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Volumn 135, Issue 5, 2008, Pages 705-712

Relaxin (RLX) and estrogen affect estrogen receptor α, vascular endothelial growth factor, and RLX receptor expression in the neonatal porcine uterus and cervix

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR; RELAXIN; RELAXIN RECEPTOR; VASCULOTROPIN;

EID: 43549110730     PISSN: 14701626     EISSN: None     Source Type: Journal    
DOI: 10.1530/REP-08-0014     Document Type: Article
Times cited : (36)

References (54)
  • 3
    • 0842312980 scopus 로고    scopus 로고
    • Phosphodiesterase 4 inhibition synergizes with relaxin signaling to promote decidualization of human endometrial stromal cells
    • Bartsch O, Bartlick B & Ivell R 2004 Phosphodiesterase 4 inhibition synergizes with relaxin signaling to promote decidualization of human endometrial stromal cells. Journal of Clinical Endocrinology and Metabolism 89 324-334.
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 324-334
    • Bartsch, O.1    Bartlick, B.2    Ivell, R.3
  • 4
    • 33644589069 scopus 로고    scopus 로고
    • International Union of Pharmacology LVII: Recommendations for the nomenclature of receptors for relaxin family peptides
    • Bathgate RA, Ivell R, Sanborn BM, Sherwood OD & Summers RJ 2006 International Union of Pharmacology LVII: Recommendations for the nomenclature of receptors for relaxin family peptides. Pharmacological Reviews 58 7-31.
    • (2006) Pharmacological Reviews , vol.58 , pp. 7-31
    • Bathgate, R.A.1    Ivell, R.2    Sanborn, B.M.3    Sherwood, O.D.4    Summers, R.J.5
  • 5
    • 24344507238 scopus 로고    scopus 로고
    • Estrogen receptors in the uterus and ovarian follicles of gilts treated with dihydrotestosterone
    • Cardenas H & Pope WF 2005 Estrogen receptors in the uterus and ovarian follicles of gilts treated with dihydrotestosterone. Domestic Animal Endocrinology 29 523-533.
    • (2005) Domestic Animal Endocrinology , vol.29 , pp. 523-533
    • Cardenas, H.1    Pope, W.F.2
  • 6
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice: What have we learned and where will they lead us?
    • Couse JF & Korach KS 1999 Estrogen receptor null mice: What have we learned and where will they lead us? Endocrine Reviews 20 358-417.
    • (1999) Endocrine Reviews , vol.20 , pp. 358-417
    • Couse, J.F.1    Korach, K.S.2
  • 7
    • 0027183674 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: Rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth
    • Cullinan-Bove K & Koos RD 1993 Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: Rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth. Endocrinology 133 829-837.
    • (1993) Endocrinology , vol.133 , pp. 829-837
    • Cullinan-Bove, K.1    Koos, R.D.2
  • 8
    • 0026767850 scopus 로고
    • Influence of ovarian steroids on myometrial sensitivity and tolerance to relaxin in the rat in vivo: Lack of cross-tolerance between relaxin, salbutamol and cromakalim
    • Downing SJ & Hollingsworth M 1992 Influence of ovarian steroids on myometrial sensitivity and tolerance to relaxin in the rat in vivo: Lack of cross-tolerance between relaxin, salbutamol and cromakalim. Journal of Endocrinology 135 17-28.
    • (1992) Journal of Endocrinology , vol.135 , pp. 17-28
    • Downing, S.J.1    Hollingsworth, M.2
  • 9
    • 0027426026 scopus 로고
    • Uptake of relaxin in the uterus and cervix of rats in vivo: Influence of ovarian steroids and tolerance
    • Downing SJ & Hollingsworth M 1993 Uptake of relaxin in the uterus and cervix of rats in vivo: Influence of ovarian steroids and tolerance. Journal of Reproduction and Fertility 99 121-129.
    • (1993) Journal of Reproduction and Fertility , vol.99 , pp. 121-129
    • Downing, S.J.1    Hollingsworth, M.2
  • 10
    • 0038228121 scopus 로고    scopus 로고
    • Relaxin is an important factor for uterine differentiation and implantation in the marmoset monkey
    • Eds GW Tregear, R Ivell, RA Bathgate & JD Wade. Dordrecht: Kluwer Academic Publishers
    • Einspanier A 2001 Relaxin is an important factor for uterine differentiation and implantation in the marmoset monkey. In Relaxin 2000, pp 73-82. Eds GW Tregear, R Ivell, RA Bathgate & JD Wade. Dordrecht: Kluwer Academic Publishers.
