Uterine blood flow responses to ICI 182780 in ovariectomized oestradiol-17β-treated, intact follicular and pregnant sheep

Journal of Physiology

Volumn 565, Issue 1, 2005, Pages 71-83

  Magness, Ronald R ^a,b   Phernetton, Terrance M ^a   Gibson, Tiffini C ^a,b   Chen, Dong Bao ^a,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT; PROGESTERONE; PROSTAGLANDIN F2 ALPHA; SERIC GONADOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREEDING; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; DRUG MECHANISM; DRUG RESPONSE; FEMALE; FOLLICULAR PHASE; GESTATIONAL AGE; HEART RATE; HORMONE ACTION; IN VIVO STUDY; MEAN ARTERIAL PRESSURE; MOLECULAR MECHANICS; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN FUNCTION; SHEEP; UTERINE ARTERY; UTERUS BLOOD FLOW; VASODILATATION; CARDIOVASCULAR EFFECT; ESTRADIOL BLOOD LEVEL; EWE; THIRD TRIMESTER PREGNANCY; TIME; UTERINE VASCULAR RESISTANCE; VASCULAR RESISTANCE;

ANIMALS; BLOOD FLOW VELOCITY; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTROGEN RECEPTOR BETA; ESTROGEN RECEPTOR MODULATORS; FEMALE; FOLLICULAR PHASE; OVARIECTOMY; PLACENTAL CIRCULATION; PREGNANCY; PREGNANCY, ANIMAL; SHEEP; UTERUS; VASODILATION;

EID: 19444380527     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2005.086439     Document Type: Article

References (73)

