Connexin 43, angiotensin II, endothelin 1, and type III collagen alterations in heart of rats having undergone fatal electrocution

American Journal of Forensic Medicine and Pathology

Volumn 33, Issue 3, 2012, Pages 215-221

  Huang, Quan Yong ^a,b   Chen, Yu Chuan ^a   Liu, Shui Ping ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b DALI UNIVERSITY   (China)

Author keywords

angiotensin II; connexin 43; electrocution; endothelin 1; type III collagen

Indexed keywords

ANGIOTENSIN II; COLLAGEN TYPE 3; ENDOTHELIN 1;

ANIMAL; ARTICLE; ELECTRIC INJURY; FORENSIC PATHOLOGY; HEART MUSCLE; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; MICROSCOPY; RAT; SPRAGUE DAWLEY RAT;

ANGIOTENSIN II; ANIMALS; COLLAGEN TYPE III; ELECTRIC INJURIES; ENDOTHELIN-1; FORENSIC PATHOLOGY; IMMUNOHISTOCHEMISTRY; MICROSCOPY; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84865499433     PISSN: 01957910     EISSN: None     Source Type: Journal    
DOI: 10.1097/PAF.0b013e31823f04eb     Document Type: Article

References (53)

1. Spies C, Trohman RG. Narrative review: electrocution and life-threatening electrical injuries. Ann Intern Med. 2006; 145:531-537.
2. Wick R, Gilbert JD, Simpson E, et al. Fatal electrocution in adultsVa 30-year study. Med Sci Law. 2006;46:166-172.
3. Wankhede AG, Sariya DR. An electrocution by metal kite line. Forensic Sci Int. 2006;163:141-143.
4. Pfeiffer H, Du Chesne A, Brinkmann B. An unusual case of homicidal near drowning followed by electrocution. Int J Legal Med. 2006;120:36-41.
5. Laupland KB, Kortbeek JB, Findlay C, et al. Population-based study of severe trauma due to electrocution in the Calgary Health Region, 1996-2002. Can J Surg. 2005;48:289-292.
6. Bligh-Glover WZ, Miller FP, Balraj EK. Two cases of suicidal electrocution. Am J Forensic Med Pathol. 2004;25:255-258.
7. Schott JC, Davis GJ, Hunsaker Jr. Accidental electrocution during autoeroticism: a shocking case. Am J Forensic Med Pathol. 2003;24:92-95.
8. di Nunno N, Vimercati L, Viola L, et al. A case of electrocution during illegal fishing activities. Am J Forensic Med Pathol. 2003;24:164-167.
9. James TN, Riddick L, Embry JH. Cardiac abnormalities demonstrated postmortem in four cases of accidental electrocution and their potential significance relative to nonfatal electrical injuries of the heart. Am Heart J. 1990;120:143-157.
10. Karger B, Suggeler O, Brinkmann B. ElectrocutionVautopsy study with emphasis on "electrical petechiae." Forensic Sci Int. 2002;126:210-213.
11. Wang Y, Liu M, Cheng WB, et al. Endothelial cell membrane perforation of aorta and pulmonary artery in the electrocution victims. Forensic Sci Int. 2008;178:204-206.
12. Chen X, Zhang Y. Myocardial Cx43 expression in the cases of sudden death due to dilated cardiomyopathy. Forensic Sci Int. 2006;162:170-173.
13. Kvakan H, Kleinewietfeld M, Qadri F, et al. Regulatory T cells ameliorate angiotensin IIYinduced cardiac damage. Circulation. 2009;119:2904-2912.
14. Iemitsu M, Maeda S, Otsuki T, et al. Time course alterations of myocardial endothelin-1 production during the formation of exercise training-induced cardiac hypertrophy. Exp Biol Med (Maywood). 2006;231:871-875.
15. Papassotiriou J, Morgenthaler NG, Struck J, et al. Immunoluminometric assay for measurement of the C-terminal endothelin-1 precursor fragment in human plasma. Clin Chem. 2006;52:1144-1151.
