Cigarette smoke upregulates rat coronary artery endothelin receptors in vivo

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Cao, Lei ^a   Zhang, Yaping ^a   Cao, Yong Xiao ^b   Edvinsson, Lars ^a   Xu, Cang Bao ^a  

^a LUND UNIVERSITY   (Sweden)

^b MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RAF PROTEIN; ENDOTHELIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORONARY ARTERY; CORRELATIONAL STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; IMMUNOFLUORESCENCE; IN VIVO STUDY; ISOLATED ARTERY; MALE; NONHUMAN; PASSIVE SMOKING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TISSUE DISTRIBUTION; UPREGULATION; VASOCONSTRICTION; WESTERN BLOTTING; ANIMAL; CORONARY BLOOD VESSEL; GENETICS; METABOLISM; PHOSPHORYLATION; SMOKE; SPRAGUE DAWLEY RAT; TOBACCO;

ANIMALIA; RATTUS;

ANIMALS; CORONARY VESSELS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ENDOTHELIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMOKE; TOBACCO; UP-REGULATION; VASOCONSTRICTION;

EID: 84863232911     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033008     Document Type: Article

References (42)

1. Prasad DS, Kabir Z, Dash AK, Das BC, (2009) Smoking and cardiovascular health: a review of the epidemiology, pathogenesis, prevention and control of tobacco. Indian J Med Sci 63: 520-533.
2. Ambrose JA, Barua RS, (2004) The pathophysiology of cigarette smoking and cardiovascular disease: an update. J Am Coll Cardiol 43: 1731-1737.
3. Campisi R, Czernin J, Schoder H, Sayre JW, Marengo FD, et al. (1998) Effects of long-term smoking on myocardial blood flow, coronary vasomotion, and vasodilator capacity. Circulation 98: 119-125.
4. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, et al. (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411-415.
5. Zhang Y, Edvinsson L, Xu CB, (2010) Up-regulation of endothelin receptors induced by cigarette smoke-involvement of MAPK in vascular and airway hyper-reactivity. ScientificWorldJournal 10: 2157-2166.
6. Xu CB, Lei Y, Chen Q, Pehrson C, Larsson L, et al. (2010) Cigarette smoke extracts promote vascular smooth muscle cell proliferation and enhances contractile responses in the vasculature and airway. Basic Clin Pharmacol Toxicol 107: 940-948.
7. Iwasa S, Fan J, Shimokama T, Nagata M, Watanabe T, (1999) Increased immunoreactivity of endothelin-1 and endothelin B receptor in human atherosclerotic lesions. A possible role in atherogenesis. Atherosclerosis 146: 93-100.
8. Dagassan PH, Breu V, Clozel M, Kunzli A, Vogt P, et al. (1996) Up-regulation of endothelin-B receptors in atherosclerotic human coronary arteries. J Cardiovasc Pharmacol 27: 147-153.
9. Kobayashi T, Miyauchi T, Iwasa S, Sakai S, Fan J, et al. (2000) Corresponding distributions of increased endothelin-B receptor expression and increased endothelin-1 expression in the aorta of apolipoprotein E-deficient mice with advanced atherosclerosis. Pathol Int 50: 929-936.
10. Wackenfors A, Emilson M, Ingemansson R, Hortobagyi T, Szok D, et al. (2004) Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries. Eur J Pharmacol 484: 103-109.
11. Rahman MM, Elmi S, Chang TK, Bai N, Sallam NA, et al. (2007) Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release. Vascul Pharmacol 46: 35-42.
12. Sandhu H, Xu CB, Edvinsson L, (2010) Upregulation of contractile endothelin type B receptors by lipid-soluble cigarette smoking particles in rat cerebral arteries via activation of MAPK. Toxicol Appl Pharmacol 249: 25-32.
13. Zhang JY, Cao L, Zheng XH, Xu CB, Cao YX, (2009) Dimethylsulfoxide-soluble smoking particles and nicotine affect vascular contractibility. Arch Pharm Res 32: 1475-1481.
14. Edvinsson LI, Povlsen GK, (2011) Vascular plasticity in cerebrovascular disorders. J Cereb Blood Flow Metab.
15. Huckle WR, Drag MD, Acker WR, Powers M, McFall RC, et al. (2001) Effects of L-749,329, an ET(A)/ET(B) endothelin receptor antagonist, in a porcine coronary artery injury model of vascular restenosis. Circulation 103: 1899-1905.
16. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, et al. (2001) Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22: 153-183.
17. Lewis TS, Shapiro PS, Ahn NG, (1998) Signal transduction through MAP kinase cascades. Adv Cancer Res 74: 49-139.
18. Lackey K, Cory M, Davis R, Frye SV, Harris PA, et al. (2000) The discovery of potent cRaf1 kinase inhibitors. Bioorg Med Chem Lett 10: 223-226.