1. Al-Matubsi HY, Fairclough RJ & Jenkin G (1998). Oestrogenic effects of ICI 182,780, a putative anti-oestrogen, on the secretion of oxytocin and prostaglandin F2 alpha during oestrous cycle in the intact ewe. Anim Reprod Sci 51, 81-96.
2. Byers MJ, Zangl A, Phernetton TM, Lopez G, Chen DB & Magness RR (2005). Endothelial vasodilator production by uterine and systemic arteries X: ovarian steroid and pregnancy control of ERa and ERb levels. J Physiol 000, 000-000.
3. Carnegie JA & Robertson HA (1978). Conjugated and unconjugated estrogens in fetal and maternal fluids of the pregnant ewe: a possible role for estrone sulfate during early pregnancy. Biol Reprod 19, 202-211.
4. Chambliss KL, Yuhanna IS, Anderson RG, Mendelsohn ME & Shaul PW (2002). ERbeta has nongenomic action in caveolae. Mol Endocrinol 16, 938-946.
5. Chen DB, Bird IM, Zheng J & Magness RR (2004). Membrane estrogen receptor-dependent extracellular signal-regulated kinase pathway mediates acute activation of endothelial nitric oxide synthase by estrogen in uterine artery endothelial cells. Endocrinology 145, 113-125.
6. Clark KE, Baker RS & Lang U (2000). Premarin-induced increases in coronary and uterine blood flow in nonpregnant sheep. Am J Obstet Gynecol 183, 12-17.
7. Edelstone DI, Botti JJ, Mueller-Heubach E & Caritis SN (1978). Response of the circulation of pregnant sheep to angiotensin and norepinephrine before and after dexamethasone. Am J Obstet Gynecol 130, 689-692.
8. Ford SP (1982). Control of uterine and ovarian blood flow throughout the estrous cycle and pregnancy of ewes, sows and cows. J Anim Sci 55 (Suppl. 2), 32-42.
9. Ford SP, Chenault JR & Echternkamp SE (1979a). Uterine blood flow of cows during the oestrous cycle and early pregnancy: effect of the conceptus on the uterine blood supply. J Reprod Fertil 56, 53-62.
10. Ford SP, Christenson RK & Chenault JR (1979b). Patterns of blood flow to the uterus and ovaries of ewes during the period of luteal regression. J Anim Sci 49, 1510-1516.
11. Gibson TC, Phernetton TM, Wiltbank MC & Magness RR (2004). Development and use of an ovarian synchronization model to study the effects of endogenous estrogen and nitric oxide on uterine blood flow during ovarian cycles in sheep. Biol Reprod 70, 1886-1894.
12. Goldstein SR, Siddhanti S, Ciaccia AV & Plouffe L Jr (2000). A pharmacological review of selective oestrogen receptor modulators. Hum Reprod Update 6, 212-224.
13. Greiss FC & Anderson SG (1969). Uterine vascular changes during the ovarian cycle. Am J Obstet Gynecol103, 629-640.
14. Greiss FC Jr & Anderson SG (1970). Effect of ovarian hormones on the uterine vascular bed. Am J Obstet Gynecol 107, 829-836.
15. Hegele-Hartung C, Fritzemeier KH & Diel P (1997). Effects of a pure antiestrogen and progesterone on estrogen-mediated alterations of blood flow and progesterone receptor expression in the aorta of ovariectomized rabbits. J Steroid Biochem Mol Biol 63, 237-249.
16. Huckabee WE, Crenshaw C, Curet LB, Mann L & Barron DH (1970). The effect of exogenous oestrogen on the blood flow and oxygen consumption of the uterus of the non-pregnant ewe. Q J Exp Physiol Cogn Med Sci55, 16-24.
17. Ihionkhan CE, Chambliss KL, Gibson LL, Hahner LD, Mendelsohn ME & Shaul PW (2002). Estrogen causes dynamic alterations in endothelial estrogen receptor expression. Circ Res91, 814-820.
18. Ing NH & Tornesi MB (1997). Estradiol up-regulates estrogen receptor and progesterone receptor gene expression in specific ovine uterine cells. Biol Reprod56, 1205-1215.
19. Killam AP, Rosenfeld CR, Battaglia FC, Makowski EL & Meschia G (1973). Effect of estrogens on the uterine blood flow of oophorectomized ewes. Am J Obstet Gynecol115, 1045-1052.
20. Kuiper GG, Lemmen JG, Carlsson B, Corton JC, Safe SH, van der Saag PT, van der Burg B & Gustafsson JA (1998). Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 139, 4252-4263.
21. Levine MG, Miodovnik M & Clark KE (1984). Uterine vascular effects of estetrol in nonpregnant ewes. Am J Obstet Gynecol 148, 735-738.
22. Liao WX, Magness RR & Chen DB (2005). Expression of estrogen receptors-α and -β in the pregnant ovine uterine artery endothelial cells in vivo and in vitro. Biol Reprod 72, 530-537.
23. MacGregor JI & Jordan VC (1998). Basic guide to the mechanisms of antiestrogen action. Pharmacol Rev 50, 151-196.
24. Magness RR (1990). Ovarian secretion and vascular function. In Ovarian Secretions and Cardiovascular and Neurological Function, Serono Foundation Symposia, vol. 80, pp. 93-125. Raren Press, Norwell, MA, USA.