16. Terui G, Goto T, Katsuta M, et al. Effect of pioglitazone on left ventricular diastolic function and fibrosis of type III collagen in type 2 diabetic patients. J Cardiol. 2009;54:52-58.
17. Smith PS, Parkinson IH, Leong AS. Principles of ploidy analysis by static cytometry. Clin Mol Pathol. 1996;49:M104-M111.
18. Dong J, Yin H, Liu W, et al. Congenital iodine deficiency and hypothyroidism impair LTP and decrease C-fos and C-jun expression in rat hippocampus. Neurotoxicology. 2005;26:417-426.
19. van Kuijk AW, Gerlag DM, Vos K, et al. A prospective, randomised, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: effects of adalimumab treatment on synovial tissue. Ann Rheum Dis. 2009;68:1303-1309.
20. Klintschar M, Grabuschnigg P, Beham A. Death from electrocution during autoerotic practice: case report and review of the literature. Am J Forensic Med Pathol. 1998;19:190-193.
21. Wright RK. Death or injury caused by electrocution. Clin Lab Med. 1983;3:343-353.
22. Zhang P, Cai S. Study on electrocution death by low-voltage. Forensic Sci Int. 1995;76:115-119.
23. Marc B, Baudry F, Douceron H, et al. Suicide by electrocution with low-voltage current. J Forensic Sci. 2000;45:216-222.
24. Leung DS, Unsicker K, Reuss B. Expression and developmental regulation of gap junction connexins Cx26, Cx32, Cx43 and Cx45 in the rat midbrain-floor. Int J Dev Neurosci. 2002; 20:63-75.
25. Herve JC, Plaisance I, Loncarek J, et al. Is the junctional uncoupling elicited in rat ventricular myocytes by some dephosphorylation treatments due to changes in the phosphorylation status of Cx43? Eur Biophys J. 2004;33:201-210.
26. Simek J, Churko J, Shao Q, et al. Cx43 has distinct mobility within plasma-membrane domains, indicative of progressive formation of gap-junction plaques. J Cell Sci. 2009;122:554-562.
27. Hernandez M, Shao Q, Yang XJ, et al. A histone deacetylationYdependent mechanism for transcriptional repression of the gap junction gene Cx43 in prostate cancer cells. Prostate. 2006;66:1151-1161.
28. Moorby C, Patel M. Dual functions for connexins: Cx43 regulates growth independently of gap junction formation. Exp Cell Res. 2001;271:238-248.
29. Derangeon M, Bourmeyster N, Plaisance I, et al. RhoA GTPase and F-actin dynamically regulate the permeability of Cx43-made channels in rat cardiac myocytes. J Biol Chem. 2008;283:30754-30765.
30. Lerner DL, Yamada KA, Schuessler RB, et al. Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice. Circulation. 2000;101:547-552.
31. Bras-Silva C, Leite-Moreira AF. Myocardial effects of endothelin-1. Rev Port Cardiol. 2008;27:925-951.
32. Benigni A, Corna D, Zoja C, et al. Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest. 2009;119:524-530.
33. Makkar KM, Sanoski CA, Spinler SA. Role of angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and aldosterone antagonists in the prevention of atrial and ventricular arrhythmias. Pharmacotherapy. 2009;29:31-48.
34. + pump via PKC-dependent activation of NADPH oxidase. Am J Physiol Cell Physiol. 2009;296:C693-C700.
35. Gao X, He X, Luo B, et al. Angiotensin II increases collagen I expression via transforming growth factor-betal and extracellular signalYregulated kinase in cardiac fibroblasts. Eur J Pharmacol. 2009;606:115-120.
36. Porrello ER, D'Amore A, Curl CL, et al. Angiotensin II type 2 receptor antagonizes angiotensin II type 1 receptorYmediated cardiomyocyte autophagy. Hypertension. 2009;53:1032-1040.
