-
1
-
-
8544252411
-
Clinical strategies for expansion of hematopoietic stem cells
-
Sorrentino, B. P. (2004) Clinical strategies for expansion of hematopoietic stem cells. Nat. Rev. Immunol. 4, 878-888
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 878-888
-
-
Sorrentino, B.P.1
-
2
-
-
34547913091
-
Stem cells: A revolution in therapeutics-recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies
-
Mimeault, M., Hauke, R., and Batra, S. K. (2007) Stem cells: a revolution in therapeutics-recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. Clin. Pharmacol. Ther. 82, 252-264
-
(2007)
Clin. Pharmacol. Ther.
, vol.82
, pp. 252-264
-
-
Mimeault, M.1
Hauke, R.2
Batra, S.K.3
-
3
-
-
0035257660
-
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
-
Bhardwaj, G., Murdoch, B., Wu, D., Baker, D. P., Williams, K. P., Chadwick, K., Ling, L. E., Karanu, F. N., and Bhatia, M. (2001) Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation. Nat. Immunol. 2, 172-180
-
(2001)
Nat. Immunol.
, vol.2
, pp. 172-180
-
-
Bhardwaj, G.1
Murdoch, B.2
Wu, D.3
Baker, D.P.4
Williams, K.P.5
Chadwick, K.6
Ling, L.E.7
Karanu, F.N.8
Bhatia, M.9
-
4
-
-
0034892945
-
HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation
-
Antonchuk, J., Sauvageau, G., and Humphries, R. K. (2001) HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation. Exp. Hematol. 29, 1125-1134
-
(2001)
Exp. Hematol.
, vol.29
, pp. 1125-1134
-
-
Antonchuk, J.1
Sauvageau, G.2
Humphries, R.K.3
-
5
-
-
0037737728
-
A role for Wnt signaling in self-renewal of hematopoietic stem cells
-
Reya, T., Duncan, A. W., Ailles, L., Domen, J., Scherer, D. C., Willert, K., Hintz, L., Nusse, R., and Weissman, I. L. (2003) A role for Wnt signaling in self-renewal of hematopoietic stem cells. Nature 423, 409-414
-
(2003)
Nature
, vol.423
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
Domen, J.4
Scherer, D.C.5
Willert, K.6
Hintz, L.7
Nusse, R.8
Weissman, I.L.9
-
6
-
-
0037023528
-
HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
-
Antonchuk, J., Sauvageau, G., and Humphries, R. K. (2002) HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell 109, 39-45
-
(2002)
Cell
, vol.109
, pp. 39-45
-
-
Antonchuk, J.1
Sauvageau, G.2
Humphries, R.K.3
-
7
-
-
0033526067
-
Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells
-
Bhatia, M., Bonnet, D., Wu, D., Murdoch, B., Wrana, J., Gallacher, L., and Dick, J. E. (1999) Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J. Exp. Med. 189, 1139-1148
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1139-1148
-
-
Bhatia, M.1
Bonnet, D.2
Wu, D.3
Murdoch, B.4
Wrana, J.5
Gallacher, L.6
Dick, J.E.7
-
8
-
-
43549113659
-
Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation
-
Zhang, C. C., Kaba, M., Iizuka, S., Huynh, H., and Lodish, H. F. (2008) Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation. Blood 111, 3415-3423
-
(2008)
Blood
, vol.111
, pp. 3415-3423
-
-
Zhang, C.C.1
Kaba, M.2
Iizuka, S.3
Huynh, H.4
Lodish, H.F.5
-
9
-
-
0345708270
-
Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein
-
Amsellem, S., Pflumio, F., Bardinet, D., Izac, B., Charneau, P., Romeo, P. H., Dubart-Kupperschmitt, A., and Fichelson, S. (2003) Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein. Nat. Med. 9, 1423-1427
-
(2003)
Nat. Med.
, vol.9
, pp. 1423-1427
-
-
Amsellem, S.1
Pflumio, F.2
Bardinet, D.3
Izac, B.4
Charneau, P.5
Romeo, P.H.6
Dubart-Kupperschmitt, A.7
Fichelson, S.8
-
10
-
-
0344413639
-
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
-
Krosl, J., Austin, P., Beslu, N., Kroon, E., Humphries, R. K., and Sauvageau, G. (2003) In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat. Med. 9, 1428-1432
-
(2003)
Nat. Med.