    • (2001) Relaxin 2000 , pp. 73-82
    • Einspanier, A.1
  • 11
    • 30944458435 scopus 로고    scopus 로고
    • Estrogen regulates transcription of the ovine oxytocin receptor gene through GC-rich SP1 promoter elements
    • Fleming JG, Spencer TE, Safe SH & Bazer FW 2006 Estrogen regulates transcription of the ovine oxytocin receptor gene through GC-rich SP1 promoter elements. Endocrinology 147 899-911.
    • (2006) Endocrinology , vol.147 , pp. 899-911
    • Fleming, J.G.1    Spencer, T.E.2    Safe, S.H.3    Bazer, F.W.4
  • 12
    • 0026040217 scopus 로고
    • The mechanism of ICI 164 384 antiestrogenicity involves rapid loss of estrogen receptor in uterine tissue
    • Gibson MK, Nemmers LA, Beckman WC Jr, Davis VL, Curtis SW & Korach KS 1991 The mechanism of ICI 164 384 antiestrogenicity involves rapid loss of estrogen receptor in uterine tissue. Endocrinology 129 2000-2010.
    • (1991) Endocrinology , vol.129 , pp. 2000-2010
    • Gibson, M.K.1    Nemmers, L.A.2    Beckman Jr, W.C.3    Davis, V.L.4    Curtis, S.W.5    Korach, K.S.6
  • 15
    • 0027209113 scopus 로고
    • Influence of ovarian steroids on relaxin-induced distensibility and compositional changes in the porcine cervix
    • Hall JA & Anthony RV 1993 Influence of ovarian steroids on relaxin-induced distensibility and compositional changes in the porcine cervix. Biology of Reproduction 48 1348-1353.
    • (1993) Biology of Reproduction , vol.48 , pp. 1348-1353
    • Hall, J.A.1    Anthony, R.V.2
  • 18
    • 0037739787 scopus 로고    scopus 로고
    • Domains of estrogen receptor alpha (ERalpha) required for ERalpha/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells
    • Kim K, Thu N, Saville B & Safe S 2003 Domains of estrogen receptor alpha (ERalpha) required for ERalpha/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells. Molecular Endocrinolgy 17 804-817.
    • (2003) Molecular Endocrinolgy , vol.17 , pp. 804-817
    • Kim, K.1    Thu, N.2    Saville, B.3    Safe, S.4
  • 19
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) method
    • Livalk KJ & Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) method. Methods 25 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livalk, K.J.1    Schmittgen, T.D.2
  • 20
    • 17744393003 scopus 로고    scopus 로고
    • Long-term effects of fetal exposure to low doses of the xenoestrogen bisphenol-A in the female mouse genital tract
    • Markey CM, Wadia PR, Rubin BS, Sonnenschein C & Soto AM 2005 Long-term effects of fetal exposure to low doses of the xenoestrogen bisphenol-A in the female mouse genital tract. Biology of Reproduction 72 1344-1351.
    • (2005) Biology of Reproduction , vol.72 , pp. 1344-1351
    • Markey, C.M.1    Wadia, P.R.2    Rubin, B.S.3    Sonnenschein, C.4    Soto, A.M.5
  • 21
    • 33845892553 scopus 로고    scopus 로고
    • Brain infusion of lipopolysaccharide increases uterine growth as a function of estrogen replacement regimen: Suppression of uterine estrogen receptor-alpha by constant, but not pulsed, estrogen replacement
    • Marriott LK, McCann-Gramling KR, Hauss-Wegrzyniak B, Sheldahl LC, Shapiro RA, Dorsa DM & Wenk GL 2007 Brain infusion of lipopolysaccharide increases uterine growth as a function of estrogen replacement regimen: Suppression of uterine estrogen receptor-alpha by constant, but not pulsed, estrogen replacement. Endocrinology 148 232-240.
    • (2007) Endocrinology , vol.148 , pp. 232-240
    • Marriott, L.K.1    McCann-Gramling, K.R.2    Hauss-Wegrzyniak, B.3    Sheldahl, L.C.4    Shapiro, R.A.5    Dorsa, D.M.6    Wenk, G.L.7
  • 23
    • 3242882918 scopus 로고    scopus 로고
    • Disparate effects of relaxin and TGFbeta1: Relaxin increases, but TGFbeta1 inhibits, the relaxin receptor and the production of IGFBP-1 in human endometrial stromal/ decidual cells
    • Mazella J, Tang M & Tseng L 2004 Disparate effects of relaxin and TGFbeta1: Relaxin increases, but TGFbeta1 inhibits, the relaxin receptor and the production of IGFBP-1 in human endometrial stromal/ decidual cells. Human Reproduction 19 1513-1518.