19. Beg SA, Hansen-Schwartz JA, Vikman PJ, Xu CB, Edvinsson LI, (2006) ERK1/2 inhibition attenuates cerebral blood flow reduction and abolishes ET(B) and 5-HT(1B) receptor upregulation after subarachnoid hemorrhage in rat. J Cereb Blood Flow Metab 26: 846-856.
20. Chen QW, Edvinsson L, Xu CB, (2009) Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells. BMC Cell Biol 10: 52.
21. Henriksson M, Stenman E, Vikman P, Edvinsson L, (2007) MEK1/2 inhibition attenuates vascular ETA and ETB receptor alterations after cerebral ischaemia. Exp Brain Res 178: 470-476.
22. Adner M, Shankley N, Edvinsson L, (2001) Evidence that ET-1, but not ET-3 and S6b, ET(A)-receptor mediated contractions in isolated rat mesenteric arteries are modulated by co-activation of ET(B) receptors. Br J Pharmacol 133: 927-935.
23. Rahman MM, Laher I, (2007) Structural and functional alteration of blood vessels caused by cigarette smoking: an overview of molecular mechanisms. Curr Vasc Pharmacol 5: 276-292.
24. Haak T, Jungmann E, Raab C, Usadel KH, (1994) Elevated endothelin-1 levels after cigarette smoking. Metabolism 43: 267-269.
25. Tanus-Santos JE, Sampaio RC, Hyslop S, Franchini KG, Moreno H Jr, (2000) Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. Eur J Pharmacol 396: 33-37.
26. Quillen JE, Rossen JD, Oskarsson HJ, Minor RL Jr, Lopez AG, et al. (1993) Acute effect of cigarette smoking on the coronary circulation: constriction of epicardial and resistance vessels. J Am Coll Cardiol 22: 642-647.
27. Nohria A, Garrett L, Johnson W, Kinlay S, Ganz P, et al. (2003) Endothelin-1 and vascular tone in subjects with atherogenic risk factors. Hypertension 42: 43-48.
28. Cannan CR, Burnett JC Jr, Lerman A, (1996) Enhanced coronary vasoconstriction to endothelin-B-receptor activation in experimental congestive heart failure. Circulation 93: 646-651.
29. Eskesen K, Edvinsson L, (2006) Upregulation of endothelin ETB receptor-mediated vasoconstriction in rat coronary artery after organ culture. Eur J Pharmacol 539: 192-194.
30. Dimitrijevic I, Ekelund U, Edvinsson ML, Edvinsson L, (2009) Increased expression of endothelin ET(B) and angiotensin AT(1) receptors in peripheral resistance arteries of patients with suspected acute coronary syndrome. Heart Vessels 24: 393-398.
31. Dimitrijevic I, Edvinsson ML, Chen Q, Malmsjo M, Kimblad PO, et al. (2009) Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease. BMC Cardiovasc Disord 9: 40.
32. Barton M, (2000) Endothelial dysfunction and atherosclerosis: endothelin receptor antagonists as novel therapeutics. Curr Hypertens Rep 2: 84-91.
33. Fujita K, Matsumura Y, Miyazaki Y, Takaoka M, Morimoto S, (1996) Effects of the endothelin ETA-receptor antagonist FR139317 on development of hypertension and cardiovascular hypertrophy in deoxycorticosterone acetate-salt hypertensive rats. Jpn J Pharmacol 70: 313-319.
34. Kowala MC, Murugesan N, Tellew J, Carlson K, Monshizadegan H, et al. (2004) Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension. J Pharmacol Exp Ther 309: 275-284.
35. Dawson DA, Sugano H, McCarron RM, Hallenbeck JM, Spatz M, (1999) Endothelin receptor antagonist preserves microvascular perfusion and reduces ischemic brain damage following permanent focal ischemia. Neurochem Res 24: 1499-1505.
36. Hirano M, Osada S, Aoki T, Hirai S, Hosaka M, et al. (1996) MEK kinase is involved in tumor necrosis factor alpha-induced NF-kappaB activation and degradation of IkappaB-alpha. J Biol Chem 271: 13234-13238.
37. Edvinsson LI, Povlsen GK, (2011) Vascular plasticity in cerebrovascular disorders. J Cereb Blood Flow Metab 31: 1554-1571.
38. Chin PC, Liu L, Morrison BE, Siddiq A, Ratan RR, et al. (2004) The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism. J Neurochem 90: 595-608.
39. Lei Y, Cao YX, Xu CB, Zhang Y, (2008) The Raf-1 inhibitor GW5074 and dexamethasone suppress sidestream smoke-induced airway hyperresponsiveness in mice. Respir Res 9: 71.
40. Li J, Cao YX, Cao L, Liu Y, Xu CB, (2008) Heat stress alters G-protein coupled receptor-mediated function and endothelium-dependent relaxation in rat mesenteric artery. Eur J Pharmacol 588: 280-285.
41. Hansen-Schwartz J, Hoel NL, Zhou M, Xu CB, Svendgaard NA, et al. (2003) Subarachnoid hemorrhage enhances endothelin receptor expression and function in rat cerebral arteries. Neurosurgery 52: 1188-1194; 1194-1185.
42. Ansar S, Vikman P, Nielsen M, Edvinsson L, (2007) Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage. Am J Physiol Heart Circ Physiol 293: H3750-3758.