Chronic hypoxia during gestation causes epigenetic repression of the estrogen receptor-α gene in ovine uterine arteries via heightened promoter methylation

Hypertension

Volumn 60, Issue 3, 2012, Pages 697-704

  Dasgupta, Chiranjib ^a   Chen, Man ^a   Zhang, Haitao ^a   Yang, Shumei ^b   Zhang, Lubo ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

epigenetic modulation; estrogen receptor; hypoxia; methylation; uterine artery

Indexed keywords

CPG DINUCLEOTIDE; DINUCLEOTIDE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; UPSTREAM STIMULATORY FACTOR 1; UPSTREAM STIMULATORY FACTOR 2;

ALTITUDE DISEASE; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CONTROLLED STUDY; EPIGENETICS; FEMALE; GENE DELETION; GENE REPRESSION; METHYLATION; MOLECULAR CLONING; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; SHEEP; TRANSCRIPTION INITIATION SITE; UTERINE ARTERY;

ANIMALS; ANOXIA; CPG ISLANDS; DNA METHYLATION; DOWN-REGULATION; ECLAMPSIA; EPIGENESIS, GENETIC; ESTROGEN RECEPTOR ALPHA; FEMALE; MODELS, ANIMAL; PREGNANCY; PREGNANCY, ANIMAL; PROMOTER REGIONS, GENETIC; RISK FACTORS; SHEEP; UPSTREAM STIMULATORY FACTORS; UTERINE ARTERY;

EID: 84865464431     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.198242     Document Type: Article

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