    • (2004) Human Reproduction , vol.19 , pp. 1513-1518
    • Mazella, J.1    Tang, M.2    Tseng, L.3
  • 24
  • 25
    • 0032541029 scopus 로고    scopus 로고
    • p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts
    • Milanini J, Vinals F, Pouyssegur J & Pages G 1998 p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts. Journal of Biological Chemistry 273 18165-18172.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 18165-18172
    • Milanini, J.1    Vinals, F.2    Pouyssegur, J.3    Pages, G.4
  • 26
    • 0031791874 scopus 로고    scopus 로고
    • Fetal exposure to DES results in de-regulation of Wnt7a during uterine morphogenesis
    • Miller C, Degenhardt K & Sassoon DA 1998 Fetal exposure to DES results in de-regulation of Wnt7a during uterine morphogenesis. Nature Genetics 20 228-230.
    • (1998) Nature Genetics , vol.20 , pp. 228-230
    • Miller, C.1    Degenhardt, K.2    Sassoon, D.A.3
  • 27
    • 0034034345 scopus 로고    scopus 로고
    • Differential distribution of oestrogen receptor-alpha and -beta mRNAs in the female reproductive organ of rats as revealed by in situ hybridization
    • Mowa CN & Iwanaga T 2000 Differential distribution of oestrogen receptor-alpha and -beta mRNAs in the female reproductive organ of rats as revealed by in situ hybridization. Journal of Endocrinology 165 59-66.
    • (2000) Journal of Endocrinology , vol.165 , pp. 59-66
    • Mowa, C.N.1    Iwanaga, T.2
  • 28
    • 17644374481 scopus 로고    scopus 로고
    • Effects of prepubertal exposure to xenoestrogen on development of estrogen target organs in female CD-1 mice
    • Nikaido Y, Danbara N, Tsujita-Kyutoku M, Yuri T, Uehara N & Tsubura A 2005 Effects of prepubertal exposure to xenoestrogen on development of estrogen target organs in female CD-1 mice. In Vivo 19 487-494.
    • (2005) In Vivo , vol.19 , pp. 487-494
    • Nikaido, Y.1    Danbara, N.2    Tsujita-Kyutoku, M.3    Yuri, T.4    Uehara, N.5    Tsubura, A.6
  • 29
    • 20444492865 scopus 로고    scopus 로고
    • Sex steroid hormone receptors in the developing female reproductive tract of laboratory rodents
    • Okada A, Sato T, Ohta Y & Iguchi T 2005 Sex steroid hormone receptors in the developing female reproductive tract of laboratory rodents. Journal of Toxicological Science 30 75-89.
    • (2005) Journal of Toxicological Science , vol.30 , pp. 75-89
    • Okada, A.1    Sato, T.2    Ohta, Y.3    Iguchi, T.4
  • 31
    • 0033316943 scopus 로고    scopus 로고
    • Relaxin stimulates uterine edema via activation of estrogen receptors: Blockade of its effects using ICI 182 780, a specific estrogen receptor antagonist
    • Pillai SB, Rockwell LC, Sherwood OD & Koos RD 1999 Relaxin stimulates uterine edema via activation of estrogen receptors: Blockade of its effects using ICI 182 780, a specific estrogen receptor antagonist. Endocrinology 140 2426-2429.
    • (1999) Endocrinology , vol.140 , pp. 2426-2429
    • Pillai, S.B.1    Rockwell, L.C.2    Sherwood, O.D.3    Koos, R.D.4
  • 32
    • 0036892889 scopus 로고    scopus 로고
    • Treatment of rats with 17beta-estradiol or relaxin rapidly inhibits uterine estrogen receptor beta1 and beta2 messenger ribonucleic acid levels
    • Pillai SB, Jones JM & Koos RD 2002 Treatment of rats with 17beta-estradiol or relaxin rapidly inhibits uterine estrogen receptor beta1 and beta2 messenger ribonucleic acid levels. Biology of Reproduction 67 1919-1926.
    • (2002) Biology of Reproduction , vol.67 , pp. 1919-1926
    • Pillai, S.B.1    Jones, J.M.2    Koos, R.D.3
  • 33
    • 0026795920 scopus 로고
    • Lack of effect of relaxin on oxytocin output from the porcine neural lobe in vitro or in lactating sows in vivo
    • Porter DG, Ryan PL & Norman L 1992 Lack of effect of relaxin on oxytocin output from the porcine neural lobe in vitro or in lactating sows in vivo. Journal of Reproduction and Fertility 96 251-260.