25. Magness RR & Ford SP (1982). Steroid concentrations in uterine lymph and uterine arterial plasma of gilts during the estrous cycle and early pregnancy. Biol Reprod 27, 871 877.
26. Magness RR & Ford SP (1983). Estrone, estradiol-17 beta and progesterone concentrations in uterine lymph and systemic blood throughout the porcine estrous cycle, J Anim Sci 57, 449-455.
27. Magness RR, Parker CR Jr & Rosenfeld CR (1993). Systemic and uterine responses to chronic infusion of estradiol-17 beta. Am J Physiol 265, E690-E698.
28. Magness RR, Phernetton TM & Zheng J (1998). Systemic and uterine blood flow distribution during prolonged infusion of 17beta-estradiol. Am J Physiol 275, H731-H743.
29. Magness RR & Rosenfeld CR (1988). Mechanisms for attenuated pressor responses to alpha-agonists in ovine pregnancy. Am J Obstet Gynecol 159, 252-261.
30. Magness RR & Rosenfeld CR (1989a). The role of steroid hormones in the control of uterine blood flow. In Reproductive and Perinatal Medicine, vol. X, ed. Rosenfeld CR. pp. 234-271. Perinatoogy Press, Ithaca, NY.
31. Magness RR & Rosenfeld CR (1989b). Local and systemic estradiol-17 beta: effects on uterine and systemic vasodilation. Am J Physiol 256, E536-E542.
32. Magness RR & Rosenfeld CR (1992). Steroid control of blood vessel function. In Endometrial Function and Dysfunctional Uterine Bleeding, ed. Meeting NACDA-NIH, pp: 107-120. American Association for the Advancement of Science Press, Washington DC.
33. Magness RR, Rosenfeld CR & Carr BR (1991). Protein kinase C in uterine and systemic arteries during ovarian cycle and pregnancy. Am J Physiol 260, E464-E470.
34. Magness RR, Rosenfeld CR, Hassan A & Shaul PW (1996). Endothelial vasodilator production by uterine and systemic arteries. I. Effects of ANG II on PGI2 and NO in pregnancy. Am J Physiol 270, H1914-H1923.
35. Magness RR, Shaw CE, Phernetton TM, Zheng J & Bird IM (1997). Endothelial vasodilator production by uterine and systemic arteries. II. Pregnancy effects on NO synthase expression. Am J Physiol 272, H1730-H1740.
36. Magness RR, Sullivan JA, Li Y, Phernetton TM & Bird IM (2001). Endothelial vasodilator production by uterine and systemic arteries. VI. Ovarian and pregnancy effects on eNOS and NO (x). Am J Physiol Heart Circ Physiol 280, H1692-H1698.
37. Magness RR & Zheng J (1996). Maternal Cardiovascular Alterations During Pregnancy. Arnold Publishing, London.
38. Markee JE (1932). Rhythmic uterine vascular changes. Am J Physiol 100, 32-39.
39. Mershon JL, Baker RS & Clark KE (2002). Estrogen increases iNOS expression in the ovine coronary artery. Am J Physiol Heart Circ Physiol 283, H1169-H1180.
40. Miller SL, Jenkin G & Walker DW (1999). Effect of nitric oxide synthase inhibition on the uterine vasculature of the late-pregnant ewe. Am J Obstet Gynecol 180, 1138-1145.
41. Monheit AG & Resnik R (1981). Corticosteroid suppression of estrogen-induced uterine blood flow in nonpregnant sheep. Am J Obstet Gynecol 139 454-458.
42. Preisler-Mashek MT, Solodin N, Stark BL, Tyriver MK & Alarid ET (2002). Ligand-specific regulation of proteasome-mediated proteolysis of estrogen receptor-alpha. Am J Physiol Endocrinol Metab 282, E891-E898.
43. Qiu J, Bosch MA, Tobias SC, Grandy DK, Scanlan TS, Ronnekleiv OK & Kelly MJ (2003). Rapid signaling of estrogen in hypothalamic neurons involves a novel G-protein-coupled estrogen receptor that activates protein kinase C. J Neurosci 23, 9529-9540.
44. Resnik R, Brink GW & Plumer MH (1977). The effect of progesterone on estrogen-induced uterine blood flow. Am J Obstet Gynecol 128, 251-254.
45. Resnik R, Killam AP, Barton MD, Battaglia FC, Makowski EL & Meschia G (1976). The effect of various vasoactive compounds upon the uterine vascular bed. Am J Obstet Gynecol 125, 201-206.
46. Resnik R, Killam AP, Battaglia FC, Makowski EL & Meschia G (1974). The stimulation of uterine blood flow by various estrogens. Endocrinology 94, 1192-1196.
47. Reynolds LP, Kirsch JD, Kraft KC & Redmer DA (1998). Time-course of the uterine response to estradiol- 17beta in ovariectomized ewes: expression of angiogenic factors. Biol Reprod 59, 613-620
48. Reynolds LP & Redmer DA (2001). Angiogenesis in the placenta. Biol Reprod 64, 1033-1040.
49. Roman-Ponce H, Caton D, Thatcher WW & Lehrer R (1983). Uterine blood flow in relation to endogenous hormones during estrous cycle and early pregnancy. Am J Physiol 245, R843-R849.
