Molecular studies of pH-dependent ligand interactions with the low-density lipoprotein receptor

Biochemistry

Volumn 47, Issue 44, 2008, Pages 11647-11652

  Yamamoto, Taichi ^a   Chen, Hsuan Chih ^a   Guigard, Emmanuel ^b   Kay, Cyril M ^b   Ryan, Robert O ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; BIOCHEMISTRY; DISCHARGE (FLUID MECHANICS); ENERGY TRANSFER; FLUORESCENCE; LIGHT EMISSION; LUMINESCENCE; PH; PH EFFECTS; PROBABILITY DENSITY FUNCTION; SEDIMENTATION; WINDOWS OPERATING SYSTEM;

APOLIPOPROTEIN E; BOUND LIGANDS; DATA SUPPORTS; DENSITY LIPOPROTEIN RECEPTORS; DOUBLE MUTANTS; FLUORESCENCE RESONANCE ENERGY TRANSFERS; INTRAMOLECULAR REARRANGEMENTS; LIGAND BINDINGS; LIGAND INTERACTIONS; MUTAGENESIS STUDIES; MUTANT RECEPTORS; PH RANGES; PH VALUES; POSITIVELY CHARGED; SEDIMENTATION COEFFICIENTS; SIDE CHAINS; TERMINAL DOMAINS;

LIGANDS;

ALANINE; APOLIPOPROTEIN E; HISTIDINE; LOW DENSITY LIPOPROTEIN RECEPTOR; TRYPTOPHAN;

ARTICLE; CONFORMATIONAL TRANSITION; FLUORESCENCE RESONANCE ENERGY TRANSFER; IONIZATION; LIGAND BINDING; PH; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEDIMENTATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; APOLIPOPROTEINS E; FLUORESCENCE RESONANCE ENERGY TRANSFER; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, LDL; RECOMBINANT PROTEINS; SOLUBILITY; TRYPTOPHAN;

EID: 55249114139     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801117t     Document Type: Article

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