, vol.9
, pp. 1428-1432
-
-
Krosl, J.1
Austin, P.2
Beslu, N.3
Kroon, E.4
Humphries, R.K.5
Sauvageau, G.6
-
11
-
-
41949127703
-
Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1
-
Rizo, A., Dontje, B., Vellenga, E., de Haan, G., and Schuringa, J. J. (2008) Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1. Blood 111, 2621-2630
-
(2008)
Blood
, vol.111
, pp. 2621-2630
-
-
Rizo, A.1
Dontje, B.2
Vellenga, E.3
De Haan, G.4
Schuringa, J.J.5
-
12
-
-
34247396117
-
Xom interacts with and stimulates transcriptional activity of LEF1/TCFs: Implications for ventral cell fate determination during vertebrate embryogenesis
-
Gao, H., Wu, B., Giese, R., and Zhu, Z. (2007) Xom interacts with and stimulates transcriptional activity of LEF1/TCFs: implications for ventral cell fate determination during vertebrate embryogenesis. Cell Res. 17, 345-356
-
(2007)
Cell Res.
, vol.17
, pp. 345-356
-
-
Gao, H.1
Wu, B.2
Giese, R.3
Zhu, Z.4
-
13
-
-
34247401658
-
Xomas a novel partner of LEF/TCFs during dorsal-ventral patterning of the Xenopus embryo
-
Yang, Y. (2007)Xomas a novel partner of LEF/TCFs during dorsal-ventral patterning of the Xenopus embryo. Cell Res. 17, 307-308
-
(2007)
Cell Res.
, vol.17
, pp. 307-308
-
-
Yang, Y.1
-
14
-
-
0035878478
-
Molecular cloning of a human Vent-like homeobox gene
-
Moretti, P. A., Davidson, A. J., Baker, E., Lilley, B., Zon, L. I., and D'Andrea, R. J. (2001) Molecular cloning of a human Vent-like homeobox gene. Genomics 76, 21-29
-
(2001)
Genomics
, vol.76
, pp. 21-29
-
-
Moretti, P.A.1
Davidson, A.J.2
Baker, E.3
Lilley, B.4
Zon, L.I.5
D'Andrea, R.J.6
-
15
-
-
75149190433
-
VentX, a novel lymphoid-enhancing factor/T-cell factor-associated transcription repressor, is a putative tumor suppressor
-
Gao, H., Le, Y., Wu, X., Silberstein, L. E., Giese, R. W., and Zhu, Z. (2010) VentX, a novel lymphoid-enhancing factor/T-cell factor-associated transcription repressor, is a putative tumor suppressor. Cancer Res. 70, 202-211
-
(2010)
Cancer Res.
, vol.70
, pp. 202-211
-
-
Gao, H.1
Le, Y.2
Wu, X.3
Silberstein, L.E.4
Giese, R.W.5
Zhu, Z.6
-
16
-
-
79959928611
-
The homeobox transcription factor VentX controls human macrophage terminal differentiation and proinflammatory activation
-
Wu, X., Gao, H., Ke, W., Giese, R. W., and Zhu, Z. (2011) The homeobox transcription factor VentX controls human macrophage terminal differentiation and proinflammatory activation. J. Clin. Invest. 121, 2599-2613
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2599-2613
-
-
Wu, X.1
Gao, H.2
Ke, W.3
Giese, R.W.4
Zhu, Z.5
-
17
-
-
79953320011
-
VentX transactivates p53 and p16ink4a to regulate cellular senescence
-
Wu, X., Gao, H., Ke, W., Hager, M., Xiao, S., Freeman, M. R., and Zhu, Z. (2011) VentX transactivates p53 and p16ink4a to regulate cellular senescence. J. Biol. Chem. 286, 12693-12701
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12693-12701
-
-
