Nursing during the first two days of life is essential for the expression of proteins important for growth and remodeling of the neonatal porcine cervix

Endocrinology

Volumn 153, Issue 9, 2012, Pages 4511-4521

  Frankshun, Amy Lynn ^a   Chen, Joseph ^a   Barron, Lauren A ^a   Ho, Teh Yuan ^a   Miller, Dori J ^b   Rahman, Kathleen M ^a   Bartol, Frank F ^b   Bagnell, Carol A ^a  

^a RUTGERS UNIVERSITY   (United States)

^b AUBURN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL LYMPHOMA 2 PROTEIN; ESTROGEN RECEPTOR ALPHA; GELATINASE A; GELATINASE B; MESSENGER RNA; MOLECULAR MARKER; PROTEIN; RELAXIN; RXFP1 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

AGE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST FEEDING; CONTROLLED STUDY; FEMALE; GENE PRODUCT; NEWBORN; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SWINE; TISSUES; UTERINE CERVIX;

ANIMALS; ANIMALS, NEWBORN; CERVIX UTERI; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOBLOTTING; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; POLYMERASE CHAIN REACTION; RELAXIN; SWINE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84865438517     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1329     Document Type: Article

References (50)

1. Taylor HS, Vanden Heuvel GB, Igarashi P 1997 A conserved Hox axis in the mouse and human female reproductive system: late establishment and persistent adult expression of the Hoxa cluster genes. Biol Reprod 57:1338-1345 (Pubitemid 27516636)
2. Burggren W 1999 Genetic, environmental and maternal influences on embryonic cardiac rhythms. Comp Biochem Physiol A Mol Integr Physiol 124:423-427 (Pubitemid 30001970)
3. Bartol FF, Wiley AA, Bagnell CA 2008 Epigenetic programming of porcine endometrial function and the lactocrine hypothesis. Reprod Domest Anim 43(Suppl 2):273-279
4. Winn RJ, Baker MD, Sherwood OD 1994 Individual and combined effects of relaxin, estrogen, and progesterone in ovariectomized gilts. I. Effects on the growth, softening, and histological properties of the cervix. Endocrinology 135:1241-1249 (Pubitemid 24271222)
5. Winn RJ, O'Day-Bowman MB, Sherwood OD 1993 Hormonal control of the cervix in pregnant gilts. IV. Relaxin promotes changes in the histological characteristics of the cervix that are associated with cervical softening during late pregnancy in gilts. Endocrinology 133: 121-128 (Pubitemid 23206383)
6. O'Day MB, Winn RJ, Easter RA, Dziuk PJ, Sherwood OD 1989 Hormonal control of the cervix in pregnant gilts. II. Relaxin promotes changes in the physical properties of the cervix in ovariectomized hormone-treated pregnant gilts. Endocrinology 125:3004-3010 (Pubitemid 20010676)
7. O'Day-Bowman MB, Winn RJ, Dziuk PJ, Lindley ER, Sherwood OD 1991 Hormonal control of the cervix in pregnant gilts. III. Relaxin's influence on cervical biochemical properties in ovariectomized hormone-treated pregnant gilts. Endocrinology 129:1967-1976
8. Eldridge-White R, Easter RA, Heaton DM, O'Day MB, Petersen GC, Shanks RD, Tarbell MK, Sherwood OD 1989 Hormonal control of the cervix in pregnant gilts. I. Changes in the physical properties of the cervix correlate temporally with elevated serum levels of estrogen and relaxin. Endocrinology 125:2996-3003 (Pubitemid 20010675)
9. Yan W, Chen J, Wiley AA, Crean-Harris BD, Bartol FF, Bagnell CA 2008 Relaxin (RLX) and estrogen affect estrogen receptor α, vascular endothelial growth factor, and RLX receptor expression in the neonatal porcine uterus and cervix. Reproduction 135:705-712 (Pubitemid 351676453)
10. Lenhart JA, Ryan PL, Ohleth KM, Palmer SS, Bagnell CA 2001 Relaxin increases secretion of matrix metalloproteinase-2 and matrix metalloproteinase-9 during uterine and cervical growth and remodeling in the pig. Endocrinology 142:3941-3949 (Pubitemid 32802667)
