ApoE3 mediated polymeric nanoparticles containing curcumin: Apoptosis induced in vitro anticancer activity against neuroblastoma cells

International Journal of Pharmaceutics

Volumn 437, Issue 1-2, 2012, Pages 29-41

  Mulik, Rohit S ^a,c,d   Mönkkönen, Jukka ^c   Juvonen, Risto O ^c   Mahadik, Kakasaheb R ^a   Paradkar, Anant R ^b  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Apolipoprotein E3; Curcumin; Flow cytometry; Nanoparticles; Neuroblastoma

Indexed keywords

APOLIPOPROTEIN E3; CASPASE 3; CURCUMIN; ENBUCRILATE; NANOCARRIER; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG UPTAKE; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROBLASTOMA CELL; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; X RAY DIFFRACTION;

ANTINEOPLASTIC AGENTS; APOLIPOPROTEIN E3; APOPTOSIS; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CURCUMIN; DRUG CARRIERS; ENBUCRILATE; HUMANS; LIGANDS; NANOPARTICLES; NEUROBLASTOMA; REACTIVE OXYGEN SPECIES;

EID: 84865415662     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.07.062     Document Type: Article

References (36)

1. B.B. Aggarwal, A. Kumar, and A. Bharti Anticancer potential of curcumin: preclinical and clinical studies Anticancer Res. 23 2003 363 398
2. B.B. Aggarwal, S. Shishodia, and Y. Takada Curcumin suppresses the paclitaxel-induced nuclear factor-{kappa}B pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice Clin. Cancer Res. 11 2005 7490 7498
3. P. Anand, A.B. Kunnumakkara, R.A. Newman, and B.B. Aggarwal Bioavailability of curcumin: problems and promises Mol. Pharm. 4 2007 807 818
4. M.A. Azuine, and S.V. Bhide Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice Nutr. Cancer 17 1992 77 83
5. M. Bradford Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
6. T.M. Buttke, and P.M. Sandstrom Oxidative stress as a mediator of apoptosis Immunol. Today 15 1994 7 10
7. C. Chakraborty, B. Sarkar, C.H. Hsu, Z.H. Wen, C.S. Lin, and P.C. Shieh Future prospects of nanoparticles on brain targeted drug delivery J. Neurooncol. 93 2009 285 286
8. T. Dorai, Y.C. Cao, B. Dorai, R. Buttyan, and A.E. Katz Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo Prostate 47 2001 293 303
9. S. Ganta, and M. Amiji Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells Mol. Pharmacol. 6 2009 928 939
10. Y. Gupta, A. Jain, and S. Jain Transferrin-conjugated solid lipid nanoparticles for enhanced delivery of quinine dihydrochloride to the brain J. Pharm. Pharmacol. 59 2007 935 940
11. R.L. Gutman, G. Peacock, and R. Lu Targeted drug delivery for brain cancer treatment J. Control. Release 65 2000 31 41
12. M.D. Jacobson Reactive oxygen species and programmed cell death Trends Biochem. Sci. 21 1996 83 86
13. B. Joe, M. Vijaykumar, and B.R. Lokesh Biological properties of curcumin-cellular and molecular mechanisms of action Crit. Rev. Food Sci. Nutr. 44 2004 97 111
14. L. Juillerat-Jeanneret The targeted delivery of cancer drugs across the blood-brain barrier: chemical modifications of drugs or drug-nanoparticles? Drug Discovery Today 13 2008 1099 1106
15. J. Kim, J.M. Basak, and D.M. Holtzman The role of apolipoprotein E in alzheimer's disease Neuron 63 2009 287 303
16. J. Kreuter, D. Shamenkov, V. Petrov, P. Ramge, K. Cychutek, C. Koch-Brandt, and R. Alyautdin Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier J. Drug Target. 10 2002 317 325
17. A. Kunwar, A. Barik, B. Mishra, K. Rathinasamy, R. Pandey, and K.I. Priyadarsini Quantitative cellular uptake localization and cytotoxicity of curcumin in normal and tumor cells Biochim. Biophys. Acta 1780 2008 673 679