    • (1992) Journal of Reproduction and Fertility , vol.96 , pp. 251-260
    • Porter, D.G.1    Ryan, P.L.2    Norman, L.3
  • 34
    • 0004282518 scopus 로고    scopus 로고
    • SAS 2002-2003, Cary, NC: SAS Institute Inc
    • SAS 2002-2003 SAS/STAT User's Guide, Cary, NC: SAS Institute Inc.
    • SAS/STAT User's Guide
  • 35
    • 0036118303 scopus 로고    scopus 로고
    • In utero exposure to low doses of bisphenol A lead to long-term deleterious effects in the vagina
    • Schonfelder G, Flick B, Mayr E, Talsness C, Paul M & Chahoud I 2002 In utero exposure to low doses of bisphenol A lead to long-term deleterious effects in the vagina. Neoplasia 4 98-102.
    • (2002) Neoplasia , vol.4 , pp. 98-102
    • Schonfelder, G.1    Flick, B.2    Mayr, E.3    Talsness, C.4    Paul, M.5    Chahoud, I.6
  • 36
    • 3042610399 scopus 로고    scopus 로고
    • Relaxin's physiological roles and other diverse actions
    • Sherwood OD 2004 Relaxin's physiological roles and other diverse actions. Endocrine Reviews 25 205-234.
    • (2004) Endocrine Reviews , vol.25 , pp. 205-234
    • Sherwood, O.D.1
  • 38
    • 0035872399 scopus 로고    scopus 로고
    • Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma
    • Shi Q, Le X, Abbruzzese JL, Peng Z, Qian CN, Tang H, Xiong Q, Wang B, Li XC & Xie K 2001 Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma. Cancer Research 61 4143-4154.
    • (2001) Cancer Research , vol.61 , pp. 4143-4154
    • Shi, Q.1    Le, X.2    Abbruzzese, J.L.3    Peng, Z.4    Qian, C.N.5    Tang, H.6    Xiong, Q.7    Wang, B.8    Li, X.C.9    Xie, K.10
  • 39
    • 0026276438 scopus 로고
    • Nucleotide sequence of murine PCNA: Interspecies comparison of the cDNA and the 5′ flanking region of the gene
    • Shipman-Appasamy PM, Cohen KS & Prystowsky MB 1991 Nucleotide sequence of murine PCNA: Interspecies comparison of the cDNA and the 5′ flanking region of the gene. DNA Sequence 2 181-191.
    • (1991) DNA Sequence , vol.2 , pp. 181-191
    • Shipman-Appasamy, P.M.1    Cohen, K.S.2    Prystowsky, M.B.3
  • 40
    • 0141450620 scopus 로고    scopus 로고
    • Inhibition of oxytocin receptor and estrogen receptor-alpha expression, but not relaxin receptors (LGR7), in the myometrium of late pregnant relaxin gene knockout mice
    • Siebel AL, Gehring HM, Reytomas IGT & Parry LJ 2003 Inhibition of oxytocin receptor and estrogen receptor-alpha expression, but not relaxin receptors (LGR7), in the myometrium of late pregnant relaxin gene knockout mice. Endocrinology 144 4272-4275.
    • (2003) Endocrinology , vol.144 , pp. 4272-4275
    • Siebel, A.L.1    Gehring, H.M.2    Reytomas, I.G.T.3    Parry, L.J.4
  • 41
    • 0027512484 scopus 로고
    • Neonatal age and period of estrogen exposure affect porcine uterine growth, morphogenesis, and protein synthesis
    • Spencer TE, Wiley AA & Bartol FF 1993 Neonatal age and period of estrogen exposure affect porcine uterine growth, morphogenesis, and protein synthesis. Biology of Reproduction 48 741-751.
    • (1993) Biology of Reproduction , vol.48 , pp. 741-751
    • Spencer, T.E.1    Wiley, A.A.2    Bartol, F.F.3
  • 42
    • 0036011119 scopus 로고    scopus 로고
    • Developmental effects of perinatal exposure to bisphenol-A and diethylstilbestrol on reproductive organs in female mice
    • Suzuki A, Sugihara A, Uchida K, Sato T, Ohta Y, Katsu Y, Watanabe H & Iguchi T 2002 Developmental effects of perinatal exposure to bisphenol-A and diethylstilbestrol on reproductive organs in female mice. Reproductive Toxicology 16 107-116.