11. Bartol FF, Wiley AA, Bagnell CA 2006 Uterine development and endometrial programming. In: Asworth CJ, Kraeling RR, eds. Control of pig reproduction VII. Nottingham, UK: Nottingham University Press; 113-130
12. Yan W, Ryan PL, Bartol FF, Bagnell CA 2006 Uterotrophic effects of relaxin related to age and estrogen receptor activation in neonatal pigs. Reproduction 131:943-950 (Pubitemid 43805437)
13. Yan W, Wiley AA, Bartol FF, Bagnell CA 2005 Tissue-specific effects of relaxin on the reproductive tract of neonatal gilts. Ann NY Acad Sci 1041:132-135 (Pubitemid 41132237)
14. Bartol FF, Bagnell CA 2012 Lactocrine programming of female reproductive tract development: environmental connections to the reproductive continuum. Mol Cell Endocrinol 354:16-21
15. Forsberg JG 1969 The development of atypical epithelium in the mouse uterine cervix and vaginal fornix after neonatal oestradiol treatment. Br J Exp Pathol 50:187-195
16. Yan W, Ryan PL, Bagnell CA 2002 Tissue-specific effects of relaxin on the reproductive tract of neonatal pigs: estrogen receptor-dependent and independent actions. Biol Reprod 66(Suppl 1):202
17. Chen JC, Wiley AA, Ho TY, Frankshun AL, Hord KM, Bartol FF, Bagnell CA 2010 Transient estrogen exposure from birth affects uterine expression of developmental markers in neonatal gilts with lasting consequences in pregnant adults. Reproduction 139:623-630
18. Bartol FF, Wiley AA, Spencer TE, Vallet JL, Christenson RK 1993 Early uterine development in pigs. J Reprod Fertil Suppl 48:99-116
19. Danielsen M, Pedersen LJ, Bendixen E 2011 An in vivo characterization of colostrum protein uptake in porcine gut during early lactation. J Proteomics 74:101-109
20. Klobasa F, Werhahn E, Butler JE 1987 Composition of sow milk during lactation. J Anim Sci 64:1458-1466
21. Wu WZ, Wang XQ, Wu GY, Kim SW, Chen F, Wang JJ 2010 Differential composition of proteomes in sow colostrum and milk from anterior and posterior mammary glands. J Anim Sci 88:2657-2664
22. Donovan SM, Odle J 1994 Growth factors in milk as mediators of infant development. Annu Rev Nutr 14:147-167 (Pubitemid 24261834)
23. Frankshun AL, Ho TY, Steinetz BG, Bartol FF, Bagnell CA 2009 Biological activity of relaxin in porcine milk. Ann NY Acad Sci 1160:164-168
24. Yan W, Wiley AA, Bathgate RA, Frankshun AL, Lasano S, Crean BD, Steinetz BG, Bagnell CA, Bartol FF 2006 Expression of LGR7 and LGR8 by neonatal porcine uterine tissues and transmission of milk-borne relaxin into the neonatal circulation by suckling. Endocrinology 147:4303-4310 (Pubitemid 44268381)
25. Frankshun AL, Ho TY, Reimer DC, Chen J, Lasano S, Steinetz BG, Bartol FF, Bagnell CA 2011 Characterization and biological activity of relaxin in porcine milk. Reproduction 141:373-380
26. Leece JG 1973 Effect of dietary regimen on cessation of uptake of macromolecules by piglet intestinal epithelium (closure) and transport to the blood. J Nutr 103:751-756
27. Bagnell CA, Steinetz BG, Bartol FF 2009 Milk-borne relaxin and the lactocrine hypothesis for maternal programming of neonatal tissues. Ann NY Acad Sci 1160:152-157
28. Chen JC, Frankshun AL, Wiley AA, Miller DJ, Welch KA, Ho TY, Bartol FF, Bagnell CA 2011 Milk-borne lactocrine-acting factors affect gene expression patterns in the developing neonatal porcine uterus. Reproduction 141:675-683
29. Osterlundh I, Holst H, Magnusson U 1998 Hormonal and immunological changes in blood and mammary secretion in the sow at parturition. Theriogenology 50:465-477 (Pubitemid 28402817)
30. Bartol FF, Wiley AA, Bagnell CA 2006 Uterine development and endometrial programming. Reproduction 62:113-130
