Castellanos, M.C.3
-
41
-
-
34250365240
-
Mechanisms of adverse effects of anti-VEGF therapy for cancer
-
Kamba T, McDonald DM. Mechanisms of adverse effects of anti-VEGF therapy for cancer. Br J Cancer 2007; 96(12): 1788-1795.
-
(2007)
Br J Cancer
, vol.96
, Issue.12
, pp. 1788-1795
-
-
Kamba, T.1
McDonald, D.M.2
-
42
-
-
57749207937
-
Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice
-
Meyer T, Robles-Carrillo L, Robson T, et al. Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice. J Thromb Haemost 2009; 7(1): 171-181.
-
(2009)
J Thromb Haemost
, vol.7
, Issue.1
, pp. 171-181
-
-
Meyer, T.1
Robles-Carrillo, L.2
Robson, T.3
|