Wu, X.1
Gao, H.2
Ke, W.3
Hager, M.4
Xiao, S.5
Freeman, M.R.6
Zhu, Z.7
-
18
-
-
78049289467
-
The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia
-
Rawat, V. P., Arseni, N., Ahmed, F., Mulaw, M. A., Thoene, S., Heilmeier, B., Sadlon, T., D'Andrea, R. J., Hiddemann, W., Bohlander, S. K., Buske, C., and Feuring-Buske, M. (2010) The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia. Proc. Natl. Acad. Sci. U.S.A. 107, 16946-16951
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 16946-16951
-
-
Rawat, V.P.1
Arseni, N.2
Ahmed, F.3
Mulaw, M.A.4
Thoene, S.5
Heilmeier, B.6
Sadlon, T.7
D'Andrea, R.J.8
Hiddemann, W.9
Bohlander, S.K.10
Buske, C.11
Feuring-Buske, M.12
-
19
-
-
77956519710
-
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
-
Boitano, A. E., Wang, J., Romeo, R., Bouchez, L. C., Parker, A. E., Sutton, S. E., Walker, J. R., Flaveny, C. A., Perdew, G. H., Denison, M. S., Schultz, P. G., and Cooke, M. P. (2010) Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science 329, 1345-1348
-
(2010)
Science
, vol.329
, pp. 1345-1348
-
-
Boitano, A.E.1
Wang, J.2
Romeo, R.3
Bouchez, L.C.4
Parker, A.E.5
Sutton, S.E.6
Walker, J.R.7
Flaveny, C.A.8
Perdew, G.H.9
Denison, M.S.10
Schultz, P.G.11
Cooke, M.P.12
-
20
-
-
80052654597
-
Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells
-
Istvanffy, R., Kröger, M., Eckl, C., Gitzelmann, S., Vilne, B., Bock, F., Graf, S., Schiemann, M., Keller, U. B., Peschel, C., and Oostendorp, R. A. (2011) Stromal pleiotrophin regulates repopulation behavior of hematopoietic stem cells. Blood 118, 2712-2722
-
(2011)
Blood
, vol.118
, pp. 2712-2722
-
-
Istvanffy, R.1
Kröger, M.2
Eckl, C.3
Gitzelmann, S.4
Vilne, B.5
Bock, F.6
Graf, S.7
Schiemann, M.8
Keller, U.B.9
Peschel, C.10
Oostendorp, R.A.11
-
21
-
-
79951832932
-
GSK-3β inhibition promotes engraftment of ex vivo expanded hematopoietic stem cells and modulates gene expression
-
Ko, K. H., Holmes, T., Palladinetti, P., Song, E., Nordon, R., O'Brien, T. A., and Dolnikov, A. (2011) GSK-3β inhibition promotes engraftment of ex vivo expanded hematopoietic stem cells and modulates gene expression. Stem Cells 29, 108-118
-
(2011)
Stem Cells
, vol.29
, pp. 108-118
-
-
Ko, K.H.1
Holmes, T.2
Palladinetti, P.3
Song, E.4
Nordon, R.5
O'Brien, T.A.6
Dolnikov, A.7
-
22
-
-
80052281899
-
Kip1 cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70
-
Kip1 cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell 9, 247-261
-
(2011)
Cell Stem Cell
, vol.9
, pp. 247-261
-
-
Zou, P.1
Yoshihara, H.2
Hosokawa, K.3
Tai, I.4
Shinmyozu, K.5
Tsukahara, F.6
Maru, Y.7
Nakayama, K.8
Nakayama, K.I.9
Suda, T.10
-
23
-
-
1642499734
-
β-Catenin is dispensable for hematopoiesis and lymphopoiesis
-
Cobas, M., Wilson, A., Ernst, B., Mancini, S. J., MacDonald, H. R., Kemler, R., and Radtke, F. (2004) β-Catenin is dispensable for hematopoiesis and lymphopoiesis. J. Exp. Med. 199, 221-229
-
(2004)