18. T.A. Lantto, M. Colucci, V. Závadová, R. Hiltunen, and A. Raasmaja Cytotoxicity of curcumin, resveratrol and plant extracts from basil juniper, laurel and parsley in SH-SY5Y and CV1-P cells Food Chem. 117 2009 405 411
19. G. Lee, D. Lee, K. Kang, C. Lee, H. Pyo, and T. Choi Preparation and characterization of bis-ethylhexyloxyphenolmethoxyphenyltriazine (bemt) loaded solid lipid nanoparticles (SLN) J. Ind. Eng. Chem. 13 2007 1180 1187
20. S. Lund-Katz, S. Wehrli, M. Zaiou, Y. Newhouse, K.H. Weisgraber, and M.C. Phillips Effects of polymorphism on the microenvironment of the LDL receptor-binding region of human apoE J. Lipid Res. 42 2001 894 901
21. K. Michaelis, M.M. Hoffmann, S. Dreis, E. Herbert, R.N. Alyautdin, M. Michaelis, J. Kreuter, and K. Langer Covalent linkage of apolipoprotein E to albumin nanoparticles strongly enhances drug transport into the brain J. Pharmacol. Exp. Ther. 317 2006 1246 1253
22. R. Mulik, K. Mahadik, and A. Paradkar Development of curcuminoids loaded poly(butyl) cyanoacrylate nanoparticles: physicochemical characterization and stability study Eur. J. Pharm. Sci. 37 2009 395 404
23. R.S. Mulik, J. Monkkonen, R.O. Juvonen, K.R. Mahadik, and A.R. Paradkar ApoE3 mediated poly(butyl) cyanoacrylate nanoparticles containing curcumin study of enhanced activity of curcumin against beta amyloid induced cytotoxicity using in vitro cell culture model Mol. Pharmacol. 7 2010 815 825
24. R.S. Mulik, J. Mönkkönen, R.O. Juvonen, K.R. Mahadik, and A.R. Paradkar Transferrin mediated solid lipid nanoparticles containing curcumin enhanced in vitro anticancer activity by induction of apoptosis Int. J. Pharm. 398 2010 190 203
25. C. Ramachandran, H.B. Fonseca, P. Jhabvala, E.A. Escalon, and S.J. Melnick Curcumin inhibits telomerase activity through human telomerase reverse transcriptase in MCF-7 breast cancer cell line Cancer Lett. 184 2002 1 6
26. L.H. Reddy, and R.S.R. Murthy Influence of polymerization technique and experimental variables on the particle properties and release kinetics of methotrexate from poly(butylcyanoacrylate) nanoparticles Acta Pharm. 54 2004 103 118
27. S.K. Sahoo, and V. Labhasetwar Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention Mol. Pharm. 2 2005 373 383
28. M. Shi, Q. Cai, L. Yao, Y. Mao, Y. Ming, and G. Ouyang Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells Cell Biol. Int. 30 2006 221 226
29. J. Skommer, D. Wlodkowic, and J. Pelkonen Cellular foundation of curcumin-induced apoptosis in follicular lymphoma cell lines Exp. Hematol. 34 2006 463 474
30. E.M. Van, L.W. Nieland, F.S. Ramaekers, B. Schutte, and C.M. Reutelingsperger Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine externalization Cytometry 31 1998 1 9
31. I. Vermes, C. Haanen, and C. Reutelingsperger Flow cytometry of apoptotic cell death J. Immunol. Methods 243 2000 167 190
32. H. Wang, and J.A. Joseph Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader Free Radic. Biol. Med. 27 1999 612 616
33. N.M. Weir, K. Selvendiran, and V.K. Kutala Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK Cancer Biol. Ther. 6 2007 178 184
34. J-H. Woo, Y-H. Kim, Y-J. Choi, D-G. Kim, K-S. Lee, J.H. Bae, D.S. Min, J-S. Chang, Y-J. Jeong, Y-H. Lee, J-W. Park, and T-K. Kwon Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome C and inhibition of Akt Carcinogenesis 24 2003 1199 1208
35. T. Yamamoto, H.-C. Chen, E. Guigard, C.M. Kay, and R.O. Ryan Molecular studies of pH-dependent ligand interactions with the low-density lipoprotein receptor Biochemistry 47 2008 11647 11652
36. A. Zensi, D. Begley, C. Pontikis, C. Legros, L. Mihoreanu, S. Wagner, C. Büchel, H. von Briesen, and J. Kreuter Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurons J. Control. Release 137 2009 78 86