    • (2002) Reproductive Toxicology , vol.16 , pp. 107-116
    • Suzuki, A.1    Sugihara, A.2    Uchida, K.3    Sato, T.4    Ohta, Y.5    Katsu, Y.6    Watanabe, H.7    Iguchi, T.8
  • 44
    • 0033026319 scopus 로고    scopus 로고
    • Endometrial development and adenogenesis in the neonatal pig: Effects of estradiol valerate and the antiestrogen ICI 182 780
    • Tarleton BJ, Wiley AA & Bartol FF 1999 Endometrial development and adenogenesis in the neonatal pig: Effects of estradiol valerate and the antiestrogen ICI 182 780. Biology of Reproduction 61 253-263.
    • (1999) Biology of Reproduction , vol.61 , pp. 253-263
    • Tarleton, B.J.1    Wiley, A.A.2    Bartol, F.F.3
  • 45
    • 0034780673 scopus 로고    scopus 로고
    • Neonatal estradiol exposure alters uterine morphology and endometrial transcriptional activity in prepubertal gilts
    • Tarleton BJ, Wiley AA & Bartol FF 2001 Neonatal estradiol exposure alters uterine morphology and endometrial transcriptional activity in prepubertal gilts. Domestic Animal Endocrinology 21 111-125.
    • (2001) Domestic Animal Endocrinology , vol.21 , pp. 111-125
    • Tarleton, B.J.1    Wiley, A.A.2    Bartol, F.F.3
  • 46
    • 0037379494 scopus 로고    scopus 로고
    • Estrogen-induced disruption of neonatal porcine uterine development alters adult uterine function
    • Tarleton BJ, Braden TD, Wiley AA & Bartol FF 2003 Estrogen-induced disruption of neonatal porcine uterine development alters adult uterine function. Biology of Reproduction 68 1387-1393.
    • (2003) Biology of Reproduction , vol.68 , pp. 1387-1393
    • Tarleton, B.J.1    Braden, T.D.2    Wiley, A.A.3    Bartol, F.F.4
  • 47
    • 0033037935 scopus 로고    scopus 로고
    • Relaxin stimulates expression of vascular endothelial growth factor in normal human endometrial cells in vitro and is associated with menometrorrhagia in women
    • Unemori EN, Erikson ME, Rocco SE, Sutherland KM, Parsell DA, Mak J & Grove BH 1999 Relaxin stimulates expression of vascular endothelial growth factor in normal human endometrial cells in vitro and is associated with menometrorrhagia in women. Human Reproduction 14 800-806.
    • (1999) Human Reproduction , vol.14 , pp. 800-806
    • Unemori, E.N.1    Erikson, M.E.2    Rocco, S.E.3    Sutherland, K.M.4    Parsell, D.A.5    Mak, J.6    Grove, B.H.7
  • 49
    • 0023090792 scopus 로고
    • Growth-promoting effects of relaxin and related compositional changes inthe uterus, cervix, and vagina of the rat
    • Vasilenko P & Mead JP 1987 Growth-promoting effects of relaxin and related compositional changes inthe uterus, cervix, and vagina of the rat. Endocrinology 120 1370-1376.
    • (1987) Endocrinology , vol.120 , pp. 1370-1376
    • Vasilenko, P.1    Mead, J.P.2
  • 51
    • 37949037105 scopus 로고
    • Inhibition of the spontaneous uterine motility in vitro as a bioassay of relaxin
    • Wiqvist N & Paul KG 1958 Inhibition of the spontaneous uterine motility in vitro as a bioassay of relaxin. Acta Endocrinologica 29 135-146.
    • (1958) Acta Endocrinologica , vol.29 , pp. 135-146
    • Wiqvist, N.1    Paul, K.G.2
  • 52
    • 0024362634 scopus 로고
    • Developmental pattern of estrogen receptor expression in female mouse genital tracts
    • Yamashita S, Newbold RR, McLachlan JA & Korach KS 1989 Developmental pattern of estrogen receptor expression in female mouse genital tracts. Endocrinology 125 2888-2896.
    • (1989) Endocrinology , vol.125 , pp. 2888-2896
    • Yamashita, S.1    Newbold, R.R.2    McLachlan, J.A.3    Korach, K.S.4
  • 53
    • 33744463658 scopus 로고    scopus 로고
    • Uterotrophic effects of relaxin related to age and estrogen receptor activation in neonatal pigs
    • Yan W, Ryan PL, Bartol FF & Bagnell CA 2006a Uterotrophic effects of relaxin related to age and estrogen receptor activation in neonatal pigs. Reproduction 131 943-950.
    • (2006) Reproduction , vol.131 , pp. 943-950
    • Yan, W.1    Ryan, P.L.2    Bartol, F.F.3    Bagnell, C.A.4


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