31. Rehfeldt C, Kuhn G 2006 Consequences of birth weight for postnatal growth performance and carcass quality in pigs as related to myogenesis. J Anim Sci 84:E113-E123
32. Houle VM, Park YK, Laswell SC, Freund GG, Dudley MA, Donovan SM 2000 Investigation of three doses of oral insulin-like growth factor-I on jejunal lactase phlorizin hydrolase activity and gene expression and enterocyte proliferation and migration in piglets. Pediatr Res 48:497-503
33. Burrin DG, Stoll B, Guan X, Cui L, Chang X, Holst JJ 2005 Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets. Endocrinology 146: 22-32 (Pubitemid 40051718)
34. Cook SA, Sugden PH, Clerk A 1999 Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential. Circ Res 85:940-949 (Pubitemid 29534169)
35. Guan RJ, Moss SF, Arber N, Krajewski S, Reed JC, Holt PR 1996 30 KDa phosphorylated form of Bcl-2 protein in human colon. Oncogene 12:2605-2609 (Pubitemid 26237789)
36. Crabbe T, Ioannou C, Docherty AJ 1993 Human progelatinase A can be activated by autolysis at a rate that is concentration-dependent and enhanced by heparin bound to the C-terminal domain. Eur J Biochem 218:431-438 (Pubitemid 24003757)
37. O'Connell JP, Willenbrock F, Docherty AJ, Eaton D, Murphy G 1994 Analysis of the role of the COOH-terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B. J Biol Chem 269:14967-14973 (Pubitemid 24198336)
38. Zhao S, Fields PA, Sherwood OD 2001 Evidence that relaxin inhibits apoptosis in the cervix and the vagina during the second half of pregnancy in the rat. Endocrinology 142:2221-2229 (Pubitemid 32473075)
39. Yao L, Agoulnik AI, Cooke PS, Meling DD, Sherwood OD 2008 Relaxin acts on stromal cells to promote epithelial and stromal proliferation and inhibit apoptosis in the mouse cervix and vagina. Endocrinology 149:2072-2079 (Pubitemid 351574527)
40. Moore XL, Tan SL, Lo CY, Fang L, Su YD, Gao XM, Woodcock EA, Summers RJ, Tregear GW, Bathgate RA, Du XJ 2007 Relaxin antagonizes hypertrophy and apoptosis in neonatal rat cardiomyocytes. Endocrinology 148:1582-1589 (Pubitemid 46457105)
41. Haldar S, Jena N, Croce CM 1995 Inactivation of Bcl-2 by phosphorylation. Proc Natl Acad Sci USA 92:4507-4511
42. Blagosklonny MV, Giannakakou P, el-Deiry WS, Kingston DG, Higgs PI, Neckers L, Fojo T 1997 Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death. Cancer Res 57:130-135 (Pubitemid 27020341)
43. Godlewski MM, Slupecka M, Wolinski J, Skrzypek T, Skrzypek H, Motyl T, Zabielski R 2005 Into the unknown - the death pathways in the neonatal gut epithelium. J Physiol Pharmacol 56(Suppl 3): 7-24 (Pubitemid 43129233)
44. Okada Y, Nakanishi I 1989 Activation of matrix metalloproteinase 3 (stromelysin) and matrix metalloproteinase 2 ('gelatinase') by human neutrophil elastase and cathepsin G. FEBS Lett 249:353-356 (Pubitemid 19143491)
45. Bartol FF, Wiley AA, Bagnell CA 2009 Relaxin and maternal lactocrine programming of neonatal uterine development. Ann NY Acad Sci 1160:158-163
46. Xu RJ, Mellor DJ, Tungthanathanich P, Birtles MJ, Reynolds GW, Simpson HV 1992 Growth and morphological changes in the small and the large intestine in piglets during the first three days after birth. J Dev Physiol 18:161-172 (Pubitemid 23102922)
47. Kosaka N, Izumi H, Sekine K, Ochiya T 2010 microRNA as a new immune-regulatory agent in breast milk. Silence 1:1-7
48. Grosvenor CE, Picciano MF, Baumrucker CR 1993 Hormones and growth factors in milk. Endocr Rev 14:710-728 (Pubitemid 24016658)
49. Koldovský O 1995 Hormones in milk. Vitam Horm 50:77-149
50. Chen X, Gao C, Li H, Huang L, Sun Q, Dong Y, Tian C, Gao S, Dong H, Guan D, Hu X, Zhao S, Li L, Zhu L, Yan Q, Zhang J, Zen K, Zhang CY 2010 Identification and characterisation of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products. Cell Res 20:1128-1137