Conjugation of catechols by recombinant human sulfotransferases, UDP-glucuronosyltransferases, and soluble catechol O-methyltransferase: Structure-conjugation relationships and predictive models

Drug Metabolism and Disposition

Volumn 31, Issue 9, 2003, Pages 1187-1197

  Taskinen, Jyrki ^a   Ethell, Brian T ^b   Pihlavisto, Pia ^a,c   Hood, Alan M ^b   Burchell, Brian ^b   Coughtrie, Michael W H ^b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c ORION CORPORATION   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYESTRADIOL; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 3,5 DINITROCATECHOL; 6 HYDROXYDOPA; ADRENALIN; APOMORPHINE; CARBIDOPA; CATECHIN; CATECHOL DERIVATIVE; CATECHOL METHYLTRANSFERASE; CHLOROGENIC ACID; COMPLEMENTARY DNA; DIHYDREXIDINE; DOBUTAMINE; DOPAMINE; ENTACAPONE; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; GALLIC ACID; GLUCURONOSYLTRANSFERASE; LEVODOPA; NATURAL PRODUCT; NORADRENALIN; RECOMBINANT ENZYME; ROSMARINIC ACID; SULFOTRANSFERASE; TOLCAPONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; DRUG CONJUGATION; DRUG METABOLISM; ENZYME ASSAY; ESCHERICHIA COLI; HUMAN; IN VITRO STUDY; MODEL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

CATECHOL O-METHYLTRANSFERASE; CATECHOLS; GLUCURONOSYLTRANSFERASE; HUMANS; MODELS, MOLECULAR; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SULFOTRANSFERASES;

ANIMALIA; ESCHERICHIA COLI;

EID: 0042858525     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.31.9.1187     Document Type: Article

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