J. Exp. Med.
, vol.199
, pp. 221-229
-
-
Cobas, M.1
Wilson, A.2
Ernst, B.3
Mancini, S.J.4
MacDonald, H.R.5
Kemler, R.6
Radtke, F.7
-
24
-
-
33748850636
-
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
-
Kirstetter, P., Anderson, K., Porse, B. T., Jacobsen, S. E., and Nerlov, C. (2006) Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat. Immunol. 7, 1048-1056
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1048-1056
-
-
Kirstetter, P.1
Anderson, K.2
Porse, B.T.3
Jacobsen, S.E.4
Nerlov, C.5
-
25
-
-
38049139201
-
Simultaneous loss of β- and γ-catenin does not perturb hematopoiesis or lymphopoiesis
-
Koch, U., Wilson, A., Cobas, M., Kemler, R., Macdonald, H. R., and Radtke, F. (2008) Simultaneous loss of β- and γ-catenin does not perturb hematopoiesis or lymphopoiesis. Blood 111, 160-164
-
(2008)
Blood
, vol.111
, pp. 160-164
-
-
Koch, U.1
Wilson, A.2
Cobas, M.3
Kemler, R.4
Macdonald, H.R.5
Radtke, F.6
-
26
-
-
80052300618
-
Regulation of human epidermal stem cell proliferation and senescence requires Polycomb-dependent and -independent functions of Cbx4
-
Luis, N. M., Morey, L., Mejetta, S., Pascual, G., Janich, P., Kuebler, B., Cozutto, L., Roma, G., Nascimento, E., Frye, M., Di Croce, L., and Benitah, S. A. (2011) Regulation of human epidermal stem cell proliferation and senescence requires Polycomb-dependent and -independent functions of Cbx4. Cell Stem Cell 9, 233-246
-
(2011)
Cell Stem Cell
, vol.9
, pp. 233-246
-
-
Luis, N.M.1
Morey, L.2
Mejetta, S.3
Pascual, G.4
Janich, P.5
Kuebler, B.6
Cozutto, L.7
Roma, G.8
Nascimento, E.9
Frye, M.10
Di Croce, L.11
Benitah, S.A.12
-
27
-
-
84856738988
-
Hematopoiesis: A human perspective
-
Doulatov, S., Notta, F., Laurenti, E., and Dick, J. E. (2012) Hematopoiesis: a human perspective. Cell Stem Cell 10, 120-136
-
(2012)
Cell Stem Cell
, vol.10
, pp. 120-136
-
-
Doulatov, S.1
Notta, F.2
Laurenti, E.3
Dick, J.E.4
-
28
-
-
32944479985
-
Umbilical cord blood transplantation and banking
-
Brunstein, C. G., and Wagner, J. E. (2006) Umbilical cord blood transplantation and banking. Annu. Rev. Med. 57, 403-417
-
(2006)
Annu. Rev. Med.
, vol.57
, pp. 403-417
-
-
Brunstein, C.G.1
Wagner, J.E.2
-
29
-
-
79960106880
-
Isolation of single human hematopoietic stem cells capable of longterm multilineage engraftment
-
Notta, F., Doulatov, S., Laurenti, E., Poeppl, A., Jurisica, I., and Dick, J. E. (2011) Isolation of single human hematopoietic stem cells capable of longterm multilineage engraftment. Science 333, 218-221
-
(2011)
Science
, vol.333
, pp. 218-221
-
-
Notta, F.1
Doulatov, S.2
Laurenti, E.3
Poeppl, A.4
Jurisica, I.5
Dick, J.E.6
-
30
-
-
58049216794
-
p53 regulates hematopoietic stem cell quiescence
-
Liu, Y., Elf, S. E., Miyata, Y., Sashida, G., Liu, Y., Huang, G., Di Giandomenico, S., Lee, J. M., Deblasio, A., Menendez, S., Antipin, J., Reva, B., Koff, A., and Nimer, S. D. (2009) p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell 4, 37-48
-
(2009)
Cell Stem Cell
, vol.4
, pp. 37-48
-
-
Liu, Y.1
Elf, S.E.2
Miyata, Y.3
Sashida, G.4
Liu, Y.5
Huang, G.6
Di Giandomenico, S.7
Lee, J.M.8
Deblasio, A.9
Menendez, S.10
Antipin, J.11
Reva, B.12
Koff, A.13
Nimer, S.D.14
-
31
-
-
39749178390
-
Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo
-
Fleming, H. E., Janzen, V., Lo Celso, C., Guo, J., Leahy, K. M., Kronenberg, H. M., and Scadden, D. T. (2008) Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell 2, 274-283
-
(2008)
Cell Stem Cell
, vol.2
, pp. 274-283
-
-
Fleming, H.E.1
Janzen, V.2
Lo Celso, C.3
Guo, J.4
Leahy, K.M.5
Kronenberg, H.M.6
Scadden, D.T.7
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