37. Penicka M, Gregor P, Kerekes R, et al. The effects of candesartan on left ventricular hypertrophy and function in nonobstructive hypertrophic cardiomyopathy: a pilot, randomized study. J Mol Diagn. 2009; 11:35-41.
38. Gujic M, Houssiere A, Xhaet O, et al. Does endothelin play a role in chemoreception during acute hypoxia in normal men? Chest. 2007;131:1467-1472.
39. Chung KY, Walker JW. Interaction and inhibitory cross-talk between endothelin and ErbB receptors in the adult heart. Mol Pharmacol. 2007;71:1494-1502.
40. Isaka M, Kudo A, Imamura M, et al. Endothelin receptors, localized in sympathetic nerve terminals of the heart, modulate norepinephrine release and reperfusion arrhythmias. Basic Res Cardiol. 2007;102: 154-162.
41. Toma I, Nagy A, Janosi C, et al. Effects of intrapericardially administered endothelin-1 on pericardial natriuretic peptide concentrations of the in situ dog heart. J Cardiovasc Pharmacol. 2004;44(suppl 1):S231-S233.
42. Nishimaru K, Arimoto T, Takeishi Y, et al. Overexpression of diacylglycerol kinase zeta inhibits endothelin-1-induced decreases in Ca2+ transients and cell shortening in mouse ventricular myocytes. J Mol Cell Cardiol. 2008;44:520-526.
43. Udyavar AR, Chen YC, Chen YJ, et al. Endothelin-1 modulates the arrhythmogenic activity of pulmonary veins. J Cardiovasc Electrophysiol. 2008;19:285-292.
44. Zeng Q, Zhou Q, Yao F, et al. Endothelin-1 regulates cardiac L-type calcium channels via NAD(P)H oxidase-derived superoxide. J Pharmacol Exp Ther. 2008;326:732-738.
45. Ogata T, Miyauchi T, Irukayama-Tomobe Y, et al. The peroxisome proliferatorYactivated receptor alpha activator fenofibrate inhibits endothelin-1-induced cardiac fibroblast proliferation. J Cardiovasc Pharmacol. 2004;44(suppl 1):S279-S282.
46. Gramann M, Wendler O, Haeberle L, et al. Expression of collagen types I, II and III in juvenile angiofibromas. Cells Tissues Organs. 2009;189:403-409.
47. Tateya T, Tateya I, Bless DM. Immuno-scanning electron microscopy of collagen types I and III in human vocal fold lamina propria. Ann Otol Rhinol Laryngol. 2007;116:156-159.
48. Maehata Y, Takamizawa S, Ozawa S, et al. Type III collagen is essential for growth acceleration of human osteoblastic cells by ascorbic acid 2-phosphate, a long-acting vitamin C derivative. Matrix Biol. 2007;26:371-381.
49. Batra V, Musani AI, Hastie AT, et al. Bronchoalveolar lavage fluid concentrations of transforming growth factor (TGF)-beta1, TGF-beta2, interleukin (IL)-4 and IL-13 after segmental allergen challenge and their effects on alpha-smooth muscle actin and collagen III synthesis by primary human lung fibroblasts. Clin Exp Allergy. 2004;34:437-444.
50. Soufen HN, Salemi VM, Aneas IM, et al. Collagen content, but not the ratios of collagen type III/I mRNAs, differs among hypertensive, alcoholic, and idiopathic dilated cardiomyopathy. Braz J Med Biol Res. 2008;41:1098-1104.
51. Haim A, Zucker N, Levitas A, et al. Cardiac manifestations following electrocution in children. Cardiol Young. 2008;18:458-460.
52. Fischer R, Dechend R, Gapelyuk A. Angiotensin II-induced sudden arrhythmic death and electrical remodeling. Am J Physiol Heart Circ Physiol. 2007;293:H1242-H1253.
53. Huang QY, Chen YC, Liu SP. Reduction in Purkinje fiber number in rats undergone fatal electrocution [published online ahead of print June 25, 2010]. Am J Forensic Med Pathol.