Secondhand smoke exposure causes bronchial hyperreactivity via transcriptionally upregulated endothelin and 5-hydroxytryptamine 2A receptors

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Cao, Lei ^a   Zhang, Yaping ^a   Cao, Yong Xiao ^b   Edvinsson, Lars ^a   Xu, Cang Bao ^a  

^a LUND UNIVERSITY   (Sweden)

^b MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 (3,5 DIBROMO 4 HYDROXYBENZYLIDENE) 1,3 DIHYDRO 5 IODO 2 INDOLONE; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; RAF PROTEIN; SEROTONIN 2A RECEPTOR; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS HYPERREACTIVITY; BRONCHUS MUSCLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE SEQUENCE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PASSIVE SMOKING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RNA TRANSCRIPTION; RNA TRANSLATION; SMOOTH MUSCLE FIBER; TREATMENT RESPONSE;

ANIMALS; BRONCHIAL HYPERREACTIVITY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INDOLES; MALE; MUSCLE CONTRACTION; PHENOLS; RAF KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTOR, SEROTONIN, 5-HT2A; RNA, MESSENGER; SEROTONIN 5-HT2 RECEPTOR AGONISTS; TOBACCO SMOKE POLLUTION; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84865437694     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044170     Document Type: Article

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