50. + channels modulate basal and E(2)beta-induced rises in uterine blood flow in ovine pregnancy. Am J Physiol Heart Circ Physiol 281, H422-H431.
51. Rosenfeld CR, Cox BE, Roy T & Magness RR (1996). Nitric oxide contributes to estrogen-induced vasodilation of the ovine uterine circulation. J Clin Invest 98, 2158-2166.
52. Rosenfeld CR & Jackson GM (1982). Induction and inhibition of uterine vasodilation by catechol estrogen in oophorectomized, nonpregnant ewes. Endocrinology 110, 1333-1339.
53. Rosenfeld CR & Rivera R (1978). Circulatory responses to systemic infusions of estrone and estradiol-17 alpha in nonpregnant, oophorectomized ewes. Am J Obstet Gynecol 132, 442-448.
54. Rosenfeld CR, Roy T & Cox BE (2002). Mechanisms modulating estrogen-induced uterine vasodilation. Vascul Pharmacol 38, 115-125.
55. Rosenfeld CR, White RE, Roy T & Cox BE (2000). Calcium-activated potassium channels and nitric oxide coregulate estrogen-induced vasodilation. Am J Physiol Heart Circ Physiol 279, H319-H328.
56. Rupnow HL, Phernetton TM, Shaw CE, Modrick ML, Bird IM & Magness RR (2001). Endothelial vasodilator production by uterine and systemic arteries. VII. Estrogen and progesterone effects on eNOS. Am J Physiol Heart Circ Physiol 280, H1699-H1705.
57. Salhab WA, Shaul PW, Cox BE & Rosenfeld CR (2000). Regulation of types I and III NOS in ovine uterine arteries by daily and acute estrogen exposure. Am J Physiol Heart Circ Physiol 278, H2134-H2142.
58. Sawada M, Alkayed NJ, Goto S, Crain BJ, Traystman RJ, Shaivitz A, Nelson RJ & Hurn PD (2000). Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouse. J Cereb Blood Flow Metab 20, 112-118.
59. Souza CJ, Campbell BK & Baird DT (1998). Follicular waves and concentrations of steroids and inhibin A in ovarian venous blood during the luteal phase of the oestrous cycle in ewes with an ovarian autotransplant. J Endocrinol 156, 563-572.
60. Spencer TE & Bazer FW (1995). Temporal and spatial alterations in uterine estrogen receptor and progesterone receptor gene expression during the estrous cycle and early pregnancy in the ewe. Biol Reprod 53, 1527-1543.
61. Still JG & Greiss FC (1976). Effects of Cis- and transclomiphene on the uterine blood flow of oophorectomized ewes. Gynecol Invest 7, 187-200.
62. Sudhir K, Chou TM, Mullen WL, Hausmann D, Collins P, Yock PG & Chatterjee K (1995). Mechanisms of estrogen-induced vasodilation: in vivo studies in canine coronary conductance and resistance arteries. J Am Coll Cardiol 26, 807-814.
63. Teoh H, Leung SW & Man RY (1999). Short-term exposure to physiological levels of 17 beta-estradiol enhances endothelium-independent relaxation in porcine coronary artery. Cardiovasc Res 42, 224-231.
64. Thomas P, Pang Y, Filardo EJ & Dong J (2005). Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146, 624-632.
65. Tschugguel W, Dietrich W, Zhegu Z, Stonek F, Kolbus A & Huber JC (2003). Differential regulation of proteasome-dependent estrogen receptor alpha and beta turnover in cultured human uterine artery endothelial cells. J Clin Endocrinol Metab 88, 2281-2287.
66. Vagnoni KE, Shaw CE, Phernetton TM, Meglin BM, Bird IM & Magness RR (1998). Endothelial vasodilator production by uterine and systemic arteries. III. Ovarian and estrogen effects on NO synthase. Am J Physiol 275, H1845-H1856.
67. Van Buren GA, Yang DS & Clark KE (1992). Estrogen-induced uterine vasodilatation is antagonized by L-nitroarginine methyl ester, an inhibitor of nitric oxide synthesis. Am J Obstet Gynecol 167, 828-833.
68. Wakeling AE & Bowler J (1987). Steroidal pure antioestrogens. J Endocrinol 112, R7-R10.
69. Wakeling AE & Bowler J (1992). ICI 182;780, a new antioestrogen with clinical potential. J Steroid Biochem Mol Biol 43, 173-177.
70. Zhai P, Eurell TE, Cotthaus RP, Jeffery EH, Bahr JM & Gross DR (2001). Effects of dietary phytoestrogen on global myocardial ischemia-reperfusion injury in isolated female rat hearts. Am J Physiol Heart Circ Physiol 281, H1223-H1232.
71. Zheng J, Li Y, Weiss AR, Bird IM & Magness RR (2000). Expression of endothelial and inducible nitric oxide synthases and nitric oxide production in ovine placental and uterine tissues during late pregnancy. Placenta 21, 516-524.
72. Zoma WD, Baker RS & Clark KE (2000). Coronary and uterine vascular responses to raloxifene in the sheep. Am J Obstet Gynecol 182, 521-528.
73. Zoma W, Baker RS, Lang U & Clark KE (2001). Hemodynamic response to tibolone in reproductive and nonreproductive tissues in the sheep. Am J Obstet Gynecol 184, 544-551.